KEGG   Pimephales promelas (fathead minnow): 120462011
Entry
120462011         CDS       T08155                                 
Symbol
plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
pprm  Pimephales promelas (fathead minnow)
Pathway
pprm00562  Inositol phosphate metabolism
pprm01100  Metabolic pathways
pprm04012  ErbB signaling pathway
pprm04020  Calcium signaling pathway
pprm04070  Phosphatidylinositol signaling system
pprm04370  VEGF signaling pathway
pprm04625  C-type lectin receptor signaling pathway
Module
pprm_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pprm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120462011 (plcg2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    120462011 (plcg2)
   04370 VEGF signaling pathway
    120462011 (plcg2)
   04020 Calcium signaling pathway
    120462011 (plcg2)
   04070 Phosphatidylinositol signaling system
    120462011 (plcg2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    120462011 (plcg2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pprm04131]
    120462011 (plcg2)
Enzymes [BR:pprm01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120462011 (plcg2)
Membrane trafficking [BR:pprm04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120462011 (plcg2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120462011 (plcg2)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 PH SH3_9 EF-hand_PLCG1 PH_12 SH3_2 PH_14
Other DBs
NCBI-GeneID: 120462011
NCBI-ProteinID: XP_039506342
LinkDB
Position
Unknown
AA seq 1251 aa
MAGRTQQGDLTEYKKSLIKRDLEMGIVMTVYRQRMERLTVQVIMETRQVAWTRTADKTEG
VLDLFEIREVRPGKNSKEFDRFKDTKDKNSDPNTCFTIFYGSQFVLNTLSLSADTVEDAE
KWLTGLELLRQETLVAHTPEIIESWLRKQMYSVDQTKKNSITLKELKSLLPQMNFKVPGG
RFLKDRISVVGAKKECLDFEQFHKFYNLLIFENQKMILEEFKKESCAFIMGINDQNIQLS
DFQRFLLYQQRDTWANNVNQVRELMTIFIDDTMRKTNDPAFTVEEFLSFLFSKENSIWDE
KFSEIRTLDMNNPLSHYWINSSHNTYLTGDQLRSESSTEAYVRCLRLGCRCIELDCWNGP
DEPIIYHGWTRTSKIKFKDVVKAINDHAFATSEYPLVLSIEEHCDIKQQKMMAQVFKDVF
QDKLLMEPLEPEAEQLPSPTQLKGKIILKHKKLNLDGTFGKKDLRKGDKQGELFIWDPID
ERWYKHYCVIENKTLYYAEENELEDDVGKSSQGGTELHQSEPWFHGRMSEGRQTAERLLQ
EYCADSGGVDGTFLVRESDTFVNDCTLSFWRSGRVQHCRIRSCIDGGHTVYFLTENLHFP
SVYALIQYYRENLLRCQDFYLRLTELVPRPDQHLREGWFYSNLSRGEAEDYLMRIPRDGA
FLIRQREDSDSYAITFRGEGMVKHCRIHKDGSMYVLGTSSEFESLVELVDYFRKKALYRK
IKLRYPVTPELVERFSSITKTASLYDSKQYVEANEIEPSLPQSTVKALYDYRAMRPDELS
FSKGSLIHNVTKEANGWWKGDFGGKLQHYFPSNYVEEVANTSDANYQPEDENPLGDLCKG
VVDISKCTVVRSAKHGKPVVVTLQDKENKENMMPFDLATETTEELYEWYQVAWDITQREE
NREFEKIKQREVENKEEVASEMSELVVYCQPRSKDKDRFDNYTYKEVRSFVENKVPSRNK
STQFMLYNRKSLSRIYPKGQRVDSSNYDPYPLWMLGCHMVALNFQTADKYMQLNSALFSL
NGGTGYVLQPEMMRRDSYDPHQEKKNVRSTLAIRVIGARHLPKPGRSIASPFVEIELCGQ
TEDNKVKTTVCHDNGLNPVWLGPNSQPSETFTFNVYEPDLTFLRFVVFEEDMFSDPNFLA
QATFPVKGIRSGYRSVPLKNGFSENLELATLLVYVDIQKVEKAQEELYSSSKQLQKKQAE
LSKEFCLYDTHSNLQRAATPNRREDFSQEFTYSEKKLNKQQQKINNSKFYS
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggcaggccgcactcagcagggagacctgaccgagtacaagaagagtctcattaagcgg
gacttggagatggggatagtgatgacagtgtacagacagaggatggagaggcttaccgtg
caggtcatcatggagacgcgacaggtggcctggacgcgcactgccgacaagacagaagga
gtgttggacctttttgaaatccgggaagtacgaccaggaaaaaattccaaagaatttgat
cgattcaaggacaccaaggataaaaattcagaccccaacacatgctttaccatattctat
ggctctcagtttgttctcaacacactcagtctgtcggctgatactgtggaggatgcagaa
aaatggctgacaggactggagttactcagacaggagacactggtggctcacacaccagag
attatagagagttggctgaggaagcagatgtactcggttgatcagacaaagaaaaatagc
