Pimephales promelas (fathead minnow): 120462651 Help Entry 120462651         CDS       T08155                                  Symbol plecb Name (RefSeq) plectin isoform X1   KO K10388   plectin Organism pprm  Pimephales promelas (fathead minnow) Pathway pprm04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pprm00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     120462651 (plecb)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:pprm04812]     120462651 (plecb) Cytoskeleton proteins [BR:pprm04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     120462651 (plecb) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Plectin Spectrin_4 CH SR_plectin_7 Spectrin_2 SH3_10 Motif Other DBs NCBI-GeneID:  120462651 NCBI-ProteinID:  XP_039507193 LinkDB All DBs Position Unknown AA seq 4942 aa AA seqDB search MDKDAPCPTPSKPKVEKTPKTTKDVQEQPVKNEKADDTSIAPHHEPGANVDEAKSNTSVS SQVPVKSLESAVPLLQHKQENSAIQIAEKKSETNLPQHTFEPSVEESASKSAITASSTVQ MTDKQQIVLASQKTKETQDASKHDNTSPLKVHEKVEIPHAISTAEVKGHKPDLSPKSQSP FKGAEVKITTAVSSKTLTSNIETPKQIDPVQQSAKQTEEPAVTGEAKVAKDTDTEDASKP QKGKKKKQKSPAVKQVPATISETQVTTAQDAGQVEGPEQVATNDSAKTSPEGMRAVVSVP PTAVQNEAPVHKGEVEPEKREVLRGKTSSSQRQREAPAASAQLTPLPKRGEPPSVAQHTA APDTQQSSEQQRSKAPVLTGPLPANKVTCDVQKQSTDDAMRKKIVVVEEVIEVQQIASPV AGEPATPALTEVAGDDLDYDVLEELAKERGLLSDEETWDHSLQEPEGKVFPNFIEDERDR VQKKTFTKWVNKHLIKTQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERGRMRFHKLQN VQIALDFLRRRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMSAKE KLLLWSQRMVEGYHGIRCDNFTTSWRDGKLFNAVIHKHEPRLIDMSKVYHLSNLENLEQA FSVAEQKLGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDVQDGGKAKELELRWT EYYELITVLYQWIRHHITIFEERKFPSSYEEIEILWRQFLKYKETELPARESDKSRSKHL YQSFESAVHAGQVKVPPGYHPIDVEKEWGRLHMAILERERLLRIEFERLERLQQIVSKVQ MESGMCEEQINQTESLLQTDIRLLNAGKPAKHTVEVERDLDKADGMIRLLFNDVQLLKDG RHLQAEQMYRRVYRLHERLVNLRSDYNLRLKSSVSTTQVSMTQVSQRSTQRVRPELDEVT LRYAQDLLAWVEENQRRIDSSEWGNDLPSVESQLGSHRGLHQTIEDFKAKIERARTDENQ LSPASKGTYREYLGKLDLQYNKLLNSSKSRMRNLDQLYNFVSAATKELMWLNDKEEEEIN YDWSEHNTNMAAKKENYSGLMRELELREKKVNDIKTTGDRLIKDGHPGKKTVEAFTAGLQ TQWSWILQVCCCIETHLRENTAYFQFFADVRDAEERMKKMQETMKKKYMCDRTVTSTRLE DLLQDAVEEREQLNEFKTDIAGLNKRAKSVIQLKPRDPTTSVRGKLPIQAVCDFKQMEIT MHKGDECALINNSQPFQWKILHRSGNEAVVPSVCFLVPPVNKDAVESVSSLESGHQQTLV LWQKLHADLRSLLSWQYLMKDIHLIRTWNITMFKTMKPDEYQLILRNLQLHYQDFLKDSQ ESKMFDSTDKMQIERDYKETTLYFDKLLHTLEKGEQDESTSKSYITQIKNLRLQIEDCES RTVARIRQPAGKDPLKDCIQKTADQRKVHVELEGIKTNLDKVSQKAEEVLASPEQSSSPV