Phlebotomus papatasi: 129802074 Help Entry 129802074         CDS       T10447                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism ppap  Phlebotomus papatasi Brite KEGG Orthology (KO) [BR:ppap00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ppap04040]     129802074    04990 Domain-containing proteins not elsewhere classified [BR:ppap04990]     129802074 Ion channels [BR:ppap04040]  Voltage-gated cation channels   Ryanodine receptor    129802074 Domain-containing proteins not elsewhere classified [BR:ppap04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    129802074 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 DUF996 Motif Other DBs NCBI-GeneID:  129802074 NCBI-ProteinID:  XP_055703610 LinkDB All DBs Position 2:complement(1635809..1678654) Genome browser AA seq 5143 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETEKDSLGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSSW ANEPGQNIVIYEGGSVMSQARSLWRLELARTKWSGGFINWYHPMRIRHLTTGRYLAVNEN NELCLLGRDDANISCSTFCLRQEKDDQKIVLEDKDLEIIGSPIIKYGDSTVILQHSESGL WLSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESKTARVIRKCSSLFTKF IHGLERLQENRRHSIFFQTVNLSEMVMCLEDLINYFAQPDDDMEHEEKQNRFRALRNRQD LFQEEGVLNLILEAIDKINVITSQGFLASFLASDESGQSWELISGYLYQLLAAIIKGNHT NCAQFANTNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLE KHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVG RVEGSAMYQKWYFEITMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGEKWGGNGVGDDLY SFGFDGAHLWTGGRNISVVSADVQEPYIRKGDVIGCALDLTVPIITFTFNGAKVRGSFRD FNLDGMFFPVLSCSSKLSCRFLLGGDHGRLKYAPPLGFSPLVQCLMPHQVLSLDPCFYFG NLYKNVLAGPWLVEDDTPFVPQPVDTVNVSLPSFVDTIKDKLAENIHEMWALNKIEAGWC WGEYRDDLHKIHPCLTQFERLPAAEKRYDCQLAVQTLKTIIALGYYITLDKPPARIRPIR LPNEPFMQANGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWAKERIQQGWTYGLNEDS ENHRSPHLVPYVKVDEAIKKANRDTASETVRTLLVYGYNLDPPTGEGNEALLAEAQRQKF AAFRTYRVEKNYAVTSGKWYFEFEVLTAGPMRVGWARADCNPGTMLGNDDSTWAFDGYNE EKVSGGSTESFGKQWVPGDVVGVFLDLVDHTISFSLNGELLMDALGGETTFADVTADGVG FVPACTLGVGQKARLIYGQNVDSLKWFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFEN TEDFIDCRIDVTRIPGGADTPPCLKISHNTFETMEKANWEFLRLSLPVICQSAFITETEK MHRWEEIKMRQNRILAEVEQTTPAHFDHIMRSGFTMNDIKGLHRNYNEDAAEADEQMLRP NPARPPRKGSLSRGSIAPYDPPTIEINSKIQRSTSELDMNAYGEIGEKDDKKKRGRSPFK FFSKKNRDQSKDKLKAKTPEPGDRRTTSTQGRNVIQSQTMTRTPTVRVSNADLRVQPPAV PDRPKTMTVNALGSNSIESVGNEVYDAECLKLINEYFYGVRIFPGQDPTHVWIGWVTTQY HRHSNEFNQQTVRRVAVAMEDDYETIMGRVNRQSCYMVRADELFNEVTQDASGKGASQGM FVGCFVDTATGTIRFTCEGKETSHKWVMEPDTKLFPAIFVEATSKEVLQIELGRTPTTLP LSAAVLPTGDKHVNPQFPPRLKVQCLKPHQWARVPNNALQVHALKLSDIRGWSMLCEDPV SMLALHIPEEDRCIDILELIEMDKLLSFHSHTLTLYAALCYQSNYRAAHALCLHVDQKQL LYAIKSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEFIIPLGPELTELYKETEMCHS LRSLQTESVRPQMKMTEIASPMPNVPIVVANGVSSEPIPTIDALYSPRFPLEIVREFVME