KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129079176
Entry
129079176         CDS       T09558                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
  KO
K02599  Notch 1
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01522  Endocrine resistance
ppam04330  Notch signaling pathway
ppam04658  Th1 and Th2 cell differentiation
ppam04919  Thyroid hormone signaling pathway
ppam05020  Prion disease
ppam05165  Human papillomavirus infection
ppam05200  Pathways in cancer
ppam05206  MicroRNAs in cancer
ppam05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    129079176 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    129079176 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    129079176 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129079176 (NOTCH1)
   05206 MicroRNAs in cancer
    129079176 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    129079176 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    129079176 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    129079176 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129079176 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank Notch NOD NODP Ank_4 Ank_5 Ank_3 EGF_3 EGF_Teneurin EGF_DL_JAG
Other DBs
NCBI-GeneID: 129079176
NCBI-ProteinID: XP_054440127
LinkDB
Position
Unknown
AA seq 2551 aa
MPPLLAPLLCLALLPALGARGLRCSQPSESCVNGGTCEVSANGTEACVCSQAFAGQRCQA
HSPCLSAPCKNGGTCHAVDRGGAVDYVCSCRLGFSGPLCLTPRDNPCLANPCRNGGTCDL
LTLTDYKCLCPPGWSGKMCQQADPCASNPCANGGRCLPFEATYICGCPPGFHGPTCRQDV
NECGQSPGPCRNGGTCFNEVGSYRCVCRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDT
THECACLPGFTGQNCEENIDDCPGNSCQNGGTCVDGVNTYNCRCPPEWTGQYCTQDMDEC
HLIPNACQNGGTCHNTLGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG
ANPCEHKGKCLNTLGSFQCRCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICM
PGYEGVYCEVNKDECASSPCLQNGRCLDKINEFQCECPPGFTGNLCQYDVDECASTPCKN
GAKCLDGPNTYSCVCTEGYTGPHCEVDIDECDPDPCHYGSCQDGVAAFTCLCQPGYTGHH
CETNINECYSQPCRHGGTCQDRDNAYLCLCLKGTTGPNCEINLDDCASSPCDAGTCLDKI
DGYECACEPGYTGSMCNINIDECASSPCHNGGTCEDGVNSFTCRCPEGYHDPTCLSEVNE
CNSNPCIHGACRDSLNGYKCDCDPGWSGANCDINNNECESNPCVNGGTCKDMTSGYVCTC
REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCASRPCR
NGGECKASEDYESFSCVCPVGWQGQTCEVDINECVKSPCRHGASCQNTNGGYRCHCQAGY
TGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCHHGAN
CTDCVASYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCE
HDINECDSRPCLHGGTCQDSYGTYKCTCPLGYTGLNCQNLVRWCDSSPCKNGGRCWQTNV
LYRCECHSGWTGLYCDVPSVSCEAAARQRDTNVTHLCRNGGLCVDAGNTHHCRCRPGYTG
SYCEDQVDECSPNPCQNGATCTDYPGGYSCECVAGYHGVNCSEEINECLSHPCQNGGTCI
DLANMYKCSCPRGTQGVHCEINMDDCNPPIDPVSRGPKCFNNGTCVDQVGGYSCTCLPGF
VGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRPGHTGRRCEAVINGCKGKPCKNG
GTCAVASNTPHGFICKCPAGFEGSTCENDARTCGSLRCLNGGTCISGPRSPTCLCLGTFT
GPECQFPASSPCVGGNLCYNQGTCEPVPENPYYRCLCPAKFNGLHCHILDYSFRGGVGLD
ITPPQIEEACELPECREEAGNKVCSLRCNNHACGWDGGDCSLNFNDPWQNCTQSLECWKY
FSNGHCDHQCNSAGCLFDGFDCQHTEGQCNPLYDQYCKDHFGDGHCDQGCNSAECEWDGL
