KEGG   Phocoena phocoena (harbor porpoise): 136118633
Entry
136118633         CDS       T11058                                 
Symbol
EGLN3
Name
(RefSeq) prolyl hydroxylase EGLN3 isoform X1
  KO
K09592  hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc04066  HIF-1 signaling pathway
pphc05200  Pathways in cancer
pphc05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    136118633 (EGLN3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136118633 (EGLN3)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    136118633 (EGLN3)
Enzymes [BR:pphc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.29  hypoxia-inducible factor-proline dioxygenase
     136118633 (EGLN3)
SSDB
Motif
Pfam: 2OG-FeII_Oxy_3 2OG-FeII_Oxy_4
Other DBs
NCBI-GeneID: 136118633
NCBI-ProteinID: XP_065727941
LinkDB
Position
2:64292792..64320573
AA seq 239 aa
MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCNGALRDGQ
LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA
MVACYPGNGTGYVRHVDNPSGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFIADVEP
IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTEPALTED
NT seq 720 nt   +upstreamnt  +downstreamnt
atgcccctaggacatatcatgaggctggatctggagaagatcgccctggagtacatcgtg
ccctgtctgcacgaggtcggcttctgctacctggacaacttcctgggcgaggtggtgggt
gactgtgtcctggagcgagtcaagcagctgcactgcaacggggccctgcgggacggccag
ctggccgggccccgcgccggcgtctccaagcggcacctgcggggcgaccagatcacgtgg
atcgggggcaacgaggaaggctgcgaggccatcagcttcctcttgtccctcatcgacagg
ctggtcctgtattgcggcagccggctgggcaaatactacgtcaaggaaaggtccaaggcg
atggtggcttgctacccaggaaatggaacaggttatgttcgacatgtggacaaccccagc
ggtgacggccgctgcatcacctgcatctactatctgaacaagaactgggatgccaagcta
catggtggggtcctgcggatatttccagaagggaaatcgttcatagcggatgtggagccc
atttttgacagactcttgttcttctggtcagaccgcaggaacccacatgaagtccagcct
tcctatgcaaccagatatgccatgactgtttggtactttgatgccgaagaaagggcagaa
gccaaaaagaaattcaggaatttaactaggaaaactgaacctgccctcactgaggactga

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