LRSELDITLQKMDQTYNLSSVYLQKLKTIEVVIRNTQEAENVVKIYENRLRDVHTVPANV QEVENYCSELKKMRVEAETQRPVFDDMEGELAKATSVSQNMSRIHTERDAELDHYRQLLG SLQDRWRAVFAQIDLRHRELEQLGRQQGYYRESYDWLIRWIADAKQRQEKIQAVPITDSK TLKEQLAQEKKLLEEIEKNKEKVDECQKYAKAYIDTIKDYELQLVAYKAQVEPLTSPLKK TKMESASDNIIQEYVTLRTRYSELMTLTSQYIKFITDSQRRLEDEEKAAEKLKAEERKKM AEMQAELEKQKQLAEAHAKAIAKAEKEAQELKLMMQEEVSKREIVAVDAERQKQNIQLEL HELKNLSEQQIKSKSQQVEEALQSRSKIEQEIHIIRLQLETTVKQKSTAEDEVRQLRDKA AEAERLRKVAQEEAEKLRKQVNEETQKKRMAEEELKLKSEAEKEAARQKQKALDDLEKFK MQAEEAERHMKQAEMEKERQIKVAQEAAQKSATAELQSKRMSFVEKTSKLEESLREKHGT VIQLQEEAERLKRLQEEADKGREEAESELEKWRQKANEALRLRLQAEEEAHKKSLAQEEA EKQKDDAEREAKKRAKAEESALKQKDMAEQELERQRKMAESTAQQKLSAEHELIRLKADF DHAEQQRSLLDDELYRLKNEVSAAEQQRKQLEDELSKVRSEMDILLQMKSKAEKDSMSTT EKSKQLLEAEAAKLRDLADEAAKLRAIAEEAKRQRQVAEEEAARQRAEAERILKEKLTAI NEATRLKTEAEIALKEKEAENERLRRNAEVEAYQRKALEDQASQHKQDIEQKIDQLKKSS EMELERQKSIVDDTLKQKRIVEEEIRILKLNFEKASSGKLDLELELNKLKNIAEETHQSK LRAEEEAEKLRKLALEEENRRREAEEKLKKITAAEQEAGRQRQVAQEEVERLKKKADEAR KQREDADKEAERQIRAANEAAEKAITAEQQVQSVLVQQKEDSMVHKRLKEEFEKAKKLAQ EAEKAKQKAEKEAALLRHQAEDAERQRQAAEVEANNQAKAQEEAERLRKEAELEAEKRAQ AEAAALKQKQLADEEMARHKKHAEQTLKQKSQVEQELTKVKLRLDETDKQKTLLDDELHR LKDEVGDAVKQKAQVEEELFKVKIQMEELIKLKLRIEEENQRLIQKDKDNTQTFLAEEAE NMKKLAEEAARLSIEAQEAARMRHIAETDLAEQRALAEKMLKEKMQAIQEASKLRAEAEM LQRQKDLAQEQAQKLLEDKQMMQQRLEEETEGFQKSLEAERRRQLEITAEAEKLRLQVSQ LSDAQTRAEKEAKKFKKQADEISARLHETELSTKEKLTVVEKLEIQRLSSNKEADDLRKA IADLENEKAKLKKEAEELQKKSKEMANAQQEQIKQEKTILQQTFMSEKEMLLKKEKQIED EKKRLESQFEEEVKKSKALKDEQERQRKQLEDEKMKLKATMDSALMKQKAAEKEMLNKQK EMQDLERKRLEQERMLAEENQQLREKLQQLEVAQKITQEIHIQTEYKKVLNGQRISDEAD GPNGFSALSFDGIREKVPASRLFDVGLLSKMDYEKLQNGDTTSQELSKTEKLKTVLKGKN SIGGLLVHPNQKMPIYQAIKEKKIAPGTGLVLLEAQAASGYIIDPIKNKKLSVNEAVKEG LIGPELHNKMLSAERAVTGYKDPYTEAKISLFEAMKKGLIGEDHAIRLLEAQIATGGIID PVNSHRVPTEMAYKQGQFDAATNKILQNPTDDVKGFYDPNTQENLTYHQLIERCVTDPET GLLLLPISEEAALNARIFTDEETRDVFDKTTVSVPFGRFKGKTVTIWEIINSEYFTEDQK KDLIRQYKTGKITVEKIIKIVLTVAEEKEKKNELAFEGLRAPVPATKLLESKVIDKDLYN KLQKGQLLVKDVSEMEHVRSALKGTNCIAGVIIDSTKQTMSLYDAMKRDMMRPGPALNLL EAQAATGYVVDPIKNQKLTVDEAVKAGVVGPELHEKLLSAERAVTGFKDPYTGKTISLFE AMKKDLIMKDQGFRLLDAQLATGGIVDPVQSHRIPHDIACMKGSFDDATHKILTSPTDDV KGYFDPNTQEYVTYLQLYKRCVTDKKTGLQLLPLSEQAINAKEEFKYTDDQTKDSMTQAT VEIQSGHLKGRKVTIWELINSDYLTEEQRLDLIRQYRSGKMTIEKITKIIIEIVTEKDAK KQEEGCFKGLRAPVPAKSLFDSKIIDKSTYDLLEQGKKTPKEVSKNTSVNKYLQGSESIA GVYLEPTKEKVSIYQAMRKKFLRQNTGIALLEAQAATGFIVDPSRNECLTVDDAVKAGLV