Pteronotus mesoamericanus (Parnell's mustached bat): 129077631
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Entry
129077631 CDS
T09558
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam04010
MAPK signaling pathway
ppam04014
Ras signaling pathway
ppam04015
Rap1 signaling pathway
ppam04020
Calcium signaling pathway
ppam04072
Phospholipase D signaling pathway
ppam04144
Endocytosis
ppam04151
PI3K-Akt signaling pathway
ppam04510
Focal adhesion
ppam04540
Gap junction
ppam04630
JAK-STAT signaling pathway
ppam04810
Regulation of actin cytoskeleton
ppam05163
Human cytomegalovirus infection
ppam05200
Pathways in cancer
ppam05206
MicroRNAs in cancer
ppam05214
Glioma
ppam05215
Prostate cancer
ppam05218
Melanoma
ppam05230
Central carbon metabolism in cancer
ppam05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129077631 (PDGFRA)
04014 Ras signaling pathway
129077631 (PDGFRA)
04015 Rap1 signaling pathway
129077631 (PDGFRA)
04630 JAK-STAT signaling pathway
129077631 (PDGFRA)
04020 Calcium signaling pathway
129077631 (PDGFRA)
04072 Phospholipase D signaling pathway
129077631 (PDGFRA)
04151 PI3K-Akt signaling pathway
129077631 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129077631 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129077631 (PDGFRA)
04540 Gap junction
129077631 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129077631 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129077631 (PDGFRA)
05206 MicroRNAs in cancer
129077631 (PDGFRA)
05230 Central carbon metabolism in cancer
129077631 (PDGFRA)
05231 Choline metabolism in cancer
129077631 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
129077631 (PDGFRA)
05218 Melanoma
129077631 (PDGFRA)
05215 Prostate cancer
129077631 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
129077631 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129077631 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129077631 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ppam04090
]
129077631 (PDGFRA)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129077631 (PDGFRA)
Protein kinases [BR:
ppam01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
129077631 (PDGFRA)
CD molecules [BR:
ppam04090
]
Proteins
129077631 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_PDGFR_d4
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Ig_6
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
129077631
NCBI-ProteinID:
XP_054438135
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSHLAVLVLGSLLAGPSLIFCQLSLPSILPNENEKVVQLNSSFSLRCSGESEVSWLYP
ISEDKKANVTIRNEENNSGLFVKVLEVANASAAHTGLYTCYYNHTQTEENEIEGSHIYIY
VPDPDVAFVPLGMTDYLVIVENDDFAIIPCRTTDPQTPVTLLNRDEVVLAAYDSRQGFNG
SFTGGPYICEAIVRGKKFHTIPFNIYALKATSELDLELDAPKTVYKSGETIVLTCIVFNN
EVVDFQWTYPGEVKSKGGVMLEEIKDPSLKLVYTLMVPEATVKDSGDYECVARQATSEVK
EMKKVTISVHEKGFIEIKPYFSQLEAVNLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDMKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAAGTPLPDIEWMICKDIKKCNNETSWTVLASNISNIITEVRPLD
RSVVEGQVTFAKVEETIAVRCLAKNLLGVENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKLKKELDIFGLNPADESTRSY
VVLSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDSSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEIYEIMVKCWNSEPEKRPSFYHLREIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatctggcagtcctggtcctaggctctctccttgcagggccgagccta
