| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
ppam Pteronotus mesoamericanus (Parnell's mustached bat)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:ppam00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
129083713 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
129083713 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
129083713 (ABCC1)
04981 Folate transport and metabolism
129083713 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
129083713 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129083713 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:ppam02000]
129083713 (ABCC1)
Enzymes [BR:ppam01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
129083713 (ABCC1)
Transporters [BR:ppam02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
129083713 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1541 aa
MALRGFCSADGSDPFWEWNVTWYTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSHH
DRGYIQMTPLNKAKTALGFLLWIVCWADLFYSFWERSWVKFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDAEVDMFRDVTFYIYFS
LVLIQLVLSCFSDRSPLFSETTNDPNPCPESGASFLSRITFWWITGLMIRGYRQPLESAD
LWSLNKEDMSEQVVPILVKNWRKECAKSRKQPVKIVYSSKDPAKPKGSSKVDVNEEAEAL
IVKSPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDTKAPD
WQGYFYTALLFVCACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLTTYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPVN
AVMAMKTKTYQVAHMKSKDSRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KTAYLAAVGTFTWVCTPFLVALCTFAVYVTIDEHNVLDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELDPDSIERRPIKDGGSLNSITVKNATFTWARSDPPT
LNGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVSIKGSVAYVPQQAWIQNH
SLRENILFGRQLQERYYNAVIEACALLPDLGILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRLLVTHGISYLPQVDVIIV
MSGGKISEMGSYQELLAQDGAFAEFLRTYSSTEQEQTEQDDGSRAVDEDEEALAGMSGPG
KEAKQMENGMVVTDAAGKQVQRQLSSSSSYSGDVSRHHNSTAELQKAGAAAEDAWKMMEA
DKAQTGQVKLSVYWDYMKAIGLFISFLSFFLFLCNHVAALASNYWLSLWTDDPIVNGTQE
HTEVRLSVYGALGISQGIAVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPMSFFERTPSG
NLVNRFSKEMDTVDSMIPQVIKMFMGSMFNVIGACIIILLATPIAAVIIPPLGLIYFFVQ
RFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFAEQERFIHQSDLKVDENQKAYY
PSIVANRWLAVRLEYVGNCIVLFAALFAVISRNSLSAGLVGLSVSYSLQVTTYLNWLVRM
SSEMETNIVAVERLKEYSEIEKEAPWRIEAMAPSSTWPEAGRVEFRDYSLRYREDLDMVL
KHINITIDGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDNVNIAKIGLHDLRFKI
TIIPQDPVLFSGSLRMNLDPFSQYSDEEVWMSLELAHLKNFVSALPDKLNHECAEGGENL
SVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDNCTVLTIAHRLNT
IMDYARVIVLDKGEIRECGAPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4626 nt +upstreamnt +downstreamnt
atggcgctccggggcttctgcagcgccgacggctccgaccccttctgggagtggaatgtc
acatggtacaccagcaatcctgacttcaccaagtgctttcagaacactgtcctcgtgtgg
gtgccttgtttttacctctgggcctgcttccccttctacttcctttatctctcccaccat
gaccggggctacattcaaatgacacctctcaacaaagccaaaactgccttggggtttttg
ctgtggattgtctgctgggcagacctcttctactctttctgggaaagaagttgggtcaag
ttcctggccccggtgtttctggtcagcccaaccctcttgggcatcaccatgttgcttgct
acctttttaattcagcttgagagaaggaagggagtccagtcctcagggatcatgctcacg
ttctggcttgtagccctgctatgtgcccttgccatcttgagatccaaaatcatgactgcc
ttaaaagaggatgccgaagttgacatgtttcgtgatgtcactttctacatttacttcagc
ctcgtgctgattcagctcgtactgtcctgcttctcagaccgctcgcccctgttctccgag
accaccaacgaccccaatccttgcccagaatccggcgcatccttcctgtccaggatcacc
ttctggtggatcacggggttgatgatccgtgggtaccgccagcccctggagagcgccgac
ctctggtccctgaataaagaggacatgtcagaacaagttgtgcccattttggtcaagaac
tggaggaaggaatgtgccaaatccagaaagcagccggtgaagatcgtgtactcctccaag
gatcccgccaagcccaaagggagctccaaggtggatgtgaatgaggaggctgaggctctg
attgtcaagtccccccagaaggagcgggagccgtccctgttcaaggtgctctacaagacc
tttgggccctactttctcatgagcttcctattcaaggccctgcacgaccttatgatgttt
gccggcccggagatcttgaaattgctcatcaactttgtgaacgacacgaaggctccggac