GPELHEKLLSAEKAVTGYKDPFTGNKISLYQAMEKDLILKEHAMPLLEAQLAAGGVIDPV NSHRIPVEIAIHRGYVTKQLASSIAESKYFSDPASDENISYKQLKDKCMTDPDTGLNLLK LSKPQAPTVVEKTYLYSEEQTQSDLTTTHVDLPIEGQGSMSLWDVMNSNLLPEEQRSQLL DEYRSGSITKERMIIIIIEILEQREIIKGGNIQTGGTRRRQITIEDLYNARIIDLETFNL LKKEKKTMRDVMEMQSVKQYLYGTGSVSGVVTDSNSKISIYQAMKREMMKPDIAIGLLEA QAATGFIIDPVRNEMLTVDEAVRKGVVGPEIHDKLLSAERAVTGYKDPYSGKIVSLFQAM KKDLVSEDYALRLLEAQTATGGIIDPEYNFHLPTEIATQRGYINKETYEKLSDEVKGCVD PLTDEKLSYAQLLKRCKVDKDGLYLLSLADRRLLFKGLRKEITIEELYRSKIIDEQTVSE LNEGLLTVDEVSNRLRKYLQGSSCIAGVHVESTKDRLSIYQAMKKNMIRPGTAFELLEAQ AATGYIIDPIKNLKLTVNESIKMGIVGPEFKDKLLSAERAVTGYRDPYTGKMISLFQAMK KGLILRDHGIRLLEAQIATGGIIDPEQSHRLPVEVAYNRGFFDEEMNEILSDPSDDTKGF FDPNTEENLTYLQLMERCIVDPDTGLVLLLLKEKKREKQSSTKSSVRKRRVVIVDPDSGK EMSVYEAYRKKLIDHDTYLELSEQECEWEEITMTSSEGVEKSILIDRRSGRQYDIEDSIA RGLIDQSTIDQYRSGTLSITEFADMLSGNMSGFRSRSSSFGSTSSYPMSPVPTIKTPATV WNDPSEETGPVAGILDTDSLEKVSVTEAMHRNLVDSITGQRLLEAQACTGGIIDPSTGDK FPVAEATEKGLIDKIMVDRLNLAQKAFHGFDDPRTKVKMSAAQALKKGWLYYEAGQRFLE VQYLTGGLIEPEAEARISLEEAIRKGAIDGRTAQKLRDVSGYSKYLTCPKTKLKISYKDA MDRSMVEEGSGLRLLEASSTSSKGLYSPYNVSGAASASGSRTGSRTGSRTGSRRGSIDAT GSGFSLNFSSSSFTSSSYNRRF NT seq 14829 nt NT seq  +upstreamnt  +downstreamnt atggataaggatgctccttgtcctactccatcaaagccaaaagtggagaaaacgccgaaa accacaaaggatgtgcaagaacaaccagtcaagaacgaaaaagcagacgacacctctatt gcaccacaccatgagcctggtgccaatgtggatgaggcgaagtcaaatacctctgttagc tctcaggtgcctgtcaaatctctagaatcagcagtgccacttctgcaacataaacaagaa aattcggcaatacaaattgctgaaaagaaatcagagactaatctaccacagcacactttt gagccttctgtagaggagagtgccagtaagtcggccatcacagcatctagtactgttcaa atgactgacaagcaacagatagtacttgcgtcccaaaaaacaaaggaaacccaagatgca tcaaaacatgacaacaccagtcctttaaaagttcacgaaaaggttgagattcctcatgct atatctactgctgaggttaaaggtcacaaacccgatctcagccctaaatctcagtcccca tttaaaggtgctgaagtgaagattaccacagctgtctctagcaagactttgacatcaaac atagagacgcctaaacaaattgatcccgttcaacaatcagcaaaacagactgaggaacct gcagtcacaggagaggccaaagttgcaaaagacacggatacagaggatgcctcaaagcct caaaaaggaaagaagaaaaagcagaaatctcctgctgtaaaacaggtccctgcaactatt tctgagactcaagtgacaacagcccaggacgcaggtcaggttgagggtcctgagcaagtt gcaacaaatgactctgcaaagacatcccctgaaggaatgcgtgctgtggtgagcgtgccg ccaacagctgtgcagaacgaggccccggttcacaaaggggaggtggagcctgaaaaacgg gaggttctgagaggaaaaacatcctcctcgcagagacagagggaagcaccggcagcctcg gcccagctcacccccctccctaaacgaggggaacctcccagcgttgcacaacacacggct gctcctgacacacagcagagctcagagcagcagagaagcaaggcccctgtcctcactgga