KEGG   Phocoena phocoena (harbor porpoise): 136129974
Entry
136129974         CDS       T11058                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc01522  Endocrine resistance
pphc04010  MAPK signaling pathway
pphc04015  Rap1 signaling pathway
pphc04068  FoxO signaling pathway
pphc04071  Sphingolipid signaling pathway
pphc04114  Oocyte meiosis
pphc04148  Efferocytosis
pphc04218  Cellular senescence
pphc04261  Adrenergic signaling in cardiomyocytes
pphc04370  VEGF signaling pathway
pphc04380  Osteoclast differentiation
pphc04550  Signaling pathways regulating pluripotency of stem cells
pphc04611  Platelet activation
pphc04613  Neutrophil extracellular trap formation
pphc04620  Toll-like receptor signaling pathway
pphc04621  NOD-like receptor signaling pathway
pphc04622  RIG-I-like receptor signaling pathway
pphc04625  C-type lectin receptor signaling pathway
pphc04657  IL-17 signaling pathway
pphc04658  Th1 and Th2 cell differentiation
pphc04659  Th17 cell differentiation
pphc04660  T cell receptor signaling pathway
pphc04664  Fc epsilon RI signaling pathway
pphc04668  TNF signaling pathway
pphc04670  Leukocyte transendothelial migration
pphc04714  Thermogenesis
pphc04722  Neurotrophin signaling pathway
pphc04723  Retrograde endocannabinoid signaling
pphc04728  Dopaminergic synapse
pphc04750  Inflammatory mediator regulation of TRP channels
pphc04912  GnRH signaling pathway
pphc04914  Progesterone-mediated oocyte maturation
pphc04917  Prolactin signaling pathway
pphc04926  Relaxin signaling pathway
pphc04932  Non-alcoholic fatty liver disease
pphc04933  AGE-RAGE signaling pathway in diabetic complications
pphc04935  Growth hormone synthesis, secretion and action
pphc04936  Alcoholic liver disease
pphc05014  Amyotrophic lateral sclerosis
pphc05020  Prion disease
pphc05022  Pathways of neurodegeneration - multiple diseases
pphc05132  Salmonella infection
pphc05133  Pertussis
pphc05135  Yersinia infection
pphc05140  Leishmaniasis
pphc05142  Chagas disease
pphc05145  Toxoplasmosis
pphc05152  Tuberculosis
pphc05161  Hepatitis B
pphc05163  Human cytomegalovirus infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05169  Epstein-Barr virus infection
pphc05170  Human immunodeficiency virus 1 infection
pphc05171  Coronavirus disease - COVID-19
pphc05205  Proteoglycans in cancer
pphc05208  Chemical carcinogenesis - reactive oxygen species
pphc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pphc05415  Diabetic cardiomyopathy
pphc05417  Lipid and atherosclerosis
pphc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136129974 (MAPK13)
   04015 Rap1 signaling pathway
    136129974 (MAPK13)
   04370 VEGF signaling pathway
    136129974 (MAPK13)
   04668 TNF signaling pathway
    136129974 (MAPK13)
   04068 FoxO signaling pathway
    136129974 (MAPK13)
   04071 Sphingolipid signaling pathway
    136129974 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    136129974 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    136129974 (MAPK13)
   04218 Cellular senescence
    136129974 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    136129974 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136129974 (MAPK13)
   04613 Neutrophil extracellular trap formation
    136129974 (MAPK13)
   04620 Toll-like receptor signaling pathway
    136129974 (MAPK13)
   04621 NOD-like receptor signaling pathway
    136129974 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    136129974 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    136129974 (MAPK13)
   04660 T cell receptor signaling pathway
    136129974 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    136129974 (MAPK13)
   04659 Th17 cell differentiation
    136129974 (MAPK13)
   04657 IL-17 signaling pathway
    136129974 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    136129974 (MAPK13)
   04670 Leukocyte transendothelial migration
    136129974 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    136129974 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    136129974 (MAPK13)
   04917 Prolactin signaling pathway
    136129974 (MAPK13)
   04926 Relaxin signaling pathway
