Pteronotus mesoamericanus (Parnell's mustached bat): 129070029
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Entry
129070029 CDS
T09558
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam00562
Inositol phosphate metabolism
ppam01100
Metabolic pathways
ppam04014
Ras signaling pathway
ppam04015
Rap1 signaling pathway
ppam04020
Calcium signaling pathway
ppam04024
cAMP signaling pathway
ppam04070
Phosphatidylinositol signaling system
ppam04919
Thyroid hormone signaling pathway
ppam04933
AGE-RAGE signaling pathway in diabetic complications
ppam05205
Proteoglycans in cancer
Module
ppam_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129070029 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
129070029 (PLCE1)
04015 Rap1 signaling pathway
129070029 (PLCE1)
04020 Calcium signaling pathway
129070029 (PLCE1)
04070 Phosphatidylinositol signaling system
129070029 (PLCE1)
04024 cAMP signaling pathway
129070029 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
129070029 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
129070029 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129070029 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ppam04131
]
129070029 (PLCE1)
Enzymes [BR:
ppam01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129070029 (PLCE1)
Membrane trafficking [BR:
ppam04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129070029 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
129070029 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
129070029
NCBI-ProteinID:
XP_054428851
LinkDB
All DBs
Position
Unknown
AA seq
2300 aa
AA seq
DB search
MLVKMTSEEMAASVLVPVTQRKEMSPQSAVDESGEKVSDISVPKTHTVGQGGQTSHTSSK
LNKLKEESSGSNLPKILSIAREKIMSDENCNEKSWEKSMPGSVENLNINCKNVLENDLHG
LPQSQFYETCDSVTEKTGIPSSLERKVFPGIQLEIDEPSMAISPLGNQSAIIETSGAPPE
SNVEVFHFHYELDRRMPDTFCTLSDNLILDDCGNCVPLPDVGGEQKKNHMAYTCKLMQSA
KSCDNENRQLQCDHCDTLNDEYLCCERSCQEASVVHSSDSFFRENFMDDPSAKTFLSHFE
DFPGNCEDVEDLLKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLAAWS
YIDMKRSGLLLPCGREMGQLPTVLVRQDGSRYLSEAQWYSIYNAVRRGEETEDTIGSLLH
FFTKLPASETAHERINVGPCLKQCVRDTVCEYRATLQRTAISQYITGSLLEATTSLGARS
GLLSTFGGSTGRMMLKERQSGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILME
QEQSIYRKVLPVDYLCFLTQNLGTPEYQRSLPCLKASISASILNSHNGEHNALEDLVMRF
NEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKMWQ
FMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGAS
GLVKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSRSL
ETEEEDSASEGNSSRKNSLKDKARCQFIIGDLLDTENDIFEQPREWDPHGLEEPQKAFDH
GTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASP
ASAKAKLGVLSNTSEPGKFPLLGNTGLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNK
LSNMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQ
WLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSTEKPNMQRNNTLGI
STTKKKKKILMRGESGEATDDEMATRKAKMHKDCRSWSGSDPQDINEQEEPETNAITSPP
NSLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSNKSPSSAWSSSSWHGRIKGGMKG
FQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRLGSEPAALYTNLTIDE
NTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGIF
GVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFAS
KNDESQENSKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWD
GDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFK
TVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASM
QAQAYNGGNANPPPPNNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEE
IPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLST
LNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSNEGIRQAWEESSSPLSPT
TSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRTYPAATRIDSSNPNPL
MFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD
LDNMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNE
QFFFRVYFEDLVFLRFAVVENNSSAVTAQRILPLKALKRGYRHLQLRNLHNEVLEISSLF
INSRRMEENSSGSTVPASLMFNTEERKCFQTHRVTVHGVPGPEPFTVFSINGGTRAKQLL
QQILTIEQDTKPISTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILNSWFPEEG
YVGRIVLKTQQENLEEKSIVQDDKEVILASEEESFFVQVHDVSPEQPRTVIKAPRVSTAQ
DVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANKKSSTPKSSQRVLLDQECVFQAQ
SKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPRGLTSPTQVLTSESVQ
SKEEKPVGSLSSSDTTVYRQ
NT seq
6903 nt
NT seq
+upstream
nt +downstream
nt
atgttggtcaagatgacttctgaagaaatggcagcttctgttcttgtacctgtgactcag
agaaaagagatgtctcctcagtcagctgtagatgaaagtggtgaaaaggtctcggacatc
agtgttccaaagacacacacagttggacagggtgggcagacttctcataccagctcaaaa
ctgaacaaacttaaggaagaatcttctggaagcaacttgcctaagattctctcaatagca
agagagaaaataatgagtgatgagaactgtaatgaaaagtcctgggagaaaagcatgcca
ggttctgtggaaaaccttaatattaactgcaaaaatgtattggaaaatgatctgcatggt
cttcctcagagccagttttatgaaacatgtgattctgtcacagagaaaactggaattcct
tcttcactggaaagaaaagtgttccctggaattcaactggaaatagatgaaccttccatg
gccattagtcccttaggaaatcagtcagcaatcatagagacaagtggggcaccccctgag
agcaatgtggaggtatttcactttcattatgaacttgacagaagaatgccagatactttc
tgtactctatcagataacttgattctggatgattgtggaaactgtgttccactgcctgat
gttggtggggagcaaaagaaaaatcatatggcatatacttgtaaactaatgcaatcggca
aaaagctgtgataatgagaacaggcagctacagtgtgatcattgtgataccttgaatgat
gaatacttgtgctgcgaacgttcctgccaagaggccagtgtggtacattcaagcgacagc
tttttcagggagaattttatggatgatccatctgctaagacctttctgagccattttgaa
gacttccctggtaattgtgaagatgtagaagatctgttgaaaagtaaaaaggagcggtca
actttgctagtgagaagattttgtaaaaatgacagggaagttaagaaatctgtgtatact
ggaacaagggcaattgtgagaactctgccttctggtcacattggactggcagcttggagt
tacattgatatgaagagaagtggtctcttattgccttgtgggagagagatgggccagctg
ccaaccgtgctggttaggcaagatgggagccggtatttgtcagaagcccagtggtattcg
atctacaatgcagtgagaaggggagaagaaacagaagatacaattggatctcttctccat
ttcttcacaaagctcccagcctccgagacagcacatgagaggattaacgttggtccctgc
ttaaagcaatgtgtccgagacacagtatgtgagtatcgtgccaccctccaaagaacggcc
atatctcagtacatcaccggttctctcctagaagcaaccacatctttaggagcaagaagt
ggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgccaatca
ggtacctctatggccaattccagtgccctcccttcaagttcagctgggatcagcaaggaa
ctgattgatctgcagcccctcatccagtttcctgaggaagttgccagcatcctgatggag
caggagcagagtatttaccgaaaggtcttgccagttgactatctttgcttcttaacccag
aacttgggcactccggaatatcagaggtccctgccctgcctcaaagcatccatctcagca
tcaattcttaactcccataatggagaacacaatgctcttgaagatcttgtgatgagattt
aatgaggtgagttcctgggtgacgtggctgatcctcacggcaggctccatggaggagaag
cgggaagtcttctcatatttggtgcatgtggccaaatgctgttggaacatgggcaactac
aacactgtcatggagttcttggccggcctcaggtcaagaaaagttttaaagatgtggcag
tttatggaccagtctgacctggagaccatgaggagcctgaaggacgccatggctcagcac
gagtcttcctgcgagtacaggaaggtggtgacgcgggcgctgcacatccccggttgtaag
gtggttccattctgcggggtgtttctgaaggagctctgtgaagtactagatggagcctct
ggcctcgtgaagctctgcccaagatacaattcccaagaggaaactctagagtttgtagcc
gactacagtggacaagataattttttacaacgcgtgggacaaaatggcttaaagaattcg
gagaaagagtccaccgttaacagcatctttcaggtcatcaggagctgcagtcgaagtctg
gagacagaggaagaggacagcgccagtgaagggaacagctctaggaaaaactccttgaag
gataaagctcgatgccagtttataattggagatttgctggatacagaaaatgacatcttt
gagcagcccagagaatgggaccctcatggattagaagagccccagaaggcctttgaccat
gggacagagctcatcccatggtatgtcctgtccatccgagctgacgtgcaccagttcctg
ctgcagggggccacagttatccactatgaccaggacacacacctctcagcccgctgcttc
ctccagctccagcctgacaatagcaccttgacctggataaagcccaccactgcctcccca
gccagtgctaaagcaaaacttggtgtgcttagtaacacatctgaacctggcaaattcccg
ctattgggcaacactggattaagtggcctggtagaaggggtcttggatctgttttcagca
aaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaacaaa
ctaagtaacatgtttctctcagagacgggagtgacactgctctatgggcttcagaccact
gacaataggttattgcactttgtggcaccgaagcacacagctaagatgctcttcagcgga
ttgttggaactcactagagctgtgagaaagatgaggaagttccctgaccaaagacagcag
tggctgcggaaacagtatgtcagcctctaccaggaggatggacggtatgaaggcccaact
ttggctcacgctgtggagctatttggtggcagacggtggagtactcgaaatcccagccct
gggacatcagcaaagagtactgagaagcccaacatgcagaggaacaacaccttaggcatc
agcactaccaagaaaaagaagaaaatccttatgaggggggagagtggagaggcgactgac
gatgagatggccacacgaaaggccaaaatgcacaaagactgtcggagctggagtggttct
