KEGG   Phlebotomus papatasi: 129807149
Entry
129807149         CDS       T10447                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ppap  Phlebotomus papatasi
Pathway
ppap00562  Inositol phosphate metabolism
ppap01100  Metabolic pathways
ppap04070  Phosphatidylinositol signaling system
ppap04081  Hormone signaling
ppap04082  Neuroactive ligand signaling
ppap04310  Wnt signaling pathway
ppap04745  Phototransduction - fly
Module
ppap_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ppap00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    129807149
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    129807149
   04070 Phosphatidylinositol signaling system
    129807149
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    129807149
   04081 Hormone signaling
    129807149
 09150 Organismal Systems
  09157 Sensory system
   04745 Phototransduction - fly
    129807149
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ppap04131]
    129807149
Enzymes [BR:ppap01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     129807149
Membrane trafficking [BR:ppap04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    129807149
 Endocytosis
  Macropinocytosis
   Phospholipase C
    129807149
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 EF-hand_15 PLC-beta_C CBP66_1st DUF2420
Other DBs
NCBI-GeneID: 129807149
NCBI-ProteinID: XP_055712184
LinkDB
Position
3:complement(63146798..63351406)
AA seq 1322 aa
MASSALSTVAGPAAAAVAVAVPPDSQKQQQQKDQSPRNTASLSASPTVGGNATAYVQLGA
IEVSKALQEGEKFIKWDEDSGSGTPVTLRVDAKGFYLYWVDQNNEMDLLDIATVRDVRTA
QYAKKPRDTKLRQIVTMGSQDTLEEKTVSVCYGADFVNVTFINFCCTRKDIAQHWSEELM
RLAFNMTQLNGSAVMYLQKAHTKLCLQMDKSGKIPVKNIVKLFAVNKDDRRRVEKAMDIS
GFPSGKGESLLPNKFQFEDFFNLYKNLTQRTELEKIFEELSSSGTTKRRLMSTTQLVDFL
NKTQRDPRLNEILHPYANPARAKDLIAEYEPNKFNAQKGLLSFDGFLRYLMSEDNPIMAP
TKLDICDDMDQPLSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLSGCRCVELDFWNGKL
EEPVIVHGYTFVPEITAKDVLEAIAESAFKTSDYPVILSFENHCNTKQQAKIANYCRDIF
GDMLLDKCLDSHPLEPNVELPPPSMLKRKIIIKNKKKHHHHHHHHYKKTAAAVAAAAAGA
AANSGATNQNNVLSPGSATGGIGSDEMLQAVPTTSTVPTGNGDLPHHAPPLQQIRQSSKE
STGSSDTDSSSDDESMPGSTANAPGGAEQRDKVQQAKETEAGAEISALVNYVQPVHFSSF
ENSEKKNRYYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFW
NAGCQLVALNYQTLDLAMQLNQGIFEYNHRCGYLLKPEFMRRTDRRLDPFAESTVDGIIA
GTVSITVLSGQFLSDKKVGTYVEVDMYGLPADTVRKKFRTKIVRDNGINPVYDEEPFVFK
KVVLPELACVRITAYEEGGKFIGHRVLPVIGLCPGFRHLALRTELGQPLGLASLFLCIVV
KDYVPDGLSDFAEALANPIKYQSELEKRAEQLAVLTEDMEPTAEDDVPNSCPKKELKVCE
GVSGSPKHRISIAPSASLSVEILADGDSDVSFNTSAASGSLQVTSATAVSSTSVSSSVIQ
QTSIDQSISSSSKSAEATEADAIVAEPLGKILEHKLIREKRAEMEKKLESLRKKHDKEKV
RVSAQKSSEQSDKKSKFYMSNKLVKRLSSKNISDTNLQVPPCPSDILESPDGEGEERAGI
TRSHSERLLAVCREYATAYREIQEKYHEIIYSTAEKVLRNSQANQMKRLRTLLEKETSEV
MRKLQMDRRNEVKALALVHRDRDELVRMKREVASSLVGRGVTERVRLTQAFEKRRDELQR
QHDAVRNALAEHRAKAKAFLEKESESRSCISSDGFLVLFNASGAENSQTSSNNSAGMHIE
SL
NT seq 3969 nt   +upstreamnt  +downstreamnt
atggcatcgtcggctctgtcaacagtcgcgggaccagcggctgccgctgtggcagttgct
gtaccgccagacagtcagaagcagcagcagcagaaggatcaaagtcccaggaatacggcc
tcactgtcggcctcgccgacagtgggcgggaatgccacagcatacgtccaattgggtgcc
attgaggtgtccaaagcactacaggagggcgaaaagttcatcaagtgggatgaggattct
gggtctggtacaccagtcacattgcgggtggatgcaaagggattttatttgtattgggtg
gatcaaaacaatgaaatggatcttctcgatatcgcgactgtaagagatgtgaggacagca
caatatgccaagaagccgagggatacaaaattgcgccaaatcgtcacgatgggttcacag
gatacactggaggagaaaacagtgtctgtttgctatggtgcggattttgtaaacgtgaca
tttatcaatttctgctgcacacgaaaagatattgcacagcactggtcagaggaattgatg
cgattggccttcaatatgactcaactgaatggatcggctgtcatgtatctgcaaaaggct
