Phocoena phocoena (harbor porpoise): 136138678 Help Entry 136138678         CDS       T11058                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism pphc  Phocoena phocoena (harbor porpoise) Pathway pphc01521   EGFR tyrosine kinase inhibitor resistance pphc04010   MAPK signaling pathway pphc04012   ErbB signaling pathway pphc04014   Ras signaling pathway pphc04015   Rap1 signaling pathway pphc04020   Calcium signaling pathway pphc04066   HIF-1 signaling pathway pphc04070   Phosphatidylinositol signaling system pphc04071   Sphingolipid signaling pathway pphc04072   Phospholipase D signaling pathway pphc04082   Neuroactive ligand signaling pphc04150   mTOR signaling pathway pphc04151   PI3K-Akt signaling pathway pphc04261   Adrenergic signaling in cardiomyocytes pphc04270   Vascular smooth muscle contraction pphc04310   Wnt signaling pathway pphc04360   Axon guidance pphc04370   VEGF signaling pathway pphc04510   Focal adhesion pphc04540   Gap junction pphc04613   Neutrophil extracellular trap formation pphc04650   Natural killer cell mediated cytotoxicity pphc04664   Fc epsilon RI signaling pathway pphc04666   Fc gamma R-mediated phagocytosis pphc04670   Leukocyte transendothelial migration pphc04713   Circadian entrainment pphc04720   Long-term potentiation pphc04723   Retrograde endocannabinoid signaling pphc04724   Glutamatergic synapse pphc04725   Cholinergic synapse pphc04726   Serotonergic synapse pphc04727   GABAergic synapse pphc04728   Dopaminergic synapse pphc04730   Long-term depression pphc04750   Inflammatory mediator regulation of TRP channels pphc04911   Insulin secretion pphc04912   GnRH signaling pathway pphc04916   Melanogenesis pphc04918   Thyroid hormone synthesis pphc04919   Thyroid hormone signaling pathway pphc04921   Oxytocin signaling pathway pphc04925   Aldosterone synthesis and secretion pphc04926   Relaxin signaling pathway pphc04928   Parathyroid hormone synthesis, secretion and action pphc04929   GnRH secretion pphc04933   AGE-RAGE signaling pathway in diabetic complications pphc04935   Growth hormone synthesis, secretion and action pphc04960   Aldosterone-regulated sodium reabsorption pphc04961   Endocrine and other factor-regulated calcium reabsorption pphc04970   Salivary secretion pphc04971   Gastric acid secretion pphc04972   Pancreatic secretion pphc05017   Spinocerebellar ataxia pphc05022   Pathways of neurodegeneration - multiple diseases pphc05031   Amphetamine addiction pphc05032   Morphine addiction pphc05143   African trypanosomiasis pphc05146   Amoebiasis pphc05161   Hepatitis B pphc05163   Human cytomegalovirus infection pphc05164   Influenza A pphc05170   Human immunodeficiency virus 1 infection pphc05171   Coronavirus disease - COVID-19 pphc05200   Pathways in cancer pphc05205   Proteoglycans in cancer pphc05206   MicroRNAs in cancer pphc05207   Chemical carcinogenesis - receptor activation pphc05214   Glioma pphc05223   Non-small cell lung cancer pphc05225   Hepatocellular carcinoma pphc05231   Choline metabolism in cancer pphc05415   Diabetic cardiomyopathy pphc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pphc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     136138678 (PRKCA)    04012 ErbB signaling pathway     136138678 (PRKCA)    04014 Ras signaling pathway     136138678 (PRKCA)    04015 Rap1 signaling pathway     136138678 (PRKCA)    04310 Wnt signaling pathway     136138678 (PRKCA)    04370 VEGF signaling pathway     136138678 (PRKCA)    04066 HIF-1 signaling pathway     136138678 (PRKCA)    04020 Calcium signaling pathway     136138678 (PRKCA)    04070 Phosphatidylinositol signaling system     136138678 (PRKCA)    04072 Phospholipase D signaling pathway     136138678 (PRKCA)    04071 Sphingolipid signaling pathway     136138678 (PRKCA)    04151 PI3K-Akt signaling pathway     136138678 (PRKCA)    04150 mTOR signaling pathway     136138678 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     136138678 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     136138678 (PRKCA)    04540 Gap junction     136138678 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     136138678 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     136138678 (PRKCA)    04664 Fc epsilon RI signaling pathway     136138678 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     136138678 (PRKCA)    04670 Leukocyte transendothelial migration     136138678 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     136138678 (PRKCA)    04929 GnRH secretion     136138678 (PRKCA)    04912 GnRH signaling pathway     136138678 (PRKCA)    04921 Oxytocin signaling pathway     136138678 (PRKCA)    04926 Relaxin signaling pathway     136138678 (PRKCA)    04935 Growth hormone synthesis, secretion and action     136138678 (PRKCA)    04918 Thyroid hormone synthesis     136138678 (PRKCA)    04919 Thyroid hormone signaling pathway     136138678 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     136138678 (PRKCA)    04916 Melanogenesis     136138678 (PRKCA)    04925 Aldosterone synthesis and secretion     136138678 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     136138678 (PRKCA)    04270 Vascular smooth muscle contraction     136138678 (PRKCA)   09154 Digestive system    04970 Salivary secretion     136138678 (PRKCA)    04971 Gastric acid secretion     136138678 (PRKCA)    04972 Pancreatic secretion     136138678 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     136138678 