ALAEAVEINQVHNRDPIGGSNENLFLPLIKLCDRLLLVGIMKDEDIEKLLIMIDPETWDG SFDKEGKDEHRKGLLTMKMAEGAKLQMCYLLHHLCDVQLRHRVESIIAFSNGFVGDLQAD QLRRYIEIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKALEDDDIENCPCGVELRDAL NEFHGQLMTKVSLNALQDSEEDDSGAADTGKTGPLSKLFNFINTVKELEEEPKEAIEPVK KTPEEIFRKVLIKTIVSWAEESQIETPKLVREMFGLLVRQYDTVGELIKALEKTYVINSK TKNDVAGMWVGLSQIRALLPVQMSEEEEKLMRTRLWKLVNNHTFFQHPDLIRILRVHENV MAVMMNTLGRRAQAQSDAPVQSEGGEAPVKEKDTSHEMVVACCRFLCYFCRTSRQNQKAM FDHFDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGL QSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPA LRGEGEGLLRAIIDANKMSERIADRRKLQDEAEGTMAGLTFNHPLPESDDDEDYIDTGAA ILNFYCTLVDLLGRCAPDTAVIAQGKNESLRARAILRSLVPLEDLQGVLSLKFTLQNPAP GEEKPKSDMPSGLIPGHKQSIVMFLERVYGIETQELFYKLLEEAFLPDLRAATMLDRNDG SESDMALSMNRYIGNSILPLLIQHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQRE AVSDFLVALTAQMQPSMLLKLLRKLTVDVSRLSEYTTVALRLLTLHYDRCAKYYGSSGGQ GAYGSSSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNAD EDFYGKPSSAAAPDQPQYNPQPINTSAVVLDNDLNSIVQKFSEHYHDAWASRKLEAGWSF GEQWSDSQKFHPRLKPYNMLSDYERERYKEPVREALKALLALGWSVEHAEGDVPLSHRGS TRRTSKPNLEFQTDSSSPFNYNPQPIDMTNLTLSREMQNMAERIAENSHDIWAKKKREEL NTCGGAIHPQLVPYDLLTDKEKRKDRERSQEFLKYMQYQGYKLHKPSRGISADGEQAGGG PAIELRFAYSLLEKLIQYLDRATINMKLLKPSTTFSRRNSFKTSSRDIKFFSKVVLPLME KYFSTHRNYFIAVATATNNIGAASLKEKEMVAALFCKLASLLRYRLAAFGPDVRITVRCL QVLVKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGQTIFNLQDGKYSHLRGTHLKTSTS LAYVNTVILPVLTAMFDHLAGCEYGSDLLLDEIQVASYKILSSLYTLGIDASLTHDRKYL KTEIERHKPSLGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDIMAKMENS MPTLEAILQEVDQFVESDKTYNDAQHIIDVILPLLCSYLPFWWAQGPDNITPTTGNHVTM VTADHMNQLLKNVLKMIKKNIGNDNAQWMTRIAAYTQQIIINSSEELLIDPFLPLAERVR KRTDNMFHKEESLRGFIKSATDDTSQVEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHW LKNNIPEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRTQVISE GQQNTGGKIKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDR YLKKMSEDFVIEFARTQLTLPDKLDPADEMSWQHYLYSKLGKKEVEADEIVEKAKVTDEK KPENKIEDTVDRIVAMAKVLFGLHMANRPKQRSDKWQRIVSLARRKSALACLKAKPLYKM SRHRACNIFARTYHELWLQEENIGQEIMIEDLTQSFEDAEKAKKDAEEEESKPDPLTQLV TTFCRGAMTERSGALQEDALYMSYAQIAAKSCGEEEEEGGEEEGGGEEGESSGASIHKNT METLMEQEMEKQKLLFHQARLSNRGVAEMVLLHISASKGVPSDMVMKTLELGIAILRGGN IDIQMGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGAEGAAGEKNM HDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYW HYSSKEIIDPAGKANFFKAIGVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFL FSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNV ELILKYFDMFLKLKDLTSTPSFQEIDPNGDGWINPKDFQDKMEQQKSYTPEEIEFLLACC ERNHDGKIDYIDFVDRFHDPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFE AFLGRIEIMGSSKRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFV NFCEDAIFEMTHASALMATDEGGGNVRREASFSTYISEEEEEKAAKDPIKRTVQGVKDGF WFILHLFSVSNIKHQIAVAQTKSVPELFIGFFKMIFYAFYYSGLGVTLIIKYFLNILMSL