cataccaaactctgtctccaaatggataaatctggcaagattcccgtaaagaacatcgtg
aagttgtttgctgtgaataaagatgacaggagacgtgtggaaaaagcaatggatatatcg
gggttcccttctggcaagggtgaatctctcctgcccaataaatttcaatttgaagacttt
ttcaatctctacaaaaatctgacgcagcgcactgaattggagaagatatttgaagaactc
agcagttctggcacgactaaaaggcgactgatgtccactactcagttggttgactttctc
aataaaactcagcgtgatccacgcctcaatgagattctccatccatatgcaaatcccgcg
agagccaaagacttgattgctgaatatgagccaaataaatttaatgcccagaagggtctc
ctgagctttgatggtttcctgaggtacttaatgtctgaggataatccaattatggcacca
actaaattggacatttgcgatgatatggatcaacctctatcgcactattttatcaattcc
tcccataatacctatctcactggacatcaattgactggaaagagttctgttgagatctat
cggcagtgtttactgtctggctgcaggtgtgttgaattggacttttggaatggtaaactc
gaggagcctgttattgttcatggatatacgtttgttcctgaaattacggcgaaagatgta
ctggaagcaatagctgaaagtgcatttaaaacttcagactatcctgtgatattaagtttt
gaaaatcattgcaatactaaacaacaagccaaaatagcaaattactgtcgggatatcttt
ggtgatatgttgctagataaatgcctggattctcatccgttggagccaaatgttgaacta
cctccaccgtcgatgctgaagcgtaagataatcataaagaataagaagaagcaccatcac
catcatcatcatcattataagaagaccgctgcagctgtagcagcagcagcggctggtgca
gctgcaaattctggtgccacgaatcaaaataatgtcctgtcaccaggcagtgcaacaggt
ggcatcgggagcgatgagatgctacaggcagtaccgacaacttccactgtacccaccgga
aatggagacttaccccatcatgcaccaccacttcagcaaatacgccagagttccaaggaa
agcaccggttcttcggatacagacagctctagcgatgatgaatctatgcctggatctacg
gcaaatgctccaggtggtgctgaacagagggataaagtacaacaagcaaaagagactgaa
gctggtgctgagatatcagcactcgttaattatgttcaaccggtgcactttagcagtttt
gaaaattctgaaaaaaaaaatcgttactatgagatgtcatcgtttgatgagaagcaagct
acaacattactgaaggagcgtccaattgagtttgtgaactacaacaaacaccaattgtct
cgggtgtatccagctggaacacgcttcgatagttccaacttcatgccgcagcttttttgg
aatgccggctgccagctggtggctctcaactaccaaactctcgatctggccatgcagctc
aatcagggcattttcgagtacaatcaccgatgtgggtacctgttgaagccggagtttatg
cgcagaacagataggcgtctcgatcccttcgccgagagcactgttgatggtatcatagct
ggcacggtgtcgataacagtgctgtctggtcaatttctcagtgacaagaaggtgggaaca
tacgttgaggtggatatgtatggtttaccggcggacactgtgaggaaaaagtttcgcaca
aaaatagtccgagacaatggaattaatcctgtctacgatgaggagccatttgtcttcaaa
aaggttgttcttcccgaattggcgtgcgttcggatcactgcatacgaagaggggggtaaa
tttattggtcatcgtgttcttcctgtcatagggctatgtccgggatttcgtcatttggct
cttcggactgaattgggtcaaccactcggcttggcttctctatttctctgcattgttgtt
aaggattatgttccagatggattatcggactttgctgaggctcttgctaatccaattaag
tatcagagtgaattggagaaacgcgctgaacagttggctgttttgacggaagatatggag
cccacagcagaggatgatgttccaaatagttgtcccaagaaagagcttaaagtgtgcgaa
ggtgtttctgggagtccaaaacatcggatcagcattgcaccatctgcatcattgagtgtt
gaaatactcgctgatggggattccgatgtctccttcaatacctcagcggcaagtggaagt
ttacaggtgacgagtgcaactgctgtgtccagcacaagtgtttcctcatctgtgatccaa
cagacttcgatagatcagtcaatatcgagttccagtaaatctgctgaagctacagaagct
gatgcaattgtggctgaaccattgggaaagatcctggaacacaaattgatacgggaaaag
cgggctgagatggagaaaaaattggaaagtctgcggaagaagcatgacaaggaaaaagta
cgagtgtcagcacagaaaagcagtgaacagagtgacaaaaagtcgaaattctacatgagc
aataaactcgtaaagcgtctgagcagcaaaaatataagtgatacgaatcttcaggttcct
ccctgtcccagtgatattttggagtctccagatggtgagggtgaggaacgtgcaggaata
acaaggagtcactcggagagattgctggccgtttgccgagaatatgccactgcctataga
gaaattcaggagaagtaccatgagataatctacagtactgctgagaaagttctgagaaat
tcccaggcaaatcaaatgaaacgtctcaggacgctgctggagaaggagacgagcgaggtg
atgcggaagttgcagatggatcgacggaatgaggtgaaagccctggccctggtgcatcgt
gatcgggatgaattggtgcgaatgaagcgggaggtggcgtcatcgttagtgggcaggggt
gttactgaacgtgtacgtctgacccaggcctttgagaagcgtcgtgatgagctgcagcgt
cagcatgatgctgtgagaaatgctctggctgagcacagagccaaggctaaagccttcctg
gagaaggaatcggaatctcgttcgtgtatctcatcggatggatttttggtattgtttaat
gcgtctggcgcagaaaatagtcaaacatcttccaataatagtgcaggaatgcacattgaa
tctctctaa

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