Phocoena phocoena (harbor porpoise): 136138279
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Entry
136138279 CDS
T11058
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc03440
Homologous recombination
pphc03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
136138279 (TOP3A)
03460 Fanconi anemia pathway
136138279 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pphc03032
]
136138279 (TOP3A)
03400 DNA repair and recombination proteins [BR:
pphc03400
]
136138279 (TOP3A)
Enzymes [BR:
pphc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
136138279 (TOP3A)
DNA replication proteins [BR:
pphc03032
]
Eukaryotic type
DNA Topoisomerases
136138279 (TOP3A)
DNA repair and recombination proteins [BR:
pphc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
136138279 (TOP3A)
FA (Fanconi anemia) pathway
136138279 (TOP3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
zf-C2H2_10
Zn_ribbon_GRF_2
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
136138279
NCBI-ProteinID:
XP_065752998
LinkDB
All DBs
Position
19:58708765..58733775
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AA seq
996 aa
AA seq
DB search
MIFPVVRRALRWLPRPGSRALTLADMEVALRGVRKILCVAEKNDAAKGIADLLSGGRMRR
REGLSRFNKIYEFDYRLRGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFLDIKKTLEREARQCQVLVIWTDCDREGENIGFEIIHVCKAVKPSLQVLRARFSE
ITARAVQAACENLMEPDRRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPETFHKIRVTHDHRDGAVEFSWKRHRLFNHTACLVLY
QLCMEDPRATVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLDLTALVEEQTHDPRWGPFAQSILERGGPTPRNGNKSDQAHPPIHPT
KYTDSLQGDEQRLYELIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLVILARNYLDV
YPYDRWSEKTLPVYSRGSCFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKLVVLQQQVQKYKQVFIEAMAKAQRLDEALSQYFGAGVELAQQEAIFPAVPEPVRKCPQ
CGKDMVLKTRKSGGFYLSCTGFPECRSAVWFPDSVLEASRDGSVCPVCQPHPVYRLKFKF
KRGSLPPTMPLEFVGCVGGCDETLREILDLRFSRGPARAGQPVSQPSGHLQASQPLDRMG
SSQHGHPQPALARTAPLPAAEGEGNSVTCNCGREALLLTVRKEGPNQGRQFYKCSGGGCS
FFLWADSGHPEAGGPPSEAPRPPGGSLGRPPGSGKPLGGPGSPGDGGGGACCLCSQPAVT
RTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGTFGGPPWAGARGGSRGPEARSK
RARAGSSDAGSAAKKPRKCSLCHQPGHTRPFCPQNR
NT seq
2991 nt
NT seq
+upstream
nt +downstream
nt
atgatcttccctgtcgtccgccgcgcgctccgctggctgccgcggcctgggagccgggcg
ctgaccctcgccgacatggaggtggccctgcgaggcgtgcggaagatcctctgcgtggcc
gagaagaacgacgcggccaagggcatcgcggacctgttgtccgggggccgcatgcggcgg
agagaaggactttccagattcaacaagatctatgaatttgattatcgtctgcgtggccag
aatgtcaccatgataatgacttcagtctcgggacacttgctggctcatgatttccagatg
cagtttcgcaagtggcagagctgcaatcctcttgtcctctttgaagcagaaattgaaaag
tactgcccagagaattttttagacatcaagaaaactctggagcgagaggctcggcagtgc
caggtgctggtgatctggaccgactgtgacagagaaggtgaaaacatcgggtttgagatc
atccacgtgtgcaaggctgtgaagcccagcctacaggtgctgcgagcccgtttctccgag
atcaccgcccgcgctgtccaggcggcctgtgaaaacctgatggagcccgaccgcagagtg
agcgacgccgtggacgtgaggcaggagctggacctgcggatcggggctgccttcaccagg
ttccagaccctgcggctgcagaagatctttcctgaggtgttggcggagcagctgatcagt
tatggcagctgccagttccccaccctggggttcgtggtggagaggttcaaagccattcag
gcgtttgtgccagaaaccttccacaaaatcagagtgacccacgaccacagggatggcgca
gtggagttcagctggaaaaggcatcggcttttcaaccacacggcttgtcttgtcctctat
cagctgtgcatggaggatcccagggcgaccgtggtggaggtcaggtccaaggcaaaaagc
aagtggaggcctcaagctttggacactgtggagcttgagaagttggcttctcgaaagttg
aggataaatgctaaagaaaccatgaggattgctgaaaagctctacactcaagggtacatc
agctatccccgaactgaaacaaacattttccccaaagacttagacctgaccgcgctggtg
gaggaacagacccacgatccacgctgggggcccttcgcccagagcattctagagcggggc
ggccccactccacgcaacggaaacaagtctgaccaagctcaccctcccatccaccccacc
aagtacacggacagcctgcagggggacgagcagcgactgtacgagctcatcgtccgccac
ttcctggcctgctgctcccaggatgcccagggccaggagaccaccgtggagatcgacatc
gcgcaggagcgcttcgtggcccacggcctcgtaatcctggcccgaaactatctggacgtg
tacccctacgatcgctggagtgaaaagaccctccccgtctacagtcgaggctcctgcttt
cagcccagcaccgtggagatggtggacggggagaccagtccaccccagctgctcactgag
gccgaccttatcgccctcatggagaagcacggcatcggtaccgacgcgacgcacgcggag
cacatcgagaccatcaaggcccggatgtacgtcgggctcacgccagacaagcgctttctc
cccgggcacctgggcatggggcttgtggaaggctatgactccatgggctacgagatgtcc
aagcctgacctgcgggccgagctggaggctgacctgaagctcatctgcgaggggaagaag
gacaagctcgtggtcctgcagcagcaggtgcagaagtacaagcaggtcttcatcgaagcc
atggccaaagcccagaggttggacgaggccttgtcgcagtactttggggcaggggtggag
ctggcccagcaagaagccatcttcccagctgtgccagagcccgtcaggaagtgcccacag
tgcggcaaggacatggtcctcaagaccaggaagagcggcgggttctacctcagctgcacg
gggttcccggaatgtcgctcggccgtgtggttcccggacagtgtgctggaggccagcagg
gacgggagcgtgtgtccagtgtgtcagccacaccccgtttacaggttgaagttcaagttt
aagcgaggcagccttcccccaaccatgccactggaatttgtcggctgcgttggtggatgt
gacgagaccctgagggagatcttggacctcaggttttcacgggggcccgcccgagctggc
cagccggtcagccagccctccggccacctgcaggccagccagcccctggacagaatgggc
agcagccagcacggccacccccagccggctctggccaggactgcgcccctgcccgccgct
gagggcgaaggcaactccgtgacctgcaactgtggccgggaggccctgctgctcaccgtc
cggaaggaggggcccaaccagggccgtcagttctacaagtgcagcggcggcggctgcagc
ttcttcctctgggccgacagcggccacccagaagcaggggggcctccctccgaggcgccc
agacccccgggcggctcactgggacgcccgccgggctcagggaagcccctgggcgggccc
ggaagccccggcgatggtggcggtggcgcatgctgcctgtgcagccagcccgctgtcaca
cgcactgtgcagaaggacgggcccaacaaggggcgccagttccacacgtgtgccaagccc
cgggagcagcagtgcggcttcttccagtgggtggacgagaacgtggccccagggaccttt
ggaggccccccctgggcaggagccagaggaggaagccgggggccggaggccagaagcaaa
agggcccgggctggttcctcggacgccgggtctgcggccaagaaaccccggaagtgcagc
ctttgccaccagcctggacacacgcgtcccttctgtcctcagaacagatga
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