Pleuronectes platessa (European plaice): 128454645 Help Entry 128454645         CDS       T09923                                  Symbol obscnb Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism pplt  Pleuronectes platessa (European plaice) Pathway pplt04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pplt00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     128454645 (obscnb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pplt01001]     128454645 (obscnb)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pplt04131]     128454645 (obscnb) Enzymes [BR:pplt01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      128454645 (obscnb) Protein kinases [BR:pplt01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    128454645 (obscnb) Membrane trafficking [BR:pplt04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     128454645 (obscnb) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_4 Ig_5 Ig_6 Izumo-Ig V-set_CD47 SOS1_NGEF_PH fn3 C1-set RhoGEF Ig_DSCAM-DSCAML_C PH IQ Motif Other DBs NCBI-GeneID:  128454645 NCBI-ProteinID:  XP_053294068 LinkDB All DBs Position 13:complement(8393520..8442708) Genome browser AA seq 6629 aa AA seqDB search MDPNLYGGVPRFLTRPKAFSVCAGKDATLSCTIVGSPTPLITWEKDKLKLTSGGRFKTVE DGDVYRLTIYDLTLEDGGQFMCRAKNSVGEAYAAVTVKVALPTEMAPRAPVFMMKPTSAR VGLGGDVVFHCRVAAHPEANFDWEKDGRYLGESNRIKIVSDTDGSTLKIQSLRNLDSGTY TCRAKNTVGRAHAAAALVVDAQDSHYQSADKNTSLLSHLQKRKEEMNKDISIYRTEEKSS SVSSSTTDGFSSLSLEHALRASALATLPKGVFTRTCTVTEGKHAKLSCFVTGHPKPHIIW RKDGMNIGEGRRHVIYEDQAENFILKVLYCKQTDNGLYTCNATNMAGQTYSAVLVTVKEP KVPFRRKLQDIEVQEKTSATLMCEVPVVATHAHWFMEETMLEQNTKYRMEEEGTLRRLTI HNVTTNDDGVYICEMKEGSRTVAELTVLGNITKKLPRRTVVPVSDTVIFCVELEHPYPDA YWTRKGEKLKEESRISIACVLRQYTLTIRDCQAEDSGEIAFVAGDCKTSTRFTVTAARKH PPDPPVNAVVLNKTDSSITIQWSPPDSDRPVPIKCYIVERRKVGTQTWQRCNAGETIVST EITICNFKEESSFQFRISAMNDFGQSPHLEVPGSFYLEPSAEIRKGLMDTTANSGEEFSI TIELSAVCSGYWYINGRVLRSGADYLITKSKTTHTLLFRDMTMELNGAEVKFVGGGSQSS CILSVKAPRVRFINKSDLTEVVTCTAQSTAQLTAEVSDYETQVVWMKNGREVKMGKKYEY VIIDRKRILMVHNVTEEDVGIYECVLAEDKMSLQLSLKDEPAKFLNKARGAMGMSSSLKG DLELSCEVSPASAVVVWRKDQVEITEDQRTAMVSKGTQRKLVIKNAKKSDEGHYSCETAA DKVTFQVKIKETLAVAAFSNKESVQKEVKATLWQKATLSCNVSDSKAEVKWYKDGKQLIS SRTIYSEVTGTARQLVFEKVEKSDAGEYTCEAGGDKLVFKISVSEAQAAFFNKESVQKEV KATLSQKAILSCEVADSKTEVKWYKDAKLLTSSKTIHAESKGQSRQLYIDSVEKKDAGEY ICEAGTEKLAFKIQVEEPKSFFSNKESVQKEVRATFSQKTTLSCEVSDSKTEVKWYKDGK LLTSSKTIHTESKGKSRMLVIDSAEKKDAGEYMCEVGTEKLAFKIQVEEPKSFFSNKESV QKEVKATFSQKTTLSCEVSDSKTEVKWYKDGKLLTSSKTIHTESKGKSRTLVIDSAEKKD AGEYMCEAGTEKLVFKLQASDTQIQSAFSNKDSVQKEVKATVSQKAILSCEVADTKTEVK WYKDGKLLTSSKTINAVSKGKSRQLVIDSVEKKDAGEYICEAGTEKLAFKMQVAVTSTKI GAKSGSLNNEAVQKEVKSTLLEPGNLSWEVVDNTTEVKWYKDGKLVSPSGPVALESKGKI HQLVVDSVEEKNAEEHICEVRTESLAFKEQFTEILAKSAFSKKDSVQKEVKATLTQKTIL SCEVADTKTEVKWFRDGKLLTSSKTVHAESKGLSRQLVIDSVEKKDAGEYICEAGTEKLA FKIQVAEAPAGFSNKESVQNEVKVTLSQKATLSCEVSDSKTEVKWYKDGKLLTSSKAVHM ESKGKSRELVIEKIEKKDAGEYTCETGTEKLVFRLHVTEEAVKFQKKSVKDTCIVQASEN IVLTTELTSESGSVKWLRDGVEIKEGRKYEMKKDGHCRTLIVNSTETKDSGTYSCQTAHD KQEFKVQVKESALKFVVPLKSADVELGGTLSLMCELNQASGDVVWHHIGREIKPGGRHCV RTDGAKRVLTVTDMTKEDEGEYSCECRNDKTSAKISSKEPRVVRLTTKLNNVAAMEGKDA IFKCAATPADINVKWFHNSIPITAGPKYKIEHGGNTHSLTITSVTQKDAGEISVDAEGKS CKATLQVQHEPVTFKKKLENLTVDEQSEVKMEVELSKKSDEVRWMKNSIVLQAAGNLEIR VDGAKQALVFKSVTHGDRGIYSCETLDDKTQAKLTVEMKKIKVIKGLPETKAHETETVTL EVELSQADVEGSWTRDGAKLKPGANCRITALGKKHALTLSNLKRDDAGTISFQADGVHTS GKLIVTEPPAMVSTPIIDMSVPEKEKVTFECEVSRTNADVKWFKDNVELKPGKNYGIHSL GRKRTLVISKCTPADAGSYVCRTTDDNTSAKLIVHARDIKIIKKLEDVEVMEKESAAFVC EISHDEVDCQWYKGSTKVKVSDNIKMRQEGRTYVLLFKSVSPEDMGDIKFTAEKTSSSAK LKVKELPVKFVKRLRDKIAMFKHRGYLECQVSRASAKVKWYKNKTEIKPSKKHEIRSEDV