Phocoena phocoena (harbor porpoise): 136128127
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Entry
136128127 CDS
T11058
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X1
KO
K12407
glucokinase [EC:
2.7.1.2
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00010
Glycolysis / Gluconeogenesis
pphc00052
Galactose metabolism
pphc00500
Starch and sucrose metabolism
pphc00520
Amino sugar and nucleotide sugar metabolism
pphc00524
Neomycin, kanamycin and gentamicin biosynthesis
pphc01100
Metabolic pathways
pphc01200
Carbon metabolism
pphc01250
Biosynthesis of nucleotide sugars
pphc04910
Insulin signaling pathway
pphc04911
Insulin secretion
pphc04917
Prolactin signaling pathway
pphc04922
Glucagon signaling pathway
pphc04930
Type II diabetes mellitus
pphc04950
Maturity onset diabetes of the young
pphc05230
Central carbon metabolism in cancer
Module
pphc_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
pphc_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
136128127 (GCK)
00052 Galactose metabolism
136128127 (GCK)
00500 Starch and sucrose metabolism
136128127 (GCK)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
136128127 (GCK)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
136128127 (GCK)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
136128127 (GCK)
04910 Insulin signaling pathway
136128127 (GCK)
04922 Glucagon signaling pathway
136128127 (GCK)
04917 Prolactin signaling pathway
136128127 (GCK)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
136128127 (GCK)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
136128127 (GCK)
04950 Maturity onset diabetes of the young
136128127 (GCK)
Enzymes [BR:
pphc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
136128127 (GCK)
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Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
136128127
NCBI-ProteinID:
XP_065739919
LinkDB
All DBs
Position
9:9671867..9720252
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AA seq
466 aa
AA seq
DB search
MAMEATRSWVQTALNLVEQILAEFQLQDEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVCSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLFEKLIGGKYMG
ELVRLVLLKLVDENLLFHGEASEKLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRP
SATDCDIVRRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggcgatggaggccacaaggagctgggtccagacagctttgaatctggtggaacagatc
ctggcggagttccagctgcaggatgaggacttgaagaaggtgatgaggcggatgcagaag
gagatggaccgaggcctgaggctggagacacacgaggaggccagtgtgaagatgctgccc
acctacgtgtgctctaccccggaaggctcagaagtcggggatttcctctccctggacctg
ggcggcaccaacttcagggtgatgcttgtgaaggtgggggaaggggaggagggacagtgg
agtgtgaaaaccaagcaccagatgtactccatccccgaggacgccatgacgggcactgct
gagatgctctttgactacatctctgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccttgggcttcaccttctcctttcctgtgagacacgaagacatc
gacaagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac
aacatcgtggggctcctgcgagatgccatcaaacggagaggggactttgagatggacgtg
gtggcgatggtgaacgacactgtggccacgatgatctcctgctactatgaagaccgccgg
tgtgaggttggcatgattgtgggcacgggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggtgcc
ttcggggactcgggcgagctggacgagttcctgctggagtacgaccgtgtggtggacgag
aactccctgaaccccggccagcagctgttcgagaagctcatcggcggcaagtacatgggc
gagctggtgcggctcgtgctgctgaagcttgtggacgagaacctactcttccacggggag
gcctcggagaagctgcgcacgcgcggcgccttcgagacacgcttcgtgtcgcaggtggag
agtgactcgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgaggccg
tcggccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacccgcgccgcg
cgcatgtgcgccgcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacgtgatgcgcatcaccgtgggcgtggacggctcagtgtacaagctgcaccccagcttc
aaggagcggttccacgccagcgtgcgcaggctgacgcccagctgtgaaatcaccttcatc
gagtcggaggagggcagcggccggggtgcggccttgatctccgcggtggcctgtaagaag
gcctgcatgctgggccagtga
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