gatcctcaagacattaatgaacaagaagaaccagagacgaatgccatcacgagcccacct
aactccctcccttctagaagagcccactctctgaccacggctgggtctcctaacttggct
gccgggacatcatctcccatcaggccagtgtcctcccctgtgctgtcttcaaacaagagc
ccatccagtgcttggagcagcagcagctggcacgggcgcatcaaaggaggaatgaaaggc
tttcagagcttcatggtttcagacagtaacatgagttttgttgaatttgttgagctgttc
aaatccttcagtgtaaggagccgcaaggacctgaaggatctctttgacctctatgccgtg
ccctgcaaccgtttgggctctgagccggctgcactatatacgaacctaaccattgacgaa
aacaccagcggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttgggg
ttgttcattaaaagtaaacagcagctgtcagacaaccagaggcagatctctgacgccatt
gctgctgcaagtatcgtgacaaatggcaccggggtcgaaagcacatccctgggcatattt
ggggttggcatactccagctcaatgactttctagtgaattgccaaggagaacactgcact
tacgatgaaatcctcagcatcatccagaagtttgagcctagcattagtatgtgtcatcag
ggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagacaattttgcctca
aaaaacgatgagtcacaggaaaacagtaaagagttacagctgcccctgtcctactattac
attgaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagta
gaactctacagccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggat
ggagacgatggaatgcccatcatttaccatggacatacactgacaaccaagatccccttc
aaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgccaatcatc
atctcgattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaag
actgtgtttggagaaaaactggtggctaagttcttatttgagagtgatttctcagatgac
ccaatgcttccttcacctgaccaacttagaaggaaggtgcttcttaaaaataaaaagcta
aaagcacatcagacaccggtggatatcttaaagcaaaaggctcatcagttagcatccatg
caagctcaggcttataatggtgggaatgccaaccccccgcctcctaataacgaggaggag
gaagatgaagaggatgagtatgattatgactacgaatccctctctgacgacaacattcta
gaagatagacctgaaaataaatcatgtaacgacaagcttcagtttgaatacaatgaagaa
atccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtatatgac
atggaattgggagaagaattttatcttcctcagaataaaaaggagagcagacagattgca
cccgagctttctgaccttgtcatctattgccaagcagtaaaatttccaggcctgtcaact
ctaaatgcatctggctctagcaggggaaaagaaaggaaaagcaggaagtccatttttggc
aacaatccgggcagaatgagccctggggagacagcatcatttaacaaaacatctggaaaa
agttccaacgaaggaatacgacaggcctgggaggaatcttcttcccccctcagcccaacc
acatccctcagcgctatcattagaactcccaaatgttaccatatctcatcgttgaatgaa
aatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccacctgt
cagctgctcaggacttacccagctgccacccgcatcgactcgtccaaccccaaccccctc
atgttctggctgcatgggatacagcttgtggcactcaactaccagacagatgatctccct
ttacatttaaatgctgccatgtttgaggccaacggtggctgtggctatgttttgaagccc
ccagttctgtgggacaagaactgtcccatgtatcagaagttctctcccttggaaagagac
ctggacaacatggagcccgccgtctattctttaactattgtctctggccagaacgtgtgc
ccaagtaacagcacaggaagcccgtgcattgaggtcgatgtcctgggcatgccgctggac
agctgccacttccgcacaaagcccatccatcgaaacactctaaaccccatgtggaacgag
cagttcttcttccgggtttactttgaagaccttgtatttcttcgttttgcagtcgtggaa
aacaacagctcagcagtcactgctcagagaatccttccactcaaggctttaaaacgagga
tatcggcatctccagctgcgaaacctccacaatgaagtcctagaaatctctagtttattc
ataaacagcagaaggatggaagaaaattcctctggcagtactgtgccagcctctttgatg
tttaatacagaagaaagaaaatgttttcagactcacagagtcacagtacatggggtccca
ggtccagaaccctttactgttttctctataaatggaggcaccagggcaaagcagcttctc
caacaaattctgaccattgaacaagacaccaaacctatttccacagactattttttgatg
gaagaaaaatattttatctctaaagaaaagaatgaatgcagaaaacaaccattccagaga
gccattggtccagaagaagagattgtgcagattttaaacagctggtttccagaggaggga
tacgttggcaggattgtgttaaaaacccagcaggaaaacctagaagagaaaagcattgtt
caagatgacaaagaggtgatcttggcctcagaggaggagagtttctttgtccaggtgcat
gacgtgtccccggagcagcctcgaaccgtcatcaaagcgccccgcgtcagcaccgcgcag
gatgtcattcagcagaccttatgcaaagccaagtactcctatagcatcctgagcaacccc
aacccgagtgactatgtccttttggaagaggtggtgaaagacacagccaacaagaaatct
tccacccccaagtcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcccaa
agcaagtggaaaggcgcaggaaaattcatccttaaactaaaggagcaggtgcaggcatcc
cgagaagacaaaagaaaaggcatttcttttgcaagtgaattcaagaagttcaccaaatca
actaaacagccccggggactcacatcacccactcaggtcttgacctcagaaagtgtccaa
agcaaggaggagaaacctgtaggcagcttgtcctccagtgacacgacagtctatcgacag
tga
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integrated database retrieval system
