Phocoena phocoena (harbor porpoise): 136123211 Help Entry 136123211         CDS       T11058                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism pphc  Phocoena phocoena (harbor porpoise) Pathway pphc01521   EGFR tyrosine kinase inhibitor resistance pphc04151   PI3K-Akt signaling pathway pphc04217   Necroptosis pphc04380   Osteoclast differentiation pphc04550   Signaling pathways regulating pluripotency of stem cells pphc04620   Toll-like receptor signaling pathway pphc04621   NOD-like receptor signaling pathway pphc04630   JAK-STAT signaling pathway pphc04658   Th1 and Th2 cell differentiation pphc04659   Th17 cell differentiation pphc05140   Leishmaniasis pphc05145   Toxoplasmosis pphc05152   Tuberculosis pphc05160   Hepatitis C pphc05161   Hepatitis B pphc05162   Measles pphc05163   Human cytomegalovirus infection pphc05164   Influenza A pphc05165   Human papillomavirus infection pphc05166   Human T-cell leukemia virus 1 infection pphc05167   Kaposi sarcoma-associated herpesvirus infection pphc05168   Herpes simplex virus 1 infection pphc05169   Epstein-Barr virus infection pphc05171   Coronavirus disease - COVID-19 pphc05200   Pathways in cancer pphc05203   Viral carcinogenesis pphc05212   Pancreatic cancer pphc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pphc00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     136123211 (JAK1)    04151 PI3K-Akt signaling pathway     136123211 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     136123211 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     136123211 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     136123211 (JAK1)    04621 NOD-like receptor signaling pathway     136123211 (JAK1)    04658 Th1 and Th2 cell differentiation     136123211 (JAK1)    04659 Th17 cell differentiation     136123211 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     136123211 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     136123211 (JAK1)    05203 Viral carcinogenesis     136123211 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     136123211 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     136123211 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     136123211 (JAK1)    05161 Hepatitis B     136123211 (JAK1)    05160 Hepatitis C     136123211 (JAK1)    05171 Coronavirus disease - COVID-19     136123211 (JAK1)    05164 Influenza A     136123211 (JAK1)    05162 Measles     136123211 (JAK1)    05168 Herpes simplex virus 1 infection     136123211 (JAK1)    05163 Human cytomegalovirus infection     136123211 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     136123211 (JAK1)    05169 Epstein-Barr virus infection     136123211 (JAK1)    05165 Human papillomavirus infection     136123211 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     136123211 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     136123211 (JAK1)    05140 Leishmaniasis     136123211 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     136123211 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pphc01001]     136123211 (JAK1) Enzymes [BR:pphc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      136123211 (JAK1) Protein kinases [BR:pphc01001]  Non-receptor tyrosine kinases   JAK family [OT]    136123211 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 SH2_1 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  136123211 NCBI-ProteinID:  XP_065733325 LinkDB All DBs Position 1:complement(55777607..55916282) Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTDVNLEAPEPGVEVLFYLSDREPLRLGGGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNSYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN RFHPNDNGNILCYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSELLGVQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGTDSECGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPEEVYQLMRKCWEFQPSIRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatttaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgacgtgaatctggaggcccctgagccaggggtggaagtgctcttc tatctgtcggacagggagcccctccggttgggcggcggagagtacacagcggaggagctg tgcatcagggcggcgcaggaatgctgtatatctcctctgtgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccgtcgacgacaag atgtcactccggctccactaccggatgaggttctatttcaccaactggcacgggaccaat gataacgagcagtcagtatggcgacattctccaaagaagcagaagaatagctacgagaaa aaaaaagttccagatgcaacccctctccttgacgccagctcattggagtatctgtttgct cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagacggagcag gatgggcatgatattgagaacgagtgtctgggaatggccgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggagtttaacaacaagaccatttgtgacagcagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgctactgatttcatcagaaaatgagatgaat cggttccatccgaatgataatggaaacattctctgctatgaagtgatggtgactggaaat cttggaatccagtggaggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaataaaatccgg gaagagtggaacaatttttcttacttccctgagatcactcacattgtaatcaaggagtct gtggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgag gaggccttgtcctttgtgtccctcgtggacggctacttccggctcacagcagatgcccat cattacctctgcaccgacgtggctcccccgttgatcgtccacaacatacagaatggctgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggag ggaatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcact tgctttgaaaagtctgagttgctgggtgtccagaagcagttcaagaactttcagattgag gtgcagaagggccgctacagcctgcatggctcagaccgaagcttccccagccttggagac ctcatgagccacctgaagaagcagatcctgcgcacggacaacatcagctttgtgctgaag cgctgctgccagcccaagccccgagaaatctccaatctgctggtggccaccaagaaagcc caggagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatattatgcagggcgagcaccttgggagaggcacgcgaacacacatctactctgggacc ctcatggattacaaggatgatgaaggaacttccgaagagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttctctggccttctttgaggcagccagcatg atgagacaggtctcccataaacacatcgtgtacctctatggcgtttgtgtccgagacgtg gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg aaaagtgatgtcctcaccacaccctggaagttcaaagttgccaaacagctggccagcgcc ctgagttacttggaggataaagatctggtccacggaaatgtgtgcactaaaaacctcctc ctggcccgcgagggcactgacagcgagtgcggccccttcatcaagctcagtgaccccggc atccccgtcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctcct gagtgtgttgaagactccaagaacctgagtgtggccgctgacaagtggagctttggaacc acgctctgggagatctgctacaatggcgagatccccttgaaagacaagacactgattgag aaagagaggttctatgaaagccggtgcaggccagtgaccccgtcttgtaaggagctagct gaccttatgacccgctgcatgaactacgaccccaaccagagacccttcttccgagccatc atgagagacatcaataagctggaggagcagaatccagacatcgtatcagaaaaaaagcca gcaactgaagtggatcccacacattttgaaaagcggttcttaaagaggatccgtgacttg ggagagggccactttgggaaggtcgagctctgcaggtatgaccctgagggggacaataca ggggagcaggtggccgtcaaatccctgaagcccgagagcggagggaaccacatagctgat ctgaagaaggaaattgaaatcttaagaaacctttatcatgagaacattgtgaagtataaa ggcatctgcacagaagacggaggaaacggtattaagctcatcatggaatttctgccttca ggaagtcttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcagtta aaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatacgttcac cgtgacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggggac tttggtctaaccaaagccattgaaactgataaggagtactacacagtcaaggacgatcgg gacagccctgtgttttggtatgctccagaatgtttaattcagtgtaagttttatatcgcc tctgatgtctggtcttttggagtaactctgcatgagctgcttacttactgtgattcagat tccagtcccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctaactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccaaccatccattcggacaacc tttcagaaccttattgagggatttgaagcgcttctaaaataa

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