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     136138678 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     136138678 (PRKCA)    04727 GABAergic synapse     136138678 (PRKCA)    04725 Cholinergic synapse     136138678 (PRKCA)    04728 Dopaminergic synapse     136138678 (PRKCA)    04726 Serotonergic synapse     136138678 (PRKCA)    04720 Long-term potentiation     136138678 (PRKCA)    04730 Long-term depression     136138678 (PRKCA)    04723 Retrograde endocannabinoid signaling     136138678 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     136138678 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     136138678 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     136138678 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     136138678 (PRKCA)    05206 MicroRNAs in cancer     136138678 (PRKCA)    05205 Proteoglycans in cancer     136138678 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     136138678 (PRKCA)    05231 Choline metabolism in cancer     136138678 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     136138678 (PRKCA)    05214 Glioma     136138678 (PRKCA)    05223 Non-small cell lung cancer     136138678 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     136138678 (PRKCA)    05161 Hepatitis B     136138678 (PRKCA)    05171 Coronavirus disease - COVID-19     136138678 (PRKCA)    05164 Influenza A     136138678 (PRKCA)    05163 Human cytomegalovirus infection     136138678 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     136138678 (PRKCA)    05143 African trypanosomiasis     136138678 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     136138678 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     136138678 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     136138678 (PRKCA)    05032 Morphine addiction     136138678 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     136138678 (PRKCA)    05415 Diabetic cardiomyopathy     136138678 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     136138678 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     136138678 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pphc01001]     136138678 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pphc04131]     136138678 (PRKCA) Enzymes [BR:pphc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      136138678 (PRKCA) Protein kinases [BR:pphc01001]  Serine/threonine kinases: AGC group   PKC family [OT]    136138678 (PRKCA) Membrane trafficking [BR:pphc04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     136138678 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 Motif Other DBs NCBI-GeneID:  136138678 NCBI-ProteinID:  XP_065753559 LinkDB All DBs Position 19:complement(521227..885577) Genome browser AA seq 670 aa AA seqDB search MADVFPANDSAAPQDVANRFARKGALRQKNVHEVKDHRFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTEEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE LRQKFEKAKLGPAGNKVISPDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTE ELYAIKILKKDVVIQDDDVECTLVEKRVLALPDKPPFLTQLHSCFQTVDRLYFVMEYVNG GDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADF GMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGED EDELFQSIMEHNVSYPKSLSREAVSICKGLMTKHPGKRLGCGPEGERDVREHTFFRRIDW EKLENREVQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQ FVHPILQSTV NT seq 2013 nt NT seq  +upstreamnt  +downstreamnt atggctgacgtcttcccggccaacgactcggcggcgcctcaggacgtggccaaccgcttc gcccgcaaaggggcgctaagacagaagaacgtgcacgaggtgaaggaccaccgcttcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgactttatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgttactttttcttgtccgggtgcagataaaggacctgacactgatgaccccaggagc aagcacaaattcaagatccacacctatggaagccccaccttctgcgatcactgtgggtcg ctgctgtacgggctcatccatcaggggatgaagtgtgacacctgtgatatgaacgtgcac aagcagtgcgtgataaacgtccccagcctctgcgggatggaccacacggagaagaggggc cggatctacctgaaggccgaggtcaccgaggaaaagctccacgtcacagtacgagatgca aaaaatctcatccctatggatccaaatgggctttcagatccttatgtgaagctgaagctt attcctgaccccaagaacgaaagcaaacaaaaaaccaaaaccatccgttccacactgaac ccccagtggaatgagtcctttacattcaaattaaaaccttcggataaagaccgacgactg tccgtagagatctgggactgggatcgaacaaccaggaacgacttcatggggtccctttcc ttcggagtctcggagctgatgaagatgccggccagtggatggtacaagttgctgaaccaa gaagagggtgagtactacaacgtgcccattccagaaggcgatgaggaaggcaacgcggag ctgaggcagaagttcgagaaagccaagctcggccctgctggcaacaaagtcattagtcct gacaggagacagccttccaacaacctcgacagagtgaaactcaccgacttcaacttcctc atggtgctgggcaagggcagcttcgggaaggtgatgctggcggacaggaaggggacggag gagctgtacgccattaagatattgaagaaggacgtggtgatccaggacgacgatgtggag tgcaccctggtggagaagcgggtgctggccctgccggacaagcccccgttcctgacgcag ctgcactcctgcttccagacggtggatcggctgtacttcgtcatggaatacgtcaatggc ggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccgcaagcagtgttc tacgcagcagagatttccattgggttgttctttcttcataaaagaggcatcatttataga gacctgaagttagataacgtcatgctggattcggaaggacatatcaagattgcggacttt gggatgtgtaaggagcacatgatggacggggtgacgaccaggaccttctgcgggaccccg gattacatcgccccggagataatcgcttatcagccgtatgggaaatccgtggactggtgg gcctacggcgtcctgttatatgaaatgctggccgggcagcctccatttgacggcgaggat gaagacgagctgtttcagtccatcatggagcacaacgtctcgtacccgaagtccttgtcc agggaggccgtctccatctgcaaagggctgatgaccaaacaccccggcaagcggctgggc tgcggacccgagggagagcgggacgtgcgggaacacaccttcttccggaggatcgactgg gagaagctggagaacagggaggtccagccgcccttcaagcccaaagtgtgcggcaaagga gcagaaaacttcgacaagttcttcacgcgagggcagcctgtcttaacaccgcctgatcag ctggtcatcgctaacatcgaccagtctgattttgaagggttctcctatgtcaacccccag ttcgtgcaccccatcctacagagcacagtatga

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