Phocoena phocoena (harbor porpoise): 136121704
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Entry
136121704 CDS
T11058
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04217
Necroptosis
pphc04380
Osteoclast differentiation
pphc04620
Toll-like receptor signaling pathway
pphc04621
NOD-like receptor signaling pathway
pphc04630
JAK-STAT signaling pathway
pphc04658
Th1 and Th2 cell differentiation
pphc04659
Th17 cell differentiation
pphc05145
Toxoplasmosis
pphc05160
Hepatitis C
pphc05161
Hepatitis B
pphc05162
Measles
pphc05164
Influenza A
pphc05165
Human papillomavirus infection
pphc05167
Kaposi sarcoma-associated herpesvirus infection
pphc05168
Herpes simplex virus 1 infection
pphc05169
Epstein-Barr virus infection
pphc05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
136121704 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
136121704 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
136121704 (TYK2)
04621 NOD-like receptor signaling pathway
136121704 (TYK2)
04658 Th1 and Th2 cell differentiation
136121704 (TYK2)
04659 Th17 cell differentiation
136121704 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
136121704 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
136121704 (TYK2)
05160 Hepatitis C
136121704 (TYK2)
05171 Coronavirus disease - COVID-19
136121704 (TYK2)
05164 Influenza A
136121704 (TYK2)
05162 Measles
136121704 (TYK2)
05168 Herpes simplex virus 1 infection
136121704 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
136121704 (TYK2)
05169 Epstein-Barr virus infection
136121704 (TYK2)
05165 Human papillomavirus infection
136121704 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
136121704 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pphc01001
]
136121704 (TYK2)
Enzymes [BR:
pphc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
136121704 (TYK2)
Protein kinases [BR:
pphc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
136121704 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
136121704
NCBI-ProteinID:
XP_065731733
LinkDB
All DBs
Position
3:166352804..166371577
Genome browser
AA seq
1208 aa
AA seq
DB search
MPLCQWGATTRGRKPDGDGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCLH
IAHKVGITPPCFNLFALFNVQAQVWLPPNHVLDMSRDSSLLLYFRMRFYFRNWHGMHPQE
PAVYRCGPPGSEPSSEQAKQGVQLLDPASFEYLFEQGKHEFINDVASLWELSSEEEIHHF
QNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPHSFRQQIRQHNALTRLRLRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPHFGTERVPVCHLELLAQAEGEPCYIRDGGQA
PPDPGPESAAGPPTHEVLVSGTDGIQWRLVQAEVSGADGGGGGGRRMPHAGPSGKKAKAQ
EVGNQPVHRPQEAPWAYFCDFQDITHVVLKERRVSIHRQDNKCLELTLPSQAAALSLVSL
VDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLARLQPEDGLYLIHWSTSH
LHRLILTVAQRDQAPGVKGLHLRKFPIELQAGTVALEGWDRSFPSVRELRVALQGCSLRA
GDDCFSLRHCCLPRPGEISNLIVTRGPRASSRPLNLSHLSFHQIRQEDITQLSHLGQGTR
TNVYEGLLRVGGGGPEEDKVDGGDPPMPGAGCEQELRVVLKVLDPSHHDIALAFYETASL
MSQVSHVHLVFVHGIYVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLASA
LSYLEDKSLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSVLSREERVERIPWTAP
ECLSGGANSLSTAADKWGFGATLLEIYFDGEAPLQGRSPSEKERFYQKQQKLPEPSCPEL
AILTSQCLTYEPAQRPSFRTILRDLTQLQPQSEHHSRAGTLEGGRDSPTVALPDLVDVLS
VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQ
LRTGWRREIEILRTLYHQHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQ
LLLFSQQICEGMAYLHAQHYVHRDLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVRE
DGDSPVFWYAPECLKECKFYYASDVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQM
TVLRLTELLERGERLPQPEKCPCEIYCLMKNCWKAEASFRPTFQNLIPILKTVHEKYQGQ
AASVFSVC
NT seq
3627 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggggggccaccaccaggggcagaaagcccgatggggatggagct
cagcccatggccaccagaggaggcctgaaggtgcttctgcactgggctggccccggtggc
