Pteronotus mesoamericanus (Parnell's mustached bat): 129084928
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Entry
129084928 CDS
T09558
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam05012
Parkinson disease
ppam05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
129084928 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
129084928 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129084928 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ppam04131
]
129084928 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ppam04147
]
129084928 (LRRK2)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129084928 (LRRK2)
Protein kinases [BR:
ppam01001
]
Serine/threonine kinases: TKL group
LRRK family
129084928 (LRRK2)
Membrane trafficking [BR:
ppam04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
129084928 (LRRK2)
Exosome [BR:
ppam04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
129084928 (LRRK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
LRR_4
COR-B
Ras
COR-A
ARMC6
LRR_9
Arf
WD40_CDC20-Fz
LRR_13
PduV-EutP
nSTAND3
Beta-prop_IFT122_1st
Beta-prop_EML_2
T2SSE
AAA_22
Beta-prop_THOC3
WD40_2
ABC_tran
GTP_EFTU
AAA_7
TrwB_AAD_bind
MobB
Ank_2
MMR_HSR1
Kdo
G-alpha
Beta-prop_RIG_2nd
NACHT
AAA_16
Septin
TsaE
SRPRB
AAA_29
NB-ARC
TniB
WD40_Prp19
nSTAND_NTPase5
cobW
ResIII
FtsK_SpoIIIE
ARM_CUL7_CUL9
AAA_14
SRP54
LRR_6
Motif
Other DBs
NCBI-GeneID:
129084928
NCBI-ProteinID:
XP_054447219
LinkDB
All DBs
Position
Unknown
AA seq
2527 aa
AA seq
DB search
MASGSCQGCEEKDEETLKKLIVRLNNLQEGKQIETLVQILEDMLVFTYADHASKLFQGKN
VHVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGRDWEVLGVHQLII
KMLTVHNASINLSTVGLKALDLLLTSGKITLLILDEENDIFLLIFDAMRTFSTNGEVQKL
GCKALQVLFERVSEEQLTEFVENKDYTILLSAFKNFKDEEEIVLYVLHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKTFPINEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAV
QQYSENATLQKAALSCLALLTETIFLNQDLEEKNENQENDDDEEEDKWFWLEACYKALTG
HRKNKHVQEAACWALNNLLMYQNNLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASA
NALSTLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDI
MVAVAPKIMTVMKNHETSLSVQLEALRAILHFIVPGMPGEFMEDTEYQHKLNMVTEQCFR
NDIHKLVLASLNRFTGNPGIQKCGLKVISSIAHLPDALDVLSPEGAIDSVLHTLQMYPDD
QEIQCLGLSLIGYLITKKNLFLGTGHLLAKILVSSLQRFQDVAELQIKGFQTVLTVLELS
ASFSKLLVHYSFDSVIFHQMSSSLMEQKDQQFLNLCCKCFATLAMDDELKSVMLERACDQ
SNSVMAECLLLLGADANRAKEGASLICQVCEKASNPKLVELLLNSGSREQDVRKALTISI
GKGDSQIISLLLRRLALDLANNSICLGGFGIGKIEPSWLGLLFPDKTPSSRKETNIGCTL
ARMVLRYQMKSAVEEGAASDSDGHFSEGVLDKLHEWTFIPESYVDSVFGQNDDLESEGSE
GSCLVKKKSNSISVGEFYLDPALQRCSPVLQRHSTSLGPIFSHDDLLKRKRKILSSDDSL
RSSKLPSYMRHSDSSSSLASEREYITSLDLSANELRDIDALSQKCGISGHLEHLEKLELH
QNALTSFPQRLSETLKCLTHLDLHSNKFTSFPSYLLKMNCIANLDVSRNDIGPSVVLDPA
VKCLTLKQFNLSYNQLSSVPENLGDVVEKLEQLMLEGNKISGMCSPLRLKELKILNLSKN
HISSLSEDFLEACPKVESFSARMNFLAAMPFLPSSMTSIKLSQNRFTCVPEAILHLPHLR
SLDMSSNDIKYLPSPAHWKSLNLRELLFSHNQISILDLSEKAHVWSRVEKLHLSHNKLKE
IPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDII
RFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSEPGMQSATVGIDVKDWPIQ
IKGKRKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIK
ARASSSPVILVGTHLDVSDEKQRKACIGKINKELLNKRGFPAIREYHFVNATEESDALAK
LRKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVKD
NQLQLDENELPHAVHFLNESGVLLHFQDPALQLSSLYFVEPKWLCKVMAQILTVKVEGYP
KHPKGIISRRDVEKFLSKKKRFPKNYMHQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPV
IELPHCENSEIIIRLYEMPYFPMGFWSRLISRLLEISPYMLSGRERVLRPNRMYWRQGIY
LNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEID
ICGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDL
ILADLPRNIMLNSDELEFEQAPEFLLGDGSFGSVYRATYEGEEVAVKIFNKHTSLRLLRQ
ELVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKATLTRTLQHRIALHVA
DGLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFR
APEVAKGNVIYNQQADVYSFGLLLYDILTSGGRIAEGLKFPNEFDELAIQGKLPDPVKEY
GCSPWPMVEQLIERCLKENPQERPTSAQVFDMLNSADLLCLMRHIPIHKNFIVECMVATN
HNSKNASVWLGCGNRERGQLSFLDLTTKRLTSEEVTDSRILCLALVHLPVEKESWIVSGT
QSGVLLVINTEDGNKRHTLESMTDSVTCLYCNSLSKLSKQKNFLLVGTADGNLAIFEDKA
VKCKGAAPLKTLHIGNISTPLMCLSESVNSSEKNITWGGCGTKLFSLSDDFTIQKLIETR
TSQLFPSAAFSDSNIIAVVVDTAAYIAKKNSPFVEVWDKKTEKLCELIDCVHFLKEEMVK
VNKESKHNMYYSGRVKTLCLQKNTALWIGTGGGSVLLLDLSTRRLIRIIHNFYDSVRVMM
TAQLGSLKNAMLVLGYSQKSTEGMQQKELQSFLSIWDINLPHEVQNLEKHIEVRKELAEK
MRRISVD
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcaggggtgcgaagagaaggacgaggaaactttgaagaagttg
atagtcaggctgaacaatctccaggaaggaaaacagatagagacgctggtccaaatcctg
gaagacatgctggtgtttacctacgcggaccacgcctccaagttatttcaaggcaaaaat
gttcacgtgcctctgttgatcgtcttggactcgtatatgagagttgctagtgtgcagcag
gtgggttggtcacttctatgcaaattaatagaaatctgtccaaatacaatgcaaagctta
atgggaccccaggatattggacgtgattgggaagtccttggtgtgcaccaactgattatt
aaaatgcttacagttcataatgccagtataaacctgtcaacggttggactgaaagcttta
gatctccttctaacttccggtaaaatcactttgctaatattggatgaagaaaacgatatt
ttcttattaatttttgatgccatgcgaacattttcaaccaatggcgaggtccagaaactc
ggttgcaaagctttacaagtgctgtttgagagagtttcagaggagcaactgactgaattt
gttgagaataaagattatacgatactgctaagtgcatttaaaaactttaaagatgaagag
gaaattgtgctttatgtactgcactgtttacattccctagcaattccttgcaataatgtt
gaagtcctcatgagtggaaatgtgagatgttataacattgtggtagaagccatgaaaaca
ttccctatcaatgaaaaaattcaagaagtgagttgctgcttgctccataggcttacatta
ggtaatttttttaatatcttggtattaaacgaggtacatgagtttgtggtgaaagccgtg
caacagtattcagagaatgcaactttgcaaaaagccgcgctcagctgtttagctctcctc
actgagaccattttcttaaatcaagacttagaggagaagaatgaaaatcaggagaatgat
gatgatgaggaagaagataagtggttttggctagaagcctgttataaagccttaacaggg
cacagaaagaacaagcatgtacaggaggctgcatgctgggccctaaataaccttcttatg
taccaaaacaatttgcacgagaagattggagatgaagatggccagttcccagctcacagg
gaggtgatgctctccatgctgatgcattcttcatcaaaagaagtctttcaggcatctgcg
aatgcattgtcgactctcttagaacaaaatgttaatttcagaaaaatcctgttgtcaaaa
ggaatatacctgaacgtgttagagttaatgcagaagcacatacattctcctgaagtggct
gagagtggctgcaaaatgctaaatcatctttttgaaggaagtaacacttccctggatatc
atggtagcagtggcccccaaaataatgacagttatgaaaaatcatgagacatcgttatca
gtgcagctggaggcacttcgagctattttacattttatagttccaggcatgccaggagaa
ttcatggaagatactgaatatcaacacaagctaaatatggttacagaacagtgtttcagg
aatgatattcacaaactggtccttgcttccttaaacaggttcactggaaatcctgggatt
cagaaatgtggattaaaagtaatttcttctatagcacatttacctgatgcattagatgtg
