Pteronotus mesoamericanus (Parnell's mustached bat): 129081426
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Entry
129081426 CDS
T09558
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam00310
Lysine degradation
ppam01100
Metabolic pathways
ppam05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
129081426 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
129081426 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ppam03036
]
129081426 (DOT1L)
Enzymes [BR:
ppam01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
129081426 (DOT1L)
Chromosome and associated proteins [BR:
ppam03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
129081426 (DOT1L)
HMT complexes
Dot1-containing complex
129081426 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
129081426
NCBI-ProteinID:
XP_054442950
LinkDB
All DBs
Position
Unknown
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTTIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPQSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDSVSLHLRGKGSLGRELEVEPGRLHLELDCSKFSLPHFSSMSPELSMNGHMAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASVKASAGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPQPSSPMALQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANAHGAGSNAAGSKGLALAPTGFSYTGSVAISGALAGSPAP
LAPGAEPPAFDESSSSGSLFTTMSSRSSTPQHHQLLVQPRNSGPASPTHQLCVSPRLSAA
QGPLPDSSKGDLPSEPGFSDPENEAKRRIIFTISAGGGSAKQSPSNKHSPLPGGTRGDSS
QSHGQDNRKRGRRKRASAGTPGLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQ
PLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQG
STRIERKIATISLESKSPPKTLENGGSVIGRKPVPSSEPINSSKWKSTFSPIADLSLAKA
ADSPLQASSALSQNSLFAFRPALEELGSVDAKLAAHPRKSFPGALSGAGGLSPVSNPPNG
FAFSGGLAADLSLHSFSDGASLSHKTPDVASLGSPLSFSAPRGKEGSTEPGPFVNKRQLD
VLGGPKGEGVKGREAEVGLPMCTPSDKASSHSKVGKGRDREPDFKNGHNLFISAAAVPTG
GLLSGPGLTTAVSSAGGTAPSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSV
PAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHAVPSSSTHPFGASFGSGAAC
RSTTLSLTPVQAVASTPASSFQALSSVETRQPPPQPPLSMGRPPAGPPALHEPPPPNVAL
PPAPAMLPANSEPVVLQKLAPLPANQAFLPASSAASLPPANASLSIKLASLPHKVSRPSF
MVHHQSLPGLALAQASPMIPQASSTGPSAMWVSLGMPPPYAARLAGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattatgtccta
attgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagttgtggaagggaaccacgcagcctatgaagctgaacacg
cggccatccaacgggctcctgcggcacatcctgcagcaggtgtacaaccactcagtgacg
gaccctgagaagctcaacaactatgagcccttctccccggaggtgtatggggagacctcc
ttcgacctggttgcacagatgattgacgaaatcaagatgacagaggatgacctgtttgtg
gacctgggaagtggagtgggtcaggtcgtgctgcaggtcgccgcagccaccaactgcaaa
catcactacggagtcgagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaatatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactacttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggaaaacaagagtaatacgaccaccccaacgaaggtgccc
gagagcaaggcagctgtgcctgcagacacctctgtggattctggtgctgaggaagagaaa
gcagcgacaactactatcaagaagccgtccccatccaaagcgcgaaagaagaagctgaac
aagaagggacggaagctggctggccggaagcgtgggcgtcccaagaagatgagcactgcg
aaccccgagcgtaagcccaagaagaaccctactgcactggacctgctgcacgcccagact
gtgtcccagacggctgcaccctcaccgcaggatgcgtacaagtcacctcaaagcccgttt
tatcagctacctcccagcgtgcagcggcatccccctgaccaactgctgttggcacctacc
ccacctgcactgcagaagctgctagagtccttcaagattcagtacctgcagttcctagca
tacacaaagacccctcagtacaaggccagtctgcagcagctgctggaccaggagaaggag
aagaatgcccgattgctgggtgccgcacagcagctatttggccactgtcaggcccagaaa
gaagaaataaagagactcttccagcagaaactggatgagttgggtgtgaaggctctgact
tacagcgacctgatccaagcacagaaggagatctcagctcacaaccagcagctgcgagag
cagacagagcagctggagaaggacaacagggagctaaggagccagagcttgcagctgctg
