Pteronotus mesoamericanus (Parnell's mustached bat): 129078300
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Entry
129078300 CDS
T09558
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam04062
Chemokine signaling pathway
ppam04081
Hormone signaling
ppam04148
Efferocytosis
ppam04151
PI3K-Akt signaling pathway
ppam04217
Necroptosis
ppam04550
Signaling pathways regulating pluripotency of stem cells
ppam04630
JAK-STAT signaling pathway
ppam04658
Th1 and Th2 cell differentiation
ppam04659
Th17 cell differentiation
ppam04725
Cholinergic synapse
ppam04917
Prolactin signaling pathway
ppam04920
Adipocytokine signaling pathway
ppam04933
AGE-RAGE signaling pathway in diabetic complications
ppam04935
Growth hormone synthesis, secretion and action
ppam05140
Leishmaniasis
ppam05145
Toxoplasmosis
ppam05152
Tuberculosis
ppam05161
Hepatitis B
ppam05164
Influenza A
ppam05167
Kaposi sarcoma-associated herpesvirus infection
ppam05168
Herpes simplex virus 1 infection
ppam05200
Pathways in cancer
ppam05207
Chemical carcinogenesis - receptor activation
ppam05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ppam05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129078300 (JAK2)
04151 PI3K-Akt signaling pathway
129078300 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
129078300 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129078300 (JAK2)
09143 Cell growth and death
04217 Necroptosis
129078300 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
129078300 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
129078300 (JAK2)
04659 Th17 cell differentiation
129078300 (JAK2)
04062 Chemokine signaling pathway
129078300 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
129078300 (JAK2)
04917 Prolactin signaling pathway
129078300 (JAK2)
04935 Growth hormone synthesis, secretion and action
129078300 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
129078300 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129078300 (JAK2)
05207 Chemical carcinogenesis - receptor activation
129078300 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129078300 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
129078300 (JAK2)
05164 Influenza A
129078300 (JAK2)
05168 Herpes simplex virus 1 infection
129078300 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
129078300 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
129078300 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129078300 (JAK2)
05140 Leishmaniasis
129078300 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129078300 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129078300 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129078300 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129078300 (JAK2)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129078300 (JAK2)
Protein kinases [BR:
ppam01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129078300 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
129078300
NCBI-ProteinID:
XP_054439061
LinkDB
All DBs
Position
Unknown
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGVSTFPIHHNGDIPGIADPVKQIDPVLQVYLYHSLGKTEGDYLKFPTGEY
VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPY
WYCNGSNRTYRHGVSRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLGMA
VLDMMRIAKENDQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLETLQSAFYTEKFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPDIIDVSIKQANQEVSNESRIVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTADAHHYLCKEVASPMVLENIQSNCHGPISMDFAINKLKKAGNQTGL
YVLRCSPKEFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNCYQ
METVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLLRHNNVNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKTSINILWKLEVAKQLAWAMH
FLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLAIDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggagtatccacatttcctatacatcataat
ggtgatatccctggaattgctgaccctgtgaagcaaatagatccagtcctgcaggtgtat
ctttatcattcccttgggaaaactgagggagattacctgaagtttccaactggggagtat
gttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacaccagtgtatcac
agtatgtttgctttaatgagtgaaacagaaaggatctggtatcctcccaaccatgtcttc
catatagatgagtcaacaaggcacaatgtactctacagaataagattttactttccttac
tggtattgtaacggcagcaacagaacctatcggcatggagtatctcgaggtgctgaagcg
cctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgtcatgatttcttg
catggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggca
gtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactggacatctatagc
tctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagagtatcat
attttaacaagaaagcgaataaggtacagatttcgcagatttattgagcagttcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag
tctgccttctacacagagaaatttgaagtaaaagaacctggaagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatactgtgattttcctgat
attattgatgtcagtattaagcaggcaaaccaagaagtctcaaatgaaagcagaattgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagagaagct
ttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacatcattac
ctctgtaaagaagtggcatctccaatggtgcttgaaaatatacaaagcaactgtcatggc
ccaatttcaatggattttgccataaataaactgaagaaagcaggtaatcagactggactt
tatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgctgttgag
cgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatggagaatac
aacctcagtgggactaagaagaacttcaataatcttaaagatcttttgaattgttaccag
atggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtcccccaaag
ccaaaagataaatcaaaccttctagtcttcagaaccaatggtgtttctgatgtgccaacc
tcaccaacattactgaggcataataatgtgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatatttaacgaaagccttggccaaggcacttttacaaaaatttttaaaggt
gtaagaagagaaataggagactacggtcaacttcatgaaacagaagttcttttaaaagtt
ttggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtaaaatttggatcactagatacatatttgaaaaagaataaa
acttctataaatatattatggaaacttgaagtggctaaacagttggcatgggccatgcat
tttctagaagaaaaaacccttattcatgggaatgtgtgtgccaaaaatattctacttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcattgaaaatcctaaaaatttaaacttggcaatagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataagcccctgaatgctttggattctcagagaaag
ctacagttttatgaagatagacaccagcttcctgcaccaaagtggacagaattagcaaat
cttattaataattgtatggattatgaaccagattttagaccttctttcagagccatcata
cgagatctaaacagtttgtttactccagattatgaacttttaacagagaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcttttgaagacagagaccctact
cagtttgaagagagacacttgaaatttctgcagcagcttggcaagggtaattttgggagt
gtggagatgtgccggtacgaccctctacaagacaacactggggaggtggtggctgtgaaa
aagcttcagcacagcactgaagagcacctcagggactttgaaagggagattgaaatcctt
aaatccctgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgctggccgg
cgtaatctaagattaattatggaatatttaccatatggaagtttacgtgactatctccaa
aagcataaagaacggatagatcataaaaaacttctgcagtacacatctcaaatatgcaag
ggtatggagtatcttggtacaaaaaggtatatccacagggacctggcaacaaggaatata
ttggtggagaatgaaaacagagttaaaattggagattttggattaaccaaagtcttgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcctcggatgtttggagctttggagtg
gttctgtatgaacttttcacatatattgaaaagagtaaaagtccaccagcggaattcatg
cgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactcttg
aagaataacggaagattacctagacccgatggatgcccagatgagatttatgtgatcatg
acagaatgctggaacaataatgtaaatcaacgcccctctttcagacacctcgctcttcga
gttgatcaaataagggacaatatggctggatga
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integrated database retrieval system
