Phocoena phocoena (harbor porpoise): 136134047
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Entry
136134047 CDS
T11058
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00140
Steroid hormone biosynthesis
pphc01100
Metabolic pathways
pphc05215
Prostate cancer
Module
pphc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
136134047 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
136134047 (SRD5A2)
Enzymes [BR:
pphc01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
136134047 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
136134047
NCBI-ProteinID:
XP_065747558
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Position
14:64979890..65051168
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AA seq
254 aa
AA seq
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MSVRCQESPVLAGSATLAVLGALVLCLAEPAGYGKYTESRMPVATRLSARAAWFLQELPS
FAVPAGILAGQPRSLFGQPATVLLGLFCAHYFHRTFVYSLLTRGRPFPVVFLFRGFVFCM
GNGLLQGYYLVYCAEYPAEWYTDIRFGLGVVLFILGMGINIHSDYILRQLRKPGEIIYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPVIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgtccgttcgctgccaggagagtccggtgctggcaggcagcgccactttggccgtcctg
ggggcactggttctgtgcctcgcggagcccgccggctacgggaagtacacggagagccgg
atgcccgtggctacccgcctgtccgcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatccttgccgggcagccccgctctctcttcggccagcctgcg
actgtgcttctgggcctcttctgcgcacattacttccacaggacatttgtttactcactg
ctcactagagggaggccgtttccagttgtattccttttcagaggctttgttttctgcatg
ggaaatggactcctccaaggctactatctggtttactgtgctgaataccctgctgagtgg
tacacagacatacggtttggcttgggtgtcgtcttatttattttgggaatgggaatcaac
attcatagtgactatatattgcgccagctcaggaagcctggagaaatcatctataggatt
ccacaaggtggcttgttcacgtacgtttctggagccaatttccttggcgagatcattgaa
tggatcggctatgccctggccacttggtccctcccagcacttgcatttgcatttttctca
ctttgtttccttgggctgcgagcttttcaccaccatagattctacctcaagatgtttgag
gactaccccaagtctcggaaagccctcattccagtcatcttttaa
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