Pteronotus mesoamericanus (Parnell's mustached bat): 129079193
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Entry
129079193 CDS
T09558
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
129079193 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ppam03021
]
129079193 (SETX)
Enzymes [BR:
ppam01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
129079193 (SETX)
5.6.2.5 RNA 5'-3' helicase
129079193 (SETX)
Transcription machinery [BR:
ppam03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
129079193 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
SLFN-g3_helicase
nSTAND3
ResIII
AAA_16
Helicase_RecD
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
129079193
NCBI-ProteinID:
XP_054440162
LinkDB
All DBs
Position
Unknown
AA seq
2709 aa
AA seq
DB search
MSTCCWCTPGGVSTTDFLQRYASRAQASDFQTADEDLCYCLECVIEYHRARDELPFLHEV
LWELETLRLINHFEKSMRAEIEDDDELYIVDNNGEAQLFDLTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFEKQPGIYLFLVHPNEMVRRWAILTAKGLGK
VERDDYYDLQEVLTCLFKVIELGLLENPDIYTSSVLEKGKLVILPSHMYDATSCKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSEDDGEDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTKSEPEPCLDDMVTCSQIVYNFN
PEKTKKDSGWRSAVCPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHAQVKDVLNQAVVMCDKVTEFFFLILVSVIELHRSKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFVRSSEKSSGSGSKGTAVTSLSLHPMPSNSVQLACVQLIRS
LLKEGYQLGQQTLCKQFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKAPQ
HSALVELSPSCKTPPASYSKEESEQIGKTCEKDMHCLGSPTFSKPLKTDVCQSPQSSILS
RASNTIEEDNEQHYVKDLKLEDRVSAESCLKQSSKNLFTERAQDRVTVRTGKQKSVKDDS
LYTPQSCISRSGPERGHDQGTVMSTCLLMDSNTDPLEKGSTSKEDFSLQDDVLGRTSKPK
TRAPKSEICAKLSHVIKKQHSALVNNTVKLEGNLTEPNIENVCSRNVTEDQKGIFLHDLT
LDPNDSLENKNGGHKSHNRLLPKKKQLKNEEELDGFSSHENDCQIQECHVGTKDVISFAE
VTSTFMHKTSPFKDPVSSLESRHKKIVSKSADQVSSNLIEQVPSISLQSDILTDSQIDRD
LHKLSLIAQASVTKFPSDSTQKSSPQLQRKVEDKRSFRANQNNVRETCGQIIIISDSDDD
GDDEGIMGFQKHMKQENMCTEKECPEQCTSMANTNMERKLTKEEKTDSPLNFEDADSQIF
EFESQKDVFSVWQDQKPDNKNSVQGDEKNSCWTHIADITNDWGYDTDYPMSEEVTKKGTE
GIECAQPQSSSTVEEFCELQVKKPKRKKLEKPMAKDGSRPSSSIRNENQSDNERELTENN
VKSTDIRTSPSAGVQRTTSVSLKKSSPKICAYSKPVRRAPVSKTKKTHSDTKKGQNKSSH
YISCRTTPFIVPPKKDRQCPEPTSTVEKLGLKKGRRRAFELSQRSLDYIEQLRDHGKNIG
VIDTRKKTKLISPQSLPVKDKKLLVSQDLQFQRQTRHRSKQNRQGHFDSKSTNAARAGPR
AAQKSEVFTPALGRPDYGNKGGTEVMASSSGTQSVKRTSPEQGPVKAKSVSQVAGDTCLL
NQCNSPVLHGRRPTNEITVPPSEDPLGGGDLTGHHLEVATLKKAEPDGDSDTEGNDIFLT
QHDPEDMDLCSQIQNDDDKLIEVVHGKHGVQVREDSIHQPQLEPLSSTKCKQRDCVETVK