    136129974 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    136129974 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    136129974 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    136129974 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    136129974 (MAPK13)
   04722 Neurotrophin signaling pathway
    136129974 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136129974 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136129974 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    136129974 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    136129974 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    136129974 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136129974 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136129974 (MAPK13)
   05161 Hepatitis B
    136129974 (MAPK13)
   05171 Coronavirus disease - COVID-19
    136129974 (MAPK13)
   05163 Human cytomegalovirus infection
    136129974 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136129974 (MAPK13)
   05169 Epstein-Barr virus infection
    136129974 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136129974 (MAPK13)
   05135 Yersinia infection
    136129974 (MAPK13)
   05133 Pertussis
    136129974 (MAPK13)
   05152 Tuberculosis
    136129974 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136129974 (MAPK13)
   05140 Leishmaniasis
    136129974 (MAPK13)
   05142 Chagas disease
    136129974 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    136129974 (MAPK13)
   05020 Prion disease
    136129974 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    136129974 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136129974 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    136129974 (MAPK13)
   05415 Diabetic cardiomyopathy
    136129974 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136129974 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    136129974 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136129974 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    136129974 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pphc01001]
    136129974 (MAPK13)
Enzymes [BR:pphc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     136129974 (MAPK13)
Protein kinases [BR:pphc01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   136129974 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kinase-like
Other DBs
NCBI-GeneID: 136129974
NCBI-ProteinID: XP_065742422
LinkDB
Position
10:66937154..66945959
AA seq 366 aa
MNFTWKKGFYKQDVNMTAWELPKTYVSLTHVGSGAYGAVCSAIEKQSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHKNVIGLLDVFTPASSLRNFHDFYLVMPFMQMDLQKIMGM
EFGEDKIQYLVYQMLKGLKYIHSAGVIHRDLKPGNLAVNEDCELKILDFGLARQADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPDAEFVQKLNDKAAKSYIQSLPQIPKKDFSQLFPHASPQAADLLEKMLELDMDKRLTAS
QALTHPFFESCRDPEEETEAQQPFDDFLEQEKLTVDEWKQHIYKEIVNFRPIARKDSRRR
SGMKLQ
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgaacttcacctggaaaaagggcttctacaagcaggacgtcaacatgaccgcctgggag
ctgcccaagacctacgtgtccctgacgcacgtaggcagcggggcctacggcgccgtgtgc
tcagccatcgagaagcagtcaggggagaaggtggccatcaagaagctgagccggcccttc
cagtctgagatctttgccaagcgggcctatcgtgagctgctgctgctgaagcacatgcag
cacaagaacgtcatcggactcctggatgtcttcaccccagcctcttccctgcgcaacttt
catgatttctacctggtgatgcccttcatgcagatggacctgcagaagatcatgggaatg
gagttcggtgaggacaagatccagtacctggtgtatcagatgctcaaaggtcttaagtac
atccactcagctggggtcatccacagggacctgaagccaggcaaccttgctgtcaatgag
gattgtgagctgaagattttggattttgggttggcacggcaagcagatgcagagatgact
ggctatgtggtgacccgctggtaccgggcccccgaggtgatcctcagctggatgcattac
aaccagactgtggacatctggtctgtgggctgtatcatggcagagatgctgacggggaaa
actctgttcaaggggaaagattacctggaccagctgacgcagatcctgaaagtgacgggg
gtgccggacgctgagtttgtgcagaagttgaatgacaaagcggccaaatcctacatccag
tccctgccacaaatccccaagaaggatttctctcagctcttcccgcatgccagcccccag
gctgcagacctgctggagaagatgctggagctggacatggacaagcgcctgaccgcctct
caggccctcacccaccccttctttgaatcctgccgggaccctgaggaggaaacagaggcc
cagcagccatttgatgatttcttagaacaggagaaactcacagtggatgaatggaagcag
cacatttacaaggagattgtgaacttccgccccatcgcccggaaggactctcggcgccgg
agtggcatgaagctgcagtga

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