ccccttcctgccaacaaggtcacctgcgacgtgcaaaagcagtccacagacgacgccatg cggaagaagattgtcgtggtcgaggaagtgattgaagtgcaacagattgccagtcctgtt gcgggagaacctgcaacacccgctctgacagaggttgcaggagatgatttggactatgat gtcttggaagaactggccaaagagcgtggcctcctgtccgatgaagagacttgggatcat tcactacaagagccagaaggcaaagtcttccccaacttcattgaagatgaacgggacaga gtgcagaagaagactttcacaaaatgggtgaacaaacacttgataaagactcagcgtcat gtgaatgacctgtacgaagatctccgagatggacacaacctgatctcccttctggaggtc ctctccggggagacgctgcctcgtgagagaggacgcatgcgattccataaactgcagaat gtgcagatagcactggatttcctcagacgccggcaggtcaagctggtgaatatcaggaat gatgacattgccgacggaaacccaaagctgacattgggtctcatatggaccatcatcctt cacttccagatttcagatatccaggtgaacggtcagtcagatgatatgtcagcgaaggaa aagctgctcctctggtctcagcgtatggtggagggttatcacggtatccgctgcgataac ttcaccactagctggagggacggaaaactcttcaatgcggttatacacaaacatgagccc aggcttatcgacatgtcgaaagtataccacctatccaacctggagaacctggaacaggca ttttcagtggcagagcaaaaacttggggtcactcgactgcttgacccagaagatgtggat gtgcctcatcctgatgagaagtccataatcacctacgtctcctccctgtacgacgctatg ccacgagttccagacgtccaggacggcggcaaagccaaagagctggagctgcgctggact gaatactatgagctgatcaccgttctataccaatggatcagacatcacattaccatcttt gaggagaggaagtttcccagcagctatgaggagatcgagatcctatggcgtcagtttctg aaatataaagaaaccgagctgcccgccagagagtcggacaagagccgctccaaacacctc taccagtcctttgagagtgcggttcacgctggtcaggttaaggtccctcctggttatcac cccattgatgttgagaaggaatgggggcgtctgcatatggccattctggagagagagaga ctgctcaggatcgagtttgagaggttagaacgtctccaacagattgtcagtaaagtgcag atggaatcaggcatgtgtgaggaacaaatcaaccagacggagtctctactgcagacggat attcgtctcctgaatgcggggaaaccagcgaagcacacagtagaggtggagagagatctg gacaaagccgatggcatgatccgtctcctctttaatgacgttcagcttctcaaagatggg cgccacctgcaggcggagcagatgtatcgcagggtctaccgcttacatgagcgcttggtg aacttgcgcagtgactacaatctaaggctcaagtccagcgtcagtactactcaagtctcc atgacccaagtctcccagaggtctacgcaacgcgtgcgacccgagctggatgaggtcact ctccgatacgcacaggacctgttagcctgggtggaggagaaccagcgcaggatcgattcc tccgagtggggcaatgatcttccgtctgtggagtctcagctgggaagccacagaggtctt caccaaactatcgaggacttcaaggctaagattgagcgagcacgaacagatgagaaccaa ctctcgcctgccagcaaaggcacatacagagaatatctgggcaaactggatctgcagtac aacaaactgctgaactcctccaagtcccgtatgagaaatcttgaccaactatataacttt gtcagtgccgccaccaaggaactgatgtggcttaatgacaaagaggaagaggagatcaat tacgactggagtgaacacaacaccaacatggctgcaaagaaagagaactactcaggactc atgcgtgaactggaactgagggagaagaaggtcaatgacatcaagaccactggagacaga ctcattaaagacggccatccaggcaagaagactgttgaggccttcaccgcaggtctgcag acccagtggagctggatccttcaagtgtgctgttgcattgaaactcatctcagagagaac