SQGDYCPKHSEAKAADDDVFRKPGLPLSASKPLRPSTTKIFSSSSTSRIAHLSKSLESSS
ALPALKNKSSAGRSALKVPALPVSPKALSEAKGLCSVLPSPASPKPAGDVKSLCSVLSPP
ASPVSLKPLSEVKGLCNVLSPALSNSSRQAYRLPFGDSKPFSSSPDSTSPSQCITDMFVK
EVLKWKYEMFVNFSQCGLPASLCQAISRPVPVRFQDCGDYFNVFLPLMVVNTFETVAQEW
VSSPNKERFYELHLRKFPAEYKKYWEFVVSLEDCELSKQLHPKENDLVFLVPERQSGEKR
DVEGSPVQGPRDYHCAYVHKFRRTSVLRNGKYECFLCIQTQEDLPVSLNEFVKCIVISSL
VTTQRKLKAMALLNGRNQLARAILNPNPMDFCTKDLLTTTSERITAYLRDFNEDQKKAIE
TAYAMVKHSPAVAKICLIHGPPGTGKSKTIVGLLYRLLTERRGHLDENSNAKIKQNRVLV
CAPSNAAVDELMKKIILEFKERCKDKKNPMGNCGDINLVRLGPEKSINNEVLKFSLDNQV
NHRMKKDLPSYVQEMHRRKEYLDRQLDELSRQRALCRGGREMQRQELDERIAHVSKERQE
LASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQ
ACEVETLTPLIHRCNKLVLVGDPKQLPPTVISVKAQEYGYDQSMMARFCKLLEENVEHNV
SGRLPVLQLTVQYRMHPDICLFPSNYVYSRSLKTNRVTETIRCSSEWPFQPYLVFDVGDG
LERRDNDSYVNVQEIKVVIELIKLLKEKRKDVTFRNVGIITHYKAQKMMIQKELDKEFDG
KGRPAEVDTVDAFQGRQKDCIIVTCVRANTMQGSIGFLASLQRLNVAITRAKYSLFILGH
LRTLMDNQHWNHLIQDAQRRGAIIKTCDKNYKHDAMKILKLKPTLQRSLTHPPLLALEGF
SPQGGSPSSKPDSEIIKALFASFLYPTAPDPKEAAVTVAAKDPERPPGKDQLRDPRLLKR
LGLSSEAQGRCLRDPEPLSPQHHGATPPLGEPSCPVSPQALGATGEWSSASGSSHRPHVP
WDPPAASADAARKSVCDREREPSYRRDSRASRDRDREMPSPVSHHTRRNSGRDSRRWEKE
DSSAKRRKL
NT seq
8130 nt
NT seq
+upstream
nt +downstream
nt
atgagcacctgctgttggtgcacaccaggcggcgtctccaccactgacttcctgcagcgc
tatgcatcccgggcccaggccagcgatttccaaacagcagacgaagacctctgctactgc
ttggagtgtgtgatcgagtaccacagggcacgggacgagctgcccttcttgcatgaggtt
ttatgggaattagaaacattacgtctcataaatcactttgaaaaatccatgagagcagaa
atcgaagatgacgatgaattatatatagtagacaacaatggagaggcacaactgttcgac
cttactggccaagactttgagaataagcttcgagttcctcttcttgaaatactgaaatac
ccttatctgcttttacatgagcgtgttaatgagttatgtgttgaagcactttgtcggatg
gaacaagcgaattgctcctttcaggtttttgagaaacagcctgggatctatctgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgacagcaaaaggcttgggaaaa
gtggagagagatgattattatgacctgcaggaggttttgacatgcctttttaaagtcatt
gagttggggcttttagaaaacccagacatttacacttcctctgtccttgagaagggtaaa
ctggtcatcctgccctcacacatgtatgatgctaccagctgcaaaaactactggcttggg
atctgcatgctgctgaccatcctggaggagcaggccatggactcgctgctgctgggctca
gacaagcagaatgacttcatgcagtcgatacttcacaccatggagaagcagtcggaggat
gatggtgaagatcctttctggccagcattacactgtttcatggtgattctggatcgcctg
ggatctaaggtctggggtcaacttattgacccaattgaggcgtttcagaccattatcaac
aatgtgagctataatagagagatccagaatatccggaacagctctgtaaggaccaagtca
gaaccagagccatgcctggatgatatggtgacttgcagccagattgtatacaattttaat
cctgaaaagaccaaaaaggattcagggtggagatcagctgtttgcccagattactgtcct
