KEGG   PATHWAY: ppor02030
Entry
ppor02030                   Pathway                                
Name
Bacterial chemotaxis - Pseudodesulfovibrio portus
Description
Chemotaxis is the process by which cells sense chemical gradients in their environment and then move towards more favorable conditions. In chemotaxis, events at the receptors control autophosphorylation of the CheA histidine kinase, and the phosphohistidine is the substrate for the response regulator CheY, which catalyzes the transfer of the phosphoryl group to a conserved aspartate. The resulting CheY-P can interact with the switch mechanism in the motor. This interaction causes a change in behavior, such as in direction or speed of rotation of flagella.
Class
Cellular Processes; Cell motility
Pathway map
ppor02030  Bacterial chemotaxis
ppor02030

Other DBs
GO: 0006935
Organism
Pseudodesulfovibrio portus [GN:ppor]
Gene
JCM14722_00320  cheA-1; chemotaxis protein CheA [KO:K03407] [EC:2.7.13.3]
JCM14722_00330  cheB2_1; chemotaxis response regulator protein-glutamate methylesterase of group 2 operon [KO:K03412] [EC:3.1.1.61 3.5.1.44]
JCM14722_01100  cheW-2; chemotaxis protein CheW [KO:K03408]
JCM14722_01310  [KO:K03414]
JCM14722_01550  cheW34H-1; chemotaxis protein CheW [KO:K03408]
JCM14722_01720  pomA; flagellar motor protein MotP [KO:K02556]
JCM14722_01730  pomB_1; chemotaxis protein [KO:K02557]
JCM14722_01740  pomB_2; chemotaxis protein [KO:K02557]
JCM14722_01750  cheX; chemotaxis protein CheX [KO:K03409]
JCM14722_02630  fliM; flagellar motor switch protein FliM [KO:K02416]
JCM14722_03500  motA; chemotaxis protein MotA [KO:K02556]
JCM14722_03510  [KO:K02557]
JCM14722_04120  cheY-3; response regulator [KO:K03413]
JCM14722_04260  cheY34H-2_1; response regulator [KO:K03413]
JCM14722_06670  cheV-3; chemotaxis protein CheV [KO:K03415]
JCM14722_07120  [KO:K03413]
JCM14722_07330  [KO:K03406]
JCM14722_07530  [KO:K03406]
JCM14722_08100  mcp40H-11; chemotaxis protein [KO:K03406]
JCM14722_08240  fliG; flagellar motor switch protein FliG [KO:K02410]
JCM14722_08530  [KO:K03406]
JCM14722_10180  [KO:K03406]
JCM14722_10610  [KO:K03406]
JCM14722_11140  [KO:K03406]
JCM14722_13660  dcrA; chemoreceptor protein A [KO:K03406]
JCM14722_16190  [KO:K03406]
JCM14722_16750  cheY; response regulator [KO:K03413]
JCM14722_17650  cheR-2_1; chemotaxis protein methyltransferase [KO:K00575] [EC:2.1.1.80]
JCM14722_18600  [KO:K03406]
JCM14722_19800  mcp34H-12; chemotaxis protein [KO:K03406]
JCM14722_20000  cheD2; putative chemoreceptor glutamine deamidase CheD 2 [KO:K03411] [EC:3.5.1.44]
JCM14722_20710  [KO:K03411] [EC:3.5.1.44]
JCM14722_21120  cheR-1; chemotaxis protein methyltransferase [KO:K00575] [EC:2.1.1.80]
JCM14722_21660  fliN; flagellar motor switch protein FliN [KO:K02417]
JCM14722_21680  [KO:K02557]
JCM14722_21690  [KO:K02557]
JCM14722_21700  motA-1; chemotaxis protein MotA [KO:K02556]
JCM14722_22130  [KO:K03409]
JCM14722_23290  cheV-1_1; chemotaxis protein CheV [KO:K03415]
JCM14722_24520  cheV-1_2; chemotaxis protein CheV [KO:K03415]
JCM14722_28020  [KO:K03407] [EC:2.7.13.3]
JCM14722_28040  cheY34H-2_2; response regulator [KO:K03413]
JCM14722_28200  cheV-1_3; chemotaxis protein CheV [KO:K03415]
JCM14722_31060  motA-2; chemotaxis protein MotA [KO:K02556]
JCM14722_31070  [KO:K02557]
JCM14722_31560  cheB2_2; chemotaxis response regulator protein-glutamate methylesterase of group 2 operon [KO:K03412] [EC:3.1.1.61 3.5.1.44]
JCM14722_31580  cheR-2_2; chemotaxis protein methyltransferase [KO:K00575] [EC:2.1.1.80]
JCM14722_31590  cheY-2; response regulator [KO:K03413]
JCM14722_31600  [KO:K03407] [EC:2.7.13.3]
Compound
C00049  L-Aspartate
C00107  Dipeptide
C00121  D-Ribose
C00124  D-Galactose
C00208  Maltose
C00716  Serine
Reference
  Authors
Kristich CJ, Ordal GW.
