KEGG   Phocoena phocoena (harbor porpoise): 136138072
Entry
136138072         CDS       T11058                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc04010  MAPK signaling pathway
pphc04012  ErbB signaling pathway
pphc04620  Toll-like receptor signaling pathway
pphc04664  Fc epsilon RI signaling pathway
pphc04668  TNF signaling pathway
pphc04912  GnRH signaling pathway
pphc04926  Relaxin signaling pathway
pphc04935  Growth hormone synthesis, secretion and action
pphc04936  Alcoholic liver disease
pphc05132  Salmonella infection
pphc05135  Yersinia infection
pphc05142  Chagas disease
pphc05161  Hepatitis B
pphc05166  Human T-cell leukemia virus 1 infection
pphc05167  Kaposi sarcoma-associated herpesvirus infection
pphc05169  Epstein-Barr virus infection
pphc05208  Chemical carcinogenesis - reactive oxygen species
pphc05417  Lipid and atherosclerosis
pphc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136138072 (MAP2K4)
   04012 ErbB signaling pathway
    136138072 (MAP2K4)
   04668 TNF signaling pathway
    136138072 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    136138072 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    136138072 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    136138072 (MAP2K4)
   04926 Relaxin signaling pathway
    136138072 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    136138072 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    136138072 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136138072 (MAP2K4)
   05161 Hepatitis B
    136138072 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136138072 (MAP2K4)
   05169 Epstein-Barr virus infection
    136138072 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136138072 (MAP2K4)
   05135 Yersinia infection
    136138072 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    136138072 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136138072 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    136138072 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136138072 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pphc01001]
    136138072 (MAP2K4)
Enzymes [BR:pphc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     136138072 (MAP2K4)
Protein kinases [BR:pphc01001]
 Serine/threonine kinases: STE group
  STE7 family
   136138072 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 136138072
NCBI-ProteinID: XP_065752682
LinkDB
Position
19:54506328..54611552
AA seq 408 aa
MAAPSPSGGGGSGGGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFANP
PFKSTARFTLNPNPAGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRG
AYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFRE
GDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIK
PSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVW
SLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKD
ESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1227 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcaccccgggc
cccgtggggtccccggcgcccggccacccggccgtcagcagcatgcagggctttcagata
aacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgcaaatcca
cctttcaaatctacagcaaggtttactctgaatcccaatcctgcaggagttcaaaaccca
cacatagagagactgagaacacacagcattgaatcgtcaggaaaactgaagatctcccct
gagcagcactgggatttcactgcagaggacttgaaagaccttggagaaattggacgagga
gcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggcggttaaa
agaattcggtcaacagtggatgaaaaagagcaaaaacaacttctcatggatttggatgta
gtgatgcgaagtagtgattgcccgtacattgttcagttttatggtgcactcttcagagag
ggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttacaaatat
gtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcactttagca
actgtgaaagcactaaaccacttaaaagaaaacttgaaaatcattcacagagatatcaaa
ccttccaatattcttctggatagaagtggaaatattaaactctgcgactttggcatcagt
ggacagcttgtggactccattgccaagacaagagatgctggatgcaggccatacatggca
cctgaaagaatagacccaagtgcgtcacgacaaggatatgacgtccgctctgatgtctgg
agtttggggatcacattgtacgaattggccacaggccgatttccttatccaaagtggaat
agtgtgtttgatcaactaacacaagttgtgaaaggagacccaccacagttgagtaattct
gaggaaagggaattttccccaagtttcatcaactttgtcaacttgtgccttaccaaggat
gaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatgtatgaa
gagcgcgctgtcgaggttgcatgctatgtttgtaaaatcctggatcaaatgccagctact
cccagctctcccatgtatgtcgactga

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