ggggagccctgggtcaccttcagcgaggccacactgactgcggaggaggtctgcctccac
attgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcaatgtc
caggcccaggtctggctgcctccaaaccacgtcctggatatgtccagagactcgagcctg
ttgctgtacttccgcatgaggttttatttccggaactggcatggcatgcatccccaggag
ccggctgtgtaccgctgtggtcccccagggtccgagccttcctcagaacaggccaagcag
ggggtgcaactcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
ttcataaatgacgtggcatcgctgtgggagctgtcaagcgaggaggagatccaccacttt
cagaacgagagcctgggcatggcctttttgcacctctgccacctcgctctctgccatggt
gtcccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccacactccttc
cggcagcagatccgacagcacaatgctctgacgcggctgcgcctgcggagcatcttccgc
aagttcctgcgggccttccagccaggctgcctctcccagcaggttgtcatggtgaagtac
ctggccacactcgagcggctggcgccccacttcggcacagagcgcgtgcccgtgtgccac
ctggagctactggcccaggccgagggggagccctgctacatccgggatggcggacaggcc
cctcccgaccctgggcccgagtctgccgcaggaccccccactcacgaggtgctggtgtcg
ggcaccgatggcatccagtggcggctggtacaggcagaggtgagcggggctgatggtggt
ggtggtggtggcagaaggatgccccatgctggcccatctgggaagaaagccaaggcccag
gaagtgggcaaccagccagtgcacagacctcaggaggccccatgggcctacttctgcgac
ttccaggacattacccacgtggtgctgaaagaacgccgcgtcagcattcatcgtcaggac
aacaagtgcctggagttgaccctgccttcccaggctgcagccctgtccttggtgtcactg
gtggatggctacttccgcctgacggccgactcgagccactacctatgccatgaggtggct
cctccacggctggtgatgagtatccaggacggtatccacggacccctgctggagccattt
gtgctggccaggctgcagcccgaggacggcctttacctcatccactggagcaccagccac
ctccaccgccttatcctcacggtggcccagcgtgaccaggcacccggcgtgaagggcttg
cacctacggaagttccccatcgagttgcaggctgggactgtcgcgctggagggctgggac
cggtccttccccagcgtgcgcgagctgcgggttgccctccagggctgctccctgcgggcc
ggcgatgactgcttttccctgcgccactgctgcctgccacggccaggagagatctccaac
ctcatcgtcacgcggggacctcgggccagcagcaggccactcaacctcagccatctcagc
ttccaccagatccgccaggaagacatcacccagctatcccacttgggccagggcacgagg
accaatgtgtatgagggcctcttgcgagtggggggcggaggccctgaagaggacaaggtg
gatggtggggacccccccatgcccggggcgggctgtgaacaggagctgcgagtggtactc
aaggtgctagatcccagtcaccatgacatcgccctggccttctacgagacagccagcctc
atgagccaggtctcccacgtgcacctggtcttcgtgcacggcatctacgtgcacggctcc
gagaatatcatggtgacggagtacgtggaacacgggcccctggacgtgtggctgcggcgg
gagaggggccgcgtgcccctggcctggaagctggcagtggcccagcagctggccagcgcc
ctcagctacctggaagacaagagcctggttcacagcaacgtgtgtggccggaacatcctc
ctggcacggctggggctggcggagggcaccagccccttcatcaagctgagtgaccccggt
gtgggcctgagcgtcctctccagggaggaacgggtggagcggatcccctggacagcccct
gagtgcctgtccggtggagccaacagcctaagcactgcagccgacaagtggggctttggt
gccaccctcctggagatctacttcgatggggaggcccccctgcagggccgcagcccctcc
gagaaagagcgcttctaccagaagcagcagaagctgcctgagccctcgtgcccagagctg
gccatactcaccagccagtgcctgacctatgagccagcccagcggccatccttccgcacc
atcctgcgtgacctcactcagctgcagccccaaagtgagcatcactccagggcggggacc
ctggagggggggagggactcacccactgtagctcttccagatctcgttgatgtcttgtct
gtgaacccggactcaccggcgtcagatcctacggttttccacaagcgctatttgaaaaag
atcagggatctgggtgagggtcacttcggaaaggtcagcctgtactgctacgatccaacc
aatgacggcactggtgagatggtggccgtgaaggccctcaaggcaggctgcggtccccag
ctccgtacaggctggaggcgagagatcgaaatcttgcgcacactctaccaccagcacatt
gtcaagtacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggag
tacgtgcccctgggcagcctccgagactacttgcctcggcacaatgtcgggctggcccag
ctgctgctcttctcccagcagatctgcgagggtatggcctacctgcacgcgcagcactac
gtgcaccgagacctggccgcacgcaacgtgctgctggacaacaacagactggtcaagatt
ggggacttcggtctcgccaaggccgtgcccgaaggccatgagtactactgtgtgcgcgag
gatggggacagtcccgtgttctggtatgccccggagtgcctgaaggagtgtaagttctac
tatgcatccgacgtctggtcctttggggtcaccatgtatgagctgctgacctactgtgac
tccacccagagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg
acagtgctgaggctcactgagctgctggaacgaggagagaggctgccacagccagagaaa
tgtccctgtgagatctattgcctcatgaagaactgctggaaagcagaggcctcattccgc
ccgaccttccagaacctcatacccatcctcaaaacggtccacgagaaataccaaggtcag
gcagcctcagtgttcagtgtctgctga
DBGET
integrated database retrieval system
