KEGG   Phocoena phocoena (harbor porpoise): 136130428
Entry
136130428         CDS       T11058                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc01521  EGFR tyrosine kinase inhibitor resistance
pphc01522  Endocrine resistance
pphc04010  MAPK signaling pathway
pphc04014  Ras signaling pathway
pphc04015  Rap1 signaling pathway
pphc04066  HIF-1 signaling pathway
pphc04068  FoxO signaling pathway
pphc04081  Hormone signaling
pphc04114  Oocyte meiosis
pphc04115  p53 signaling pathway
pphc04150  mTOR signaling pathway
pphc04151  PI3K-Akt signaling pathway
pphc04152  AMPK signaling pathway
pphc04211  Longevity regulating pathway
pphc04213  Longevity regulating pathway - multiple species
pphc04510  Focal adhesion
pphc04550  Signaling pathways regulating pluripotency of stem cells
pphc04730  Long-term depression
pphc04750  Inflammatory mediator regulation of TRP channels
pphc04913  Ovarian steroidogenesis
pphc04914  Progesterone-mediated oocyte maturation
pphc04935  Growth hormone synthesis, secretion and action
pphc04960  Aldosterone-regulated sodium reabsorption
pphc05200  Pathways in cancer
pphc05202  Transcriptional misregulation in cancer
pphc05205  Proteoglycans in cancer
pphc05214  Glioma
pphc05215  Prostate cancer
pphc05218  Melanoma
pphc05224  Breast cancer
pphc05410  Hypertrophic cardiomyopathy
pphc05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136130428 (IGF1)
   04014 Ras signaling pathway
    136130428 (IGF1)
   04015 Rap1 signaling pathway
    136130428 (IGF1)
   04066 HIF-1 signaling pathway
    136130428 (IGF1)
   04068 FoxO signaling pathway
    136130428 (IGF1)
   04151 PI3K-Akt signaling pathway
    136130428 (IGF1)
   04152 AMPK signaling pathway
    136130428 (IGF1)
   04150 mTOR signaling pathway
    136130428 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    136130428 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    136130428 (IGF1)
   04115 p53 signaling pathway
    136130428 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136130428 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    136130428 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    136130428 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    136130428 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    136130428 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    136130428 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    136130428 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136130428 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    136130428 (IGF1)
   04213 Longevity regulating pathway - multiple species
    136130428 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136130428 (IGF1)
   05202 Transcriptional misregulation in cancer
    136130428 (IGF1)
   05205 Proteoglycans in cancer
    136130428 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    136130428 (IGF1)
   05218 Melanoma
    136130428 (IGF1)
   05215 Prostate cancer
    136130428 (IGF1)
   05224 Breast cancer
    136130428 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    136130428 (IGF1)
   05414 Dilated cardiomyopathy
    136130428 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136130428 (IGF1)
   01522 Endocrine resistance
    136130428 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pphc04052]
    136130428 (IGF1)
Cytokines and neuropeptides [BR:pphc04052]
 Cytokines
  Growth factors (RTK binding)
   136130428 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 136130428
NCBI-ProteinID: XP_065742823
LinkDB
Position
11:19290519..19360382
AA seq 186 aa
MGKISSLPTQLFKCCFCDFLKVKMHITSSSHLFYVAVFLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYQPPSTNKKKKSQRRRKGGPKKHQGGEQKEGTEASQQADERKEERA
EEGDWS
NT seq 561 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacatcacgtcctcctcgcatctcttctacgtggccgtgttcttgctt
accttcaccagctctgccacggctggacccgagaccctctgtggggctgagctggtggac
gcccttcagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtatggc
tcgagcagtcggagggcgcctcagacaggaatcgtggatgaatgctgcttccggagctgt
gatctgaggaggctggagatgtactgcgcgcctctcaagcctgccaagtcagcccgctct
gtccgtgcccagcgccacaccgacatgcccaaggctcagaagtatcagcccccatccacc
aacaagaaaaagaagtctcaaaggagaaggaaaggtgggccaaagaaacatcaaggaggg
gaacagaaggaggggacagaagcaagtcagcaagcagatgaaaggaaagaagaaagagca
gaggagggagactggagctag

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