Phocoena phocoena (harbor porpoise): 136124967
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Entry
136124967 CDS
T11058
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04015
Rap1 signaling pathway
pphc04024
cAMP signaling pathway
pphc04062
Chemokine signaling pathway
pphc04510
Focal adhesion
pphc04517
IgSF CAM signaling
pphc04650
Natural killer cell mediated cytotoxicity
pphc04660
T cell receptor signaling pathway
pphc04662
B cell receptor signaling pathway
pphc04664
Fc epsilon RI signaling pathway
pphc04666
Fc gamma R-mediated phagocytosis
pphc04670
Leukocyte transendothelial migration
pphc04810
Regulation of actin cytoskeleton
pphc05135
Yersinia infection
pphc05205
Proteoglycans in cancer
pphc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
136124967 (VAV2)
04024 cAMP signaling pathway
136124967 (VAV2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
136124967 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
136124967 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
136124967 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
136124967 (VAV2)
04660 T cell receptor signaling pathway
136124967 (VAV2)
04662 B cell receptor signaling pathway
136124967 (VAV2)
04664 Fc epsilon RI signaling pathway
136124967 (VAV2)
04666 Fc gamma R-mediated phagocytosis
136124967 (VAV2)
04670 Leukocyte transendothelial migration
136124967 (VAV2)
04062 Chemokine signaling pathway
136124967 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
136124967 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
136124967 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
136124967 (VAV2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
C1_1
PH
DUF7145
SH2_2
RHG20_PH
C1_2
CDC24
PLU-1
PH_10
DH_Alsin
ANC1_spectrin
Motif
Other DBs
NCBI-GeneID:
136124967
NCBI-ProteinID:
XP_065735892
LinkDB
All DBs
Position
6:113083399..113259722
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AA seq
878 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDV
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHNL
AQTKGIRPFPSEETTENDDDVYRSLEELADEHDVGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMIRYMQKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYVTPLRLVLSPADMAAI
FINLEDLIKVHHSFLRAIDVSMMAGGSTLAKVFLDFKERLLIYGEYCSRMEHAQNTLSQL
LASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLK
EALEAMQDLAMYINEVKRDKETLKKIGEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNH
TKQDRYLFLFDKAVIVCKRRGDSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFY
LIHLQGKQGFQFFCKTEDMKRKWTEQFEMAMSNIKPDKATANQHSFQMYTFDRTTNCRAC
GMFLRGTFYQGYLCTKCGVGAHKECLEVTPPCKISSPADLDTSGAGPGPKMVAMQNYHGN
PAPPGKPVLTFQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISR
PPSRDMDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHI
KVVEKDSWVHITEAKKFESLSELVEYYQCHSLKESFKQLDTTLKYPYKSRERVASRASSR
SPASCASYNFSFLSPQGFSLASQGSSVPFWPVFTPRVIGTAVARYNFAARDLRELSLREG
DVVKIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
NT seq
2637 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggccgtggtcttcgacctggcccaggcgctgcgcgacggc
gtcctcctgtgccagctgctgcacaacctctcccccggctccatcgacctcaaggacgtc
aacttccggccgcagatgtcccagttcctgtgtttgaagaacattcgcaccttccttaaa
gtctgccacgacaaatttggactcaggaacagcgagctgtttgaccccttcgacctcttc
gatgtccgagactttgggaaggtcatctcggctgtgtcgaggctctccctgcacaacttg
gctcagaccaaagggatcaggcccttcccctcggaggagaccacggagaatgatgatgac
gtctaccgcagcctggaggaactggcagatgagcatgacgtgggggaggacatctacgac
tgtgtcccgtgcgaagatgaaggggacgacatttatgaggacatcatcaaggtggaagtg
cagcagcccatgattagatacatgcagaaaatgggcatgacggaggacgacaagagaagc
tgctgtctgctggagatccaggagacggaagccaagtactaccggaccctggaggacatc
gagaagaactacgtgacccctctcaggctggtgctgagcccggcggacatggcggccatc
ttcatcaacctggaggacctaattaaggtgcatcacagcttcctgagagccatcgacgtg
tccatgatggcggggggcagcacgctggccaaggtcttcctggacttcaaggaaaggctc
ctgatctacggggagtactgcagccgcatggagcacgcccagaacacgctgagccagctc
ctggccagcagggaggacttcagacagaaagtcgaggaatgcaccctgaaggtccaagac
gggaagtttaagctgcaggacctgctggtggtccccatgcagagggtgctcaaataccac
ctgctcctcaaggaacttctgagccattccaccgaccggcccgagaggcagcagctcaaa
gaagcgctggaggccatgcaggacctggcgatgtacatcaacgaagtcaaacgggacaaa
gagaccctgaagaaaatcggcgagtttcagagttccatagagaacctgcaagtgaaactg
gaggaatttgggagaccaaaaatcgatggggagctgaaggtccggtccatagtgaatcac
accaagcaagacaggtacctgttcctgtttgacaaggcggtcattgtgtgcaagaggagg
ggcgacagctacgagctgaaggagatcattgagctgcttttccacaagatgaccgacgac
cccatgaacaacaaggacgtcaagaagtctcacgggaaaatgtggtcctacggtttctat
ctaattcaccttcaaggcaagcaaggcttccagtttttctgcaagacggaagacatgaag
aggaagtggacggaacagtttgagatggccatgtcaaacatcaagcccgacaaagccacc
gccaaccagcacagcttccagatgtacacgtttgacaggaccaccaactgcagagcatgc
gggatgttcctcagaggcaccttctaccagggttacctgtgcaccaagtgtggcgtcggg
gcacacaaggagtgcctggaggtgacccctccctgcaagatcagttctcctgcagacctg
gacacctctggagcggggccaggtcccaagatggtggccatgcagaattaccatggcaac
cctgctccccccgggaagccggtgctgaccttccagacgggtgatgtgattgagctactg
agaggcgaccctgagtctcagtggtgggagggtcggttggtgcaaaccaggaagtcaggt
tacttccctagctcgtctgtgaagccctgtccagtggatggaaggccgcccatcagccgg
ccgccgtcccgggatatggactacaccgcatacccctggtttgccggcaacatggaacgg
cagcagaccgacaacctgctcaaatcccacgccagcgggacctacctaatcagggagcgg
ccggccgaggccgagcgctttgccataagcatcaaattcaatgacgaggtgaaacacatc
aaggtggtggagaaggacagctgggtgcacatcaccgaagccaagaaatttgaaagcctc
tcagagttggtagagtactaccagtgccactcgctcaaggagagcttcaagcagttggac
accacgctcaagtacccctacaagtcacgggaacgcgtggcctctagggcctccagccgg
tccccagcttcctgcgcttcctacaacttttcttttctcagtcctcagggcttcagcctt
gcttctcagggctcctccgtgcccttctggccagtgtttacgccccgcgtcatcggcacg
gccgtggccaggtacaacttcgctgcccgggacctgcgggagctctcgctgcgagaaggc
gacgtggtgaagatctacagccgcatcggtggggaccagggctggtggaagggcgagacc
aacggccggatcggctggtttccttcaacgtacgtagaagaagagggcatccagtga
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