YRKLTINDVDTGDEDTYTCDATDDQTSCKLLVEEQSISIVRELSSVEVTEPFAAVFEVEI SMELVKPPIWTLNGVAVQESADAEMEKEGTLHRLTFKKTKASMTGPVQFTAGKSKSLAQL TVKERPLEIAEPIKDVKAKEKSSALFCCKFSTAAKEVNWFKGQVLLAASDKYNMKKDGTR AQLTIQGLTGEDGGEYRCQSGPAETKGTLTVEVREIKITKHLIDTEVDEDSDAVFTCEIN YADEEAQWLLKDKVLLTNEVNTISHEGKVHKLMLKNMAPQDGGTITFQVRKVKESVTLKV KEKLAVFLKSLDDVIGEEKGMITLTCEASKPRVSPIWRKEGKVLKAGPKYELLHTGKSLG LIIKDATKDDAGDYSCDLGTEVSKAKVTVREIGIGITKWLKSAEVNEGETCSFECILSRE NTDECSWSLNGKAISNGGRFNVTNKGRKYMLNIKDVTPADAGEVVFNIKDLSTKTTLTVE GRASSVSKGLQNASAVQGEDAVFSCEVTQASSTVKWAKEGKAIKKSQKYDISQEDKVMKL TIHSVSAQDSGEYSCEVVGGATTKAQLEIKEPIHKFTEVLKDSQADEKSSVTLQCETAQS PSTVIWLKGHTELKAGGRYEMSQKERVLTLTIKQLEEKDTDIYTCDVITAKNMAKVTVKA LPATFKEKLKNQDKKEGETVTLCCELSKPATDIQWKKGSEILKAGEKYEMKQKHTALELQ IKDLKVEDSGEYSCVCVDQKTSASVKVNALPPTFIQKLKTQEAEEGVDITLNCELSKPGV SVEWKKGTQVLKSGEKYQMKQKASVNELLINKVVPEDSGDYSCVCGDQTTTASLKIKAQP VTFKQKLETQEAEEGASVTLHCELSKPGVSVEWKKGTQVLKSGEKYQMKQKASVNELLIN KVVPEDTGDYSCVCGDQKTTASVKINAQPVTFKQKLETQEAEEGASVTLRCELSKPGVSV EWKKGTQVLKSGEKYQMKQKASVNELLINKVVPEDTGDYSCVCGDQKTTASVKINAQPVT FKQKLETQEAEEGASVTLHCELSKPGVSVEWKKGTQVLKSGEKYQMKQKASVNELLINKV VPEDTGDYSCVCGDQTTTASLKIKAQPVTFKQKLETQEAEEGASVTLHCELSKPGISVEW KKGTQVLKSGEKYQMKQKASVNELLINTVVPEDSGDYSCVCGDQKTTASLKIKAQPVTFK QKLETQEAEEGASVTLHCELSKPGVSVEWKKGTQVLKSGEKYQMKQKASVNELLINKVVP EDTGDYSCVCGDQTTTASLKIKAQPVTFKQKLETQEEEEGASVTLHCELSKPGVSVEWKK GTQVLKSGEKYQMKQKASVNELLINKVVPEDSGDYSCVCGDQKTTASLKINAQPVFFKTQ LQKVERQAGEIAILRCETTKPGAIVVWRHGDRELASSSKYHLKQEGTVVELVIYKLQGAD SGEYSCDTGSRRTSAVLTVHEVEITILKFLESSVVYEGEDVHFECLLSHDEAPLAQWKLQ DVPLQNNEMNLIKTENRVHSLTLRGVTTTDSGTVTFTVGNHTSTASLTVRAAAPVLFKKE LESQEATEGGKVTLSCETSSPDCKVTWHKGSSELTHGEKYTIVQGGTTHTLVIHKLKVED SGEYTSQAGDKKSTATLTVKERVRIIRELYDITVTTGQDAVFEVELSHSGVTNGEWWLAD NLLQNNDLNQMSSQGRVHRLTLKMVTTEESGDVAFVVGEEKTVACLLVEEKPKVKIVEKP HNTLVIEGETVTLACTISDPKATVTWIRNNVAIQAGLKYDLKKNGAFHQLCILNGLPEDS GVYTCDTGDVQCEVTVTVEGAPVFFRKELKNEDAVEGDDSTLRCELSKPGVCVEWRKGGI VLEPGKKYKMRQEGCIRELCISNSDPEDSGYYTCDAGDQLTTASLAVQVKEVFIVCGLKT TDVFVGEWATFSCQLSAIAPGKVQWWLDGTLLENSPFSEIGLSQGHIYTLTLKSLATDDS GTVTFKAGSLTSSSKLLVKDPTVEVVSEMQDLCVVENQPAEFICQYSRPVRAQWKKDGQP LQPDGRRVLVEQDWNVARLYISSVSTGDKGTYSCEAEGTSVVASLHVEGKPITIVQGLEN AETFDGGETLFECALSRPENKDCHWFLDGKPVKESRNVEIVSFESGRRHLLLLKELHVKD SCTVMFKAGTSSTSAQLSVKGWQLDVVKGLEDKVAAVGEKVEFCVELTEPIPVAEVAWYA NGVELKPSDLWAMRADGCSYRLVLRRAPLLPQQEITFAARDALSLAKLTIITVPDPPEDP EVLNKTKESITLSWFTPLHDGGSPILGYRVELRLVDSALWLPCQPEPVCNTEFLVENLIP ESGYRFRVAAINIAGTGDSVELPQTVQLEAPTPPPTTPDTEVKQEEAEALGQPNLPPEAA EEGDVHELWEASAKKRRMSREPTLDSITEQPEEDGKGGKKKSDQKDLESSKKVETTSVEK EQAIVSKKETESNLVTSSEDQSLSGGATLVSYLKTSSTSSVTAVNEGHTMTTERFFAHFQ MSDQKTVQQTEVKTTTVHQTDNKQVTTEETDIMEISKEDEPELREAAIKIQAAFKGYKAR KDMRPVFKDVFKDQTKEPNGTIHLECVAEGKPEKVRWLKDGEPLTDGKHHHIDIYNDGTC SLVITAITTKDTGVYTCEVTNKYGVNSHSGKVTVGTVRESSGRRPLTVGYSADSEPESSS GSEMDESLRKASRRLRRLLRTCLPPDVEEEPFVSADEGDLRAPDPQSYREDDNYIYIRFD SRTEAEVASKRFQEMFTIHGVPVETNIQDAGPLRVELRIKKAGYIQDGTQTPTQDRQPPA FMAGAQAAPVFLTELQTQDVPDGYPVSFDCVVIGKPPPTVRWFKDGKVLEENDHYMINED LEGCHQLIITTVLPTDMGVYRCTAENSSGLAATKAELRVDMSCSSDYDTAADATETSSYV SAKGYMSRETETFESVAEDDQLPQVVEELHDVRVCPGSPIAKMQLKVKGFPKPRLYWFKD GHPLRPSNRILLRTDRDIHGLEILEVKKDDMGEYSVYITNSAGSAYSSARLMVLGPGEMM PLDKKDSKEPLVPPRFLERFSNRKVKQGASITLSVKVEGSPTPMVSWLKEESLEDVLWIK PDTKGYKIAGSGRQHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDETSQQKKEIK ASEVLGITISPPEGEASSGNEVKVPYLGEVGTEEFLMKLTTQITEMVSAKITQDSLQNHE VLQWMKSWPKNTTSLRVPGGDSDDETKTPSPSPHHGRSRPPSLIADSSSESDEGDARGEM FDIYVATADYNPTIASKESISLKEGQYVEVLDSAHPLKWLVRTKPTKMTPSRQGWVSPAY LDKKLKLSADAGDLPETSAEEVSEGEYKRKLFQLIQEMINGESEFVKEVDFFTSHHMKHA