DCADHVPERLAAGTLVVVVLMPPEQLRNHSFRFLRELSRLLHTNVVFKRDADGQQMIFPY
YGHEEELRKHPIKRSLDGWAAPGALLDQVKAALLPDGSGGRWRRELDPMDIRGSIVYLEI
DNRQCVQASAQCFHSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPPLHFMYVA
VAAFVLLFFVGCGVLLSRRRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNS
SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRVPAMAP
TPPQGEADADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
VEAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
AQERMHHDIVRLLDEYSLVRSPQLHGAALGGPPTLSPPLCSPSGCLGTLKPTVQGKKARK
PSTKGLAGGGKEARDLKARRKKSQDGKGCLLDSASVLSPVDSLESPHGYLSDVASPPLLP
SPFQHSPTVPLNHLPGMPDAHLGIGHLNVAAKPEMAALGGGGRLAFEAGPPRLSHLPVAS
GTGTVLGTSGGSGAVNFTVGATTGLNGQCEWLSRLQNGLVPNQYNPLRGSVAPGTLGTQA
PALPHSMMGPLHGGLSATALSQMLSYQALPSARLATQPHLAQAQQVQQQPSIQQQQQQQQ
QSLPPPPQPPQPHLGVSSAAGSHLGRGFLGGEPSQADVQPLGPSSLAVHTVLPQDSQVLP
TSLPSSLVPSMTTAQFLTPPSQHSCSSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSS
PHSNISDWSEGISSPPTSMQSQIAHIPEAFK
NT seq 7656 nt   +upstreamnt  +downstreamnt
atgccgccgctcctggcgcctctcctctgcctggcgctgctgcccgcgctcggcgcacga
ggcctgcggtgctcccagcccagcgagagctgcgtgaatggcgggacgtgtgaggtgtcc
gccaacggcacggaggcctgtgtctgcagccaggccttcgcaggccagcgatgccaggcg
cacagcccctgcctcagcgccccctgcaagaacggcgggacgtgccacgcggtggaccgg
ggtggcgcggtggactacgtctgcagttgccgcctgggcttctccggacccctctgcctg
acgccccgagacaacccctgcctcgccaacccctgccgcaacggcggcacctgcgacctg
ctgacgctcacggactacaagtgcctctgccccccgggctggtcagggaagatgtgccag
caagccgacccctgcgcctccaacccctgcgccaacggcggccggtgcctgcccttcgag
gccacgtacatctgcggctgcccgcccggcttccacggccctacctgccggcaggacgtg
aacgagtgtggccagagccccgggccctgccgcaacggcggcacctgcttcaacgaggtc
ggctcctaccgctgcgtgtgccgcgccacccacaccggcccccactgcgagctgccctac
gtgccctgcagcccctccccctgccagaacgggggcacctgccgccccacgggcgacacc
acccacgagtgcgcctgcctgccaggctttaccggccagaactgcgaagaaaatattgac
gactgtccggggaacagctgccagaatgggggcacctgcgtggacggcgtgaacacctac
aactgccgctgcccgcccgagtggacaggccagtactgcacccaggacatggacgagtgc
cacctcatccccaacgcctgccaaaatggcgggacctgccacaacaccctgggcggctac
aactgcgtgtgcgtcaatggctggacgggcgaggactgcagcgagaacattgacgactgc
gccagcgccgcctgcttccacggcgccacctgccacgaccgcgtggcctccttctactgc
gagtgtccccacggccgcacgggcctgctttgccacctcaatgatgcctgcatcagcaac
ccctgcaacgagggctccaactgtgacaccaaccccgtcaacggcaaggccatctgcacc
tgcccctcggggtacacggggccggcctgcagccaggacgtggacgagtgctcgctgggt
gccaacccctgcgagcacaagggaaagtgcctcaacacgctgggctccttccagtgccgg
tgtctgcagggctacaccggcccgcgctgcgagatcgacgtcaacgagtgcgtgtccaac
ccgtgtcagaacgacgccacctgcctggaccagatcggggagttccagtgcatctgcatg
cccggctacgagggcgtgtactgcgaggtgaacaaggacgagtgtgccagcagcccctgc
ctgcagaacggccgctgcctggacaagatcaacgagttccagtgcgagtgtcccccaggc
ttcaccgggaacctgtgccagtacgacgtggacgagtgcgcgagcacaccctgcaaaaac
ggcgccaagtgtctggacgggcccaacacctacagctgcgtgtgcacggaaggctacacg
ggaccccactgcgaggtggacatcgacgagtgtgaccccgacccctgccactacgggtcc
tgccaggacggcgtcgccgccttcacctgcctctgccagccgggctacacgggccaccac
tgcgagaccaacatcaacgagtgctacagccagccctgccgccacggaggcacctgccag
gaccgcgacaatgcctacctctgcctctgcctcaaggggaccacaggacccaactgcgag
