Pteronotus mesoamericanus (Parnell's mustached bat): 129070208
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Entry
129070208 CDS
T09558
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam04140
Autophagy - animal
ppam04141
Protein processing in endoplasmic reticulum
ppam04210
Apoptosis
ppam04932
Non-alcoholic fatty liver disease
ppam05010
Alzheimer disease
ppam05012
Parkinson disease
ppam05014
Amyotrophic lateral sclerosis
ppam05016
Huntington disease
ppam05017
Spinocerebellar ataxia
ppam05022
Pathways of neurodegeneration - multiple diseases
ppam05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
129070208 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129070208 (ERN1)
09143 Cell growth and death
04210 Apoptosis
129070208 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
129070208 (ERN1)
05012 Parkinson disease
129070208 (ERN1)
05014 Amyotrophic lateral sclerosis
129070208 (ERN1)
05016 Huntington disease
129070208 (ERN1)
05017 Spinocerebellar ataxia
129070208 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
129070208 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129070208 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
129070208 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129070208 (ERN1)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129070208 (ERN1)
Protein kinases [BR:
ppam01001
]
Serine/threonine kinases: Other
IRE family
129070208 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
129070208
NCBI-ProteinID:
XP_054429000
LinkDB
All DBs
Position
Unknown
AA seq
975 aa
AA seq
DB search
MPARLLLLLLAFLLSGPRIFARASTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF
DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFNPGLKGKNKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVIHLVDQNSGNAPTTISQ
DVEEKFAHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHRQFQ
KELEKIQLLQQQQLPFHTPADVAQDAELLDSSGLYSESSGASSPSTSPRASNHSLYSSGS
ASRTGASPSPEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGKIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKLDWRENITVPLQTDLRKFRSYKGGSVRDLLR
AMRNKKHHYRELPVEVRETLGALPEDFVRYFTSRFPHLLSHTYRAMELCSQERLFQPYYF
YLAPEPQPPRTPDTL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctactgctgctggcgtttctgctgtccggccccaggattttt
gcaagggccagcacagtgacgcttcctgaaaccttgctgtttgtctcaaccctggatgga
agtttgcatgctgtgagcaagaggacaggctccatcaaatggactttaaaagaagatcca
gttctgcaggttccaacacatgttgaagagcctgccttcctcccagaccccaatgacggc
agcctgtacacacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatc
ccggagttggtacaggcatccccgtgccgaagttcagatggaattctctacatgggtaaa
aagcaggacatttggtatgtcattgaccttctgaccggagagaagcaacagaccttgtcc
tcggcctttgctgatagcctctgcccgtcgacctctcttctgtaccttgggcgaacagaa
tacaccatcaccatgtatgacaccaagacccgagagctccggtggaatgccacttacttc
gactacgcagcctcgctgcccgaggacgacgtggactacaagatgtcccactttgtatcc
aatggcgacgggctggtggtgactgtggacagtgaatctggtgacgtcctgtggatccag
aactatgcttcccctgtggtggccttctatgtctggcagcgggagggtctgaggaaggtg
atgcacatcaacgtcgcggtggagaccctgcgctatctgaccttcatgtccggggaggtg
ggccgcatcaccaagtggaagtaccccttccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgttgggaaatactctactagcctctatgcctccccctcaatggtg
catgagggtgttgccgttgtgccccgagggagcactcttcctttactggagggtccccag
acagacggtgtcaccattggggacaaaggggagtgtgtgatcacacccagcacagaccta
aagtttaaccctgggctcaaaggaaagaacaagctcaactacttgaggaactactggctt
ctgattgggcaccatgaaaccccgttgtctgcgtcgaccaagatgctggagagattcccc
aacaatctgcccaaacacagggaaaatgtcattcctgctgactcagagaaaaagagcttt
gaggaagttatccacctggttgatcagaattcagggaatgcgcctaccaccatctctcag
gatgtggaagaaaagtttgctcatgcccccgccaagcccgaggcccccgtggactccatg
ctcaaggacatagccaccatcatcctgagtaccttcctgctcatcggctgggtggccttc
atcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccggcagttccag
aaggaactggagaaaatccagctcctgcagcagcagcagctgcccttccacacacctgcg
gacgtggctcaggacgccgagctcctggactcgtctggcctgtactcggagagctcgggc
gccagcagccccagcacgtcccccagagcctccaaccactcgctctactccagcggctct
gcctccaggactggcgccagcccctccccagagcaggatgacgaggacgaggaaaccagc
atggtgatggttgggaaaatctcattctgtcccaaggacgtcctaggccacggagccgaa
ggcaccattgtgtaccggggcatgttcgacaaccgtgacgtggcagtcaagaggatcctc
cccgagtgcttcagtttcgccgaccgcgaggtccagctgctgcgggaatctgacgagcac
ccaaatgtgatccgttacttctgcaccgagagggaccggcagttccagtacattgccatt
gagctatgcgcagccacgctgcaggagtacgtggagcagaaggacttcgcccaccttggc
ctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctgcactccctc
aacattgtccacagagacctgaagccccacaacatcctcctctccatgcccaatgcgcat
ggcaagatcaaggccatgatctccgactttggcctctgcaagaagctggcagtgggcagg
cacagcttcagccgccgttcgggggtgcctggcacggaaggctggatcgctccggagatg
ctgagtgaggactgcaaggagaaccccacctacacagtggacatcttctctgcgggctgc
gtcttttactacgtgatatctgagggcagccaccctttcggcaagtccctgcagcggcag
gccaacatcctcctgggcgcctacagcctcgactgcttacaccctgagaagcacgaagat
gtcattgcccgggagttaatagagaagatgatcgcaatggatcctcagaagcgcccatca
gccaagcatgtgctgaaacaccccttcttctggagcctggagaagcagctccaattcttt
caggacgtgagtgaccgaatagaaaaggaatccctggatggcccaatcgtgaagcagctg
gagagaggtgggagagcggtggtgaaattggactggcgggagaacatcaccgtccccttg
cagacagacctgcgtaaattcagaagctataaaggtggctccgtcagagatctcctccgg
gccatgagaaataagaagcaccactaccgggagctccctgtggaggtgcgggagaccctg
ggcgccctccccgaagacttcgtgcgctacttcacgtcgcgcttcccccatcttctctcc
cacacctaccgggccatggagctatgcagccaagagaggctcttccagccctactacttc
tacctggccccggagcctcagccccccaggactccagacaccctctga
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integrated database retrieval system
