KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129069687
Entry
129069687         CDS       T09558                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01522  Endocrine resistance
ppam04010  MAPK signaling pathway
ppam04012  ErbB signaling pathway
ppam04014  Ras signaling pathway
ppam04024  cAMP signaling pathway
ppam04068  FoxO signaling pathway
ppam04071  Sphingolipid signaling pathway
ppam04137  Mitophagy - animal
ppam04140  Autophagy - animal
ppam04141  Protein processing in endoplasmic reticulum
ppam04210  Apoptosis
ppam04215  Apoptosis - multiple species
ppam04217  Necroptosis
ppam04310  Wnt signaling pathway
ppam04380  Osteoclast differentiation
ppam04510  Focal adhesion
ppam04530  Tight junction
ppam04620  Toll-like receptor signaling pathway
ppam04621  NOD-like receptor signaling pathway
ppam04622  RIG-I-like receptor signaling pathway
ppam04625  C-type lectin receptor signaling pathway
ppam04657  IL-17 signaling pathway
ppam04658  Th1 and Th2 cell differentiation
ppam04659  Th17 cell differentiation
ppam04660  T cell receptor signaling pathway
ppam04664  Fc epsilon RI signaling pathway
ppam04668  TNF signaling pathway
ppam04722  Neurotrophin signaling pathway
ppam04723  Retrograde endocannabinoid signaling
ppam04728  Dopaminergic synapse
ppam04750  Inflammatory mediator regulation of TRP channels
ppam04910  Insulin signaling pathway
ppam04912  GnRH signaling pathway
ppam04914  Progesterone-mediated oocyte maturation
ppam04917  Prolactin signaling pathway
ppam04920  Adipocytokine signaling pathway
ppam04926  Relaxin signaling pathway
ppam04930  Type II diabetes mellitus
ppam04931  Insulin resistance
ppam04932  Non-alcoholic fatty liver disease
ppam04933  AGE-RAGE signaling pathway in diabetic complications
ppam04935  Growth hormone synthesis, secretion and action
ppam04936  Alcoholic liver disease
ppam05010  Alzheimer disease
ppam05012  Parkinson disease
ppam05016  Huntington disease
ppam05017  Spinocerebellar ataxia
ppam05020  Prion disease
ppam05022  Pathways of neurodegeneration - multiple diseases
ppam05132  Salmonella infection
ppam05133  Pertussis
ppam05135  Yersinia infection
ppam05142  Chagas disease
ppam05145  Toxoplasmosis
ppam05152  Tuberculosis
ppam05161  Hepatitis B
ppam05162  Measles
ppam05166  Human T-cell leukemia virus 1 infection
ppam05167  Kaposi sarcoma-associated herpesvirus infection
ppam05169  Epstein-Barr virus infection
ppam05170  Human immunodeficiency virus 1 infection
ppam05171  Coronavirus disease - COVID-19
ppam05200  Pathways in cancer
ppam05208  Chemical carcinogenesis - reactive oxygen species
ppam05210  Colorectal cancer
ppam05212  Pancreatic cancer
ppam05231  Choline metabolism in cancer
ppam05415  Diabetic cardiomyopathy
ppam05417  Lipid and atherosclerosis
ppam05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    129069687 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129069687 (MAPK8)
   04012 ErbB signaling pathway
    129069687 (MAPK8)
   04014 Ras signaling pathway
    129069687 (MAPK8)
   04310 Wnt signaling pathway
    129069687 (MAPK8)
   04668 TNF signaling pathway
    129069687 (MAPK8)
   04068 FoxO signaling pathway
    129069687 (MAPK8)
   04071 Sphingolipid signaling pathway
    129069687 (MAPK8)
   04024 cAMP signaling pathway
    129069687 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    129069687 (MAPK8)
   04137 Mitophagy - animal
    129069687 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    129069687 (MAPK8)
   04215 Apoptosis - multiple species
    129069687 (MAPK8)
   04217 Necroptosis
    129069687 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129069687 (MAPK8)
   04530 Tight junction
    129069687 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129069687 (MAPK8)
   04621 NOD-like receptor signaling pathway
    129069687 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    129069687 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    129069687 (MAPK8)
   04660 T cell receptor signaling pathway
    129069687 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    129069687 (MAPK8)
   04659 Th17 cell differentiation
    129069687 (MAPK8)
   04657 IL-17 signaling pathway
    129069687 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    129069687 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129069687 (MAPK8)
   04920 Adipocytokine signaling pathway
    129069687 (MAPK8)
   04912 GnRH signaling pathway
    129069687 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    129069687 (MAPK8)
   04917 Prolactin signaling pathway
    129069687 (MAPK8)
   04926 Relaxin signaling pathway
    129069687 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    129069687 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    129069687 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    129069687 (MAPK8)
   04722 Neurotrophin signaling pathway
    129069687 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129069687 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129069687 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129069687 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    129069687 (MAPK8)
   05231 Choline metabolism in cancer
    129069687 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129069687 (MAPK8)
   05212 Pancreatic cancer
    129069687 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    129069687 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    129069687 (MAPK8)
   05161 Hepatitis B
    129069687 (MAPK8)
   05171 Coronavirus disease - COVID-19
    129069687 (MAPK8)
   05162 Measles
    129069687 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129069687 (MAPK8)
   05169 Epstein-Barr virus infection
    129069687 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129069687 (MAPK8)
   05135 Yersinia infection
    129069687 (MAPK8)
   05133 Pertussis
    129069687 (MAPK8)
   05152 Tuberculosis
    129069687 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129069687 (MAPK8)
   05142 Chagas disease
    129069687 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129069687 (MAPK8)
   05012 Parkinson disease
    129069687 (MAPK8)
   05016 Huntington disease
    129069687 (MAPK8)
   05017 Spinocerebellar ataxia
    129069687 (MAPK8)
   05020 Prion disease
    129069687 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    129069687 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129069687 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    129069687 (MAPK8)
   05415 Diabetic cardiomyopathy
    129069687 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    129069687 (MAPK8)
   04936 Alcoholic liver disease
    129069687 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    129069687 (MAPK8)
   04931 Insulin resistance
    129069687 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129069687 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129069687 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppam01001]
    129069687 (MAPK8)
Enzymes [BR:ppam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     129069687 (MAPK8)
Protein kinases [BR:ppam01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   129069687 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 129069687
NCBI-ProteinID: XP_054428358
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagtaagcgggacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgctgcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaaccaaactcatgctaagcgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttctgaatgtttttacaccacagaaatctttagaagaa
tttcaagatgtttacatagtcatggagcttatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagccaagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaagtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcaatggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
cctgccgattcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtcattgatgcatctaaaaggatctctgtagatgaagctcttcagcacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattaatatacaaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcttctgtcaatgatgtgtct
tcaatgtcaacagatccaactttggcctcggatacagacagcagtctagaagcctcagcg
ggacctctgggctgctgtagatga

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