KEGG   Phocoena phocoena (harbor porpoise): 136123619
Entry
136123619         CDS       T11058                                 
Symbol
PPP3CA
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc04010  MAPK signaling pathway
pphc04020  Calcium signaling pathway
pphc04022  cGMP-PKG signaling pathway
pphc04114  Oocyte meiosis
pphc04218  Cellular senescence
pphc04310  Wnt signaling pathway
pphc04360  Axon guidance
pphc04370  VEGF signaling pathway
pphc04380  Osteoclast differentiation
pphc04625  C-type lectin receptor signaling pathway
pphc04650  Natural killer cell mediated cytotoxicity
pphc04658  Th1 and Th2 cell differentiation
pphc04659  Th17 cell differentiation
pphc04660  T cell receptor signaling pathway
pphc04662  B cell receptor signaling pathway
pphc04720  Long-term potentiation
pphc04724  Glutamatergic synapse
pphc04728  Dopaminergic synapse
pphc04921  Oxytocin signaling pathway
pphc04922  Glucagon signaling pathway
pphc04924  Renin secretion
pphc05010  Alzheimer disease
pphc05014  Amyotrophic lateral sclerosis
pphc05020  Prion disease
pphc05022  Pathways of neurodegeneration - multiple diseases
pphc05031  Amphetamine addiction
pphc05152  Tuberculosis
pphc05163  Human cytomegalovirus infection
pphc05166  Human T-cell leukemia virus 1 infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05170  Human immunodeficiency virus 1 infection
pphc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pphc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136123619 (PPP3CA)
   04310 Wnt signaling pathway
    136123619 (PPP3CA)
   04370 VEGF signaling pathway
    136123619 (PPP3CA)
   04020 Calcium signaling pathway
    136123619 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    136123619 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    136123619 (PPP3CA)
   04218 Cellular senescence
    136123619 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    136123619 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    136123619 (PPP3CA)
   04660 T cell receptor signaling pathway
    136123619 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    136123619 (PPP3CA)
   04659 Th17 cell differentiation
    136123619 (PPP3CA)
   04662 B cell receptor signaling pathway
    136123619 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    136123619 (PPP3CA)
   04921 Oxytocin signaling pathway
    136123619 (PPP3CA)
   04924 Renin secretion
    136123619 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    136123619 (PPP3CA)
   04728 Dopaminergic synapse
    136123619 (PPP3CA)
   04720 Long-term potentiation
    136123619 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    136123619 (PPP3CA)
   04380 Osteoclast differentiation
    136123619 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136123619 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136123619 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    136123619 (PPP3CA)
   05163 Human cytomegalovirus infection
    136123619 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136123619 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    136123619 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136123619 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    136123619 (PPP3CA)
   05020 Prion disease
    136123619 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    136123619 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    136123619 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136123619 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pphc01009]
    136123619 (PPP3CA)
Enzymes [BR:pphc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     136123619 (PPP3CA)
Protein phosphatases and associated proteins [BR:pphc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     136123619 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 136123619
NCBI-ProteinID: XP_065734016
LinkDB
Position
5:complement(18569511..18868397)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDTNLNSINKTLASETNGTDSNGSNNSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccgtttcctccaagtcaccggcttacggcaaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataatcacagagggggcttcaattcttcgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgcggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggcggatctcctgccaacactcgctacctcttcttaggggactatgta
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctatgtgtacacggc
ggtttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacccgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcgcaagacgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgttttcacttggtccctgccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagag
gaagatggatttgatggtgcaacggctgcagcccgcaaggaagtgatacggaacaagatc
cgagcaatcggcaagatggccagagtgttctccgtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacgcccacgggcatgctccccagtggagtgctctctggaggg
aagcaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagatcgaattaac
gagaggatgccacctcgcagagatgccatgccctctgacaccaaccttaactccatcaac
aagactctcgcatcagagactaacggcacggacagcaatggcagtaataacagcaatatc
cagtga

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