atcaacctggacgactgcgccagcagcccctgcgacgcgggcacgtgtctggacaagatc
gacggctacgagtgtgcgtgcgagccaggctacacggggagcatgtgcaacatcaacatt
gacgagtgcgccagcagcccctgtcacaacgggggcacctgcgaggacggcgtcaacagc
ttcacctgccgctgccccgagggctaccatgaccccacctgcctgtctgaggtcaacgag
tgcaacagcaacccctgcatccatggggcctgccgggacagcctcaacgggtacaagtgt
gactgtgaccctgggtggagcggggccaactgtgacatcaacaacaacgagtgtgagtcg
aacccctgcgtcaacggcggcacctgcaaggacatgaccagtggctacgtgtgcacctgc
cgggaaggcttcagtggccccaactgccagaccaacatcaacgagtgcgcatccaacccg
tgtctgaaccagggcacttgcatcgatgacgtggcggggtacaagtgcaactgcctgctg
ccctacacaggagccacgtgcgaggtggtgctggctccgtgtgcctcccgcccttgcagg
aatggcggcgagtgcaaggcgtctgaggactacgagagcttctcctgcgtctgccctgtg
ggctggcaggggcagacctgcgaggtcgacatcaatgagtgtgtgaagagcccctgccgc
cacggtgcctcctgccagaacaccaacggcggctaccgctgccactgccaggcgggctac
acggggcgcaactgcgagacggacatcgacgactgccggcccaacccgtgccacaacgga
ggctcctgcacagacggcatcaacacggccttctgcgactgcctgcccggcttccagggc
gccttctgcgaggaggacatcaacgagtgcgccagcaacccctgccaccacggcgccaac
tgcaccgactgcgtggccagctacacctgcacctgccccgcgggcttcagtgggatccac
tgcgagaacaacacgcccgactgcacggagagctcctgcttcaacggtggcacctgtgtg
gacggcatcaactccttcacctgcctgtgtccacctggcttcacgggcagctactgtgag
cacgacatcaacgagtgcgactctcggccctgcctgcacggtggcacctgccaggacagc
tatggcacctacaagtgcacctgccccctgggctacaccggcctcaactgccagaacctt
gtgcgctggtgcgactcctccccatgtaagaacggtggcaggtgctggcagaccaacgtc
ctgtaccgctgcgagtgccacagcggctggaccggcctgtactgcgacgtccccagcgtg
tcctgcgaggcggccgcacggcagcgagacaccaacgtgacccacctgtgccggaacgga
gggctctgcgtggatgcgggcaacacgcaccactgccgctgccggccgggctacacgggc
agctactgcgaagaccaggtggacgagtgctcgcccaacccctgccagaacggggccacc
tgcaccgactaccctggcggctattcctgcgagtgcgtggccggctaccacggggtgaac
tgctccgaggagatcaatgagtgtctgtcccatccgtgccagaacgggggcacctgcatt
gacctcgccaacatgtacaagtgttcctgtccccggggcacacagggggtgcactgcgag
atcaacatggacgactgcaacccccccatcgaccccgtctcccgcggccccaagtgcttc
aacaacggcacctgcgtggaccaggtgggcggctacagctgcacctgcctgcccggcttc
gtgggcgagcgctgcgagggcgacgtcaacgagtgcctgtccaacccttgtgacgcccgc
ggcacccagaactgcgtgcagcgcgtcaacgatttccactgcgagtgtcgcccgggccac
accgggcgccgctgcgaggcggtcatcaacggctgcaaagggaagccctgcaagaacggc
ggcacctgcgcggtggcctccaacaccccccacgggttcatctgcaagtgcccggcgggc
ttcgagggctccacatgcgagaatgacgcgcgcacctgcggcagcctgcggtgcctgaac
ggcggcacctgcatctcgggcccgcgcagccccacctgcctgtgcctgggcaccttcacg
ggccccgagtgccagttcccagccagcagcccctgtgtgggcggcaacctctgctacaac
cagggcacctgcgagcctgtgcccgagaacccgtactaccgctgcctgtgtcccgccaag
ttcaacgggctccattgccacatcctggactacagcttccggggcggcgtgggcctggac
atcaccccgccgcagatcgaggaggcctgcgagctgcccgagtgccgcgaggaggctggc
aacaaggtctgcagcctgaggtgcaacaaccacgcgtgcggctgggacggcggcgactgc
tccctcaacttcaacgacccgtggcagaactgcacgcagtcgctcgagtgctggaagtac
ttcagcaacggccactgcgaccaccagtgcaactcggccggctgcctcttcgacggcttc
gactgccagcacaccgagggccagtgcaaccccctgtacgaccagtactgcaaggaccac
ttcggcgacgggcactgcgaccagggctgcaacagcgcggagtgcgagtgggacgggctg
gactgcgccgaccatgtgccggaacggctggcggccggcacgctggtggtggtggtgctc
atgccgccggagcagctgcgcaaccactcgttccgcttcctgcgggagctcagccgcctg
