Pteronotus mesoamericanus (Parnell's mustached bat): 129071023
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Entry
129071023 CDS
T09558
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam04151
PI3K-Akt signaling pathway
ppam04217
Necroptosis
ppam04380
Osteoclast differentiation
ppam04550
Signaling pathways regulating pluripotency of stem cells
ppam04620
Toll-like receptor signaling pathway
ppam04621
NOD-like receptor signaling pathway
ppam04630
JAK-STAT signaling pathway
ppam04658
Th1 and Th2 cell differentiation
ppam04659
Th17 cell differentiation
ppam05140
Leishmaniasis
ppam05145
Toxoplasmosis
ppam05152
Tuberculosis
ppam05160
Hepatitis C
ppam05161
Hepatitis B
ppam05162
Measles
ppam05163
Human cytomegalovirus infection
ppam05164
Influenza A
ppam05165
Human papillomavirus infection
ppam05166
Human T-cell leukemia virus 1 infection
ppam05167
Kaposi sarcoma-associated herpesvirus infection
ppam05168
Herpes simplex virus 1 infection
ppam05169
Epstein-Barr virus infection
ppam05171
Coronavirus disease
ppam05200
Pathways in cancer
ppam05203
Viral carcinogenesis
ppam05212
Pancreatic cancer
ppam05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129071023 (JAK1)
04151 PI3K-Akt signaling pathway
129071023 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
129071023 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
129071023 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
129071023 (JAK1)
04621 NOD-like receptor signaling pathway
129071023 (JAK1)
04658 Th1 and Th2 cell differentiation
129071023 (JAK1)
04659 Th17 cell differentiation
129071023 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
129071023 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129071023 (JAK1)
05203 Viral carcinogenesis
129071023 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129071023 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
129071023 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
129071023 (JAK1)
05161 Hepatitis B
129071023 (JAK1)
05160 Hepatitis C
129071023 (JAK1)
05171 Coronavirus disease
129071023 (JAK1)
05164 Influenza A
129071023 (JAK1)
05162 Measles
129071023 (JAK1)
05168 Herpes simplex virus 1 infection
129071023 (JAK1)
05163 Human cytomegalovirus infection
129071023 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
129071023 (JAK1)
05169 Epstein-Barr virus infection
129071023 (JAK1)
05165 Human papillomavirus infection
129071023 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
129071023 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129071023 (JAK1)
05140 Leishmaniasis
129071023 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129071023 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129071023 (JAK1)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129071023 (JAK1)
Protein kinases [BR:
ppam01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129071023 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
129071023
NCBI-ProteinID:
XP_054430159
LinkDB
All DBs
Position
Unknown
AA seq
1152 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNQEVPEPGVEVLFYLSDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNHTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIRE
EWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH
YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTC
FEKPEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGELMSHLKKQILRTDNISFVLKR
CCQPKPREISNLLVATKKAQEWQPVYTMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGTL
VDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE
NIMVEEFVEGGPLDLFMHRKSEVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL
AREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT
LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPSQRPFFRAIM
RDINKLEEQNPDIVSEKQPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG
EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG
SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF
GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDS
SPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSNRTTF
QNLIEGFEALLK
NT seq
3459 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagaccgaggtgaatcaggaggtccctgagccaggggtagaagtgctcttc
tacctgtcagacagggagcccctccggctgggcagcggagagtacacggcggaggagctg
tgcatcagggcggcacaggagtgctgtatctctcctctgtgtcacaacctctttgccctg
tatgatgagaacaccaagctctggtatgctccaaatcacaccatcactgtagatgataag
acatcgctccggctccattacaggatgagattttactttaccaactggcacgggacaaat
gataatgagcagtcggtatggcgacattctccaaagaagcaaaaaaatggctacgagaaa
aaaaaagttcctgatgcaacccctctccttgacgccagctccctggaatatctgtttgct
cagggacagtacgatttggtcaaatgcctggcccccattcgagaccccaagacagagcag
gatgggcatgacatcgagaacgagtgtctggggatggccgtcctcgccatctcccattat
gccatgatgaagaagatgcagctgccagaactccccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttcttaccaggatgcggata
aataatgttttcaaggatttcctgaaggaatttaacaacaagaccatatgtgacagcagt
gtgtccacacatgacctgaaggtgaaatacctggccaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaatgacagcgggaatgttctctatgaggtgatggtgaccggaaatctt
ggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaattg
aaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgggaa
gagtggaacaatttttcttactttcctgaaatcactcacattgtaatcaaggagtctgtg
gtcagcattaataagcaagacaacaaaaaaatggaactgaagctctcttcccatgaggaa
gccttgtcctttgtgtccctggtagatggctacttccggctcacagcagatgcccatcat
tacctctgcaccgacgtggctcccccgttgattgtccacaacatacagaatggctgtcat
ggtccaatctgcacagaatatgccatcaataaattacggcaagagggaagtgaggagggg
atgtatgttctgcgatggagctgcactgactttgacaacatcctcatgacggtcacctgc
tttgaaaaacctgaggtgctgggtggccagaaacagttcaagaattttcagattgaggtg
cagaagggtcgctacagcctgcacggctcagaccgcagcttccccagcctgggggagctc
atgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaagcgc
tgctgccagcccaagccccgagaaatctccaatctgctcgtggctactaagaaagcccaa
gaatggcagcctgtttacactatgagtcagctgagtttcgatcggatcctcaagaaagac
attatgcaaggagagcaccttgggagaggcacgcggacacacatctactctgggaccctg
gtggattacaaggatgacgaaggaacttctgaagagaagaaaataaaagtgatcctgaaa
gtcttagaccccagccacagagacatttctctggccttcttcgaggcagccagcatgatg
agacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtggag
aatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccggaag
agtgaagtcctcaccacaccatggaaattcaaagttgccaaacagctggccagtgccctg
agttacctggaggacaaagacctggtccacggaaacgtgtgcacgaaaaacctcctcctg
gcccgcgagggcatcgacagcgagtgcggcccgttcatcaagctcagtgaccctggcatc
cccatcactgtgctgtccaggcaagaatgcatagaacgaatcccgtggattgctcccgag
tgtgtcgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaaccaca
ctctgggaaatctgctacaatggcgagatccccctgaaagacaagacactgattgagaaa
gagcgattctacgaaagccggtgcagaccagtgacaccatcttgtaaggagctggctgac
cttatgactcgctgcatgaactatgaccccagtcagaggccctttttccgagccatcatg
agagacatcaataagctggaagagcagaatccagacattgtttcagaaaagcagccagcc
accgaggtggatcccacacattttgaaaagcggttcttaaaaaggatccgtgacttggga
gagggccactttgggaaggttgagctctgccggtatgaccctgaaggggacaatacaggg
gagcaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagctgatctg
aagaaggaaatcgaaatcttaaggaacctgtatcatgaaaacattgtgaagtacaaaggc
atctgcacagaagatggaggaaatggtattaagcttatcatggaatttctgccttctgga
agccttaaggaataccttccaaagaataagaacaaaattaacctcaaacagcagttaaaa
tatgccgttcaaatttgtaaggggatggactatttgggttcacgacagtatgttcaccgg
gacttagcagcaagaaatgtccttgttgagagtgagcaccaagtgaaaattggagacttt
ggtttaaccaaagcaattgaaaccgacaaggaatactacacagtcaaggatgaccgcgac
agccctgtgttttggtatgccccagaatgcttaattcagtgtaagttttacatcgcctct
gacgtctggtctttcggagtgactctgcacgagctgctcacctactgtgattcagactcc
agccccatggcgttgttcctgaaaatgataggccccactcatggccagatgacagtaaca
agacttgtgaacacattgaaagaaggaaaacgtttgccctgtccacctaactgtccagaa
gaggtttatcaacttatgagaaaatgctgggaattccaaccatctaatcggacaaccttt
cagaaccttattgaaggatttgaagcacttttaaaataa
DBGET
integrated database retrieval system
