Phocoena phocoena (harbor porpoise): 136122199
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Entry
136122199 CDS
T11058
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00230
Purine metabolism
pphc00670
One carbon pool by folate
pphc01100
Metabolic pathways
pphc01523
Antifolate resistance
Module
pphc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
136122199 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
136122199 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
136122199 (GART)
Enzymes [BR:
pphc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
136122199 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
136122199 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
136122199 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
DUF498
ATP-grasp_4
Dala_Dala_lig_C
LUD_dom
RimK
SNF5
Motif
Other DBs
NCBI-GeneID:
136122199
NCBI-ProteinID:
XP_065732147
LinkDB
All DBs
Position
4:complement(135175388..135198639)
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSNHVKQVLVTPGNAGTACSEKISNTDISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKAEEACCFIMSADFPALVVKASGLAAGKGVVVAKNKEEACKAVQEIMQDKAF
GEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVSKDLLLEIKNTILQKTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
IGYHAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDPSTTEAVVAGIATACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTQQILQDIQQHKEEAWAIGRVVACPEGSPRVKVKH
LIETMQINRSVLENGTLKNHVSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHIVVV
ISNTAAVSGLDKAERAGIPTRVINHKLYKNRVAFDTTVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVETLSERVKLAEHKIFPSALQLVASGTVRLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagggaacatactctggcctggaaa
cttgcacagtctaatcatgtcaaacaagtgttagttaccccaggaaatgcaggcactgcc
tgctctgaaaagatttcgaacactgacatctcaatcagtgatcacactgcccttgcacag
ttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacctctggctgct
ggaattgttgggagcctgacatctgcaggagtgcggtgctttggccctacagcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacagtggagagctttcaccaaagctgaagaagcctgctgcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtagttgtc
gcaaagaacaaagaagaggcctgcaaagctgtacaggagattatgcaggataaagctttt
ggagaagctggagaaacaactgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaagactgtggcccctatgcccccagcacaggaccataagcga
ttgctggagggagatcagggccccaacacagggggaatgggagcctattgtccagcacct
caggtttctaaggatttgttgctagaaattaaaaatactattcttcagaagacagtggat
ggcatgcagcaggagggtgtgccatacacaggtatcctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttagatggcctg
ctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtggtcatggca
agtaaaggttatccaggagactacaccaaaggtgtagagataacagggtttcctgaggct
caagctttaggactagaggtgttccaagcaggcactgccctaaaagatggcaaagtggtg
actaacgggggtagggtccttacagtaacggccatccgggaaaatctcatctcagccctt
gaagaagccaagaaaggactagctgctataaagtttgagggggccatttataggaaggac
attggctatcatgccatagctttcctccagcagcccaggggcctgacttacaaggactct
ggggtagatattgcagctggaaatatgctggtcaagaaaattaagcctttagcaaaagcc
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggtttcaacgatcctcttctggcctgtggaacagacggcgttggaactaaactg
aagattgcccaacagtgccataaacatgaaaccattggtcaagatttggttgcgatgtgt
gtaaatgatattctggcacaaggagcggagcccctctttttcctcgattacttttcctgt
ggaaaacttgaccccagtacaactgaagctgttgttgctggaatcgctacagcttgtaaa
aaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatgtaccctcct
ggagagtatgatctagccggttttgccgttggtgcaatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggacgctgttattggaatagcttcatctggtcttcac
agcaatggatttagccttgtgaggaaaattgtagcgaaatcttcccttcagtactcctct
ccagcacctgatggctgtggtggccaggccttaggtgatttacttctaactccaaccaga
atctacagccattcactgttacctgtcctgcgttcaggacatgttaaggcctttgcacat
attaccggtgggggattgctagaaaacatccccagagtcctgcctcagaaatttggggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggatctgacacagcagattctgcaggatattcagcagcacaaggaagaagcc
tgggcgatcggcagagtggtcgcatgtcctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcagataaatagatcagtgttggagaatggcaccctgaaaaatcat
gtctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggacaggatcaaac
ctccaagctctcatagacagcactagggagccaagtagctctgcacacattgttgttgtg
atctccaacacagctgcagtgtctggcttagataaagcagaaagagccggaattcccacc
agagtaattaatcataaattatataaaaatcgtgtagcatttgacactacagtagaccaa
gtccttgaagagttctccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatccttgctccct
tcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcaccgtcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaattagcagaa
cataaaatatttccctcagccctccagctggtggccagtggaactgtacggcttggagaa
aatggcaagatctgttgggtcaaagaggaatga
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