KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129070245
Entry
129070245         CDS       T09558                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam04010  MAPK signaling pathway
ppam04015  Rap1 signaling pathway
ppam04218  Cellular senescence
ppam04380  Osteoclast differentiation
ppam04620  Toll-like receptor signaling pathway
ppam04664  Fc epsilon RI signaling pathway
ppam04668  TNF signaling pathway
ppam04750  Inflammatory mediator regulation of TRP channels
ppam04912  GnRH signaling pathway
ppam04935  Growth hormone synthesis, secretion and action
ppam04936  Alcoholic liver disease
ppam05014  Amyotrophic lateral sclerosis
ppam05022  Pathways of neurodegeneration - multiple diseases
ppam05132  Salmonella infection
ppam05135  Yersinia infection
ppam05145  Toxoplasmosis
ppam05161  Hepatitis B
ppam05163  Human cytomegalovirus infection
ppam05167  Kaposi sarcoma-associated herpesvirus infection
ppam05169  Epstein-Barr virus infection
ppam05170  Human immunodeficiency virus 1 infection
ppam05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppam05417  Lipid and atherosclerosis
ppam05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129070245 (MAP2K6)
   04015 Rap1 signaling pathway
    129070245 (MAP2K6)
   04668 TNF signaling pathway
    129070245 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    129070245 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129070245 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    129070245 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    129070245 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    129070245 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129070245 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129070245 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    129070245 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    129070245 (MAP2K6)
   05161 Hepatitis B
    129070245 (MAP2K6)
   05163 Human cytomegalovirus infection
    129070245 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129070245 (MAP2K6)
   05169 Epstein-Barr virus infection
    129070245 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129070245 (MAP2K6)
   05135 Yersinia infection
    129070245 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129070245 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    129070245 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    129070245 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129070245 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    129070245 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    129070245 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppam01001]
    129070245 (MAP2K6)
Enzymes [BR:ppam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     129070245 (MAP2K6)
Protein kinases [BR:ppam01001]
 Serine/threonine kinases: STE group
  STE7 family
   129070245 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 129070245
NCBI-ProteinID: XP_054429078
LinkDB
Position
Unknown
AA seq 340 aa
MLVHCFTNNLLGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLE
PIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVT
FYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLS
VIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGY
SVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQC
LKKNSKERPTYPELMQHPFFTLHESKATDVASFVKQIIGD
NT seq 1023 nt   +upstreamnt  +downstreamnt
atgttagttcattgcttcactaataacctgctaggcaagaagcgaaaccctggccttaaa
attccaaaagaagcatttgaacaacctcagaccagttccacgccacctcgagatttagac
tccaaagcatgcatttctattggaaaccagaatttcgaggtgaaagcagatgacctggag
cctatagtggaactgggacgaggtgcatatggggtggtggagaagatgaggcacgtgccc
agcgggcagatcatggcagtgaagcggatccgggccacagtaaacagccaggagcagaaa
aggctactgatggatctggatatttccatgaggacagtggactgtccttttacggtcacc
ttttatggtgcactcttccgggagggtgatgtttggatctgcatggagctcatggataca
tcactagataaattctacaaacaagtgattgataagggccaaactattccagaggacatc
ttagggaaaatagcagtttctattgtaaaagcattagaacatttacacagtaagctctcc
gtcattcatcgagacgtcaagccctccaatgtgctgatcaataccttgggccaagtgaag
atgtgcgattttggaatcagtggctaccttgtagactccgttgcaaaaactattgacgca
gggtgcaagccgtacatggctcctgaaagaataaatccagagctcaaccagaagggatac
agcgtgaagtctgacatttggagtctgggcatcacaatgattgagttggccatccttcgg
tttccctatgactcgtgggggactcctttccagcagctcaaacaggtggtagaggagccg
tcaccgcagctcccagcagacaagttctctgaagagtttgtggactttacctcacagtgc
ttgaagaagaattccaaagaacggccaacatatccagagcttatgcaacatccatttttc
accctacacgaatccaaagcaacagatgtggcatcttttgtaaaacagattattggagac
taa

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