MRGSGTEEIEAPPEPEASGLMRALPALPQEEPPGTVQAFGLDISKEENGQYKLAPHESPA ASPSSSMEETGESSPEDAAAAGEHGPEEGQEPPITLVDLLGGEAAKRAAQERSEAQKLQE AAMATIEAETKKSSAEPKEPAAVTQIDFSQYTHKIVSFLARNFYNLKYVALVLAFCINFM LLFYKVTTFGEDEGGSGEGELDLGFGSGGSGSGLGAILEGSANGEGEEGEEEDPLESVHV DEDFYYMEHVLRIAALLHSTVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQP EDDDIKSHWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFESISNLLGMEKSAFTTQE TEGGGLVHYIVNIDWRYQIWKAGVTITDNAFLYSLWYFTFSIFGNFNNFFFAAHLLDVAV GFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDEEVDKKCHDM LTCFVFHLYKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIVILLAIIQGLIIDA FGELRDQLESVKEDMESNCFICGIGKDYFDKVPHGFDTHVQQEHNLANYMFFLMHLINKP DTEYTGQETYVWNMYQQRCWDFFPVGDCFRKQYEEELGGGSGG NT seq 15432 nt NT seq  +upstreamnt  +downstreamnt atggctgaagcggaaggtggatctgagcaggatgatgtttcattcttacgcacggaagac atggtctgtctttcgtgcacagccactggagaacgagtatgtttagctgctgaaggcttt ggcaatcgacattgcttcctggaaaatatagccgacaagaatgtccctccggacctatcg caatgcgtctttgttattgagcaggctctctcagtcagagctcttcaggaacttgttaca gctgctggatctgaaaccgagaaagattccttaggcaagggaacaggatctggccacagg acacttctctatggcaatgccattcttcttcgccatcagaacagtgacatgtatttagcc tgtctctcaacatcgtcctccaatgacaaattgtccttcgacgtgggtctccaggaacac agtcaaggagaggcgtgctggtggactgttcatccggccagcaaacaacgatctgagggt gaaaaggtgcgtgtcggtgatgatttgattctggtgtccgtggccacagaaagatatctg cacaccaccaaagaaaatgaccagtccatcgtgaatgccagtttccacgtgacccattgg tctgtgcaaccttatggtacaggaatctcacgtatgaagtatgtgggttatgtctttgga ggagatgttctgcggttcttccatggtggtgatgaatgcctcacaataccgagctcctgg gccaatgaacctggtcaaaacatagtgatctacgaaggtggttctgtaatgtcgcaagcc agatctctctggcgattggaattagcgcgaacaaaatggtctggtggctttataaattgg tatcatcctatgaggattcgtcatttgacaaccggacgatatttggctgtaaacgaaaac aacgaactatgcttgcttggaagggatgatgcgaacatttcctgctcaactttttgtctg cgtcaagagaaggatgatcagaagattgttcttgaagacaaagatttggaaattattggt tcgccaatcataaaatacggtgattcaactgtaattcttcagcattcagagtcaggactt tggctgagttacaagagttatgaaactaagaaaaaaggcgtgggaaaagtcgaagagaaa caggctgttcttcacgaagaaggaaagatggacgatggactggacttttcgcgttcacag gaagaagaatcaaagacagctcgggtgatcaggaaatgtagcagtctcttcacaaaattt attcatggcttggagcgattgcaagaaaatcgaagacattcgatcttctttcaaacggtc aacctgtctgagatggtgatgtgtcttgaggatttaattaactatttcgcacaacctgac gatgatatggaacacgaagagaagcaaaatcgcttccgtgctttgaggaatcgtcaggat ctcttccaagaagaaggagtccttaacttgatcctcgaggctattgacaaaatcaatgtt atcacatcacaaggattcttggctagtttcctagctagtgatgaaagtggtcagagctgg gaactcatttctgggtatctctatcaattactagcagctataatcaagggcaatcacacg aattgtgctcagttcgctaacaccaaccgtctgaactggttgttctccagacttggttcg caagcctctagcgaagggtctggaatgcttgatgtacttcactgtgtgttgattgactct ccagaagctttgaacatgatgagggatgaacacatcaaagtaattatctctctactggag aagcacggccgagatcccaaagttctggatgttctgtgttccctctgcgtgggtaacggc gttgctgtcagatcatcgcagaacaacatttgcgatttcctcctaccgggaaagaacctt