aacatgtatgaagaaatggaaacgttagccaatgtgcttcagtcagatattggtcaagac
atgcgtgttcacaacagcacgtttctgtggttcatcccttttgttcagtccctcatggac
cttaaggatctgggtgtggcttatatagtggaggttattcaccatctgcatgcccaagtc
aaagatgtcctcaaccaagcagttgtcatgtgtgacaaggtcactgaattttttttccta
attttggtgtcagtgattgaactccatagaagtaaaaaatgcctgcacttgctctgggtc
agctcccagcagtgggtggaggccgtcgtgaagtgcgccaagctccccaccaccgcgttc
gtgcggagttctgagaagtcatccggcagtggctccaaaggaacagcagtgacctctctg
tccctgcatccaatgccatctaactcggtccaacttgcttgtgtgcagttgattagaagt
ctccttaaagaaggttatcagcttgggcagcagactctttgtaagcaattctgggataaa
ctcaacttattcctgcgaggaaatttatctctgggctggcagttgactagtcaggaaacc
catgagttacaaacttgtctaaagcaaattattaggaacatcaaattcaaggcacctcag
cactctgctttggtggagttgtctccttcgtgtaaaactcctcctgcatcttacagtaaa
gaagaaagtgagcaaatagggaagacatgtgaaaaagacatgcactgtctgggaagccca
accttttctaaaccattgaaaactgatgtatgtcagtcgccacagagtagtattttaagc
agagcaagtaacaccatagaagaggacaatgagcagcattatgtaaaagatttgaaacta
gaggaccgtgtctcagctgagtcatgcttaaagcagagtagtaaaaaccttttcactgaa
agagcccaagatcgagtgacggtacgtacagggaagcagaagtctgtaaaagacgattcc
ttatatacaccacagagctgtatttcaagaagtggtccagaaagggggcatgaccaagga
acagttatgtccacatgtctgttgatggattcaaacacggatcctctggagaaggggtcc
acatcaaaggaggatttctctctacaggatgatgttcttggcagaacctcaaaaccaaaa
actagggccccaaaaagtgaaatctgtgctaagttatcacatgtaataaaaaagcaacac
agtgctttggtcaataacactgtgaaattagagggaaacctgactgaacccaacattgag
aatgtctgttcaagaaatgttacagaagatcagaaagggatctttctacacgatctcact
ttagaccctaatgatagtctggagaataaaaatggaggacacaaatcccataacaggttg
ttgccgaagaagaaacagttgaagaatgaagaagagttagatggtttttcttcccatgaa
aatgattgtcaaatacaggaatgtcatgtcggcactaaagatgtgatctcatttgcagaa
gtgaccagtactttcatgcataagacatccccctttaaagatcctgtgagttcgcttgaa
tcaagacataagaaaattgttagcaagagtgctgatcaggtttcttctaatttgatagaa
caggtccctagcatcagtctgcagtctgacatcttaacagattctcagatagacagagac
ctccacaaactgtcattaatagctcaagccagtgttactaaattcccatcagattcaact
caaaaaagctcaccccagctacaacgaaaagtagaagataaaagaagtttcagagccaac
caaaataatgtcagggaaacctgtggacaaattattattatttcagattctgatgatgat
ggtgatgatgaaggaattatgggttttcagaaacatatgaaacaagaaaatatgtgcact
gagaaagaatgtccagagcagtgtacttcaatggctaatacgaacatggaaaggaagctt
acaaaagaggaaaagacagattctcccttgaattttgaggacgctgattctcagattttt
gagtttgaaagccaaaaggatgtattttcagtttggcaagatcagaaaccagacaataag
aattcagttcaaggagatgaaaaaaattcatgttggactcatatagctgatatcacaaat
gattggggttatgatactgattatcctatgtctgaagaagttactaagaagggaacagag
ggcattgaatgtgcacaaccacaaagtagtagtactgttgaggaattttgtgaactccaa
