KEGG   Phocoena phocoena (harbor porpoise): 136128127
Entry
136128127         CDS       T11058                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc00010  Glycolysis / Gluconeogenesis
pphc00052  Galactose metabolism
pphc00500  Starch and sucrose metabolism
pphc00520  Amino sugar and nucleotide sugar metabolism
pphc00524  Neomycin, kanamycin and gentamicin biosynthesis
pphc01100  Metabolic pathways
pphc01200  Carbon metabolism
pphc01250  Biosynthesis of nucleotide sugars
pphc04910  Insulin signaling pathway
pphc04911  Insulin secretion
pphc04917  Prolactin signaling pathway
pphc04922  Glucagon signaling pathway
pphc04930  Type II diabetes mellitus
pphc04950  Maturity onset diabetes of the young
pphc05230  Central carbon metabolism in cancer
Module
pphc_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
pphc_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    136128127 (GCK)
   00052 Galactose metabolism
    136128127 (GCK)
   00500 Starch and sucrose metabolism
    136128127 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    136128127 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    136128127 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    136128127 (GCK)
   04910 Insulin signaling pathway
    136128127 (GCK)
   04922 Glucagon signaling pathway
    136128127 (GCK)
   04917 Prolactin signaling pathway
    136128127 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    136128127 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    136128127 (GCK)
   04950 Maturity onset diabetes of the young
    136128127 (GCK)
Enzymes [BR:pphc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     136128127 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 136128127
NCBI-ProteinID: XP_065739919
LinkDB
Position
9:9671867..9720252
AA seq 466 aa
MAMEATRSWVQTALNLVEQILAEFQLQDEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVCSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQLFEKLIGGKYMG
ELVRLVLLKLVDENLLFHGEASEKLRTRGAFETRFVSQVESDSGDRKQIYNILSTLGLRP
SATDCDIVRRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggcgatggaggccacaaggagctgggtccagacagctttgaatctggtggaacagatc
ctggcggagttccagctgcaggatgaggacttgaagaaggtgatgaggcggatgcagaag
gagatggaccgaggcctgaggctggagacacacgaggaggccagtgtgaagatgctgccc
acctacgtgtgctctaccccggaaggctcagaagtcggggatttcctctccctggacctg
ggcggcaccaacttcagggtgatgcttgtgaaggtgggggaaggggaggagggacagtgg
agtgtgaaaaccaagcaccagatgtactccatccccgaggacgccatgacgggcactgct
gagatgctctttgactacatctctgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccttgggcttcaccttctcctttcctgtgagacacgaagacatc
gacaagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac
aacatcgtggggctcctgcgagatgccatcaaacggagaggggactttgagatggacgtg
gtggcgatggtgaacgacactgtggccacgatgatctcctgctactatgaagaccgccgg
tgtgaggttggcatgattgtgggcacgggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggacgagggccgcatgtgtgtcaacaccgagtggggtgcc
ttcggggactcgggcgagctggacgagttcctgctggagtacgaccgtgtggtggacgag
aactccctgaaccccggccagcagctgttcgagaagctcatcggcggcaagtacatgggc
gagctggtgcggctcgtgctgctgaagcttgtggacgagaacctactcttccacggggag
gcctcggagaagctgcgcacgcgcggcgccttcgagacacgcttcgtgtcgcaggtggag
agtgactcgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgaggccg
tcggccaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacccgcgccgcg
cgcatgtgcgccgcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacgtgatgcgcatcaccgtgggcgtggacggctcagtgtacaagctgcaccccagcttc
aaggagcggttccacgccagcgtgcgcaggctgacgcccagctgtgaaatcaccttcatc
gagtcggaggagggcagcggccggggtgcggccttgatctccgcggtggcctgtaagaag
gcctgcatgctgggccagtga

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