ctgcacaccaacgtggtcttcaagcgcgacgccgacggccagcagatgatcttcccgtac
tacggccacgaggaggagctgcgcaagcaccccatcaagcgctccctggatggctgggcc
gcgcccggcgccctgctcgaccaggtgaaggccgcgctgctcccggacggcagcggcggg
cgctggcgcagggagctggacccgatggacatccgcgggtccatcgtctacctggagatc
gacaaccggcagtgcgtgcaggcctctgcgcagtgcttccacagcgccaccgacgtggct
gccttcctgggcgcgctcgcctcgctgggcagcctcaacatcccctacaagatcgaggcc
gtgcagagtgagacggtggagccgcccccgcccccgccgctgcacttcatgtacgtggct
gtggcggccttcgtgctgctcttcttcgtgggctgcggtgtgctcctgtcccgccggcgc
cggcggcagcatggccagctctggttccccgagggcttcaaggtgtcggaggccagcaag
aagaagcggcgggagcccctcggcgaggactccgtgggcctcaagcccctgaagaactcc
tcggacggcgccctcatggatgacaatcaaaacgagtggggtgacgaggacctggaaacc
aagaagttccggttcgaggagccggtggttcttcctgacctggatgaccagacagaccac
cggcagtggacccagcaacacctggacgccgccgacctgcgcgtgcctgccatggcgccc
acgccaccgcagggcgaggccgatgcagactgcatggacgtcaacgtccgcgggcctgac
ggcttcacgcccctcatgatcgcctcctgcagcggagggggcctggagacaggcaacagc
gaagaggaggaggacgcgccggccgtcatctcggacttcatctaccagggcgccagcctg
cacaaccagaccgaccgcaccggcgagaccgccctgcacctggccgcccgctactcacgc
tccgacgcggccaagcgcctgctggaggccagcgccgacgccaacatccaggacaacatg
ggacgcaccccgctgcacgcagccgtgtctgccgacgcacagggcgtcttccagatcctg
atccggaaccgagccacagacctggacgcccgcatgcatgacggcacgaccccgctgatc
ctggccgcccgcctggccgtggagggcatgctggaagacctcatcaactcgcacgctgac
gtcaacgccgtggacgacctgggcaagtctgccctgcactgggcggccgccgtgaacaac
gtggaggctgcggttgtgcttctgaagaacggcgccaacaaggacatgcagaacaacaag
gaggagacgcctctgttcctggccgcccgggagggcagctatgagaccgccaaggtgctg
cttgaccacttcgccaaccgggacatcacagaccacatggaccgcctgccacgcgacatc
gcgcaggagcgcatgcaccacgacatcgtgcggctgctggacgagtacagcctggtgcgc
agcccccagctgcacggcgccgccctgggcggcccacccaccctgtcgccccccctgtgc
tcgcccagcggctgcctgggcaccctcaagccgaccgtgcagggcaagaaggcccgcaag
cccagcaccaagggcctggccggaggcggcaaggaggcccgggacctcaaggcccggagg
aagaagtcgcaggatggcaagggctgcctgctggacagcgcgagtgtgctgtcgcccgtg
gactccctggagtcgccacacggctacctgtcggatgtggcctcgccgcccctcctgccc
tccccgttccagcactccccgaccgtgcccctcaaccacctgcccggcatgcccgacgcc
cacctgggcattggccacctgaacgtggcagccaagccggagatggcggcgctgggcggg
ggtgggcggctggccttcgaggcagggccaccccgcctctcccacctgcctgtggcctcc
ggcactggcacggtcctggggaccagcggtggcagcggggccgtaaatttcactgtgggt
gcgaccacgggcttgaacggccagtgcgagtggctgtcccggttgcagaacggccttgta
ccaaaccagtacaaccctctgcgagggagcgtggcgccgggcacactgggcacgcaggcc
ccggccctcccgcacagcatgatgggcccgctgcacggcggcctctctgccaccgccctg
tcccagatgctgagctaccaggccctgcccagtgcgcggctggccacccagcctcacctg
gcgcaggcacagcaggtgcagcagcagccaagcatccagcagcagcagcagcagcagcag
cagagcctgccgccgccgccccagccgccccagccgcaccttggcgtgagctcggccgcc
ggcagccacctgggccgcggcttcctgggcggggagccaagccaggcagacgtgcagccg
ctgggccccagcagcctggccgtgcacaccgtcctgccgcaggacagccaggtcctgccc
acctcactgccctcgtccctggtcccgtccatgaccacggcccagttcctgacgccaccc
tcccagcacagctgttcctcctcgcctgtggacaacacccccagccaccagctgcaggtg
cccgagcaccccttcctcaccccgtcccccgagtcccccgaccagtggtccagctcgtcc
cctcattccaacatctccgattggtccgagggcatctccagcccgcccaccagcatgcag
tcccagatcgcccacatcccggaggccttcaagtga

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