ttgctgcagactcagctcgtagatcacgttgctagcatcagaccaaatatcttcgttgga cgtgttgaaggatcagcaatgtatcagaagtggtacttcgaaatcacaatggatcacatc gaacagacaacccacatgatgccgcacttgcgaatcggctgggccaatacgtccgggtac gtcccgtatccaggcggtggagaaaaatggggtggaaatggcgttggtgatgatctgtat tcctttggcttcgacggtgcacacctttggaccggaggacgcaacatctccgttgtttcc gcagacgtacaggagccctacatccgaaagggtgatgtgatcggatgcgccttggatcta actgtgccgattataacatttacattcaatggggccaaagtacgtggaagttttagggat tttaatctcgacggtatgttctttcctgttctgagttgttcctccaagttgagttgccgt tttctactgggtggtgaccatgggcgcctgaaatatgccccaccacttggattttcgcct cttgttcagtgccttatgccccatcaagttctaagtctcgatccctgtttctacttcggt aatttgtacaagaatgtcctggcgggaccttggctcgtggaagacgataccccatttgtt ccacagcctgttgatacagtcaatgtcagtttgccatccttcgtggacacaatcaaagac aaactggctgagaacattcatgaaatgtgggctctcaataaaatcgaagctggatggtgt tggggtgaataccgagatgacctgcacaaaattcacccatgcctcacacagtttgagcgt cttccagctgctgaaaaacgctacgactgccaacttgcagtacaaacccttaagacaatc atagctctaggctactacattactctggacaagccaccagcccgaattcgaccaattcgc ttaccaaatgaaccctttatgcaagccaatggttacaaaccagccccattggatctcagt gctgtaactctaacgccgaagctggaagagctcgtggatcaacttgctgagaatactcac aatttgtgggcaaaggaaagaatccagcaaggatggacttatggtctcaatgaagattcg gaaaatcatcgtagtccacatttagtgccctacgtcaaggtagatgaagctatcaagaag gctaacagggacacagcttcagaaaccgtaaggacgcttctggtctatgggtacaatctg gatccgcctacgggcgagggcaatgaggctcttctggccgaagcacaacgacagaaattt gctgcatttcgaacgtatcgagttgaaaagaactacgccgttacatcaggaaagtggtac tttgaatttgaagtacttacagctggacccatgcgggttggttgggccagagctgattgt aatccaggaacaatgcttgggaatgacgatagcacttgggcatttgatggatacaatgaa gaaaaagtatccgggggctcaactgagtcctttggcaaacaatgggttcctggtgatgtc gttggtgtcttccttgatttggtggatcacaccatcagtttctctctgaatggtgaattg ttgatggatgcattgggtggcgagaccacatttgctgatgtaactgccgatggtgttggc tttgttccagcctgtactcttggggtgggacagaaagctcgtttgatttatggtcagaat gttgattccttaaagtggttcaccacatgtggtctgcaggaaggttacgagccattctgt gtaaatatgagacgtcctgtaacgcattggtataccaaggatcaaccaatttttgagaat actgaagattttatcgattgtcgcattgatgtaacgagaattccaggaggtgctgataca ccaccatgcttgaaaatctcccataacactttcgaaacgatggaaaaggccaattgggaa ttcctgaggctgtcactgccagttatttgtcaaagtgcatttattactgaaactgaaaaa atgcatcgctgggaagaaattaagatgcgccaaaatcgcattttggccgaagttgagcaa acaacaccagctcattttgaccacatcatgaggagtgggtttacgatgaatgacatcaaa ggtctgcataggaattacaatgaagacgctgcagaagctgatgaacagatgctccgaccc aatcctgctaggccaccacgcaaaggttctctatcgaggggtagtattgctccgtatgat ccaccaaccattgagatcaactccaagatccagaggtcaaccagtgaattggacatgaat gcttacggtgagattggtgagaaggatgacaagaagaagcgtggtcgtagtccattcaag ttcttttcgaagaagaatcgcgatcagagcaaggacaagttgaaggctaaaacaccagaa ccaggtgatcgcagaacgactagtactcaaggtcgcaatgtcattcagtctcaaaccatg actaggacacctactgtaagggtgtccaatgcggacttacgtgttcaaccgcctgcagtt ccagatcgtcccaaaaccatgaccgtcaacgcactcggcagcaacagtattgaatcggtt ggcaatgaagtttacgatgccgagtgtctcaaactaatcaatgagtacttctacggagtc