ttatctccggaaggtgctattgattcggtgcttcatacactgcagatgtatccagatgac
caagaaattcagtgtctaggtttaagtcttataggatacttgattacaaagaagaattta
ttcttgggaactgggcatctactggcaaaaattctggtttccagcttacaacgatttcag
gatgttgctgaattacagattaaaggatttcagacagtcttgacggtgctggaattgtca
gcgtctttttccaagctgctggtgcactattcctttgactcagtgatattccatcagatg
tcttccagtctcatggaacaaaaggatcaacagtttctaaacctttgttgcaagtgcttt
gcaacactagctatggatgatgagttaaaaagtgtgatgctggagagagcatgtgatcag
agtaacagcgtcatggctgaatgcttgcttctgttgggagcggatgccaatcgagcaaag
gagggggcttctttaatttgtcaggtatgtgaaaaagcaagcaatcccaaactggtggaa
ctcttactgaatagtgggtcccgtgaacaagacgtacggaaagcgctgacaataagcatt
gggaaaggtgacagccaaatcatcagtttgctcttacggaggcttgccctggacctggcc
aataacagcatctgccttgggggatttggtataggaaaaattgagccttcttggcttggt
cttttatttccggataagacacctagttcaagaaaagaaacaaatataggatgcacctta
gcaagaatggtcctcagataccagatgaagagtgctgtggaagaaggagcagcctcggac
agcgatgggcatttttctgaaggagtccttgataagctccacgaatggaccttcattcct
gagtcttatgtggacagtgtgtttggtcaaaatgatgacctggagagtgaaggaagtgaa
ggttcatgtcttgtgaaaaagaagtcaaactcaattagcgtaggagaattttacctagat
cctgccttgcagcgttgctcaccagttttgcaaaggcattccacttcattgggacccatt
ttcagtcatgacgatttactgaagcgaaaaagaaaaatactgtcttcagatgattcactc
aggtcatcaaaacttccatcctacatgaggcattcagacagcagttcttccctggcttct
gagagagaatatattacatcattagacctttcagcaaatgaactaagagatattgatgcc
ctaagccagaaatgcggtataagtgggcatttggagcatcttgaaaagctggagcttcac
cagaatgcactcacgagctttccacaacgactctctgaaactctgaagtgtttgacacat
ttggacttgcacagtaataaatttacatcatttccctcctacttgttgaaaatgaattgt
attgccaaccttgatgtctctcgaaatgacatcggaccctcagtagttttggatcctgca
gtgaagtgtctgactctgaaacagtttaacctgtcctataatcagctgtcttctgttccg
gagaaccttggtgatgtggtagagaaactggaacagctcatgctagaaggaaataaaata
tcaggaatgtgttcaccgctgaggctgaaggagctgaagattttgaaccttagtaaaaac
cacatttcatctctatcagaggattttcttgaggcttgccctaaagtggaaagtttcagt
gctagaatgaattttcttgctgctatgccttttttaccttcttcgatgacaagcataaaa
ttatctcaaaacagatttacatgtgttccagaagcaattttacatcttccacacttgcga
tccttagatatgagcagcaatgatattaaatatctaccaagtcccgcacactggaaatct
ttgaacttaagggaactcttgtttagtcataatcagatcagcatcttggacttgagcgaa
aaagcacatgtgtggtctagagtagagaaactacatctttctcataataaactcaaagag
attcctcctgagattggctgtcttgaaaacctgacatctcttgatgttagttacaacttg
gaactgagatcctttcccaatgaaatggggaaattaagcaaaatatgggatcttcctttg
gatgaactgcgtcttaattttgattttaagcatataggatgtaaagccaaagacatcata
aggtttcttcaacagaggttaaaaaaggctgtgccctacaaccgaatgaaactcatgatt
gtgggaaacaccgggagtggtaaaaccacgttattgcagcagttaatgaaaaccaagaaa
tcagaacctgggatgcagagtgccacagttggcatagatgtgaaagactggccgatccaa
ataaaaggcaaaaggaagaaggatctcattctaaatgtgtgggattttgcaggccgtgag
gaattctacagcactcatccccactttatgacccagcgagcgctgtaccttgctgtctat
gacctcagcaaagggcaggctgaagttgatgctatgaagccttggctattcaatataaag
gctcgggcttcttcttccccagtgattcttgttggcacacatttggatgtttctgatgag
aagcagcgcaaagcctgtataggtaaaataaacaaggaactcttgaacaagcgaggattt
cctgcaatacgggaataccactttgtgaatgccactgaggaatccgacgctttggcaaaa
cttcggaaaaccatcataaatgagagccttaatttcaagatccgagatcagcctgttgtt
gggcagctgattccagactgctatgtggagcttgagaaaatcattttatcagagcgtaaa
aatgtgccaattgaatttcctgtaattgaccggaaacgattattacaacttgtgaaagac
