Phocoena phocoena (harbor porpoise): 136123093
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Entry
136123093 CDS
T11058
Symbol
HPSE
Name
(RefSeq) heparanase isoform X1
KO
K07964
heparanase [EC:
3.2.1.166
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00531
Glycosaminoglycan degradation
pphc01100
Metabolic pathways
pphc05205
Proteoglycans in cancer
Module
pphc_M00078
Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
136123093 (HPSE)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
136123093 (HPSE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
pphc00536
]
136123093 (HPSE)
Enzymes [BR:
pphc01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.166 heparanase
136123093 (HPSE)
Glycosaminoglycan binding proteins [BR:
pphc00536
]
Heparan sulfate / Heparin
Enzymes
136123093 (HPSE)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
136123093
NCBI-ProteinID:
XP_065733232
LinkDB
All DBs
Position
5:40117580..40149827
Genome browser
AA seq
542 aa
AA seq
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MLLSWKPGLPLRLLLLLGPLCPCSPGALAELAPAEDVVVLVFSTERPVHLVSPAFLSFTI
DANLATDPRFLTFLGSSKLRTLARGLSPAYLRFGGTKTDFLIFDPKKEPTFEERSYWQSQ
VNQDICESGSVPSDVERRLKLEWPFQEQLLLREQYQKKFKNSTYSRSSVDMLYTFASCSG
LDLIFGLNALLRTADLHWNSSNAQLLLDYCSSKSYNISWELGNEPNSFRKKAGIFIDGLQ
LGEDFMELHKLLGKSAFKNAKLYGPDVGQPRGKTVKMLKSFLKAGGEVIDSVTWHHYYLN
GRIATKEDFLNPDVLDTFISSVQKIFQAVEETRPHKKVWLGETSSAYGGGAPLLSNTFAA
GFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFEPLPDYWLSLLFKKLVGTNVLMA
SVKGPDRNKLRVYLHCTNINHPRYKEGDLTLYALNLHNVTKRLQLPHHLFDKQVDKYLIK
PSGPNGLFSKSVQLNGQTLKMVDDQTLPALTEKPLRPGSSLGLPALSYGFFVIRNAKVAA
CI
NT seq
1629 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgagctggaagcccgggctgccgctgcggctgctgctgctcctggggccgctg
tgtccctgctccccgggcgccctggcggaactcgcgccagctgaggacgtcgtggtgctg
gttttctccaccgagcggccagtgcatctggtgagtcccgcgttcctgtccttcaccatc
gacgccaatctggccacggacccgcggttcctcaccttcctgggttcttcaaagcttcgt
actttggccagaggtttgtctcccgcatacctgagatttggtggcacgaagacggacttt
ctcatttttgatcccaagaaggaaccaacctttgaagagagaagttactggcaatctcaa
gtcaaccaggatatttgcgaatctggatccgtcccttctgatgtggagaggaggttgaag
ttggaatggcccttccaggagcaattgctactcagagaacagtatcagaaaaagttcaag
aacagtacctactcaagaagctcagtggatatgctgtatacttttgccagttgctcagga
ctggacctgatctttggtctaaatgcattactacgaactgcagatttgcactggaacagt
tccaatgctcagttactcctggactactgctcttccaagagttataacatttcttgggaa
ctaggcaatgaacctaacagtttccggaagaaggctggtattttcatcgatggattgcag
ttaggagaagattttatggagttgcataaacttctaggaaaatctgctttcaaaaatgca
aaactctatggtcctgatgttggccagcctcgaggaaagactgttaagatgctgaagagt
ttcttgaaggctgggggagaagtgattgattcagttacatggcatcactactacttgaat
gggcgaattgctaccaaagaagattttctaaaccctgatgtactggacacttttatttca
tctgtgcaaaaaattttccaggctgttgaggagaccagaccccacaagaaggtttggtta
ggagagaccagctctgcgtatgggggtggagcacccttgctgtccaacacctttgctgct
ggctttatgtggctggataaattgggcctgtcggccagaatgggcatagaagtggtgatg
aggcaagtgttcttcggagctggaaactaccatttagtggatgaaaattttgaacctttg
cctgattattggctctctcttctgttcaagaaactggtgggcaccaatgtgttaatggca
agtgtgaaaggtccagacagaaacaaacttcgagtatatcttcattgcacaaacatcaac
cacccaaggtataaagaaggagatttaactctgtatgccttaaacctccataatgtcacc
aagcgcttgcagttaccacatcacttatttgacaagcaagtggacaaatacctcataaaa
ccttcaggacccaatggcttattttccaaatctgtccagctcaatggtcaaactctgaag
atggtggatgaccaaaccctgccagctttgacagaaaaacctctccgcccaggaagttca
ctgggcctgccagctctctcatatggattttttgtgataagaaatgccaaagttgctgct
tgcatctga
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