KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129082351
Entry
129082351         CDS       T09558                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam04064  NF-kappa B signaling pathway
ppam04072  Phospholipase D signaling pathway
ppam04151  PI3K-Akt signaling pathway
ppam04380  Osteoclast differentiation
ppam04611  Platelet activation
ppam04613  Neutrophil extracellular trap formation
ppam04625  C-type lectin receptor signaling pathway
ppam04650  Natural killer cell mediated cytotoxicity
ppam04662  B cell receptor signaling pathway
ppam04664  Fc epsilon RI signaling pathway
ppam04666  Fc gamma R-mediated phagocytosis
ppam05152  Tuberculosis
ppam05167  Kaposi sarcoma-associated herpesvirus infection
ppam05168  Herpes simplex virus 1 infection
ppam05169  Epstein-Barr virus infection
ppam05171  Coronavirus disease - COVID-19
ppam05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    129082351 (SYK)
   04072 Phospholipase D signaling pathway
    129082351 (SYK)
   04151 PI3K-Akt signaling pathway
    129082351 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129082351 (SYK)
   04613 Neutrophil extracellular trap formation
    129082351 (SYK)
   04625 C-type lectin receptor signaling pathway
    129082351 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    129082351 (SYK)
   04662 B cell receptor signaling pathway
    129082351 (SYK)
   04664 Fc epsilon RI signaling pathway
    129082351 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    129082351 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129082351 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    129082351 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    129082351 (SYK)
   05168 Herpes simplex virus 1 infection
    129082351 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129082351 (SYK)
   05169 Epstein-Barr virus infection
    129082351 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    129082351 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppam01001]
    129082351 (SYK)
Enzymes [BR:ppam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     129082351 (SYK)
Protein kinases [BR:ppam01001]
 Non-receptor tyrosine kinases
  SYK family
   129082351 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7145 DUF7063 ABC1 SH2_1 RIO1
Other DBs
NCBI-GeneID: 129082351
NCBI-ProteinID: XP_054444015
LinkDB
Position
Unknown
AA seq 627 aa
MAAGMADHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY
TIERELNGTYAIAGGRAHASPAELCHYHSQESDGLVCLLKKPFNRPPGVQPKTGPFEDLK
ENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLI
GSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLVEHY
SYKPDGLLRVLTVPCQKIGRQTGNGPQLPSAHPATWSPSGIISRFASRSFLKPAHKKASS
SQGNRPESSMTFNPYEPDPGPWTADRETQREALPMDTGVYESPYADPEEIRPKEVYLDRK
LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD
NPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEEC
NFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK
FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYDLMNLC
WTYDVESRPGFAAVELRLRNYYYDVVN
NT seq 1884 nt   +upstreamnt  +downstreamnt
atggctgcaggcatggctgaccacctgcccttcttctttggcaacatcactcgggaggag
gctgaggactacttggtccaaggtggcatgagtgatgggctctacctgctgcgccagagc
cgcaattacctgggcggcttcgctctgtcagtggcacacgggcgcaaagcgcaccactac
accattgagcgagagctgaatgggacctatgccatcgcgggtggcagggcacatgccagc
cctgctgagctctgccattaccactcccaggagtcagatggcctcgtctgcctcctcaag
aaacccttcaaccggccacctggggtgcagcccaagactggaccctttgaggacctgaag
gagaacctcatccgggagtatgtgaagcagacctggaacctgcagggccaagctctggag
caggccattatcagccagaagcctcagctggagaagctgatcgccaccacagcccacgag
aaaatgccctggttccacggaaaaatctctcgggatgaatctgagcaaattgtcctgata
ggatcaaagacaaatggaaaatttttgatcagggccagggacaacaacgggtcctttgcc
ctatgcctgctacatgagggcaaagtgctgcactaccgtattgacaaggacaagacgggg
aagctctccatcccggatggcaagaagttcgacacactctggcagctagttgaacattat
tcgtataaaccagatggtttgttaagagttcttactgttccatgtcaaaaaattggccgg
caaacaggaaatggtccacaacttccaagtgcccatccagcgacttggtcaccaagtgga
ataatctcaagattcgcatcacgctccttcttaaagcctgcccacaaaaaggcctcctca
tctcaggggaaccgtccagagagctccatgacgttcaatccctatgagccagatccaggg
ccctggactgcagatagagaaacccagagggaagccttgccaatggacacaggagtgtat
gaaagcccctatgcggaccctgaggagatcaggcccaaggaggtctacctggaccggaag
ctgctgaccctggaagacaaagaactgggctctggtaactttggcactgtgaagaagggc
tactaccagatgaaaaaagttgtgaaaacagtggctgtgaaaatcctgaaaaatgaggcc
aatgacccagctctgaaggatgagctgttagcagaagccaacgtcatgcagcagctggac
aacccttacattgtgcgcatgatcgggatttgtgaagctgagtcctggatgctggttatg
gagatggcagaacttggtccactcaataaatatttacagcagaacaggcatgtcaaagat
aagaacatcatagagctggttcatcaggtttctatgggaatgaagtatttggaggagtgc
aattttgtgcatagagatctggctgcaagaaacgtattgctggttactcaacattatgcc
aagatcagtgattttggactttccaaagcacttcgtgctgatgaaaactactacaaggcc
cagacccatgggaagtggcccgtgaagtggtatgctccagagtgcatcaactactacaag
ttttccagcaagagtgacgtctggagcttcggggtgttaatgtgggaagcgttttcctat
gggcagaagccgtatcgggggatgaaaggaagtgaagtttctgctatgctggagaaagga
gagaggatggggtgccctccagggtgtcccagggagatgtatgatctgatgaacctgtgc
tggacatatgacgtggagagccggcccgggttcgcagctgtggaactgcggctgcgcaat
tactactatgacgtggtgaactaa

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