actgcatactttcagttctttgctgatgtaagagatgctgaggagaggatgaagaagatg caggagaccatgaagaagaagtacatgtgtgatcgcaccgtcacgtccactcgtttggag gatttacttcaagatgctgttgaggaaagagagcagctgaacgagtttaagactgacatc gccggcctaaacaagagagccaaatctgtgatccagctgaagccacgcgaccccaccacc tccgtgagaggaaaactgcccatccaggccgtgtgtgacttcaaacagatggagatcacg atgcacaagggcgacgagtgcgcgctcatcaataactcccagcccttccagtggaagatc ctgcaccgctcgggcaatgaggccgtcgtgccgtctgtctgcttcctcgtgccgcccgtc aacaaggacgctgtcgagagcgtctccagtctggagtctggtcaccagcagacactggtt ctctggcagaaactacatgctgacctcaggagtctgctgtcctggcaatacctgatgaag gacatccatctcatccgcacatggaacatcactatgttcaagacgatgaagccagacgag taccagctgattttgaggaaccttcagctgcactatcaggactttctcaaagacagccag gaatcaaagatgttcgattcaactgacaaaatgcagatcgaaagggactataaggagacc acgctgtatttcgacaaactgctccacaccctggagaaaggtgagcaggatgaatccaca agcaagtcatacatcacccaaatcaaaaacctgcgcctgcagatcgaagattgtgagtct cgcacggtggctcgtatccgccaacctgcggggaaagatccgctcaaagactgcattcag aagactgcagatcagaggaaagtgcacgtggagttggaaggcattaagacgaacctggat aaagtgtcccagaaagccgaggaggtcctggcgtccccggagcagtccagctcgcccgtc ctgcgctcagagctggacatcaccctgcagaagatggaccaaacctacaacctgtcctca gtgtacctgcagaaacttaagacgatagaagttgtgatccggaacacgcaagaggcagaa aatgtggtgaagatttatgagaatcgcctgcgtgatgttcacacggttcctgcaaacgtc caggaggtggagaactactgttccgagctcaagaaaatgcgtgtggaggcagaaacccag cggcccgtgtttgatgacatggagggtgagctggccaaggccacatcggtcagccagaac atgtctcggattcacactgaacgggacgctgagctggaccactacagacagctcctgggc agccttcaggaccgctggcgcgccgtcttcgcccagatcgacctgcgtcatcgcgagctg gagcagctcggccggcagcagggctactacagggagagctatgactggctcatccgctgg atcgcagacgccaagcagcggcaggagaagatccaggccgtgccgattactgacagcaag acactaaaagagcaactagcacaggagaagaaactgctggaagagattgagaaaaacaaa gagaaagtcgatgagtgtcagaaatatgccaaagcctacattgatacaatcaaggattat gaactacaattggttgcctacaaagctcaggtagaacctctgacttctcctttgaagaaa accaagatggagtcagcctctgataacatcattcaagagtatgtgactctgcgaactcgc tatagtgaactgatgactctgaccagtcagtacatcaagttcatcacagactcgcagcgg cgcttggaggacgaggagaaagctgctgagaaacttaaagcagaagagaggaaaaaaatg gctgagatgcaggcagagttagagaaacagaagcagctagctgaagctcatgccaaggcc attgccaaagcggagaaagaggcacaggagctcaagctcatgatgcaagaggaggttagc aaacgagagattgtcgctgtggatgctgaaaggcaaaagcagaacatccagctggagctg catgagctcaaaaacctctccgaacaacagatcaaatcaaaaagtcagcaagtggaggag gctctgcaaagccggtccaaaatagagcaagagatccacatcataagacttcagttggaa actacagtaaagcagaagtccaccgcggaggacgaggtgaggcagcttagagacaaggct gcagaggcggagagacttcgcaaagttgcccaggaggaggctgagaaacttcggaagcag gttaatgaggagacccagaagaagcggatggcggaggaggagttaaagcttaagtctgaa