Phocoena phocoena (harbor porpoise): 136129718
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Entry
136129718 CDS
T11058
Symbol
MLH1
Name
(RefSeq) DNA mismatch repair protein Mlh1 isoform X1
KO
K08734
DNA mismatch repair protein MLH1
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc01524
Platinum drug resistance
pphc03430
Mismatch repair
pphc03460
Fanconi anemia pathway
pphc05200
Pathways in cancer
pphc05210
Colorectal cancer
pphc05213
Endometrial cancer
pphc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09120 Genetic Information Processing
09124 Replication and repair
03430 Mismatch repair
136129718 (MLH1)
03460 Fanconi anemia pathway
136129718 (MLH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
136129718 (MLH1)
09162 Cancer: specific types
05210 Colorectal cancer
136129718 (MLH1)
05226 Gastric cancer
136129718 (MLH1)
05213 Endometrial cancer
136129718 (MLH1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
136129718 (MLH1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
pphc03400
]
136129718 (MLH1)
DNA repair and recombination proteins [BR:
pphc03400
]
Eukaryotic type
SSBR (single strand breaks repair)
MMR (mismatch excision repair)
MutL homologs
136129718 (MLH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mlh1_C
DNA_mis_repair
HATPase_c_3
HATPase_c
DUF4921
Hfx_Cass5
Motif
Other DBs
NCBI-GeneID:
136129718
NCBI-ProteinID:
XP_065742097
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All DBs
Position
10:49243160..49294347
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AA seq
759 aa
AA seq
DB search
MSLVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVVIKEGGLKLIQ
IQDNGTGIRKEDLEIVCERFTTSKLQSFEDLAHISTYGFRGEALASISHVAHVSITTKTA
DGKCAYRAHYSDGKLKAPPKPCAGNQGTQITVEDLFYNISTRRKALKNPSEEYGKILEVV
GRYSVHNSGISFSVKKQGETVADVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF
KMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISP
QNVDVNVHPTKHEVHFLHEDSILERVQQHIESRLLGSNASRTYFTQTLLPGLTGPSGEVV
KSTTGVTLSSTAGSGDKVYAHQMVRTDCREQKLDAFVQPVSKALSSQPQAVVLEDRTAAS
SSGARQQDEEMLELSAPAEVAAKNQGLEEDAAKRTADLSEKRGPSSSPENPRKRHREGSD
LEMVEDASQKEMTAACTPRRRIINLTSILSLQEEISERGHETLREVLRNHSFVGCVNPQW
ALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWT
EEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEQEGNLVGLPLLIDNYVPPLEGLPIFI
LRLATEVNWDDEKECFESLGKECAMFYSIRKQYVSEESTLSGQQSEVPSSTPNPWKWTVE
HVVYKAFRSHLLPPKHFTEDGNILQLANLPDLYKVFERC
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctggtagcgggggttatccggcggctggacgagacagtggtgaaccgcatcgcg
gcaggggaagttatccagcgcccggctaatgctatcaaggagatgatagaaaactgttta
gatgcaaaatccacaagtattcaagtggttattaaagagggaggcctgaagttgattcag
atccaagacaatggcaccgggatcaggaaagaagatctggagattgtgtgtgagaggttc
accacaagtaaactgcagtcctttgaggatttagctcatatttctacctatggctttcgg
ggcgaggctttggccagcataagccatgtggctcacgtcagcattacaaccaaaacagct
gacgggaagtgtgcatacagagcacattactcagatggaaagctgaaagctccacctaaa
ccatgtgcaggcaatcaagggacccagatcacggtagaggaccttttctacaacatatcc
acgaggaggaaagctttaaaaaatccaagtgaagagtatgggaaaattctggaagttgtc
ggcaggtattcagtacacaattcaggcattagtttctcggttaaaaaacaaggtgagacg
gtagccgacgtcaggacactgcccaatgccacaaccgtggacaacattcgctccattttt
ggaaatgctgttagccgagaattgatagaagttgggtgtgaggataaaaccctcgccttc
aaaatgaatggctacatatccaatgcaaactactcggtgaagaagtgcatcttcttactc
ttcatcaatcatcgtctggtagagtcaacttccttaagaaaagccatagaaacggtgtat
gcagcatatttgcccaaaaacacacacccgttcctgtacctcagtttagaaatcagcccc
cagaatgtggatgtcaacgtgcaccccacgaagcacgaagttcacttcctgcacgaggac
agcatcctggagcgggtgcagcagcacattgagagcaggctcctgggctccaacgcctcc
aggacctatttcacccagactttactaccaggtcttactggcccctctggggaagtggtt
aaatccacaacaggtgtgactctctcatctactgctggaagtggcgacaaggtgtatgcc
caccagatggtccgcacagattgccgggaacagaaactcgatgccttcgtgcagcctgtg
agcaaggccctatccagtcagccccaggctgttgtcctagaggacaggacagctgcttct
agtagcggggccaggcagcaggatgaggaaatgcttgaactctcagctcctgctgaagtg
gctgccaagaatcagggcttggaggaggatgcagcaaagaggactgcagacttgtcagag
aagagagggccctcttccagccctgagaaccccagaaaaagacatcgggaaggctctgat
ttggaaatggtggaggatgcatcccaaaaggaaatgacagcagcttgtaccccccggaga
aggatcattaaccttaccagcattctgagtctccaggaagaaatcagtgagcggggacat
gagactctccgggaggtgctgcgtaaccactcatttgtgggctgtgtgaatccgcaatgg
gccttggcacagcatcagaccaagttataccttctcaacaccaccaaacttagtgaagaa
ctgttctatcagattctcatttatgattttgccaattttggtgttctgaggttatcggag
ccagcaccactctttgacctcgccatgcttgccttagatagtcctgagagtggctggaca
gaggaagatggtcccaaagaaggacttgctgaatacattgttgagtttctgaaaaagaag
gctgagatgcttgcagactacttctctttggagattgatgagcaggaagggaacctggtt
ggattaccccttctgatcgacaactacgtgccccccttggagggtctgcctatcttcatt
ctccgactggccactgaggtgaactgggatgacgaaaaggaatgttttgaaagccttggt
aaagaatgtgcgatgttttactccatccggaagcagtatgtgtctgaggagtcgaccctc
tcaggccagcagagtgaagtgcccagctctactccaaacccctggaagtggactgtggag
catgttgtctataaagccttccgctcacaccttctgcctccgaaacatttcacagaagat
ggaaacatcctgcagcttgctaacctgcccgatctatataaagtcttcgagaggtgttaa
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