Pteronotus mesoamericanus (Parnell's mustached bat): 129086248
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Entry
129086248 CDS
T09558
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01521
EGFR tyrosine kinase inhibitor resistance
ppam01522
Endocrine resistance
ppam01524
Platinum drug resistance
ppam04010
MAPK signaling pathway
ppam04012
ErbB signaling pathway
ppam04014
Ras signaling pathway
ppam04015
Rap1 signaling pathway
ppam04022
cGMP-PKG signaling pathway
ppam04024
cAMP signaling pathway
ppam04062
Chemokine signaling pathway
ppam04066
HIF-1 signaling pathway
ppam04068
FoxO signaling pathway
ppam04071
Sphingolipid signaling pathway
ppam04072
Phospholipase D signaling pathway
ppam04114
Oocyte meiosis
ppam04140
Autophagy - animal
ppam04148
Efferocytosis
ppam04150
mTOR signaling pathway
ppam04151
PI3K-Akt signaling pathway
ppam04210
Apoptosis
ppam04218
Cellular senescence
ppam04261
Adrenergic signaling in cardiomyocytes
ppam04270
Vascular smooth muscle contraction
ppam04350
TGF-beta signaling pathway
ppam04360
Axon guidance
ppam04370
VEGF signaling pathway
ppam04371
Apelin signaling pathway
ppam04380
Osteoclast differentiation
ppam04510
Focal adhesion
ppam04520
Adherens junction
ppam04540
Gap junction
ppam04550
Signaling pathways regulating pluripotency of stem cells
ppam04611
Platelet activation
ppam04613
Neutrophil extracellular trap formation
ppam04620
Toll-like receptor signaling pathway
ppam04621
NOD-like receptor signaling pathway
ppam04625
C-type lectin receptor signaling pathway
ppam04650
Natural killer cell mediated cytotoxicity
ppam04657
IL-17 signaling pathway
ppam04658
Th1 and Th2 cell differentiation
ppam04659
Th17 cell differentiation
ppam04660
T cell receptor signaling pathway
ppam04662
B cell receptor signaling pathway
ppam04664
Fc epsilon RI signaling pathway
ppam04666
Fc gamma R-mediated phagocytosis
ppam04668
TNF signaling pathway
ppam04713
Circadian entrainment
ppam04720
Long-term potentiation
ppam04722
Neurotrophin signaling pathway
ppam04723
Retrograde endocannabinoid signaling
ppam04724
Glutamatergic synapse
ppam04725
Cholinergic synapse
ppam04726
Serotonergic synapse
ppam04730
Long-term depression
ppam04810
Regulation of actin cytoskeleton
ppam04910
Insulin signaling pathway
ppam04912
GnRH signaling pathway
ppam04914
Progesterone-mediated oocyte maturation
ppam04915
Estrogen signaling pathway
ppam04916
Melanogenesis
ppam04917
Prolactin signaling pathway
ppam04919
Thyroid hormone signaling pathway
ppam04921
Oxytocin signaling pathway
ppam04926
Relaxin signaling pathway
ppam04928
Parathyroid hormone synthesis, secretion and action
ppam04929
GnRH secretion
ppam04930
Type II diabetes mellitus
ppam04933
AGE-RAGE signaling pathway in diabetic complications
ppam04934
Cushing syndrome
ppam04935
Growth hormone synthesis, secretion and action
ppam04960
Aldosterone-regulated sodium reabsorption
ppam05010
Alzheimer disease
ppam05020
Prion disease
ppam05022
Pathways of neurodegeneration - multiple diseases
ppam05034
Alcoholism
ppam05132
Salmonella infection
ppam05133
Pertussis
ppam05135
Yersinia infection
ppam05140
Leishmaniasis
ppam05142
Chagas disease
ppam05145
Toxoplasmosis
ppam05152
Tuberculosis
ppam05160
Hepatitis C
ppam05161
Hepatitis B
ppam05163
Human cytomegalovirus infection
ppam05164
Influenza A
ppam05165
Human papillomavirus infection
ppam05166
Human T-cell leukemia virus 1 infection
ppam05167
Kaposi sarcoma-associated herpesvirus infection
ppam05170
Human immunodeficiency virus 1 infection
ppam05171
Coronavirus disease - COVID-19
ppam05200
Pathways in cancer
ppam05203
Viral carcinogenesis
ppam05205
Proteoglycans in cancer
ppam05206
MicroRNAs in cancer
ppam05207
Chemical carcinogenesis - receptor activation
ppam05208
Chemical carcinogenesis - reactive oxygen species
ppam05210
Colorectal cancer
ppam05211
Renal cell carcinoma
ppam05212
Pancreatic cancer
ppam05213
Endometrial cancer
ppam05214
Glioma
ppam05215
Prostate cancer
ppam05216
Thyroid cancer
ppam05218
Melanoma
ppam05219
Bladder cancer
ppam05220
Chronic myeloid leukemia
ppam05221
Acute myeloid leukemia
ppam05223
Non-small cell lung cancer