tggcagggctacttctacacagcactcctgtttgtgtgcgcctgcctgcagaccctcgtg
ctgcaccagtacttccacatctgcttcgtcagtggcatgaggatcaagaccgctgtcatc
ggcgccgtctatcggaaggccctggtgatcaccaattctgccagaaaatcctccacggtt
ggggagattgtcaaccttatgtctgtggacgcccagaggttcatggacctgaccacgtac
attaacatgatctggtcagcccctctgcaagtcatccttgcgctctaccttctgtggctg
aacctgggcccctctgtcctggctggcgtggctgtgatgatcctcatggttcccgtcaat
gctgtcatggccatgaagaccaagacctaccaggtagcccacatgaagagcaaagacagt
aggattaagctgatgaatgaaattctcaacgggatcaaagtgctaaagctctacgcctgg
gagctggcattcaaagacaaggtgctggccatcaggcaggaagagctgaaggtgctgaaa
aaaactgcttacctggcagctgtggggaccttcacctgggtctgcacacctttcctggtg
gccctgtgtacgtttgcggtctacgtgaccatcgatgagcacaacgtcctggatgcccag
aaagcctttgtgtccttggccttgttcaacatccttcgttttcccctgaatattctcccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgcctcaggatctttctg
tcccacgaggagctggatccggacagcatcgagcgacggcccatcaaagatggcgggagc
ttgaacagtatcactgtgaagaatgccaccttcacgtgggcccggagcgaccctcccaca
ctgaatggcatcaccttctccattccagaaggttctttggtggccgtggtgggccaggtg
ggctgtggaaagtcatctctgctctcagcgctcttggccgagatggacaaggtggagggg
catgtgtctatcaagggctcagtggcctacgtcccacagcaggcctggattcagaatcat
tctctccgagaaaacatcctttttggacgccagctccaggaacggtattacaatgctgtg
atagaagcctgcgccctcctcccagatctgggaatcctgcccagcggggaccggacagaa
atcggcgagaagggtgtgaacctgtctgggggccagaagcagcgcgtgagcctggctcgg
gctgtgtactgtgactccgacatctacctctttgacgaccccctctcggcggtggatgcc
catgtcggaaaacatatatttgaaaatgtgattggccccaagggaatgctgaagaacaag
actcggctcctggtcacgcatggtatcagctacctgcctcaggtggatgtcatcattgtc
atgagtggtggcaagatctctgagatgggctcctaccaggagctgctggcccaggacggg
gccttcgccgagttcctgcgcacatactccagcacggaacaggagcagacggagcaggac
gacggcagcagagcggtggacgaggatgaggaagcattagcgggcatgagcggtccaggg
aaagaggcgaagcagatggagaatggcatggtggtgactgatgctgccgggaagcaagtg
cagagacagctcagcagctcctcctcctacagtggggatgtcagccggcatcacaacagc
actgcggagctgcagaaagccggggccgccgcggaggacgcctggaagatgatggaggca
gacaaggctcagacagggcaggtcaagctctctgtgtactgggactacatgaaggccatt
ggacttttcatctcctttctcagcttcttccttttcttgtgtaaccacgttgccgccctg
gcgtctaactattggctcagtctctggactgatgaccccatcgtcaacgggacccaggag
cacactgaagtccggctgagcgtctatggagccctgggcatctcgcaaggtatcgcggtg
tttggctactccatggcggtgtccatcgggggcatctttgcctcccgccgcctgcacctg
gacctgctacacaatgtcctgcggtcacctatgagcttctttgagcggacgcccagtggg
aatctggtgaaccgcttctccaaggagatggacacagtggactccatgatcccacaggtc
atcaagatgttcatgggctccatgttcaatgtcattggcgcctgcatcatcatcctgctg
gccactcccatcgctgctgtcatcatcccgcctctgggcctcatctacttctttgtccag
aggttctacgtggcctcctcccggcagctgaagcgcctggaatcagtcagccgctcccca
gtttactcccacttcaacgagaccttgctgggggtcagcgtcatccgggcctttgcggaa
caggaacgcttcatccaccagagtgacctgaaggtggacgagaaccagaaagcctattac
cccagcatcgtggccaacaggtggctggctgtgcggctggagtatgtgggcaactgcatt
gtcctgtttgcggccctgtttgcagtgatctcccggaacagcctcagcgcaggcttggtg
ggcctctcagtgtcttactcattgcaggtcaccacctatttgaactggcttgttcggatg
tcatcggaaatggagaccaacattgtggctgtggagagactcaaggagtattcagaaatc
gaaaaggaggctccctggcggatcgaggcgatggctccatccagcacctggcccgaggcg
ggccgagtggaattccgggactacagcctgcgttaccgagaagacctggacatggttctc
aagcacatcaacatcaccatcgatggaggggaaaaggttggcatcgtggggcggacagga
gctgggaagtcatccctgaccctaggcttatttcggatcaacgagtctgctgagggagag
attattattgacaacgtcaacattgccaagattggcctgcacgatctccgcttcaagatc
accatcatcccccaggaccccgttttgttttcgggttctctgcgcatgaacctggaccca
ttcagccagtattcggatgaagaagtctggatgtcgctggagctggctcacctgaagaac
tttgtatcagctcttcctgataagctgaaccacgagtgcgcagaaggcggggagaacctg
agtgttgggcagcgccagcttgtttgcttggcccgggccctgctgaggaagacaaagatc
cttgtgttggatgaagctacagcggccgtggacctagaaacagatgacctcattcagtct
accatccggacacagttcgacaattgtactgttctcaccattgctcaccgtctcaatacc
atcatggactacgcaagggtgatcgtcctagacaaaggagaaatccgggagtgtggcgcc
ccctccgacctcctgcagcagagagggttattttacagcatggccaaagatgctggtctg
gtgtga |
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