KEGG   Phocoena phocoena (harbor porpoise): 136138033
Entry
136138033         CDS       T11058                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc04010  MAPK signaling pathway
pphc04015  Rap1 signaling pathway
pphc04218  Cellular senescence
pphc04380  Osteoclast differentiation
pphc04620  Toll-like receptor signaling pathway
pphc04664  Fc epsilon RI signaling pathway
pphc04668  TNF signaling pathway
pphc04750  Inflammatory mediator regulation of TRP channels
pphc04912  GnRH signaling pathway
pphc04935  Growth hormone synthesis, secretion and action
pphc04936  Alcoholic liver disease
pphc05014  Amyotrophic lateral sclerosis
pphc05022  Pathways of neurodegeneration - multiple diseases
pphc05132  Salmonella infection
pphc05135  Yersinia infection
pphc05145  Toxoplasmosis
pphc05161  Hepatitis B
pphc05163  Human cytomegalovirus infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05169  Epstein-Barr virus infection
pphc05170  Human immunodeficiency virus 1 infection
pphc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pphc05417  Lipid and atherosclerosis
pphc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136138033 (MAP2K6)
   04015 Rap1 signaling pathway
    136138033 (MAP2K6)
   04668 TNF signaling pathway
    136138033 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    136138033 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    136138033 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    136138033 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    136138033 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    136138033 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136138033 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136138033 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136138033 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136138033 (MAP2K6)
   05161 Hepatitis B
    136138033 (MAP2K6)
   05163 Human cytomegalovirus infection
    136138033 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136138033 (MAP2K6)
   05169 Epstein-Barr virus infection
    136138033 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136138033 (MAP2K6)
   05135 Yersinia infection
    136138033 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136138033 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    136138033 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    136138033 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136138033 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    136138033 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136138033 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pphc01001]
    136138033 (MAP2K6)
Enzymes [BR:pphc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     136138033 (MAP2K6)
Protein kinases [BR:pphc01001]
 Serine/threonine kinases: STE group
  STE7 family
   136138033 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 136138033
NCBI-ProteinID: XP_065752620
LinkDB
Position
19:2358215..2481433
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFADFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagagaaaccctggccttaaaatcccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggagcctatagtggagctgggc
cggggggcgtacggggtggtggagaagatgcggcatgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggttactgatggatttg
gatatttccatgaggaccgtggactgtccttttacggtcaccttttatggcgcactcttc
cgtgagggggatgtctggatctgcatggagctcatggacacgtccctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctctcggtcattcatcgagatgtc
aagccttccaatgtgctcatcaacaccctgggccaggtgaagatgtgcgattttggaatc
agcggctaccttgttgactccgtcgctaaaactatcgatgcaggatgcaaaccgtacatg
gcccccgagagaataaacccagagctcaaccagaagggatacagcgtgaagtccgacatt
tggagtctgggcatcaccatgatcgagctggccatcctccggtttccctatgattcgtgg
ggaactccttttcagcagctcaaacaggtggtggaggagccgtcgccacaactccctgca
gacaagttctccgaagagtttgctgactttacctcacagtgcttgaagaagaattccaaa
gagaggccaacatatccagagcttatgcaacatccatttttcaccctacacgaatccaaa
gcgacagacgtggcatcttttgtaaaatcgattcttggagactaa

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