ppam05224
Breast cancer
ppam05225
Hepatocellular carcinoma
ppam05226
Gastric cancer
ppam05230
Central carbon metabolism in cancer
ppam05231
Choline metabolism in cancer
ppam05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ppam05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129086248 (MAPK1)
04012 ErbB signaling pathway
129086248 (MAPK1)
04014 Ras signaling pathway
129086248 (MAPK1)
04015 Rap1 signaling pathway
129086248 (MAPK1)
04350 TGF-beta signaling pathway
129086248 (MAPK1)
04370 VEGF signaling pathway
129086248 (MAPK1)
04371 Apelin signaling pathway
129086248 (MAPK1)
04668 TNF signaling pathway
129086248 (MAPK1)
04066 HIF-1 signaling pathway
129086248 (MAPK1)
04068 FoxO signaling pathway
129086248 (MAPK1)
04072 Phospholipase D signaling pathway
129086248 (MAPK1)
04071 Sphingolipid signaling pathway
129086248 (MAPK1)
04024 cAMP signaling pathway
129086248 (MAPK1)
04022 cGMP-PKG signaling pathway
129086248 (MAPK1)
04151 PI3K-Akt signaling pathway
129086248 (MAPK1)
04150 mTOR signaling pathway
129086248 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129086248 (MAPK1)
04148 Efferocytosis
129086248 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
129086248 (MAPK1)
04210 Apoptosis
129086248 (MAPK1)
04218 Cellular senescence
129086248 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129086248 (MAPK1)
04520 Adherens junction
129086248 (MAPK1)
04540 Gap junction
129086248 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
129086248 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129086248 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
129086248 (MAPK1)
04613 Neutrophil extracellular trap formation
129086248 (MAPK1)
04620 Toll-like receptor signaling pathway
129086248 (MAPK1)
04621 NOD-like receptor signaling pathway
129086248 (MAPK1)
04625 C-type lectin receptor signaling pathway
129086248 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
129086248 (MAPK1)
04660 T cell receptor signaling pathway
129086248 (MAPK1)
04658 Th1 and Th2 cell differentiation
129086248 (MAPK1)
04659 Th17 cell differentiation
129086248 (MAPK1)
04657 IL-17 signaling pathway
129086248 (MAPK1)
04662 B cell receptor signaling pathway
129086248 (MAPK1)
04664 Fc epsilon RI signaling pathway
129086248 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
129086248 (MAPK1)
04062 Chemokine signaling pathway
129086248 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
129086248 (MAPK1)
04929 GnRH secretion
129086248 (MAPK1)
04912 GnRH signaling pathway
129086248 (MAPK1)
04915 Estrogen signaling pathway
129086248 (MAPK1)
04914 Progesterone-mediated oocyte maturation
129086248 (MAPK1)
04917 Prolactin signaling pathway
129086248 (MAPK1)
04921 Oxytocin signaling pathway
129086248 (MAPK1)
04926 Relaxin signaling pathway
129086248 (MAPK1)
04935 Growth hormone synthesis, secretion and action
129086248 (MAPK1)
04919 Thyroid hormone signaling pathway
129086248 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
129086248 (MAPK1)
04916 Melanogenesis
129086248 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
129086248 (MAPK1)
04270 Vascular smooth muscle contraction
129086248 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
129086248 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
129086248 (MAPK1)
04725 Cholinergic synapse
129086248 (MAPK1)
04726 Serotonergic synapse
129086248 (MAPK1)
04720 Long-term potentiation
129086248 (MAPK1)
04730 Long-term depression
129086248 (MAPK1)
04723 Retrograde endocannabinoid signaling
129086248 (MAPK1)
04722 Neurotrophin signaling pathway
129086248 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
129086248 (MAPK1)
04380 Osteoclast differentiation
129086248 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
129086248 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129086248 (MAPK1)
05206 MicroRNAs in cancer
129086248 (MAPK1)
05205 Proteoglycans in cancer
129086248 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
129086248 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
129086248 (MAPK1)
05203 Viral carcinogenesis
129086248 (MAPK1)