attttctgccagctttcattaccctctatcctcccaaatgaaaatgaaaaggttgtgcag
ctgaattcatccttttctctgagatgctctggggagagtgaagtgtcctggctgtacccc
atatctgaggacaagaaggccaatgtgacaatcagaaatgaggagaacaacagcggcctt
tttgtgaaagtgctagaagtggccaacgcctcggcggctcacacggggttgtacacttgc
tattacaaccatacacagacagaggaaaatgagattgaaggcagtcacatttacatctac
gtgccagacccagatgtagccttcgtacctctaggaatgacagattatttagtcatcgtg
gagaacgatgattttgccatcataccttgtcgcacaactgatcctcagacgccagtaacc
ttactcaacagggatgaggtggtgctcgccgcctatgacagcagacagggctttaatgga
agcttcactggtgggccctatatctgcgaggccattgtcagagggaagaagttccacacc
attccatttaacatttatgctttaaaagcaacctcagaacttgatctagaattggatgct
cctaaaactgtatacaagtcaggggaaaccattgtgctcacgtgcatcgtctttaacaac
gaggtggtggactttcagtggacctaccctggagaagtgaaaagcaaaggcggcgtaatg
ctggaggaaatcaaggacccgtccctcaaattggtgtacactctgatggtccccgaggcc
acggtgaaagacagtggtgattatgaatgtgttgcccgccaggccaccagcgaggtcaaa
gaaatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaaccctac
ttcagccagttggaagctgtcaacctgcatgaagtcaaacattttgtggtggatgtgcag
gcctacccacctcccaggatatcctggctcaaagacaacctgactctgatcgaaaacctc
acagagatcaccactgacatcgaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagacagtggccattatactattgtagttcagaatgaagat
gacatgaagagctacacttttgaactcttaactcaagttccctcatctattctggacttg
gtcgatgaccaccatggctctacagggggacagaccgtgagatgcacagctgcggggaca
cctcttcctgatattgagtggatgatttgcaaggatatcaagaaatgtaataatgagact
tcatggacagttttggccagcaacatctcaaacatcatcacagaggtccgccccttggac
aggagtgtggtggagggccaggtgacattcgccaaagtggaggagaccattgccgtccga
tgtctggctaagaatctccttggggttgagaaccgagaactgaagctggtggcccccact
ctgcgttccgaactcacagtggcagctgcagtcctggtgcttttggtgattgtgataatc
tcactgattgtcctggttgtcatttggaaacagaaaccaaggtatgaaattcgctggaga
gtcattgaatcaatcagccccgatggacatgaatatatttatgtggacccaatgcagttg
ccttatgactcgagatgggagtttcccagagatggactagtgctgggtcgtatactggga
tctggtgcatttgggaaagtggttgaaggaactgcgtatggattaagccggtcccaacct
gtcatgaaagtagcagtgaagatgcttaaacccacagcccgatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgacccacctggggccgcatttaaacattgtaaacttg
ctgggagcctgcaccaagtcaggccccatttacatcatcactgagtactgtttctacggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgccacccagagaag
ctaaagaaagagctggacatctttggattaaacccagctgatgaaagcactcggagttac
gttgttttatcttttgaaaacaatggtgactacatggatatgaagcaagctgacaccacc
cagtatgtccccatgctggaaaggaaagaggtttctaaatattcggacatccagagatcg
ctgtatgaccgcccagcctcatataagaagaaatccatgttagactcagaagtcaaaaat
cttctttcggatgacagctcggaaggcctcactttgttggatttgttgagcttcacctat
caagttgctcgaggaatggagtttttggcttccaaaaattgtgtccaccgggacctggct
gctcgcaacgtcctcctggcacaagggaaaatcgtgaagatttgtgactttggcctagcc
agagacatcatgcatgattcaaactatgtgtcaaaaggcagcaccttcctgcccgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccacgttgagcgacgtctggtct
tacggcatcctgctctgggagatcttttccctcggtggcacaccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gccaccagtgaaatctacgagatcatggtgaaatgttggaacagtgagccagagaagaga
ccctccttttaccatctgagagagattgtggagaacctgctgcctggacaatataaaaag
agttatgagaagattcacctggatttcctgaagagcgaccatcccgctgtggctcgcatg
cgagtggatgctgacaatgcctacattggtgtcacctacaaaaatgaggaagacaagctg
aaggactgggagggtggcctggacgagcagaggctgagtgctgacagtggctacatcatc
cctctgcctgacattgaccctgttccggaggaggaagacctgggcaagaggaacagacac
agctcacagacctccgaggagagtgccattgagacaggttccagcagctctaccttcatc
aagagagaggatgagaccatcgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtggaggacagcttcctttaa
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