Pteronotus mesoamericanus (Parnell's mustached bat): 129087035
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Entry
129087035 CDS
T09558
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
129087035 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ppam03032
]
129087035 (TOP2A)
03036 Chromosome and associated proteins [BR:
ppam03036
]
129087035 (TOP2A)
Enzymes [BR:
ppam01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
129087035 (TOP2A)
DNA replication proteins [BR:
ppam03032
]
Eukaryotic type
DNA Topoisomerases
129087035 (TOP2A)
Chromosome and associated proteins [BR:
ppam03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
129087035 (TOP2A)
Centrosome formation proteins
Centriole proteins
129087035 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
129087035
NCBI-ProteinID:
XP_054449793
LinkDB
All DBs
Position
Unknown
AA seq
1531 aa
AA seq
DB search
MEVSPLQPVNENMQINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGKAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTDCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKEAEKSDSVTGPTFNYLLDMPLWYLTKEKKD
ELCKLRNEKEQELETLKRRSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKAKG
KKAQMAEVLPSPSGKRVIPRVTIEMKAEAEKKNKRKIKNENTEGSPQEDSVEPEGLKQRL
EKKQKREAGTKAKKQSTLPFKPVKKGKKRNPWSDSESDMSGNESDFDAFDVPPREIEPRR
AAAKTKFTVDLDSDEDFSDFDKKSEDEDFVPSDASPIRTKTSPKPANKELKPQGSTSDHG
VDDAKDNAPAPPSSPVADFPAETKIINPVSKKRVAVKKTTAKSQSSTSTAGAPKRAAPKG
AKKDPGLNSDAPQKPDLPKTKTRRKRKPSTSDDSDSNFEKMISKAATSKKYKEESDDFHV
ALDSAVAPRVKSGRTKKPIKYLEESDEDDLF
NT seq
4596 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccattgcagcctgtaaatgaaaatatgcaaatcaacaaaacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaaaacgcaactg
gaacatatcttgctccgtccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttatgatgaagatgttggcattaactacagggaagtaacgtttgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggacccc
aaaatgtcttgtattagagttacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagtcgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagcaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaatttacagtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaaa
gctggtgagatggaactcaagccctttaacggagaagattacacatgtattaccttccat
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtt
agaagagcatatgatattgctgggtccactaaagatgtcaaagtctttctcaatggaaat
aagctgccagtgaaaggattccgtagctatgtggatatgtatttgaaggataaggtagat
gaaactggcaatccacttaaagttatccatgaacaagtaaaccacagatgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcatcgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgtggatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacttttgactctcagacaaaagaaaac
atgactttacaagccaagagctttggatctacatgccaattgagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggctcaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcctaaa
cttgatgatgccaatgatgcagggggccgaaactctactgactgtacacttatcctgacc
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tacggggttttccctcttagaggaaaaatactcaatgttcgagaagcatctcataaacag
ataatggagaatgctgaaattaacaatatcataaagatcgtgggtcttcagtacaaaaaa
aactatgaagatgaagattcactgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagtcttcccgaatttgaagaatggaagagt
tctactccaaatcataaaaagtggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtatccaattcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcattttatggaggatagaagacaacggaagttacttggcctt
cctgaggattacttgtacgggcaaactaccacatacctgacttacaatgacttcataaac
aaggaacttatactgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtaaaggttgcccagctagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactgatgatgaccattatcaatttggctcagaattttgtggggagcaataat
ctgaacctgttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctagatacatcttcacaatgctcagtcctttggctcggttgttatttccacca
aaagatgaccacacattaaaattcttatatgatgacaaccaacgtgtggagcctgaatgg
tacattcctattatacccatggtgctgataaatggggctgagggaattggtactggttgg
tcctgcaaaatacccaactttgatattcgtgaagttgtgaataacatcaggcgattgatg
gatggagaagaacctttgccaatgcttccaagttataagaacttcaagggtactattgaa
gagctggcttcaaatcaatatgtcattagtggtgaagtggctattctcaattccacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaggttcta
gaacccatgttgaatggcaccgagaagacgcctcctctcataacagattatagggaatac
cacacagataccactgtgaagtttgttgtaaagatgactgaagaaaaactggctgaggct
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatacgacacagtgctggatattctaaga
gacttctttgaactcagactgaaatattatggattaaggaaagaatggcttctaggaatg
cttggcgccgaatctgctaaactgaacaatcaggcacgctttatcttagagaaaatagat
ggcaaaataatcattgaaaacaagcctaagaaagaattaattaaagttttgattcagaga
ggatatgattcagatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaagctgaaaagagtgactctgtaactgga
ccaactttcaactaccttcttgatatgcctctttggtatctgaccaaagaaaagaaggat
gaactgtgcaaactaagaaatgaaaaagagcaagagctagaaacattaaagaggaggagt
ccatcagatttgtggaaagaagatctggctgcttttattgaagagctggaggctgttgaa
gccaaggaaaaacaagatgaacaagtaggactgcctgggaaaggggggaaagcaaagggg
aaaaaagcgcaaatggctgaagttttgccttctcccagtggaaaaagagtcatcccccga
gtaaccatagagatgaaagcagaggcagaaaagaaaaataaaaggaaaattaagaatgaa
aatactgaaggaagccctcaagaggacagtgtggaaccagaaggcctaaaacaaaggcta
gagaagaaacagaaaagagaagcaggtaccaaagcaaagaaacaaagtacattgccattt
aaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcggaatcggatatgagc
ggtaacgaaagtgactttgatgcctttgatgtccctccacgagaaatagagccacgaaga
gcagcagcaaaaaccaaattcacagtggatttggattcagatgaagatttctcagatttt
gataagaaaagtgaagatgaagattttgtcccatcagatgctagtccaattaggaccaaa
acttccccaaaacctgcaaacaaagaactgaagccacagggaagcacatcagaccatggt
gttgatgatgccaaagacaacgcaccagctcctccaagctcacctgtggctgacttccca
gccgaaaccaaaatcataaaccctgtttctaaaaagagagtagcagtgaagaagacgaca
gcaaaaagtcagtcttccacctccactgcaggtgcccctaaaagggctgcaccaaaagga
gccaaaaaggatccaggcttgaattctgatgcccctcaaaagcctgatctccccaaaacc
aagactcgccgcaaaaggaagccatctacttctgatgattccgactctaattttgagaaa
atgatttctaaagcagccacaagcaagaaatacaaggaggagagtgatgacttccatgtg
gccttagactcagctgtggcccctcgggtaaaatctggacggacaaagaaacctataaag
taccttgaagaatcagatgaggatgatctgttttaa
DBGET
integrated database retrieval system