DIPDAPPDVNSQKETIFRNIDDIKSFHGRAFLPTLNDCETDDDVAMCFLRSKAGFEQYLQ YLVGQPQAESAVSDKAVHRFFKEYSEKEQAGADPAGPPVRSINAYLQQPLERIQKYKVFL KELIRNKARNGQNCCLLEEAYAMVSALPQRSENTHHVTMIQNYPATLEVLGEPIRQGPFQ VWEGAPGIRSSSRGHHRHVFLFKNYCIICKPKRDSNADTQAYVFKNMMKLNNIDVNETVE GDDRAFEIWHEREDSVRKYTLQARTITIKNSWLRDLRELQQRYSMPAWSPPDFDEILGNC TAELGQTVKLACKVTGMPKPTVTWYKDGRAVEADPHHIIIEDPDGSCTLILDNMTADDSG QYMCFATSSAGNASTLGKITVQVPPRFVNKMRNAIFVAGEDAQFTCVIQSAPNPKIRWFK DSRLLTDQEKYQTYSELRSGVLVLIIKNLTERDLGHYDCELSNRLGSAKCAADLVLPSAL ARTGEQAITIEVTEQETKIPKKTIIIEETITTVVKNPRMRRHRSPGLTLTAAHRSETSTP EPAAARLRRVPTPRKTTIPTLYVTEPEGAEARAMESKPRWVEVEEVIEYKVNKSPRLPRR RGISPAVSDRAAASSRPKRSQLENPNTNNSNNTLVEQAQAELHGDVSIQPLSWEEVQGNA PSAEPHELSSVLSPAGDDSDDLDDQQTVIFEPEDDDDDLILSREQEPHILKSGDRVLTLE DLEDYVPEEGESYGSSNAPAEQPCEISVLQREIGGSAVGQPVLLNVGRPVVPRQRSSFFS RFKEHLPSSIFSSSSVPHASGTRPRTERRVPIQVSHAKLEVQPSYCSEVQRVEGGQQSFK TKVSTQTYGYTSVGNPVVLQIRDHHYPNQ NT seq 19890 nt NT seq  +upstreamnt  +downstreamnt atggatccaaacctgtatggaggcgtccccaggtttctgactcgcccaaaggcgttctcg gtgtgtgcaggcaaagatgccaccctcagctgcaccatcgtgggcagcccgaccccgctg atcacctgggagaaggacaagttgaagctgacgtctggggggcgcttcaagacagtggag gatggagacgtgtaccgcttgaccatctacgacttaacgctggaggatggcggacagttc atgtgccgggccaagaacagcgttggggaagcttatgctgcggtaaccgttaaagtggct ctgcctacagagatggctccgagggcccccgtgttcatgatgaagcccacctctgcacgg gtaggtttgggaggcgatgttgttttccactgccgggttgcagctcaccctgaggccaac tttgactgggaaaaggacgggcgctacctgggggagtcaaaccgcatcaagatcgtctct gacaccgatggcagcactttgaagatccaaagcctacgaaacctggacagcggcacctac acctgcagagccaagaacactgttggccgtgcacacgctgccgcagctctcgtcgtagat gcccaggattcccattatcagtccgcggataagaacacctccctcctctctcaccttcaa aagcgcaaagaggaaatgaataaggacatctccatctatcgcactgaggagaagagctcc tctgtttcttcctctaccacagatggtttcagctctctgagtctggagcatgcactgagg gcatctgcgctggcaacgctgccgaaaggtgtattcacccgaacctgcaccgtgactgag ggcaaacacgccaagcttagttgctttgtgacgggtcacccgaaaccccacattatctgg aggaaggatggaatgaacatcggtgaaggccgcaggcatgtcatttatgaggaccaggcc gagaacttcatcctgaaggtcctgtactgcaagcagactgataatggtctctacacctgc aatgcaaccaatatggccgggcagacctacagtgctgtgttggtgacagtcaaagagccc aaagtgccgttcaggaggaagttgcaggacatcgaggtccaggagaaaacatcggccaca ctgatgtgtgaggtgcctgttgttgccacccatgcccactggttcatggaggaaacgatg ctggaacaaaataccaaatatcgcatggaggaggagggcaccctgcgtcgtctcaccatt cacaatgtcaccaccaacgatgacggtgtttatatctgcgagatgaaggaaggcagtcgc acggtggccgagctcactgttctgggcaatattaccaagaagctcccccggcggacggtg gttcctgtcagcgatacggtcattttctgtgtcgagctggagcatccctacccggatgcc tactggacccgcaaaggggagaagctgaaggaagagtcccggatttccatagcctgtgtg ctgagacagtacacgctcaccattagagattgccaggctgaagactcaggtgaaatcgcc tttgtggctggagactgcaagacgtccactcgattcactgtcactgctgctaggaagcat ccccccgatcccccagtcaatgctgtggtgctgaacaagactgactcttccatcaccatt cagtggtctcctcctgacagcgatcgcccagtgcccattaagtgctacatcgtggagagg aggaaggttggcactcagacatggcagaggtgcaacgctggagaaaccattgtttccaca gagatcaccatctgcaacttcaaagaagagtccagcttccaattccgtatctctgccatg aatgactttggccagagcccccacctggaggtgcctggaagcttttaccttgaaccttct gcagagataaggaaaggcctgatggacaccactgcaaactctggcgaggagttctctatc accatcgagttgtctgctgtttgttctggttactggtacattaatggccgcgtcctgcgt agtggagctgactacctcatcaccaagtccaagaccacacacactctgctcttccgtgat atgaccatggaattgaatggagctgaagtcaagtttgttggtggaggctcacaaagcagt tgcatcttatctgtgaaagcccctcgtgttaggttcataaacaagtccgatctgacagag gtggtgacctgcactgcccaatccactgctcagctgactgctgaggtgtcggattatgaa acacaggtggtttggatgaagaacgggcgagaggtgaaaatgggcaagaagtatgaatat gtcatcattgaccgcaagaggatcctgatggtacacaatgttactgaagaggatgtgggc atctacgagtgtgttttagctgaggacaagatgtccctgcaactctctcttaaagatgaa cctgccaagttcctgaacaaggccagaggtgccatgggaatgtcatcgtcccttaaagga gatcttgagctgagctgcgaggtatctcctgccagcgctgtcgttgtgtggagaaaagat