gtcaaaaaacctaagagaaaaaaacttgaaaaaccaatggctaaagatggttcaaggcct
tcatcttctatcagaaatgagaaccagtctgataatgagagagagctaactgaaaataat
gttaaaagtacagacataaggacctctcccagtgcaggtgttcagagaaccacttcggtt
tccctgaagaagtcttctccaaagatttgtgcttattccaagcctgttcggagagctccg
gtttctaaaactaagaaaacacattcggataccaaaaaagggcagaataaaagttcacat
tacataagctgcaggacaactccttttatcgtgccaccaaagaaagatcgccagtgtcct
gaaccaacttcaacagttgagaaacttggtctaaagaagggtcgtcgcagggcatttgag
ttgtctcagcgatctttagactatatagagcagttacgggaccatggtaaaaacattgga
gtgattgatacccgaaaaaagaccaaactgatttctcctcagtctcttcctgtgaaagat
aagaaactgcttgtgagtcaagatcttcagtttcaaagacagacgaggcacagatctaaa
caaaacagacaaggacattttgattcgaaaagtacaaatgctgcaagagcaggaccacgc
gcagcacagaagtctgaggtgtttacaccagcattggggaggccagattatggcaataaa
ggaggaactgaggtaatggccagcagtagtggaacccaatcagtaaaacgcacgtctcct
gaacaaggacctgtgaaagcaaaatctgtttctcaggtggctggtgatacttgtcttttg
aatcagtgtaactctccagtgttacatggaagaagaccaacgaatgaaatcacggtccct
ccttcagaggacccactaggtggaggggacctgactggacatcacctggaggtggcaact
ttgaaaaaggcagagcctgacggcgacagtgatacagagggaaatgatatctttttaaca
caacacgatcctgaagatatggatttatgttcacaaatacagaatgatgacgataaactc
attgaagtagttcatggaaaacacggggttcaggtcagagaagattccatacatcagcct
cagttggaacctttgagtagcacaaaatgtaagcagcgagattgtgttgaaactgtgaaa
agccagggcgactactgcccgaaacactcggaagcgaaagcagcagacgacgacgtcttt
cgtaagcccggcttgcctctttcggcatctaaacctttgagaccttccaccactaagatt
tttagctcaagtagtacttcacgaattgctcatctttccaagtctttggagagtagctca
gcacttccagctctaaaaaataagtcaagtgcaggtcggtctgctttgaaagtgccagcc
cttcccgtgtcaccgaaggcactgagtgaagcaaagggtttgtgcagcgttcttccttct
ccagcctctccgaagccagcgggtgacgtgaagagcctgtgcagcgttctttcccctccg
gcctctcccgtgtctctgaagccactgagtgaagtgaagggtttgtgcaacgtcctttct
ccggctctgagtaactccagcaggcaagcttacagactcccgtttggtgacagcaagcct
ttttcttcatctccggacagcacctcgccatcacagtgcatcactgacatgtttgtgaaa
gaggtcctaaagtggaaatacgagatgtttgtgaacttcagccagtgcgggctcccagca
agtctttgccaggccatctccaggcctgtgcctgtcagatttcaagattgtggcgattat
tttaacgtttttctccctttgatggtagtgaacacttttgaaacagtagcacaggaatgg
gtcagctctccaaataaagaaagattctatgagttgcatttacgaaaatttcctgcagaa
tacaaaaagtactgggagtttgtggtttctcttgaggactgtgaactatctaaacagctt
cacccgaaggagaatgatctggtgtttctggttcctgaaagacagagcggagagaagaga
gatgtcgaggggagccccgtccagggcccccgtgactatcactgtgcttacgttcataag
ttccgccgcacttcagtcctgcgtaatgggaaatacgaatgcttcctttgcatccagact
caagaggatttgccagtcagtctaaatgaatttgtaaaatgtattgtaatcagttctctg
gttactacacaaaggaaattgaaagccatggctttgttgaatggtcggaaccagctggcc
