Phocoena phocoena (harbor porpoise): 136140338
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Entry
136140338 CDS
T11058
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00140
Steroid hormone biosynthesis
pphc01100
Metabolic pathways
pphc04913
Ovarian steroidogenesis
Module
pphc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
136140338 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
136140338 (HSD17B2)
Enzymes [BR:
pphc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
136140338 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
136140338 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
DUF1776
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
136140338
NCBI-ProteinID:
XP_065754479
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All DBs
Position
20:53063305..53128337
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AA seq
450 aa
AA seq
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MLIQGVPGLFSPPPFLPLCSNNPGCLQPVFAHLTQLALSTERRRESLRMGTFFSEPGWLC
LTVTAVLGGTIFCKLKKNQGQVGRKVVCLAGLWGGACLLSLSLFWGLILFSLSCFLVYTY
FSGQELLPADQKAVLITGGDSGIGHALSKYLDELGFTVFAGVLDEKGSGAEELRRTCSKR
LSVLQLDITDPQQIKDAHSKVKEKLQNRGLWAVVNNAGILGLPTDGELIPMTEYKRCMAV
NFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKLAAYSSSKAALTMFSAVMRQELS
KWGVKVSVIQPGGFRTNIAGTSDMWDKLEKNILDHLTPDVQEDYGQDYILRERNFLMFMQ
TYSVMDVSPVLLDIQHAISAKSPSAFYAPGKMSYLWLCFVSFSPTGIFDYFSKKILPGVE
ITVRHGEKVLNTDPGGSENPGSEKLLAGFP
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgctcattcaaggtgttccggggctgttttctccccctcccttcttgcctctctgttca
aataacccaggctgcctgcagcctgtctttgcccatttgactcaactggccctgagcacg
gaaaggagaagagagtctctgagaatgggcactttcttctctgagccaggatggctttgc
ctgactgtcaccgcagtgctaggaggaacaattttttgcaaactcaagaagaaccaaggg
caggtggggagaaaggtggtctgcctggcgggcctctggggaggggcttgcctgctcagc
ctgtccctcttctggggcttgatcctcttctccctgtcatgtttcctcgtatatacttac
ttttctggccaagagttgttacctgcagatcaaaaggcggtgctgatcacaggtggcgat
tctgggattggccatgctttgtccaagtatctggacgagttgggcttcacggtatttgct
ggagttctggatgaaaagggatctggagcagaggaattacgaagaacctgctccaagcgt
ctctccgtgctccagctggacattaccgacccgcaacagataaaagatgcccacagcaaa
gtgaaggaaaagctgcagaacagaggactgtgggctgtggtcaacaatgctgggatcctt
ggcctcccaactgacggggagctcattcccatgaccgaatacaaacgatgcatggccgtg
aacttcttcggggccgtggaagtcacaaaggcatttttgcctcttcttaggaaatccaag
gggaggctggtgaacatcagcagcatggcaggaggggttccaatggagaagttggcagcc
tatagctcatccaaggcagctctgaccatgttttcagcagtcatgagacaagagctctcc
aaatggggagttaaagtctctgtcatccagcctggaggcttccgaacaaacatcgcaggc
acgagtgacatgtgggacaagctggagaaaaacatcctggaccacctcacccctgacgtg
caagaggactacggccaggactatatccttagggaacgcaattttctcatgttcatgcaa
acctactctgtaatggacgtctccccagtcctcttggacatccagcatgccatctctgct
aagagcccctctgcattttatgcacccgggaaaatgtcttatctgtggctctgttttgtt
tcctttagccctactggcatatttgattattttagcaaaaaaatcctcccaggggttgaa
atcactgtgaggcatggggagaaggtgctgaatacagacccaggggggtctgagaatcct
ggatcagagaagctactagctggtttcccatag
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