caggtggagatcactgaggaccaaagaactgccatggtctccaaagggactcaaaggaaa ctcgtcatcaagaacgccaagaaaagtgacgaaggacattactcctgtgagacggcagca gacaaagtcacattccaggtcaagataaaagaaactctagccgttgctgccttctccaac aaagagtcagtccagaaagaggtgaaggccactctctggcagaaagcaactcttagttgc aatgtgtcagatagcaaggcagaggtcaaatggtataaagatggcaagcagctaatatcc agccggaccatatactcagaagtaacaggcactgctcgtcagctggtatttgaaaaggtg gagaagagtgatgctggagaatatacctgtgaagctggcggggataagctggtcttcaag atatctgtttcagaggcccaggcagccttcttcaacaaagagtcagtccagaaggaggtg aaagctactctctcccagaaggctattttaagctgtgaggtagctgatagcaagacagag gtgaagtggtacaaggatgccaagctgctgacctcgagcaagacaatccatgcagagtcg aaaggccagagtcgccagctgtatatcgacagtgtggagaagaaggatgctggagagtac atctgtgaagccgggacagagaagcttgcttttaagattcaggtggaagagccgaagtca ttcttctccaacaaggagtctgttcaaaaggaggtgagagcgacgttctcccagaaaacc actctgagctgtgaggtttctgattccaagacagaggtgaagtggtacaaggacggcaag ctgctgacttctagcaagactattcatactgagtctaagggcaaaagtcgaatgctggtg atcgacagcgctgagaagaaggatgctggagagtacatgtgtgaagtcgggacagagaag cttgcttttaagattcaggtggaagagccgaagtcattcttctccaacaaggagtctgtt cagaaggaggtgaaagcgacgttctcccagaaaaccactctgagctgtgaggtttctgat tccaagacagaggtgaagtggtacaaggacggcaagctgctgacttctagcaagactatt catactgagtctaagggcaaaagtcgcacgctggtgatcgacagcgctgagaagaaggat gctggagagtacatgtgtgaggctgggactgagaagttggttttcaaactccaggcttca gacacacagattcaatctgcattctctaacaaagactcagtccagaaggaggtgaaagcc actgtctcacagaaagccattttaagctgtgaggtagctgatacgaagacagaagtgaaa tggtacaaggatggaaagctcctcacttcaagcaagaccattaatgcagtgtcaaagggc aagagtcgccagctggtgatcgacagcgtggagaagaaggatgctggagaatacatctgt gaggctgggactgagaagttggcctttaagatgcaggtggcagttacttctacaaaaatc ggggctaaatctggttccctcaacaatgaggctgtccagaaggaggtgaaatccaccctt ctcgagccaggcaatctgagctgggaagtagttgataacaccacagaggtgaaatggtac aaagatggcaaactggtgagtcccagcggtccagttgccttggaatcaaagggaaagatt catcaactggtggtggatagtgtagaggagaaaaatgcggaggagcacatctgtgaggtc cgaacagaaagtttggcatttaaagaacagttcacagagattctagccaaatcggccttc tccaaaaaggactcagtccaaaaggaggtgaaagccactcttacacagaaaaccatttta agctgtgaggtagctgataccaagacagaggtgaaatggttcagggatggcaagctgctg acctccagcaaaacagttcatgcagagtcaaaaggcctgagtcgccagctggtgattgac agcgtggagaagaaggatgctggagagtacatctgtgaggctgggacagaaaagctggcc tttaagattcaggttgcagaagccccggctggcttctcaaacaaggagtctgtccagaac gaggtgaaagttactctctcccagaaagccactttgagctgtgaggtttctgattccaag acagaagtgaagtggtacaaggacggcaagctgctgacttccagcaaagcagttcacatg gagtcaaagggaaagagtcgtgagctggtgattgaaaaaatagagaaaaaagatgctgga gaatacacctgtgagactggaacagagaagctggtatttaggctgcatgtgacagaagaa gctgtcaagttccagaagaagtctgtcaaagacacatgtattgttcaagcaagtgaaaac attgttttgaccactgagctgacctcggagagtggaagtgtgaagtggttgagagacggt gtggagatcaaagagggcagaaagtatgaaatgaaaaaagatggacattgtcgtaccttg atagtaaattccaccgaaactaaagacagtggaacgtactcctgtcaaactgctcatgac aaacaggagttcaaagttcaggtcaaagagtcagctttgaagtttgttgtccccctgaag tctgccgatgtggagttgggtgggacacttagtctgatgtgtgagctcaatcaagcctca ggcgatgttgtctggcaccatattggtcgtgagattaaacctggaggaaggcactgtgtc aggacagatggtgctaagcgggtcctcactgtgactgacatgacgaaggaagatgaagga gaatacagctgtgaatgtcgaaatgacaagacctctgccaaaatctcctctaaggagccc agagtagtgaggctgactactaaactcaacaatgtggctgcaatggagggaaaagacgcc atcttcaagtgcgctgccactccagcagacatcaacgtcaagtggttccacaacagcata cccatcacggccgggccaaagtataagatagagcacggtggcaacactcactcactcacc ataacctctgtcacccaaaaagatgctggagagattagcgttgatgcagaagggaaaagc tgcaaagctactttacaagtgcaacatgaacctgtaacctttaagaaaaagctggaaaac ctgacagtggatgagcagagtgaagtgaagatggaggtggagctcagtaagaaatcggat gaagtcaggtggatgaagaacagcatcgtgttgcaggctgcaggaaacctggagattcgg gtcgatggagccaagcaggctctggtctttaagagcgtgactcacggtgatcgtggcatc tactcctgtgaaactctggatgacaagacccaggccaagctcacagtagaaatgaagaag