aaggctcggtgcgaggagctgaagctggactggtccacactgtccctggagaacctgctg
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcactgtctggagctg
cagatcagcatcgtggagctggaaaagagccagcggcagcaggagctcctgcagctcaag
tcctgcgtgccaccggacgactctgtgtccttgcacctgcgagggaaaggcagcctgggc
cgggaactggaggtggagcctggccgactacaccttgagctagactgctccaagttttca
cttccccactttagtagcatgagcccggagctctccatgaatggacacatggctggctat
gagctctgcaacacattgagccggccctcatccaagcagaacaccccccagtacttggcc
tccccactggaccaggaggttgtgccctgtacccccagccatagcagccggccccggctt
gagaagctgtctggcttggccttgccggactacaccaggctctccccagccaagctggta
ctgagacgccatctgagccaggaccacacagccagtgtcaaggcatctgctggcgagctg
catccacgagctgagcacaccaaggagaatggccttccataccagagcccaggcctcacc
aacggcatcaagctgagccctcaggacccacagccctcatcccccatggccttacagatg
acaggagaaaagggcagtgagaagggtctgaaggagcgcacctacgccagcagcggagag
gccatcaccagcctacccgtcagcatcccgctcagcactgtgcagcccagcaagctgcct
gtcagcatccccctggccagcgtggtgttgcccagccgtgccgagaaggtgagaagcacc
ccaagccctgtgcctcagacccgagagtcctcatccacacttgaaaagcagatgggtgct
aatgcccatggtgctgggagcaacgctgctgggagcaaaggcctcgccctggcccccaca
ggcttctcctacaccggctcagtggccatcagtggggccctggcaggcagcccagcccca
ctcgctcctggagctgagccccctgcctttgatgagtcctccagctcggggagcctcttc
accaccatgagctcccgcagctccaccccacagcaccatcaactgctggtgcagccccgg
aactccggtccggcctcacctactcaccagctctgcgtcagcccccggctcagcgctgcc
cagggcccactccctgattccagcaaaggagaccttccctctgagcctggcttctcggat
ccagagaacgaggccaagaggaggatcatcttcacgatctcagctggtggcggcagtgcc
aagcagtcgccttccaacaagcacagccctttgcctgggggcacccgcggagacagcagc
cagagccatggacaggacaaccgaaagcggggcaggaggaagcgggcctcagcagggact
cctggcctgagctcgggtgtgtcccctaagcgtcgggccttgccctccgtcgccggcctc
ttcacacagtcttcagggtcccccctcaacctgaactccatggtcaacaacattaaccag
cctttggaaatcacagccatctcgtctcctgaaagctccctgaagagctcccctgtccct
taccaggacaatgaccagccacccgtgctcaagaaagagaagcccctgagccaaaccaat
ggggcccactactccccgctcacctccgatgaggagccgggctctgaggacgagcaaggc
agcaccagaattgagaggaaaattgcaactatctccttagaaagcaaatctcctccgaaa
accttagaaaatggtggcagtgtgataggaaggaagccggtgccctccagcgagcccatc
aacagcagcaagtggaagtccaccttctcgcccatcgccgacctcagcctggccaaggct
gccgacagcccactacaggccagctccgctctgagccagaactccctgttcgctttccgg
cccgccctagaggagcttggctcggttgatgccaagctggccgcccaccccaggaagagc
ttcccgggtgcactgtcgggggctggcgggctgagccccgtcagcaaccctcccaacggc
ttcgccttcagcgggggcctggctgccgacctcagtttacacagcttcagtgatggtgct
tctctctcccacaagacccctgatgtggccagcctgggttcccccctgagcttttctgcc
cctaggggcaaggagggcagcacggagcctggcccctttgtgaacaagaggcagctggat
gtattgggtggcccaaagggcgagggggtcaagggcagggaggcagaggtgggcctgccc
atgtgcacgccctctgacaaggcctcgtcgcacagcaaggtgggcaagggccgggaccgc
gagcctgacttcaagaatggccacaatctcttcatttccgctgcggccgtgcctactggg
ggtctcctcagcggtccaggcctcaccacggcagtgtcttcagcaggcggcacagccccc
tcccagacacaccggcccttcctgggcacttttgcacctggcccgcagttcgccttgggc
cccatgtccctgcaggccaacctaggctcgtctgtgctgcagtccttgttcagctctgtg
ccggctgccgctggcctagtgcacgtctcatcagctgcaacaagactgaccaactcgcat
gccatgggcagcttttcctctggtgtggcaggcggtgcagttggaggtatctttaaccac
gcggtgccttcctcctccactcatccgtttggagccagtttcggcagcggggctgcttgt
cgcagcaccacgctgagcttaacccccgtgcaggcggtggccagtacccccgcctcttcc
tttcaggccctgtcttctgtggagacgaggcagcccccaccccagcctcctctgtccatg
ggtcgtccccctgcggggccaccagcactccacgagcccccccctcctaacgtcgccttg
cctcctgctcccgcgatgctccctgctaactctgagcccgtggtcctacagaaacttgcg
cccctcccggctaaccaagctttcttacctgcttcctctgctgcttctctgcctcctgct
aacgcctctctgtccatcaagctcgcctccctcccacacaaggtctcccgtccctccttc
atggtgcaccaccagtccctgccggggctggccctggcccaggcctcgcccatgatccca
caggccagctccacgggtccatccgccatgtgggtttcccttggcatgccgcctccttat
gccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