gcagagaaagaggctgccaggcagaagcagaaagccctggacgaccttgagaagttcaag atgcaggctgaggaggcagagagacacatgaagcaggctgagatggagaaagaacgacaa atcaaggtcgctcaagaggcagctcagaaaagtgccactgctgagctgcagagtaagcgc atgtcctttgtcgagaagacgtccaaacttgaggagtcactccgagaaaagcacgggacc gtcattcaactgcaggaggaggcggaacgcctcaaaaggctacaggaagaggcggacaag ggaagggaggaggctgagagcgagcttgaaaaatggaggcaaaaagccaatgaggccctt cgtctaaggctccaggcagaggaagaggcccacaaaaagagtcttgcacaggaagaggcc gaaaaacagaaagatgacgctgagcgcgaggccaaaaaacgggccaaagctgaagagtct gccctgaaacagaaagacatggctgagcaagaacttgagcggcagaggaagatggccgaa agcacagcacaacagaagctttcggcagagcacgagctgatccgcctgaaggccgatttt gatcatgccgagcaacagagatctctgcttgatgatgaactgtaccgtctcaagaatgag gtcagtgctgcggagcagcagcggaagcaacttgaagacgagctttccaaagtcagaagt gaaatggacatccttttgcagatgaaatctaaggctgaaaaggacagcatgtctaccact gaaaagagtaaacaactcttggaagctgaagctgctaaactgagggatcttgcagatgaa gcagccaagctccgtgccattgctgaagaggcaaagaggcagaggcaagtggctgaggag gaagctgcgaggcagagagcagaagcagagagaattctcaaagaaaaactcactgccatt aatgaggccactcgcttgaagactgaggcagagatcgctcttaaagaaaaggaggctgaa aatgaacgcttgagaaggaatgctgaggtcgaggcttaccagagaaaggctcttgaagat caggcaagccagcacaagcaagacatcgagcagaagatcgaccagctcaagaaatcctct gaaatggaattggaaagacaaaaatcaatcgtagatgacactcttaaacagaaaagaata gttgaagaggagatccgcatcttgaaacttaattttgagaaggcttcatctggcaagctt gatttggagcttgaattgaataagctgaagaacattgctgaggaaacgcaccaaagcaaa ctacgagctgaggaggaagccgagaagctacgtaagctcgcccttgaagaagaaaacaga agaagggaggccgaagaaaaactgaaaaagattactgccgcagaacaggaggcaggccgg cagcgccaagttgcccaagaagaagtggagcgtctcaaaaagaaagcggatgaggccagg aagcagagagaagacgctgataaagaagccgagaggcaaatacgtgctgccaacgaggct gctgagaaagcaattacagctgaacagcaagttcaaagcgttcttgttcaacagaaagag gacagcatggtgcataaaaggctcaaggaggagtttgagaaagctaaaaagcttgcccaa gaagcagaaaaggccaaacaaaaagcagagaaagaggctgccctcctccgccatcaagcc gaagatgccgaacgtcagcgtcaggctgccgaggtcgaggcaaacaatcaggccaaagcc caagaagaggctgagaggctcagaaaagaggcagagcttgaggcagaaaagcgagcccag gccgaggcagcagcgctgaaacaaaaacagctagctgatgaagagatggctaggcacaag aaacatgcagagcagactcttaagcagaagtctcaggtcgagcaagagctcactaaagtg aaactgcggttggatgagaccgacaaacaaaagactctcctggacgatgagcttcatcgc ctgaaggacgaggttggtgacgctgttaagcagaaagcccaggtagaggaggaactgttc aaagtcaagattcaaatggaagagctaatcaaacttaagctcagaatcgaagaggagaat cagcgtctcatccagaaggacaaagataacactcaaacgttcttggctgaggaggccgag aacatgaaaaagcttgctgaggaggctgccaggctcagcatcgaggcccaggaggctgct cgcatgagacatattgcagagactgaccttgcagagcaaagagcacttgctgagaagatg