atcaaggtaataaagggccttccagaaaccaaggcacatgagacagagacagtgacccta gaggtagagctcagtcaggctgatgttgaaggctcctggaccagggatggggccaagtta aagccaggggccaactgtcgtatcacagcactgggaaagaagcacgctcttacgctgtcc aatcttaagagagatgatgctggaactatttccttccaagctgatggtgtccatacttca ggcaaactgattgtcacagaaccgcctgctatggtctccacacccattatcgatatgagt gttcctgagaaggagaaagttacttttgaatgtgaagtgtccagaacaaatgctgatgtt aaatggtttaaggataatgtggaactgaaaccagggaaaaactatggcatccattcgttg ggcagaaagcgcactttggtcatcagcaaatgcacccctgcagatgcaggcagttacgtc tgtcgcaccactgatgataacacctctgccaagctcatcgttcatgccagagatatcaag ataattaagaaactcgaggatgtggaggtgatggagaaggagagtgctgcatttgtctgt gaaatctcacatgatgaggtggactgtcagtggtacaaaggaagtactaaagtcaaagtc agtgacaacatcaagatgagacaagagggcagaacctatgtactgctgtttaagtcggtt tccccagaggatatgggtgatatcaaatttacagctgagaagacctcttcatctgcaaaa ctcaaagtgaaagagctgcccgtcaagtttgtgaagagactcagggataagatagcgatg tttaagcatcgtggttatctcgaatgccaagtgtcacgtgccagtgcaaaggtgaagtgg tacaagaacaagacggaaatcaaacccagcaagaagcacgagatcagaagtgaagatgtc taccgaaaactcaccatcaatgatgtggacactggggacgaagacacatatacctgcgac gccactgacgaccagacgtcctgtaaactgcttgtagaagagcagtccatcagcattgtg cgggagcttagttcagtagaagtgacagagcctttcgcagctgtctttgaagttgaaatc agtatggaactggtgaaacctcccatatggactctgaatggagttgctgtgcaggagagt gcagatgctgaaatggagaaagaaggcacgctgcaccgtctcactttcaaaaagacaaaa gcctcaatgacaggacctgtgcagtttacagctgggaagagcaaatctcttgctcaactc acagtaaaagagcgtccacttgagattgcagagcccattaaagatgtcaaggcgaaggag aaaagctctgccctgttctgctgcaaattctccacggcagccaaagaggtgaattggttt aaaggtcaggtacttctggcggcatcagacaagtacaacatgaagaaagacggcacaagg gctcaacttactattcaagggctaactggagaagacggcggagagtaccgctgtcagtcc ggacctgctgagaccaaaggcacactcactgtcgaagtgcgggaaattaagatcaccaag cacttgatcgacacagaggttgatgaagacagtgatgcagtgttcacgtgtgagattaac tatgcagatgaagaggcacagtggcttctgaaagacaaggtgcttctcactaatgaagtc aacaccatctctcatgaggggaaggttcacaagctcatgctgaagaacatggctcctcag gacggggggaccatcacctttcaagtacgcaaggtgaaagagtctgttacactcaaagtg aaagagaagcttgctgtgttcctcaagtctctcgatgatgtcatcggagaggagaaaggc atgataactctgacgtgtgaggcgtccaagcccagggtttcacctatatggagaaaagaa ggtaaagtcttgaaggctggacccaagtatgagctcctccacacaggcaagtctttgggc ctgatcatcaaggacgccaccaaagacgatgctggagattacagttgtgatctgggaaca gaggtttccaaggcaaaggtcactgtcagagagattggcattggaattaccaaatggctg aagtctgctgaggtaaacgagggggagacatgcagctttgagtgcatcttatctcgtgag aacacagatgagtgctcgtggtctctgaatggcaaagccatttcaaacggaggccgtttc aatgtcaccaataaaggccgcaagtacatgttaaacatcaaggatgtcacccctgctgat gctggtgaggtggtcttcaacattaaagacttgagcactaaaacaacattaacagttgaa ggcagagcttcatctgtgtccaaaggactgcagaatgctagcgctgttcaaggggaagat gctgtgttttcctgtgaggtgacacaggctagttccactgtaaagtgggccaaggaaggc aaagccatcaagaagagccagaagtacgacatcagccaagaggataaggtcatgaagctc accatccatagtgtctctgcccaagactcaggagagtacagctgtgaagtcgttggaggt gcaaccaccaaagcccaactggaaattaaggagccgatccataaattcactgaagtgctg aaggacagccaggcagacgagaagagctctgtgaccttgcagtgtgagacagctcaaagc ccatccacggttatctggcttaaagggcacacagagctcaaggcaggaggtcgatatgag atgtcccagaaagagcgggtcttaactctcaccatcaaacagctggaggagaaagacaca gatatctacacctgtgatgtgatcactgctaagaacatggcaaaggtcacagtcaaagcc ctgcctgccacctttaaagaaaaactcaagaaccaagataaaaaagaaggggagactgtg acactttgttgcgagttatcaaaacctgcgaccgacattcagtggaagaaaggctctgaa attctcaaagctggagagaagtatgagatgaagcagaagcacaccgctctggaacttcaa atcaaagatttaaaggttgaagatagtggagagtactcttgtgtgtgtgtggaccagaag acatctgcatctgtgaaagtcaatgcattaccaccgaccttcatacagaagctgaagact caggaagctgaggagggagtagatattactctgaactgtgagctctccaaacctggagtc tcagtggagtggaagaagggaactcaggtcctgaagtctggagagaagtaccagatgaag cagaaagcctctgtgaatgaactgctcatcaacaaagtggtgccagaagacagtggagac tacagctgtgtgtgtggagaccagacgaccacagccagtctcaagatcaaggcccaacca