agagctattctgaatccaaaccccatggacttctgcacaaaagatttactgactacaaca
tctgagagaatcactgcctacttaagagatttcaatgaagaccagaagaaagcgatagaa
accgcatacgccatggtgaagcactccccggcggtggccaagatctgtctcattcacggg
ccgcccggaacggggaaatcgaaaacgatcgttggcctcctgtaccgcctgctgacggag
aggagggggcacttggatgaaaactccaacgcgaagatcaagcagaaccgcgtgctcgtg
tgtgcgccttccaacgcagccgtggatgagctgatgaaaaaaattatcctcgaattcaaa
gaaaggtgtaaagacaagaagaaccctatgggaaactgtggagatatcaatttagtacgt
ctgggtccagaaaagtctattaacaatgaggtcctgaagttcagcttggacaaccaagtc
aaccacagaatgaaaaaagatttaccgtcttatgttcaggagatgcatagaaggaaggaa
tacctagaccgtcagctagatgaactttcccgccagcgtgctttatgccgaggtgggagg
gaaatgcagaggcaagaattagatgaaagaattgcccacgtttccaaagagaggcaggaa
cttgcttctaaaattaaagaggttcaaggacgcccacagaaaactcagagcatcatcatc
ctggagtcccacatcatctgctgcaccctaagcacgagcggcggcttgctgctcgagtct
gccttccgggggcaaggaggggtccccttcagctgcgtcatcgtcgacgaggctgggcag
gcttgcgaagtggaaaccctcacccccctcatccaccgctgcaacaagctggtcctcgtg
ggagacccaaagcagctgccccccacggtcatctccgtgaaggcgcaggagtacggctac
gaccagtcgatgatggcccgcttctgcaagctgctggaggagaacgtggagcacaacgtg
agcggcaggctgcccgtgctgcagctgaccgtccagtacaggatgcaccccgacatctgc
ctcttcccctccaattacgtgtacagcaggagcctgaaaaccaacagagtgaccgagacc
atccggtgctcgtcggagtggccgtttcagccctacctcgtgttcgacgtcggagacggc
ttggaaagacgcgataacgactcgtatgtaaatgttcaagaaataaaagtggtcatagaa
ttgattaaacttcttaaagaaaaaagaaaggacgttactttccggaacgtcggcatcata
acccattacaaggctcagaagatgatgattcagaaggagttggacaaagaatttgatgga
aaaggtaggccagcagaggtagatactgtggatgcatttcagggtcgtcagaaagattgt
attattgttacgtgtgtcagagcgaacaccatgcaaggctctatcgggtttctggcgagt
ttgcagagattgaatgtagccatcacacgagccaagtacagcctcttcatcctcggacat
ctgaggaccttgatggacaatcagcactggaaccacctgattcaggacgcacagaggcgt
ggtgccatcatcaagacctgcgacaaaaactataaacacgatgcaatgaagatcctgaaa
ctgaagcccacgctgcagcgaagcctgacccacccgcctttgctagccctggaggggttc
agcccccagggcggctcacccagcagcaagccagacagtgaaatcatcaaggcgttgttt
gcgtctttcctctaccccacagcccctgaccctaaggaagctgctgttactgttgctgca
aaggaccctgagaggcctcctgggaaggaccagcttcgggacccacgactgcttaagagg
ttgggcctgagctctgaagcccaagggagatgcctaagggatccagagcccttgagcccc
cagcatcacggagccacgcctcccttgggcgagccgagctgccctgtgagcccccaggct
ctgggcgccaccggggagtggtcctcagcctcagggagcagccacaggccgcatgtgcca
tgggaccctccagctgccagcgctgatgccgcacgtaaaagtgtgtgtgaccgggaacgg
gagcccagctaccgaagggacagcagagcttccagggaccgggaccgggagatgcccagc
cctgtgagccaccacaccaggaggaactctggccgggacagcaggaggtgggagaaggag
gacagcagcgcaaagagaaggaagctgtag
DBGET
integrated database retrieval system