  Title
Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis.
  Journal
J Biol Chem 277:25356-62 (2002)
DOI:10.1074/jbc.M201334200
Reference
  Authors
Kirby JR, Kristich CJ, Saulmon MM, Zimmer MA, Garrity LF, Zhulin IB, Ordal GW.
  Title
CheC is related to the family of flagellar switch proteins and acts independently from CheD to control chemotaxis in Bacillus subtilis.
  Journal
Mol Microbiol 42:573-85 (2001)
DOI:10.1046/j.1365-2958.2001.02581.x
Reference
  Authors
Szurmant H, Bunn MW, Cannistraro VJ, Ordal GW.
  Title
Bacillus subtilis hydrolyzes CheY-P at the location of its action, the flagellar switch.
  Journal
J Biol Chem 278:48611-6 (2003)
DOI:10.1074/jbc.M306180200
Reference
  Authors
Szurmant H, Muff TJ, Ordal GW.
  Title
Bacillus subtilis CheC and FliY are members of a novel class of CheY-P-hydrolyzing proteins in the chemotactic signal transduction cascade.
  Journal
J Biol Chem 279:21787-92 (2004)
DOI:10.1074/jbc.M311497200
Reference
  Authors
Yoshihara S, Geng X, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M.
  Title
Mutational analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803.
  Journal
Plant Cell Physiol 42:63-73 (2001)
DOI:10.1093/pcp/pce007
Reference
PMID:8104179
  Authors
Darzins A.
  Title
The pilG gene product, required for Pseudomonas aeruginosa pilus production and twitching motility, is homologous to the enteric, single-domain response regulator CheY.
  Journal
J Bacteriol 175:5934-44 (1993)
DOI:10.1128/JB.175.18.5934-5944.1993
Reference
  Authors
Szurmant H, Ordal GW
  Title
Diversity in chemotaxis mechanisms among the bacteria and archaea.
  Journal
Microbiol Mol Biol Rev 68:301-19 (2004)
DOI:10.1128/MMBR.68.2.301-319.2004
Reference
  Authors
Rao CV, Glekas GD, Ordal GW
  Title
The three adaptation systems of Bacillus subtilis chemotaxis.
  Journal
Trends Microbiol 16:480-7 (2008)
DOI:10.1016/j.tim.2008.07.003
Reference
  Authors
Muff TJ, Ordal GW
  Title
The diverse CheC-type phosphatases: chemotaxis and beyond.
  Journal
Mol Microbiol 70:1054-61 (2008)
DOI:10.1111/j.1365-2958.2008.06482.x
Reference
  Authors
Miller LD, Russell MH, Alexandre G
  Title
Diversity in bacterial chemotactic responses and niche adaptation.
  Journal
Adv Appl Microbiol 66:53-75 (2009)
DOI:10.1016/S0065-2164(08)00803-4
Related
pathway
ppor02040  Flagellar assembly
KO pathway
ko02030   

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