Pteronotus mesoamericanus (Parnell's mustached bat): 129075160
Help
Entry
129075160 CDS
T09558
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam00562
Inositol phosphate metabolism
ppam01100
Metabolic pathways
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam04012
ErbB signaling pathway
ppam04014
Ras signaling pathway
ppam04020
Calcium signaling pathway
ppam04062
Chemokine signaling pathway
ppam04064
NF-kappa B signaling pathway
ppam04066
HIF-1 signaling pathway
ppam04070
Phosphatidylinositol signaling system
ppam04072
Phospholipase D signaling pathway
ppam04360
Axon guidance
ppam04370
VEGF signaling pathway
ppam04380
Osteoclast differentiation
ppam04611
Platelet activation
ppam04613
Neutrophil extracellular trap formation
ppam04625
C-type lectin receptor signaling pathway
ppam04650
Natural killer cell mediated cytotoxicity
ppam04662
B cell receptor signaling pathway
ppam04664
Fc epsilon RI signaling pathway
ppam04666
Fc gamma R-mediated phagocytosis
ppam04670
Leukocyte transendothelial migration
ppam04722
Neurotrophin signaling pathway
ppam04750
Inflammatory mediator regulation of TRP channels
ppam04919
Thyroid hormone signaling pathway
ppam04933
AGE-RAGE signaling pathway in diabetic complications
ppam04935
Growth hormone synthesis, secretion and action
ppam05167
Kaposi sarcoma-associated herpesvirus infection
ppam05169
Epstein-Barr virus infection
ppam05170
Human immunodeficiency virus 1 infection
ppam05171
Coronavirus disease - COVID-19
ppam05200
Pathways in cancer
ppam05205
Proteoglycans in cancer
ppam05206
MicroRNAs in cancer
ppam05214
Glioma
ppam05223
Non-small cell lung cancer
ppam05225
Hepatocellular carcinoma
Module
ppam_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129075160 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
129075160 (PLCG2)
04064 NF-kappa B signaling pathway
129075160 (PLCG2)
04066 HIF-1 signaling pathway
129075160 (PLCG2)
04070 Phosphatidylinositol signaling system
129075160 (PLCG2)
04072 Phospholipase D signaling pathway
129075160 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129075160 (PLCG2)
04613 Neutrophil extracellular trap formation
129075160 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
129075160 (PLCG2)
04662 B cell receptor signaling pathway
129075160 (PLCG2)
04664 Fc epsilon RI signaling pathway
129075160 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
129075160 (PLCG2)
04670 Leukocyte transendothelial migration
129075160 (PLCG2)
04062 Chemokine signaling pathway
129075160 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
129075160 (PLCG2)
04919 Thyroid hormone signaling pathway
129075160 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
129075160 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
129075160 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
129075160 (PLCG2)
04380 Osteoclast differentiation
129075160 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129075160 (PLCG2)
05206 MicroRNAs in cancer
129075160 (PLCG2)
05205 Proteoglycans in cancer
129075160 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129075160 (PLCG2)
05214 Glioma
129075160 (PLCG2)
05223 Non-small cell lung cancer
129075160 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129075160 (PLCG2)
05171 Coronavirus disease - COVID-19
129075160 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
129075160 (PLCG2)
05169 Epstein-Barr virus infection
129075160 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129075160 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129075160 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ppam04131
]
129075160 (PLCG2)
Enzymes [BR:
ppam01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129075160 (PLCG2)
Membrane trafficking [BR:
ppam04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129075160 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
129075160 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
PH
SH3_9
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
129075160
NCBI-ProteinID:
XP_054435110
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTAMVNVDALQEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIVEIKEIRPGKNSKDFERAKVVRQKEDCCFTILYGTQFTLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQEHWAQDLNKVRKRMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCGVEQQRYMARV
FKEVFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDIDVDMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEELPQDTPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCSETGGKDGTFLVRESERFPNDYTLSFWRSGRVQHCRIRSTMEDGVLRYY
LTDNLTFPSIYDLIQHYRGTHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRAKGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
RKHALYRKMKLRYPVTPELLERYSMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTVDVEDLEKQII
EDNPLGSLCRGILDLNAYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIRQITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVIRQKPIDLLKYNQKALTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPLPLESQRKIQMTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALIKEFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccatggtcaatgtggacgcccttcaggaatatgagaagagtcagatcaaaaga
gccttggagctgggcacggtgatgactgtgttcagcttccgcaagtccaccccggagcgc
aggaccgtccaggtgatcatggagacgcggcaggtggcctggagtaagacagccgacaag
atcgaaggcttcttggatatcgtggaaataaaggaaatccgcccagggaagaactctaag
gattttgagcgtgctaaagtagtccgccagaaggaagactgctgcttcaccatcttgtat
ggcacccagttcaccctcagcacactcagtttagcagcggactctaaggaagatgcaacc
aagtggctctctggcttgaaaatcttacaccaagaagcaatgagcgcatccacacccacc
attattgagagttggctgagaaagcagatttattcagtggatcaaaccagaagaaacagc
atcagcctccgagagttgaaggccatcttgcccctcgtcaacttcaaagtgagcagtgcc
aagttcctcaaggataagtttgtggaaataggcgcgcacaaagatgaactcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaacagcaaaaatcgattcttgatgaa
ttcaaaaaagactcctctgtgttcatcctgggcaacactgaccggccggacgcctctgct
gttcacctgcacgacttccagcggtttctcttacatgaacagcaggaacattgggctcag
gatctgaacaaagtccgcaagaggatgacaaagtttatcgatgacacgatgagggaaact
gcggagcccttcttgtttgtcgatgagttcctcacatacctgttttcacgggagaacagc
atttgggatgagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcatcacataacacgtacctcacaggtgaccagctgcggagtgagtca
tccacggaggcatatatccgctgtctgcgcatgggctgtcgctgcattgagttggactgc
tgggacgggcccgacgggaagcccatcatctaccatggctggacacggaccaccaagatc
aagtttgatgatgttgtgcaggccatcaaagaccatgcctttgtcacctcgagcttccct
gtgatcctgtccatcgaggagcactgcggcgtggaacagcagcgctacatggccagagtg
tttaaggaggtgtttggcgacctgctgctgatgaagcccacggaggccagtgccgaccag
ctgccctcgcccagccagttgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggcgacatcgacgtcgacatggaggacaagaaggacgaacacaagcagcagggcgaa
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgcgccatcgccgat
gccaagttgtccttcagcgatgacattgaacagaccatggaagaggaactgccccaggat
acgcccccaacagagctgcattttggagagaagtggttccataagaaggtagagaagagg
acaagtgctgagaagctgttgcaggagtactgctctgagacagggggcaaggatggaacc
ttcttggtgcgggagagcgagagattccccaatgactacaccctgtccttctggcggtct
ggccgggtccagcactgccggatccgctctaccatggaggacggggtgctgcggtactac
ctgactgacaacctcacgttccccagcatctacgacctcatccagcactaccgtgggacg
cacctgcgctgcgccgagttcgagctccggctcaccgaccccgtgcccaaccccaacccc
cacgaatcaaagccgtggtactatgacgggctgagccgtggagaagcagaggacatgctc
atgagagttccccgggacggcgccttcctcatccggaagcgggaaggcagcgactcctac
gccatcaccttcagggccaagggcaaggtgaagcactgtcgcatcaaccgggacggccgg
cactttgtgctggggacctctgcctactttgagagtctggtggagctcgtcagttactac
aggaagcacgcgctgtaccgaaagatgaaactgcgctaccctgtgactcccgaactcctg
gagcgctacagtatggaaagagatataaactccctgtatgacgtcagcagaatgtatgtg
gatcccagtgaaatcaatccttctatgcctcagagaactgtgaaagctctatatgactac
aaagccaagcagagtgacgagctgagcttctgccgtggcgccctcattcacaacgtctcc
aaggagcccgggggctggtggaaaggagactatggaaccagaatccagcagtatttccca
tccaattacgttgaagacatttcaacagttgatgtggaggatctggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaatgcctataacgtt
gtgaaagcgccacagggcaaaaaccagaagccttttgtctttatcctggagcccaagaag
cagggtgaccctccagtggagtttgccacggacagggtggaggagctctttgaatggttt
cagagcatccggcagatcacctggaagattgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtcgatcgccatcgagctctcagacctggtcgtctactgcaaaccaacc
agcaagaccaaagacaacttagaaaatcccgacttccgagaaatccgttcctttgtggag
acgaaggctgacagcgtcatcagacagaaacccatcgatctcctgaagtacaatcagaaa
gccctgacccgtgtttacccaaaggggcagagggtggactcctccaactacgatcccttc
cgcctctggctgtgcggctcccaaatggtggcactcaatttccagactgcagacaaatac
atgcagatgaatcaggccttgttctccctcaatgggaggaccggctacgtcctacagccc
gagagcatgaggacggagaagtacgaccccctgccactcgagtcccagaggaagattcag
atgaccctgacggtcaaggttctcggggctcgccatcttcccaagcctggacgaagcatt
gcgtgtccctttgtggaggtagaaatatgtggagccgaatatgacaataacaagtttaag
acaacggttgtgaatgacaatggcctaagccctgtttgggcttcgacacaggagaaggtg
acttttgaaatctatgatccaaacctcgcatttctgcgctttgtggtgtatgaggaagat
atgttcagcgatcccaactttctcgctcatgctacttaccccattaaaggaatcaaatca
ggatttagatctgttcctctgaagaatgggtacagcgaagacatcgagctggcttccctc
ctggttttctgtgagatgcggccagtcctggagagcgaagaggaactgtactcctcctgt
cgccagctgcggaggcggcaagaagagctgaacaaccagctctttctatatgacacacac
cagaacttgcgcaatgccaaccgggatgccctcattaaagagttcaatgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccggaggttgagagagaagagagtcagcaac
agcaagttttactcatag
DBGET
integrated database retrieval system