cgaatcttccctggtcaagatcctacacatgtatggatcggttgggttaccacccaatac cacagacatagcaacgagtttaatcagcaaaccgttcgtcgagttgctgttgctatggaa gatgactacgaaactataatgggtcgggttaataggcagagttgctacatggttcgggct gatgaacttttcaatgaagtgactcaggatgcttcgggcaagggagcgtctcagggcatg tttgtaggatgcttcgttgatactgcaactggaacaattaggttcacatgcgaggggaag gagacatcgcacaaatgggtaatggaaccagataccaaactattcccagctatctttgtc gaagccacaagcaaggaagtacttcagattgaactgggtcgtaccccaactaccttaccc ttgtccgcagctgtactaccaacaggggacaagcatgttaatccacagttcccgcccagg ctcaaggtgcaatgcctcaagcctcatcaatgggctagggtgcccaacaatgctcttcaa gttcacgctttgaagctttccgacatcagaggctggtcgatgttgtgtgaagatccagta tctatgcttgctcttcatattcctgaagaagatcgctgtatagatattctggaactcatt gaaatggataaactcctttccttccattcccataccttgactctctatgcagctctctgc taccaatctaattacagagctgctcatgccctatgtcttcatgttgatcagaagcaacta ctctatgctattaagtctgagtacatgagtggtccactccgtcaaggattttatgacctt ctgattgcacttcatttggaatcgcatgccacaacaatggaggtatgcaagaacgagttt attattcctcttggaccagaattgacggaattgtacaaggaaacagaaatgtgccactcg ctcagatcacttcagaccgaatctgtaagacctcagatgaaaatgacagagattgcttcc ccaatgccgaatgtaccaatagtagtggccaatggtgtttccagtgagcctattccgacc atcgatgccctgtattcgccacgcttccctctggaaatagtccgggaatttgtaatggaa gctcttgctgaagctgttgaaatcaaccaagtgcacaaccgcgatccaataggtggatca aatgaaaacctcttcttgccactgatcaaactgtgcgatcgtcttcttcttgtgggaatt atgaaggatgaagacatagagaaactccttataatgatcgatccagaaacatgggatggt tcctttgacaaggaaggcaaggatgaacatcgaaagggtctcttgacaatgaagatggcc gaaggagctaagctccagatgtgctatctgttacatcatctatgtgatgttcagttgcgt catcgcgttgagagtatcattgccttctcaaatggcttcgttggagacctccaggctgat cagctgagacgttacattgagattaaacaatcagatcttccaagtgcagtggctgccaag aagactagagaattcagatgtccaccgagagagcaaatgaacgctattttgagtttcaaa gctcttgaagatgatgacattgaaaattgtccatgtggcgttgaacttcgtgatgccctc aacgagttccatggtcaacttatgactaaagtctccctaaatgctcttcaggactcagaa gaagatgattccggggcagcagataccggaaagaccggtccgctatctaaactcttcaat ttcatcaatactgtaaaggaattggaagaggaacctaaggaagcaattgaaccagttaag aagactcctgaagaaatattcaggaaggtcttgatcaagaccattgtatcatgggctgaa gagtctcagatcgaaactcccaaactcgtaagagagatgtttggtcttctcgtgaggcaa tacgatactgttggagagctaataaaagccctagagaaaacttatgtgatcaacagcaaa accaagaatgatgttgctggaatgtgggtgggattgagtcaaatccgagctctgcttccg gtgcaaatgagcgaagaagaagaaaagcttatgagaacgagactgtggaagttggttaac aatcacacattcttccagcatccagatttaatccggatcctaagagtgcatgagaacgtc atggccgttatgatgaataccctgggcagaagagctcaggcacagagcgatgctccagtt cagagtgaaggtggtgaggctcctgtgaaagaaaaggatacatctcatgagatggttgta gcttgctgccgtttcttgtgttacttctgccgaactagtcgtcaaaatcaaaaagctatg tttgatcactttgacttcctcttggagaactccaatattctcctatcccgaccaagtctt cgaggatctacccccttggacgtagcttattccagtttgatggagaatacagaattagct ctcgctttaagagagcattatcttgaaaagattgccgtatatctttcacgttgcggtcta cagagtaattcggaactcgtggagaagggttatccagatttgggatgggatcctgttgag ggtgagagatatttggacttcctacgcttctgtgtctgggtgaatggtgaaagcgttgag gagaacgctaacttggttattagactcctgattcgaagacctgaatgtctaggtccggcc