gtgaccttcaaacagaagttagagactcaagaagcagaggagggagccagcgtcactctg cactgtgagctctccaaacctggagtctcagttgagtggaagaagggaactcaggtgctg aagtctggagagaagtaccagatgaagcagaaagcctctgtgaatgaactgctcatcaac aaagtggttccagaagacactggagactacagctgtgtgtgtggagaccagaagaccaca gctagtgtcaagatcaatgcccaaccagtgaccttcaaacagaagttagagactcaagaa gcagaggagggagccagcgtcactctgcgttgtgagctctccaaacctggagtctcagtg gagtggaagaagggaactcaggtcctgaagtctggagagaagtaccagatgaagcagaaa gcctctgtgaatgaactgctcatcaacaaagtggttccagaagacactggagactacagc tgtgtgtgtggagaccagaagaccacagctagtgtcaagatcaatgcccaaccagtgacc ttcaaacagaagctagaaactcaggaagctgaggagggagccagcgtcactctgcactgt gagctctccaaacctggagtctcagtggagtggaagaagggaactcaggtcctgaagtct ggagagaagtaccagatgaagcagaaagcctctgtgaatgaactgctcatcaacaaagtg gttccagaagacactggagactacagctgtgtgtgtggagaccagacgaccacagccagt ctcaagatcaaggcccaaccagtgaccttcaaacagaagttggagactcaggaagcggag gagggagccagcgtcactctgcactgtgagctctccaaacctggaatctcagttgagtgg aagaagggaactcaggtcctgaagtctggagagaagtaccagatgaagcagaaagcctct gtgaatgaactactcatcaacacagtggtgccagaagacagtggagactacagctgtgtg tgtggagaccagaagaccacagccagtctcaagatcaaggcccaaccagtgaccttcaaa cagaagctagagactcaagaagcagaggagggagccagcgtcactctgcactgtgagctc tccaaacctggagtctcagttgagtggaagaagggaactcaggtcctgaagtctggagag aagtaccagatgaagcagaaagcctctgtgaatgaactgctcatcaacaaagtggttcca gaagacactggagactacagctgtgtgtgtggagaccagacaaccacagctagtctcaag atcaaggcccaaccagtgaccttcaaacagaagttagagactcaagaagaggaggaggga gccagtgtcactctgcattgtgagctctccaaacctggagtctcagtggagtggaagaag ggaactcaggtcctgaagtctggagagaagtaccagatgaagcagaaagcctctgtgaat gaactgctcatcaacaaagtggttccagaagacagtggagactacagctgtgtgtgtgga gaccagaagaccacagctagtctcaagatcaacgcccagcctgtctttttcaaaactcag ctgcagaaggttgaaagacaggcaggggagatcgctattcttcgctgcgagaccacaaaa cccggtgcaattgttgtctggaggcacggtgacagagagctggcatccagcagcaagtac cacctgaaacaggaagggactgtagtcgagcttgtcatctataaactgcaaggagctgac tctggagaatattcctgtgatacaggcagtcgaaggacgtcagctgtcctcactgtgcat gaggtcgagattaccatactgaaattcttggagagctcagttgtctatgagggggaagat gtccactttgagtgtctgctctctcatgacgaggctcctctggcccagtggaaactccag gacgtcccactacagaataatgaaatgaacctgatcaagactgagaaccgagtgcacagc ctcacactcagaggtgtcaccacaaccgactcaggaacagttactttcactgtgggaaac cacacttcaacggcttctctcacagtcagagcagctgctccagtgttattcaagaaggag ctggaaagtcaagaggccacagaaggaggcaaagtcaccctgtcctgcgaaacatccagc cctgattgcaaggtaacctggcacaagggctcgtctgaactcacccacggggagaagtac accatcgtgcagggaggaaccactcacaccctggttatacacaagctgaaagtggaggat agtggagaatacaccagccaagcaggggacaagaagagcactgctaccctgactgtgaaa gagcgtgtgcgcatcatccgagaactctacgatatcactgtcaccactgggcaggatgca gtctttgaagttgagctgtcacactcgggcgtgacaaacggggaatggtggctcgcggac aacctcctccagaataatgatttgaatcaaatgagcagccagggcagagtacatcgtttg accctgaagatggtaaccacggaggaatcaggagatgttgccttcgtagtgggagaagag aaaactgtggcctgtctgctggtggaggagaaacccaaagtgaaaatcgtagagaagccg cacaacactttggtaatcgagggtgaaactgtcactctggcctgcaccatctctgacccc aaggccacagtcacctggatcagaaacaacgtggccatccaagctggtctcaagtatgac ctgaagaagaatggagctttccatcagctttgtatcctcaacgggttgcctgaggactca ggagtgtacacgtgtgacactggagatgtacaatgtgaggtcacggtgacggtggaaggt gccccggtattcttccggaaagagcttaagaacgaggatgccgtagagggtgatgattct accctgcgctgtgagctatctaagccaggtgtttgtgttgagtggaggaaaggaggcatt gtcctcgagcccggtaagaagtataagatgaggcaggaagggtgcattcgagagctctgt ataagtaactcggatcctgaagacagtggctactacacctgtgacgcaggagaccagctc actacggcttctttggcagtgcaagtgaaagaagtcttcattgtttgtggtcttaagacc accgacgtctttgttggggaatgggcaaccttctcctgccagctgtctgctatcgcacca ggcaaggtgcagtggtggctggatggcaccttgttggaaaacagcccttttagtgagata gggctgagccagggccacatctacacactgaccttaaagagcctggccacagacgactct ggcactgtcacgttcaaagctggcagtttaacatcaagctccaagctcttagtcaaagat