Phocoena phocoena (harbor porpoise): 136139033
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Entry
136139033 CDS
T11058
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04140
Autophagy - animal
pphc04141
Protein processing in endoplasmic reticulum
pphc04210
Apoptosis
pphc04932
Non-alcoholic fatty liver disease
pphc05010
Alzheimer disease
pphc05012
Parkinson disease
pphc05014
Amyotrophic lateral sclerosis
pphc05016
Huntington disease
pphc05017
Spinocerebellar ataxia
pphc05022
Pathways of neurodegeneration - multiple diseases
pphc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
136139033 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
136139033 (ERN1)
09143 Cell growth and death
04210 Apoptosis
136139033 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
136139033 (ERN1)
05012 Parkinson disease
136139033 (ERN1)
05014 Amyotrophic lateral sclerosis
136139033 (ERN1)
05016 Huntington disease
136139033 (ERN1)
05017 Spinocerebellar ataxia
136139033 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
136139033 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
136139033 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
136139033 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pphc01001
]
136139033 (ERN1)
Enzymes [BR:
pphc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
136139033 (ERN1)
Protein kinases [BR:
pphc01001
]
Serine/threonine kinases: Other
IRE family
136139033 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
136139033
NCBI-ProteinID:
XP_065754029
LinkDB
All DBs
Position
19:14396521..14448304
Genome browser
AA seq
960 aa
AA seq
DB search
MPKIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLP
DPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEK
QQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAAALPEDDVEYKM
SHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTF
MSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPL
LEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLHNYWLLIGHHETPLSASTKM
LERFPNNLPKHRENVIPADSEKKSFEEVIDLVDQTSENAPTTVSPDVEEKFAHVPPRPEA
PVDSMLKDMATIILSTFLLIGWVAFIITYPLSRRQQRQLQHQRFQKELEKIQLLQQQQLP
FHPPGDVAAQDTDLLDSCGQYSESSATSSPSTSPRVSNHSLHSSGSTSRAATGPFPEQDD
EDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLL
RESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGL
AHLHSLNIVHRDLKPHNILLSMPSAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEG
WIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLH
PEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDG
PIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPE
EVRETLGPLPDGFVRYFTSRFPHLLSHTYRAMELCRRERPFQPYYHEPPEPRPPVTPDAL
NT seq
2883 nt
NT seq
+upstream
nt +downstream
nt
atgcccaagatttttggaagtcccagcactgtgacacttcctgaaaccttgttgtttgta
tcaaccctggacggaagtttgcatgctgtcagcaagaggacaggctcaatcaaatggact
ttgaaagaagatccagtcctgcaggttccaacacacgtggaagagcctgcattcctccca
gatcccaacgatggcagcctgtatacgcttgggggcaagaataatgaaggcctgacgaaa
cttccctttacgatcccagagttggtgcaggcatccccgtgccggagttcggatggaatt
ctctacatgggtaaaaagcaggacatctggtacgtcattgacctcctgaccggggagaaa
cagcagactttgtcatcggcctttgcggatagtctctgcccatcaacctctcttctgtat
cttgggcgaacagagtacaccatcaccatgtacgacaccaaaacccgcgagctccggtgg
aacgccacctacttcgactacgcagctgctctgcccgaggacgacgtggaatataaaatg
tcccactttgtgtccaatggcgatgggctggtggtgaccgtggacagcgaatctggggac
gtcctgtggatccaaaactacgcttcccccgtggtggctttttacatctggcagcgggag
ggcctgcggaaggtggtacacatcaacgtcgctgtggagaccctgcgctacctgaccttc
atgtcgggggaggtggggcgcatcaccaagtggaagtacccgttccccaaggagacggag
gccaagagcaagctgatgcccaccctgtatgtggggaaatactctaccagcctctacgct
tccccctcaatggtacacgagggggtcgccgttgtgccccgaggcagcacccttcctttg
ctggaaggaccccagaccgacggtgtcaccatcggggacaaaggggagtgtgtgatcaca
cccagcacggacctgaagttcgaccctgggctcaaggggaagagcaagctcaactacctg
cacaactactggctgctcatcggacaccacgagaccccactgtctgcatctaccaagatg
ctggagcgattccccaacaatctgcccaaacaccgggaaaatgtgattcctgctgactca
gagaaaaagagctttgaggaggttatcgacctggttgaccagacttcagaaaacgcaccc
accacagtttctccagatgtggaagagaagttcgctcatgtcccacccaggcccgaggcc
cccgtggactccatgctcaaggacatggccaccatcatcctgagcaccttcctgctcatt
ggctgggtggccttcatcatcacctaccccctgagcagacgtcagcagcggcagctccag
caccagcggtttcagaaggaactggagaagatccagctcctgcaacagcagcaactgccc
ttccacccacctggagacgtcgcagcccaggacaccgacctcctggactcgtgcggacag
tactcggagagctcggccaccagcagccccagcacgtcccccagagtctccaaccactcg
ctccactccagcggctccacctccagggccgccaccggccccttcccggagcaggatgac
gaggatgaggaaaccagcatggtgatagttgggaaaatctcattctgtccgaaggacgtc
ctgggccacggagccgagggcacaattgtgtaccgtggcatgtttgacaaccgcgacgtg
gccgtcaagaggatcctccccgagtgttttagtttcgcagaccgtgaggtccagctgctg
cgagagtcagacgagcacccaaacgtgatccgttacttctgcaccgagagggaccggcag
ttccagtacatcgccatcgagctgtgcgcggccaccctgcaggagtacgtggagcagaaa
gactttgcccacctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctg
gcccacctgcactccctcaacatcgttcacagagacctgaagccacacaacatcctcctc
tccatgcccagcgcacacggcaggatcaaggccatgatctccgacttcggcctctgtaag
aagctggcggtgggcagacacagcttcagccgccgctcaggggtgcccggcacagaaggc
tggatcgccccggagatgctgagcgaagactgcaaggagaaccccacctacacggtggac
atcttctctgcgggctgcgtcttttactacgtgatatctgagggcagccacccttttggc
aagtccctgcagcggcaggccaacatcctcctgggcgcctgcagcctggactgcctgcac
cctgagaagcacgaagacgttattgcccgggagttaatagagaagatgattgcaatggat
cctcagaagcgcccgtcagcgaagcatgtgctgaaacacccgttcttctggagcctagaa
aagcagctccagttcttccaggacgtgagtgaccggatagagaaggagtccctagacggc
ccgatagtgaagcagctggagcgcggcgggcgggctgtggtgaagatggactggagggag
aacatcactgtccccctccagacagatctgcgtaaattcagaacctataaaggcggctct
gtccgagatctcctccgggccatgagaaataagaagcaccactaccgggagctgcctgag
gaggtgcgggagacgctaggcccccttcccgacggcttcgtgcgctacttcacctcgcgc
ttcccccacctcctctcccacacctaccgtgccatggagctgtgccgccgcgagaggccc
ttccagccctactaccacgagccccccgagccccggcccccagtgactccagacgccctc
tga
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