ctacgtggtgaaggtgagggcctgctaagggcaattattgatgctaataaaatgtctgag agaatagccgatcgacgaaagcttcaagacgaggcagaaggaacaatggctggtcttaca tttaatcatcctctgccagaaagtgacgacgacgaagattatatagacactggagcagct atcctcaatttctactgtaccttggtagaccttctgggacgatgtgctccagataccgca gtgattgctcaaggaaagaatgagtctttgagagctcgtgctattctccgatctctagta ccgcttgaagatctgcaaggagtccttagcctcaaatttactttacaaaatccagctccg ggtgaagagaaacccaaatctgatatgccatccgggttgattccgggtcacaagcagagt attgtgatgttcttggaacgtgtatacggcattgaaacgcaggaactgttttacaaattg ctcgaagaagctttcctgccagatttacgagctgcaacgatgctcgataggaacgatgga tctgaaagcgacatggcgctgtctatgaatcgctacattggtaattcaatcttgcctttg ctcattcaacactcaaagttctacaacgaagcagaaaactatgccagtctcctggacgca actcttcacacagtgtatcgtttgtcgaagaacaggatgttaaccaagggtcagagagag gctgtttctgattttcttgtagctcttacagctcagatgcaaccgagtatgctgctgaag cttttgcgcaagttaaccgtagacgtatcccgtttgtcggaatatacaaccgttgcactt cgtctgctaacattacactatgatcgttgtgccaagtactatgggtcaagtggagggcag ggtgcttatgggtcttcttctgatgaggaaaaacgactcacaatgcttctgttctcgaat atctttgactccctcagcaatatggattacgatcctgagctgtttggcaaagccctacca tgccttattgccatcgggtgcgccttacctcccgattatagtttgtcgaagaatgcagat gaggacttttatggtaaaccctcatcagcagctgctcccgatcagccacagtacaatcct cagccaataaatacgagtgccgtggtattggacaatgatctgaattccattgtacagaaa ttcagtgaacactaccacgatgcttgggcgagtcgaaaacttgaggctggttggtcattc ggggagcaatggtcagacagccaaaagttccatcctcgactaaagccatacaatatgctg agtgattacgaaagggagcggtataaggagccagtcagggaggctcttaaggcacttctt gctcttggttggtctgttgaacatgccgaaggtgatgttcctctgtcacatcgaggatct accaggaggacgtcaaagccaaatcttgaatttcagactgactcttcatcaccattcaac tacaatcctcaaccaattgatatgaccaacttgacgctcagtcgagagatgcaaaatatg gctgagagaatagctgagaattctcacgatatttgggctaagaagaagcgagaagagttg aatacttgtggtggagctattcatccacagctcgtaccatatgatctgttgacagataag gagaagcgtaaggatagggaaagatcccaagaatttctcaaatacatgcaataccagggt tacaaacttcacaagccatcaagaggcatatccgctgatggggaacaagctggaggtggt ccagctattgaacttaggttcgcctactctctgcttgagaagttgattcaatacttagat agggcgaccatcaacatgaaattactgaagccttcgacaacatttagtcgtcgaaattcg ttcaaaaccagttccagagacatcaagttcttctccaaggtcgtgctaccgttaatggaa aagtacttctcaacccatcgtaactacttcattgcggtagcaacagcaactaacaacatt ggagcagcatcgcttaaggaaaaagaaatggttgctgctttattctgcaaacttgcaagt ttgctccgttatcgcttagctgcgttcggtccagatgttcgtatcacagttcgttgcctt caagttttggtcaagggtatcgatgcaaaatcactagtgaagaactgtcctgaattcatt agaacatccatgttgacgttcttcaacaacacagctgatgatcttggacaaactatattc aacttgcaggatggcaagtacagccatttaagaggaactcatctgaaaacttcaacttca ttagcctacgtcaatacggtcatattgccagttttgactgcaatgtttgatcatttggcc ggttgtgaatatggatcggacttgctcttggacgaaattcaagtggcttcctacaagatc ttatcatctctgtatacattgggtattgacgcaagcctaactcatgatagaaagtatctc aaaacggaaattgaacgtcacaaacctagtcttggttcctgcttaggtgccttcagttct acttttccagttgcctttttagaacctcatctgaataaacacaatcagttctcgttactc aatcgtattgctgaccattcactggaagctcaagatataatggccaagatggagaattcc