KEGG   Phocoena phocoena (harbor porpoise): 136136626
Entry
136136626         CDS       T11058                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc04010  MAPK signaling pathway
pphc04020  Calcium signaling pathway
pphc04022  cGMP-PKG signaling pathway
pphc04114  Oocyte meiosis
pphc04218  Cellular senescence
pphc04310  Wnt signaling pathway
pphc04360  Axon guidance
pphc04370  VEGF signaling pathway
pphc04380  Osteoclast differentiation
pphc04625  C-type lectin receptor signaling pathway
pphc04650  Natural killer cell mediated cytotoxicity
pphc04658  Th1 and Th2 cell differentiation
pphc04659  Th17 cell differentiation
pphc04660  T cell receptor signaling pathway
pphc04662  B cell receptor signaling pathway
pphc04720  Long-term potentiation
pphc04724  Glutamatergic synapse
pphc04728  Dopaminergic synapse
pphc04921  Oxytocin signaling pathway
pphc04922  Glucagon signaling pathway
pphc04924  Renin secretion
pphc05010  Alzheimer disease
pphc05014  Amyotrophic lateral sclerosis
pphc05020  Prion disease
pphc05022  Pathways of neurodegeneration - multiple diseases
pphc05031  Amphetamine addiction
pphc05152  Tuberculosis
pphc05163  Human cytomegalovirus infection
pphc05166  Human T-cell leukemia virus 1 infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05170  Human immunodeficiency virus 1 infection
pphc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pphc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136136626 (PPP3CB)
   04310 Wnt signaling pathway
    136136626 (PPP3CB)
   04370 VEGF signaling pathway
    136136626 (PPP3CB)
   04020 Calcium signaling pathway
    136136626 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    136136626 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    136136626 (PPP3CB)
   04218 Cellular senescence
    136136626 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    136136626 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    136136626 (PPP3CB)
   04660 T cell receptor signaling pathway
    136136626 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    136136626 (PPP3CB)
   04659 Th17 cell differentiation
    136136626 (PPP3CB)
   04662 B cell receptor signaling pathway
    136136626 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    136136626 (PPP3CB)
   04921 Oxytocin signaling pathway
    136136626 (PPP3CB)
   04924 Renin secretion
    136136626 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    136136626 (PPP3CB)
   04728 Dopaminergic synapse
    136136626 (PPP3CB)
   04720 Long-term potentiation
    136136626 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    136136626 (PPP3CB)
   04380 Osteoclast differentiation
    136136626 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136136626 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136136626 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    136136626 (PPP3CB)
   05163 Human cytomegalovirus infection
    136136626 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136136626 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    136136626 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136136626 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    136136626 (PPP3CB)
   05020 Prion disease
    136136626 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    136136626 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    136136626 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136136626 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pphc01009]
    136136626 (PPP3CB)
Enzymes [BR:pphc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     136136626 (PPP3CB)
Protein phosphatases and associated proteins [BR:pphc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     136136626 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 136136626
NCBI-ProteinID: XP_065750920
LinkDB
Position
16:59314975..59361322
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHGAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgagtcgtcaaagctgtccctttccccccaacgcatcgcttgacatct
gaagaagtttttgatatggatgggatacccagggttgatgttttgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatt
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctcttgctgcactttta
aaccaacaatttctttgcgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtctgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacaatttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaacttatgactgaaggagaagaccagtttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagggtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttagctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccaccccggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggactggc
aaccatggtgcccagtga

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