attaccttgaaagagctcaagtctcttttgccacaaatgaacttcaaagtgccaggtgga
cgttttttgaaggacagaatttcggtggtgggagcaaagaaagaatgcctagactttgag
caatttcacaaattctacaatcttttgatatttgaaaaccaaaagatgattctagaggag
tttaaaaaggagtcatgtgctttcatcatgggtatcaacgatcagaatattcaactctcc
gattttcaaagattccttttatatcagcaaagagatacatgggccaacaatgtgaatcaa
gtcagagagctgatgactatatttatcgatgacaccatgaggaagactaatgatcctgcc
ttcactgttgaagagtttctcagttttctcttctccaaagaaaactcaatttgggatgag
aagttctcagagattcgtacactggacatgaacaatcctctgtctcactactggatcaac
tcttctcacaacacatatttgactggagatcaactgcgcagtgagtcctcaacagaagct
tatgtgcgctgcctgaggctgggctgccgctgtattgaattggactgctggaatggtcca
gatgaacctattatataccacggctggaccagaacctccaagataaagtttaaggatgtg
gttaaggccatcaatgatcatgcttttgcaacatctgagtatcctttggtgctatccata
gaagaacactgtgacatcaagcaacagaaaatgatggctcaggtgttcaaagatgttttc
caggacaagcttctgatggagccactggaaccagaagcagaacaactgccatcaccaacc
caactgaagggcaagatcatcctcaagcacaagaaactgaatcttgatgggacttttggc
aaaaaggatctacgaaaaggagataagcaaggagagctcttcatctgggatccaatagat
gagagatggtacaagcactactgtgtgatcgagaacaagacattgtattatgctgaggag
aatgaactagaggacgatgttggaaagtcgtcccagggaggtacagagcttcatcagtca
gagccctggtttcacgggcggatgtcagagggcagacagactgctgagagactgctgcaa
gaatattgtgcggattcgggtggagttgatggaacgtttttggtgcgggagagcgacacc
ttcgtcaatgattgcaccctctcattctggcgcagtggacgagttcagcattgtcgaatc
cgttcctgcatagatggaggtcacaccgtctatttcctcacagaaaacctgcatttcccc
agtgtgtatgcactcatccagtattacagggaaaacctgctccgctgtcaagatttctac
ctgcgcctgaccgaacttgtgcctcgaccagaccagcacctgcgtgaagggtggttttac
agtaacttgagccgaggtgaggcagaggactatctcatgaggatccctcgagatggagcc
ttcctcatcagacagagagaagattcagactcttacgccatcaccttcagaggtgaaggg
atggtaaagcactgccggatacacaaagatggatccatgtacgtgctgggcacctctagt
gagtttgagagtctggtggaattggtcgactatttcagaaagaaagcgttatatcggaag
atcaaactccgctacccagtcacaccagaactagttgagcgcttcagttcgataaccaaa
actgcttcactttatgattctaaacagtatgtggaggccaacgagatagagccatctctg
ccccagagcactgtgaaggccctctatgactacagggccatgcggccggatgaactctcc
ttttccaagggctctttaatccataatgtgactaaggaggcaaatggatggtggaaagga
gactttggtgggaaactgcagcactatttcccttcaaattatgtcgaagaagtggccaat
acatctgatgccaattaccagcctgaagacgaaaatccattaggtgacttatgcaaaggg
gtagtggacatctcaaagtgtactgttgttcgctcagccaaacatggcaaacctgtggtg
gtgacgttgcaagataaggaaaataaagagaacatgatgccatttgatttggccaccgag
accactgaggagctgtacgagtggtaccaggtggcctgggacatcacacagagagaagaa
aaccgagagtttgagaaaataaaacagagggaggtcgagaacaaagaagaggtggccagc
gagatgtctgaactggttgtttactgccagcctcgcagtaaagacaaggaccgctttgat
aattatacctacaaagaggttcggtcctttgtagaaaataaggttccttccagaaacaag
tcgactcaatttatgctgtataaccgcaagtcgctgagccgcatctaccctaagggccag
agggtggattcttccaactatgatccgtatccactatggatgctcggctgtcacatggtg
gcactcaactttcaaactgctgataagtacatgcagctgaacagcgctctcttcagtcta
aatggaggcacaggatatgtgctgcaacctgagatgatgcgcagagactcctatgaccct
catcaggagaagaagaatgtcagatctactctcgccatcagagtgataggagcacgacat
cttcccaaaccagggcgaagcattgccagtccctttgtggagattgaactgtgtggccaa
acagaagacaacaaagtcaagactaccgtctgccatgacaatggactgaaccctgtatgg
ctcgggccgaactctcagccttcagagacatttactttcaacgtgtatgagccggacctc
acctttctacgttttgtggtctttgaggaagacatgttctctgaccccaatttcctggcc
caggctacattccctgtgaaaggcattcgctctgggtacagatcagtgcctttaaagaat
ggatttagtgaaaacctggagctggcaactctattggtgtatgttgacattcagaaggtg
gagaaagcacaggaagaactctactcttcctcaaaacagttgcaaaagaagcaggcggag
ttgagcaaagagttctgcctctatgacactcactccaacctgcagcgcgccgcgactcct
aatcggcgcgaggacttctcgcaggagttcacttactcggaaaaaaagttaaataaacaa
cagcaaaaaataaacaacagcaagttctactcatga

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