cccacggttgaagtggtgagcgagatgcaggacctttgtgtggtcgaaaaccaaccggct gagttcatctgccagtattcacggccggtcagggctcagtggaagaaagacgggcagcca ttgcagcctgatggccgaagggtgttggtggagcaggactggaatgtggctcgcttgtac attagcagtgtgtccactggggacaagggcacatactcctgtgaggcagaggggaccagt gtggtagcttcacttcatgtggaagggaaaccaataactattgttcagggcctggagaat gcagaaaccttcgatggaggggaaacactattcgagtgtgccctgtctcgccccgagaac aaagactgccactggtttctcgatggcaaaccagtgaaggaatctcgtaatgttgagatt gtgtcatttgagagtggccgtcgtcacctgctcctgctgaaggagttgcacgttaaagac agttgcacagtgatgttcaaagctgggacatcatccacatctgcacagctctctgtcaag ggatggcagctggatgttgtgaagggtctggaagacaaagtcgctgccgtaggagagaag gttgaattttgtgtcgagctgactgaacccatccccgtggcagaagtagcctggtatgct aacggggttgagctcaagcccagcgatctctgggctatgagggctgacggctgctcctat cgccttgtcttgagacgtgcaccacttctgccccagcaggaaataacatttgctgctaga gatgctctctctttggccaagctcactatcatcacggtacccgatcccccagaggacccg gaagtcctcaataagaccaaagagtctataaccctctcttggttcactccgctacatgat ggagggagtcctattcttggctacagagtggagttgcgactggtagacagcgccctctgg ctgccgtgtcagcccgaacctgtgtgtaacacagagtttttggttgagaatcttatcccc gagagtggctacaggtttagagtggcagccatcaacatagctgggactggagattctgtc gagctgcctcagacggtgcagctggaggcacctacaccaccaccaactactccagataca gaggtaaaacaggaagaggcagaggccctggggcagcccaatctgcctccagaggctgct gaggaaggtgatgtccatgagctgtgggaggcttcggctaagaaacgtcgcatgagtcga gagcctactttggactccatcactgaacaacctgaagaggatggtaaaggtggtaaaaag aaatctgaccagaaggatctagagtcctcaaagaaagtggaaacaacatctgtagagaag gagcaggccattgtgtctaagaaggagacagagtccaacttggtcaccagctctgaggat caatctctttcagggggtgcaacacttgtgtcctacctcaagacgagcagcacatcttct gtcacagccgtcaatgaaggacatacaatgaccactgagaggttctttgcacatttccag atgtcagatcagaaaacagtgcagcaaactgaagtgaaaacaaccacagttcatcagaca gataataaacaggtgactacagaggagacagacatcatggagatcagtaaagaggatgag cctgagctcagagaagctgccatcaaaattcaagctgccttcaaggggtacaaggcccgt aaggacatgcgtcctgtcttcaaagatgttttcaaagatcagaccaaagaaccaaatggc accatccatctggaatgtgtggcggaaggtaaacctgaaaaggtgcgttggctgaaggat ggtgaaccactaacggatggcaagcaccaccatattgatatctataacgacggcacttgc tcactggtcatcactgccatcaccacaaaggatacgggagtttacacttgtgaagtcacc aacaagtatggagtcaactctcatagcggtaaggtcacagtagggacagtgagagaatcc tctgggagacgcccactgacggtgggctacagtgcggacagtgagcctgagagctcctcg ggcagtgagatggacgagtcactgaggaaggcaagcagacgtctccgccgcctgttgcgc acatgtctcccacccgatgttgaggaagaaccatttgtcagtgcagatgagggagacctg cgagccccagatcctcagtcttaccgtgaggatgataattacatctacattcgctttgat tcacggacagaggctgaggtcgcctctaagaggttccaggagatgtttactatccacggg gttcctgtagagacaaacatccaggatgcggggcctcttagagtggagttgagaatcaaa aaggctggctacatccaagatggcacacagacccccacacaagacagacaacctcctgca ttcatggctggagcccaggctgccccagtttttctgacagagctacaaacccaggacgtt ccagatggttatccagtcagctttgactgtgttgtgattggcaaacctccaccaactgtt cgctggttcaaagatggcaaagtgctagaggaaaatgaccattacatgataaatgaagat cttgagggctgccaccaactcatcatcaccactgtactgcccactgatatgggtgtctat cgctgcacagctgaaaacagcagcggcctcgcagccactaaagccgaactcagggttgac atgtcttgcagctcagattatgacactgctgctgatgccactgagacgtcttcatatgtc agtgccaaaggctacatgtccagggaaactgagacctttgagtctgtggctgaagatgat cagttaccacaagttgtggaggagcttcatgatgtccgtgtttgtccaggttcacctatt gctaaaatgcaacttaaagtaaaaggcttcccaaaacccagattgtactggttcaaagat ggccaccctctgcggccctcaaataggatcctgttacgaacagacagagatattcacgga ctggagattctggaggtgaagaaagacgatatgggggagtactcggtttacatcactaat tcagcgggttctgcttactcttccgctagactgatggttctgggtccaggggagatgatg ccactagataagaaagactccaaagaacctctggtgccaccacgcttccttgaaaggttc agcaacaggaaggtgaaacaaggagcgagcattacgctgtctgtcaaagtagaagggtct cccacgcccatggtctcctggctaaaggaggagtcattggaggatgtcctgtggattaag cctgataccaaggggtataaaatagcaggctctggacgccagcacagcctcatcctgatg