KEGG   Phocoena phocoena (harbor porpoise): 136138066
Entry
136138066         CDS       T11058                                 
Symbol
PTGS2
Name
(RefSeq) prostaglandin G/H synthase 2
  KO
K11987  prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc00590  Arachidonic acid metabolism
pphc01100  Metabolic pathways
pphc04064  NF-kappa B signaling pathway
pphc04148  Efferocytosis
pphc04370  VEGF signaling pathway
pphc04625  C-type lectin receptor signaling pathway
pphc04657  IL-17 signaling pathway
pphc04668  TNF signaling pathway
pphc04723  Retrograde endocannabinoid signaling
pphc04726  Serotonergic synapse
pphc04913  Ovarian steroidogenesis
pphc04921  Oxytocin signaling pathway
pphc04923  Regulation of lipolysis in adipocytes
pphc05010  Alzheimer disease
pphc05022  Pathways of neurodegeneration - multiple diseases
pphc05140  Leishmaniasis
pphc05163  Human cytomegalovirus infection
pphc05165  Human papillomavirus infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05200  Pathways in cancer
pphc05204  Chemical carcinogenesis - DNA adducts
pphc05206  MicroRNAs in cancer
pphc05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    136138066 (PTGS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    136138066 (PTGS2)
   04064 NF-kappa B signaling pathway
    136138066 (PTGS2)
   04668 TNF signaling pathway
    136138066 (PTGS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    136138066 (PTGS2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    136138066 (PTGS2)
   04657 IL-17 signaling pathway
    136138066 (PTGS2)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    136138066 (PTGS2)
   04913 Ovarian steroidogenesis
    136138066 (PTGS2)
   04921 Oxytocin signaling pathway
    136138066 (PTGS2)
  09156 Nervous system
   04726 Serotonergic synapse
    136138066 (PTGS2)
   04723 Retrograde endocannabinoid signaling
    136138066 (PTGS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136138066 (PTGS2)
   05206 MicroRNAs in cancer
    136138066 (PTGS2)
   05204 Chemical carcinogenesis - DNA adducts
    136138066 (PTGS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    136138066 (PTGS2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    136138066 (PTGS2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136138066 (PTGS2)
   05165 Human papillomavirus infection
    136138066 (PTGS2)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    136138066 (PTGS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136138066 (PTGS2)
   05022 Pathways of neurodegeneration - multiple diseases
    136138066 (PTGS2)
Enzymes [BR:pphc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.1  prostaglandin-endoperoxide synthase
     136138066 (PTGS2)
SSDB
Motif
Pfam: An_peroxidase EGF
Other DBs
NCBI-GeneID: 136138066
NCBI-ProteinID: XP_065752674
LinkDB
Position
1:complement(142373891..142380182)
AA seq 604 aa
MLARALLLCAALALCGAANPCCSSPCQNRGVCMSIGFDQYKCDCTRTGFYGENCTTPEFL
TRIKLFLKPTPNTVHYILTHFKGVWNIVNNIPFLQNMIMRYVLISRSHLIDSPPTYNVHY
GYKSWEAFSNLSYYTRVLPPVPDDCPTPMGVKGRKELPDSKEVVEKVLLRRKFIPDPQGT
NMMFAFFAQHFTHQFFKTDHKRGPAFTTGQSHGVDLNHVYGESLERQHKLRLFKDGKMKY
QIIGGEMYPPTVKDTQVEMIYPPHVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKHEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDTFQIDGQDYKYQQFVYNNSLLLEHGLTQFVESFTRQIAGRV
AGGRNLPVAVEKVSKASIDHSREMKYQSFNEYRKRFLLKPYKSFEELTGEKEMAAELEVL
YGDIDAMELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNPICSPEYWKPSTFGGEV
GFKIIKTASIQSLICNNVKGCPFTSFSVQDPQLTKTVTINASSSHSGLDDINPTVLLKER
SAEL
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgcttgcccgcgcgctgctgctctgcgccgccctggcgctctgtggtgcagcaaatcct
tgctgttccagtccatgccagaatcgaggtgtatgtatgagcataggatttgaccagtat
aaatgtgactgtacccgaacaggattctatggtgaaaactgtaccacacctgaatttctg
acaagaataaaattattcctgaaacccactccaaacacagtgcactacatacttacgcac
ttcaagggagtctggaacattgtcaataacattcccttcctgcagaatatgattatgaga
tatgtgttgatatcgagatcacatctgattgacagcccgccaacttataatgtgcactac
ggctataaaagctgggaagccttttctaacctgtcctattacaccagagttcttcctcct
gtgcctgatgactgcccaacacccatgggtgtcaaagggaggaaagagcttcctgattca
aaagaagttgtggaaaaagtacttctaagaagaaagttcatccctgatccccagggcaca
aatatgatgtttgcgttctttgcccagcacttcacccatcaatttttcaagacagatcat
aagcgaggaccagctttcaccacgggacagagccatggggtggacttaaatcatgtttac
ggtgaatctttggagagacagcataaactgcgccttttcaaggatggaaaaatgaaatat
cagataattggtggtgaaatgtatcctcccacagtcaaagatactcaggtcgagatgatc
tacccgcctcatgttcctgaacacctgcggtttgctgtggggcaggaagtctttggtctg
gtgcctggtctgatgatgtatgccacaatttggctgcgggaacacaacagagtgtgtgat
gttcttaaacatgagcatccagaatgggacgatgagcggttgttccagacaagtaggcta
atactgataggagaaactattaagattgtgattgaagactatgtacagcacctgagtggc
tatcacttcaaactgaagtttgacccagagctgctttttaaccaacaattccagtaccaa
aaccgtattgctgctgagtttaacacactctaccactggcatccccttctgcctgacacc
tttcagattgatggccaggactacaagtatcagcaatttgtctataacaactccctctta
ctggaacacggcctcactcagtttgttgaatcatttaccaggcaaattgctggcagggtt
gctggtggtaggaatcttccagttgcagtagagaaagtatcaaaggcttcaattgaccac
agcagagagatgaaataccagtcttttaatgagtaccgcaaacgctttctgctgaagcct
tataaatcatttgaagaacttacaggagagaaggaaatggctgcggagttagaagtgctc
tacggtgacattgatgccatggagctgtatcctgctcttctggtagaaaagcctcgacca
gacgccatctttggggagaccatggtagaagttggagcaccattctccttgaaaggactt
atgggtaatcctatatgttctcctgagtactggaagcctagcacttttggtggagaagta
ggttttaaaatcatcaagactgcctcaattcagtctctcatctgcaataatgtgaaaggc
tgtccttttacctcattcagtgttcaagatccacagctcaccaaaacagtcaccattaat
gcaagctcttcccactctggactagatgatatcaaccccacagtactactaaaagaacgt
tcagctgaactgtag

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