aatcaactgcagttagatgaaaatgagcttcctcatgcagttcacttcctaaatgaatca
ggggtccttcttcattttcaagatccagcactacagttaagtagcttatattttgtggaa
cccaagtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctatcca
aaacatcctaaaggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaag
agatttccaaagaactacatgcaccagtactttaaactcctagaaaaatttcagattgcc
ttgccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtg
atagagcttccccattgtgagaactctgaaattatcattcgactgtatgaaatgccttat
tttccaatgggattttggtcaagattaatcagtcgattacttgaaatttcaccttacatg
ctttcaggcagagaacgagtacttcgcccaaatcgaatgtattggcgacaaggcatctac
ttgaattggtcccctgaagcttattgtctggtaggatctgaagtcttagataatcaccca
gagagtttcttaaaaattacagttccttcatgtagaaaaggctgtattcttctgggccaa
gtcgtggaccacattgattctctcatggaagaatggtttcctgggttattggagattgat
atttgtggtgaaggagaaactttattgaagaaatgggcattatatagttttaatgatggt
gaagaacatcaaaaaatcttacttgatgacttaatgaagaaagcagaagaaggagacctc
ctagttaatccagaccaaccaaggctcaccattccaatatctcagattgctcctgacttg
attttggctgaccttcctagaaatattatgttgaatagtgatgaattggaatttgagcaa
gctccagagtttctcttaggtgatggcagttttggatcagtttatcgagcaacctatgaa
ggagaagaagtggctgtaaagatttttaataaacatacatcacttagactgttaagacaa
gagctggtggtgctttgccacctccaccaccccagcctaatatctttgctggcagccggg
attcgtcctcggatgctggtgatggagctggcttccaagggctccctggatcgcctgctg
cagcaggacaaagccactctcacgagaactctccagcacaggatcgcactgcatgtggct
gatggcttgagatatctccactcggccatgattatataccgtgatttgaagccccacaat
gtgctgcttttcaccctgtatcccaatgccgccatcattgcaaagattgctgactacggg
attgctcagtactgctgccgaatggggataaagacatcagaaggcacaccagggtttcgt
gcacctgaagttgctaaaggaaatgtaatttataaccaacaggctgatgtttattcattt
ggcttactactgtatgacattttgacaagtggaggtagaatagcagagggtttgaagttt
ccaaatgagtttgatgaattggcaatacaaggaaaattaccagatccagttaaagaatat
ggatgttccccatggcctatggttgagcagttaattgaaaggtgtttaaaagaaaatcct
caagaaagacctacttctgctcaggtttttgacatgttgaattcagctgatttactctgt
ctgatgagacatataccaatacacaaaaactttattgttgaatgcatggttgctacaaat
cataacagcaagaatgcaagtgtctggctgggctgtgggaacagagagagaggacagctc
tcctttcttgacttaaccaccaaaagactcacttctgaggaagttactgatagtagaata
ctgtgcctcgccttggtgcatttgcctgttgaaaaggaaagctggattgtgtctgggaca
cagtcaggcgtgctgctcgtcatcaatactgaagatggaaataagaggcataccctcgaa
agcatgactgattccgttacttgcttgtattgcaattccctttccaagctaagcaagcaa
aaaaattttcttttggtgggaactgctgatggcaacttagcaatttttgaagataaagct
gttaagtgtaaaggagctgctcctttgaagacactccatataggaaatattagcactcca
ctcatgtgtctgagtgaatcagtgaattcaagtgaaaaaaacattacgtggggaggatgt
ggcacaaaacttttctcgctttctgatgatttcaccattcagaaactcattgagaccagg
acaagtcagctgtttccttctgctgctttcagtgattccaacatcatagcagtggtggta
gacacagctgcctacattgcgaagaaaaatagcccgtttgtggaagtgtgggataagaaa
actgaaaaactgtgtgaactaattgactgtgtgcactttttaaaggaggagatggtcaaa
gtaaacaaagaatcgaaacacaatatgtattattctgggagagtgaaaactctctgcctc
cagaagaacactgctctctggatcggaactggaggaggctctgtgttactccttgatctt
tcaactcgtcgacttatacgtataattcacaacttttatgattcggttagagtcatgatg
acagcacagttaggaagccttaaaaatgccatgttggttttggggtatagccagaaaagt
actgaaggtatgcaacaaaaagaattacaatctttcttatctatttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacatattgaagtgagaaaagaattggctgaaaaa
atgagaagaatatctgttgactaa
DBGET
integrated database retrieval system