gacgttggcacagagtacactggcgcctacacctgtatcgctacgaacagagcaggacag tccatctgcacggcccacctcgaggtggatgagacatcacaacaaaagaaagagattaaa gcctcagaggttcttggtattacaatcagtcctccagagggagaggctagcagtggaaac gaggtaaaagtaccatacctaggtgaagtaggaacagaggaattccttatgaaactcacc acccagatcactgaaatggtatcagccaagataactcaagacagcttacagaatcacgaa gtgctccagtggatgaaatcttggcccaaaaataccacttcattacgtgtacctggcggt gacagtgacgatgagaccaagactccatctccgtcacctcatcacggtcgctctcgtcct ccctcactcatcgctgactcctcctcggagtcggatgagggcgacgccagaggggagatg tttgatatctacgtggcaacagcggactataaccccaccatagcaagcaaagaatcgatc tctctgaaggaaggacagtacgttgaggttctggactcggctcatccactcaaatggttg gtccgaaccaaaccgaccaaaatgacaccatcccgccaaggctgggtctcacctgcctac ttggacaagaaactaaaactctcagctgatgcgggtgaccttccagagacaagtgcagag gaggtttctgagggtgaatacaagaggaaattattccaactgatccaggagatgataaat ggagaatcagagtttgtaaaggaggtcgacttctttacctcccatcacatgaagcacgca gacatccctgatgcacctcctgacgtcaacagccaaaaggaaacaatattcaggaacatt gatgatatcaagtccttccacggcagggcgttcctcccgacgctgaacgactgtgagaca gatgatgatgttgccatgtgcttcctgaggagtaaggcgggctttgagcagtacctccag tatcttgttggtcagcctcaggcagaatcagcagtcagtgacaaggctgtccaccgcttc ttcaaggagtacagtgagaaagagcaggctggtgcagaccctgcaggtccccctgtacgc agcatcaacgcctacctgcaacaacctctggagaggattcagaagtacaaggttttcctc aaggagctcattcgaaacaaggcgagaaatggtcagaactgctgcctcctggaagaagcg tacgcgatggtgtctgctctccctcagcgctctgagaacacccaccatgtcaccatgatc cagaactatcccgccacactggaagtacttggagagccaattagacagggaccatttcaa gtgtgggagggagctcctggaattaggtcgtcctctagaggtcaccaccggcacgtgttc ctctttaagaactactgtataatctgcaaacccaagagagacagcaacgctgatacacaa gcatatgtctttaagaacatgatgaagctgaacaacattgatgtgaatgagacagtggag ggtgatgacagggcctttgagatttggcatgaacgggaggactcagtgaggaagtacact ttgcaggccagaactatcaccatcaagaactcatggctgagagacctcagggaactgcag cagcgatacagcatgcctgcatggagtccccctgactttgatgaaattcttggaaactgc acagctgagctgggacagactgtgaagctggcctgcaaagtcactggaatgcccaaacct acagtcacctggtacaaggatggacgtgcagtggaggcagatcctcatcacatcatcatc gaggaccctgatggttcctgcacactgatcctggacaacatgacagctgatgattctggc cagtacatgtgctttgccacgagctcagctggcaatgccagcactcttggaaagatcacg gttcaggtacctcctcgttttgtgaataaaatgaggaacgctatctttgtcgctggtgag gacgcgcagttcacctgtgtcatacagagcgcccccaaccccaagatcaggtggttcaaa gacagccgcctgctgactgaccaggaaaagtaccagacctacagtgagctccgtagtgga gtgctggttctgataataaagaacctgacagagagagacttgggacactacgactgtgag ctgtccaatcgactgggcagtgccaagtgtgcagcagatttagttcttccctctgctctg gcccgaactggtgaacaggccatcactattgaagtcactgagcaggaaaccaaaatacca aagaaaaccatcatcatcgaggagactataaccaccgtggtgaagaaccctcgtatgagg aggcacaggtcccccggcttgactcttactgcagcccaccgctctgaaacctccacccca gagcccgctgcagccaggctgaggagggtgcctactccaagaaagaccactatccctacc ctctacgtcactgagcccgagggcgctgaggccagagccatggagagcaaacccaggtgg gttgaggtagaggaggtcatcgagtacaaggtcaataaatctcccaggctgcccaggagg agaggcatctcacctgcagtctctgatcgggcagccgcttcctccagacccaaaaggtct caactggaaaacccaaacaccaacaactccaataacacgctggtggagcaggcgcaggcc gagctgcacggagacgtcagcatccagccgctctcctgggaggaggtgcagggcaacgct ccctctgcggagccacatgagctctcatccgtcctcagtccagctggagacgacagcgac gacctggacgatcagcaaactgtcatctttgagcctgaagatgacgatgacgacctcatt ctatccagagagcaggagcctcacatcctgaaatcaggcgatcgtgtgttgaccctagag gacttggaggactacgttccagaggaaggagagtcctacggctcctccaacgctcctgcc gaacagccttgtgagatctctgtgctgcagagggagatcggtggctccgctgtggggcag ccggtgctcctcaacgtgggccggcccgttgtgccgaggcagaggagcagcttcttcagt cgcttcaaggagcatctccccagcagcattttctcctcctcctccgtccctcatgccagc ggaacgaggcccaggaccgagaggcgcgtccccatccaagtgagccacgcaaagctggag gtgcagccttcctactgctcggaggtgcagagggtcgagggcgggcagcagagctttaaa accaaagtatcaactcagacgtacggatacacatcagtgggaaacccagtcgttcttcaa attagagatcaccattatccaaaccagtag

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