atgccaacgcttgaggcaattcttcaagaagttgaccagtttgtcgagtccgataaaact tacaacgatgcgcaacatattattgacgttatactacctcttctgtgttcttacttgcct ttctggtgggctcaaggacctgacaacattacaccaacaactgggaatcacgtgacaatg gtaacagccgatcacatgaaccagttgctgaagaacgttttgaagatgatcaagaagaac atcggaaacgacaacgctcagtggatgacgagaattgctgcatacacgcaacagatcatc attaacagttccgaggaacttcttattgatcctttcctgccactggcagaacgcgtaagg aaacgcacggacaatatgttccacaaagaggagagtctcaggggtttcatcaaatccgca actgatgatacgtcgcaagttgaagcgcaaattcaggaggactggcaacttctcgtccga gatatctactcattctacccattgttgatcaaatatgttgatttgcagaggaaccactgg ctcaagaacaatattccagaagctgaagaattgtacaatcatgttgcagagattttcaac atctggtccaagagtcagtactttctgaaagaagagcagaacttcatatccgccaatgag attgacaacatggcccttattatgccaacagcaaccagaagaactcaggtcatctctgag ggtcaacagaatactggtggtaaaatcaaaaagaagaagaagaaccgagacaagaaacgt gataaggataaggaagtccaggccagtttgatggtggcctgtctgaaacgccttctgccc gttggattgaacctctttgctggtcgcgaacaagaacttgtgcagcactgcaaggatcgg tatttgaagaagatgtctgaagattttgtgattgagtttgcaagaactcagctaacactt cccgataagcttgatcctgctgacgaaatgtcctggcagcactacctctactccaagcta ggcaaaaaggaagtcgaagctgatgaaattgtggaaaaagccaaagtcacagatgagaag aagccagaaaacaagattgaagataccgttgatagaattgttgcaatggctaaggttctc tttggacttcacatggccaatcgcccaaagcaacgatctgacaagtggcagcgaattgta tccctggccaggagaaaatccgcacttgcttgtcttaaagctaaacccttgtacaagatg agcagacatcgggcttgcaatatatttgcacgaacgtaccacgaattgtggcttcaggag gagaatattggacaggaaattatgattgaggatctgacgcaatcattcgaggatgctgaa aaggccaagaaggatgccgaagaggaggagagcaaacctgatcctctgacccaactcgta accaccttctgccgtggtgccatgactgaacgtagcggagccctccaggaggatgcactg tacatgtcctatgctcagattgctgcaaagtcctgcggtgaggaagaagaggaaggtggt gaagaggagggtggtggagaagagggagaatcaagtggggcaagtattcataaaaacaca atggaaacccttatggaacaagagatggagaagcagaagttactattccaccaagcacgt ctgtcgaatcgaggagtagccgaaatggtccttctgcacatttcagcctcgaagggcgtt ccatctgatatggtcatgaagactcttgaactgggaattgctattctcaggggtggaaac attgacattcaaatgggaatgctgaatcatctcaaggagaagaaagatgttggcttcttc acttccattgctggccttatgaattcctgtagtgtattggatttggatgcatttgagaga aacactaaggctgaaggtttgggagttggagctgaaggagcagctggagagaaaaacatg cacgatgctgaatttacctgtgctctctttagatttatccaactaacatgcgaaggccat aacttagagtggcaaaattatctgaggactcaagcaggaaatacaacaactgttaacgtt gttatttgcactgtggattacttactgagactccaagaatccattatggacttctattgg cactattcgagcaaggaaatcattgacccagcgggtaaagcgaactttttcaaagccatt ggagtagctagtcaagtatttaacactctgactgaggtcatccaaggtccttgtacactc aatcaacaggctctggcacattcgcgattgtgggatgcagtgggtggttttctcttcctc ttctcccacatgcaagacaaactttccaagcattcgagtcaagtggatttgctaaaagag ttgctaaatctgcagaaagacatgataactatgatgctatccatgcttgagggtaatgtt gtcaatggaactattggtaaacagatggtggataccctcgtggaatcagcgtcaaacgtt gaattgatactcaaatacttcgacatgttcctgaaactcaaagacctaacttccacacca agctttcaggaaatcgatcccaacggagacggctggatcaatcctaaagatttccaggat aagatggaacaacagaaaagctatactccggaggaaatcgaattcctgttggcttgttgt