05230 Central carbon metabolism in cancer
129086248 (MAPK1)
05231 Choline metabolism in cancer
129086248 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129086248 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
129086248 (MAPK1)
05212 Pancreatic cancer
129086248 (MAPK1)
05225 Hepatocellular carcinoma
129086248 (MAPK1)
05226 Gastric cancer
129086248 (MAPK1)
05214 Glioma
129086248 (MAPK1)
05216 Thyroid cancer
129086248 (MAPK1)
05221 Acute myeloid leukemia
129086248 (MAPK1)
05220 Chronic myeloid leukemia
129086248 (MAPK1)
05218 Melanoma
129086248 (MAPK1)
05211 Renal cell carcinoma
129086248 (MAPK1)
05219 Bladder cancer
129086248 (MAPK1)
05215 Prostate cancer
129086248 (MAPK1)
05213 Endometrial cancer
129086248 (MAPK1)
05224 Breast cancer
129086248 (MAPK1)
05223 Non-small cell lung cancer
129086248 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
129086248 (MAPK1)
05170 Human immunodeficiency virus 1 infection
129086248 (MAPK1)
05161 Hepatitis B
129086248 (MAPK1)
05160 Hepatitis C
129086248 (MAPK1)
05171 Coronavirus disease - COVID-19
129086248 (MAPK1)
05164 Influenza A
129086248 (MAPK1)
05163 Human cytomegalovirus infection
129086248 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
129086248 (MAPK1)
05165 Human papillomavirus infection
129086248 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
129086248 (MAPK1)
05135 Yersinia infection
129086248 (MAPK1)
05133 Pertussis
129086248 (MAPK1)
05152 Tuberculosis
129086248 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129086248 (MAPK1)
05140 Leishmaniasis
129086248 (MAPK1)
05142 Chagas disease
129086248 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
129086248 (MAPK1)
05020 Prion disease
129086248 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
129086248 (MAPK1)
09165 Substance dependence
05034 Alcoholism
129086248 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129086248 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
129086248 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
129086248 (MAPK1)
04934 Cushing syndrome
129086248 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129086248 (MAPK1)
01524 Platinum drug resistance
129086248 (MAPK1)
01522 Endocrine resistance
129086248 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ppam01001
]
129086248 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ppam03036
]
129086248 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ppam04147
]
129086248 (MAPK1)
Enzymes [BR:
ppam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
129086248 (MAPK1)
Protein kinases [BR:
ppam01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
129086248 (MAPK1)
Chromosome and associated proteins [BR:
ppam03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
129086248 (MAPK1)
Exosome [BR:
ppam04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
129086248 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
129086248
NCBI-ProteinID:
XP_054448707
LinkDB
All DBs
Position
Unknown
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaacctctcttacattggcgagggcgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgcgtagccatcaagaaaatcagtccttttgag
caccagacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacac
gagaacatcattggtatcaatgatatcattagagctccaaccatcgagcaaatgaaagat
gtgtatatagtacaagacctcatggaaacagatctctacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttgaaatatatc
cattcagcaaacgtactgcaccgtgacctcaaaccttccaacctgctgctcaacaccacc
tgtgatctcaagatctgtgattttggcttggcccgcgttgcagatccagaccatgatcac
acagggttcctgacggagtatgtagccacacgttggtacagggctccagaaattatgttg
aattccaagggctataccaagtccattgatatttggtctgtaggctgcattctggcagag
atgctctccaacagacccatcttcccggggaagcattatctcgaccagctgaaccacatt
ctgggtattcttggatccccatcacaggaagacctgaactgcataatcaatttaaaagct
agaaactatctgctttctctcccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggatttactggacaaaatgttgaccttcaaccctcacaaa
aggattgaagtagaacaggctctggcccacccatatctggagcagtattatgatccaagt
gatgagcccatcgctgaagcaccattcaagtttgacatggaattggatgacttgcctaag
gagaagctcaaagaactcatttttgaagagactgctagattccagccaggatacagatct
taa
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integrated database retrieval system