gagagaaatcacgatggcaagatcgattatattgactttgtggatcgcttccacgatcca gctaaagagatcggttttaatttggcagtattactgaccaatttgtctgagcatatgccc aatgaaccgaggcttgctcgcttcctggagactgcaggatcggtcttgaactacttcgaa gccttcctgggtagaattgaaatcatgggcagttccaagagaattgagagagtctacttt gagataaaggagtccaacatcgagcaatgggagaaaccgcagatcaaggagtccaagaga gccttcttctattcaattgtaactgaaggcggtgacaaggagaagctggaagctttcgtc aacttctgcgaagatgcgatctttgaaatgacccatgcttctgccctaatggccactgat gaaggtggtggtaatgtaagaagagaggcttccttcagcacttacataagcgaagaggaa gaagaaaaggcagctaaggatcccatcaagagaacagtgcaaggggtaaaggatggcttc tggttcatattgcacctcttcagtgtgtccaacatcaagcaccaaatagcggtagcacaa actaaatccgtacccgaactgttcattggcttcttcaagatgatcttctacgctttctac tattctggcctcggagtgacactgatcatcaagtacttcctgaacatcctgatgtccttg atgcgcggatctggaactgaggaaattgaagcaccgcctgaacctgaagcatcgggactg atgagagccttaccggctcttccgcaagaggaacctcctggtacagttcaggcattcgga ctggatataagtaaagaagagaatgggcagtataagttggcaccacatgaatctcccgca gcaagtccatcttcgtcaatggaagagacaggagagagtagtcctgaagatgccgctgca gctggagaacatggacctgaggaaggtcaggaaccaccaataacccttgtagatctccta ggtggtgaagctgctaagagagctgcacaggaacgttctgaagctcagaagcttcaggaa gctgcaatggccaccattgaggctgaaacgaagaaatcctcagcagaaccaaaagaacca gcagctgtgacgcaaattgacttctctcagtacacccacaaaattgtcagcttcctggca cgaaatttctacaatctcaaatacgtggctcttgtcttggctttctgcatcaactttatg ctgctcttctacaaagtgacaacctttggtgaggatgagggaggttctggcgaaggagaa ctggacttaggatttggatcaggtggatcgggatcgggtttgggtgcaattctcgaaggt agtgcaaatggagaaggtgaagaaggcgaagaagaagatcccctggaatcagttcacgta gatgaagatttctactacatggaacacgtactaaggatagctgctcttcttcacagtacg gtatctctggctatgcttatcgcctactaccatcttaaggttccccttgcgatcttcaag cgcgagaaggaaattgctcgtcgcttggaatttgatggactcttcattgccgaacagcct gaagatgatgacatcaagtctcactgggataagcttgtgatatcggccaaatctttcccc gtcaactactgggataagtttgtaaagaagaaagtgcgtcagaagtatagcgaaacgtac gacttcgaatcaatatccaatcttctgggcatggaaaagtcagcatttacgactcaagaa acagaaggtggtggtttggttcattacatcgttaacatagattggcgctatcagatttgg aaagccggcgtgacaatcacagacaatgccttcctgtactctctttggtactttacattt tctatctttggaaatttcaacaatttcttctttgccgcccatttgctggacgtagctgtt ggtttcaagaccctgcgaaccatcttgcaatctgtcacgcacaatggcaagcaacttgta ctcacagtgatgctactcacgatcatcgtgtacatctacacggtgatcgccttcaatttc ttccgcaagttctatgttcaagaggaagatgaagaagtggacaagaagtgccatgacatg ctaacgtgcttcgtgttccatctgtacaagggcgtgagagctggtggtggaataggtgat gagataggtgatccagatggcgatgactacgaagtataccgcatcatcttcgacatcacc ttcttcttcttcgtcattgtcatcctgttggccatcattcagggtctcattattgacgcc tttggtgaactccgtgatcaactggagtctgtgaaggaagatatggagtccaattgcttc atatgcggtatagggaaggactactttgataaagtaccgcatggcttcgatactcacgtc cagcaggagcacaacctggcaaactacatgttcttcctcatgcatctcatcaacaaacca gacaccgagtatactggccaggaaacgtacgtctggaatatgtatcagcagagatgctgg gacttcttccccgttggtgattgctttaggaagcaatacgaggaagaattgggtggcgga agtggcggttaa

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