ctcaaagaaaagatgcaagccatccaggaggcgtctaaacttagagcagaggcagaaatg ctacagagacagaaagaccttgctcaagagcaagcccagaagctgcttgaagacaagcaa atgatgcagcaacggcttgaggaggaaaccgagggcttccaaaaatcattggaggccgaa cgcaggagacagttggagataacagctgaggcagagaaacttagacttcaggtttcacag ctcagtgatgcacagactagagctgagaaggaagccaagaaattcaagaagcaggcagat gagattagtgcccgacttcacgagaccgagctttccaccaaagagaaattgactgttgtt gaaaaattggaaatacagagattgagcagtaacaaagaagcagatgacttgcgcaaagcc attgctgatcttgagaatgagaaggcaaaattgaaaaaagaggctgaagagttacagaaa aagtccaaagagatggcgaatgctcagcaagaacaaattaaacaagagaagactattctt cagcagacatttatgtcagaaaaggagatgcttttgaagaaggaaaaacaaattgaggat gaaaagaagaggttagagagccaatttgaagaagaggtcaaaaagtcaaaagccctgaaa gatgaacaggaacgtcaaagaaaacaactggaggacgaaaagatgaaacttaaggccacc atggattctgctctgatgaaacagaaagcagctgaaaaggagatgctcaacaagcagaaa gagatgcaagaccttgagaggaaaaggcttgaacaggaaagaatgcttgctgaggaaaac cagcaactgcgcgagaaacttcagcagcttgaggttgctcagaaaatcacccaggaaatt cacatccagaccgaatacaaaaaagtcctcaatggtcaaaggatttctgatgaagctgac ggcccaaatggtttctctgcattatctttcgatggcattcgtgagaaagtacctgcaagc agactttttgacgtaggacttttaagcaaaatggattacgaaaagctccagaatggtgac accacaagccaagaacttagcaagacagaaaaacttaaaacagttcttaagggcaagaac tccattggtggcctgcttgttcatccgaatcaaaaaatgcccatctatcaagccatcaag gagaagaaaattgctcctgggactgggcttgtcctgctggaggcacaggccgcttctgga tacataattgacccaattaaaaacaagaaactctctgtcaatgaggcagttaaagagggt ctaattggacctgaacttcataacaagatgctgtctgcagagagagctgtcactggttac aaggatccatacacagaggcaaagatctccctctttgaagctatgaagaagggtctcatt ggggaggatcatgccatcagattgcttgaggcccagatagcaacaggtggcattattgat ccagtcaacagtcatcgtgtgccaactgaaatggcctataagcagggtcaatttgatgca gccaccaataaaattctacaaaatccaacagatgatgtcaagggattctatgatccaaac acccaagaaaatctgacctaccaccagctaatagaaagatgtgtcactgatccagaaaca ggactgcttcttttgcccatctctgaggaggctgctctaaatgccagaatattcacagac gaagaaacaagggatgtctttgacaagacaactgtgtctgtgccatttggaaggtttaaa ggaaagactgtgaccatctgggaaattataaactcagagtacttcaccgaggatcagaaa aaagatcttatccgtcaatacaaaactgggaaaattacagttgaaaagatcatcaaaatt gttctaactgtggccgaggaaaaagagaaaaagaatgagcttgccttcgaaggcctgaga gcacctgtacctgctacaaaacttcttgaatccaaagttattgacaaagacctctataac aaattgcagaaaggacaactgctggtaaaagatgtgtctgagatggaacatgtgcgcagt gctttgaaaggcactaactgcattgcaggagtaattattgactcaaccaaacaaacgatg tccttgtatgatgccatgaaacgagacatgatgagacctgggcctgctcttaatctcttg gaagcacaagctgctacaggatatgtcgtagatcctattaaaaaccaaaagctcacagta gatgaggctgtaaaagcaggtgttgtcggtccagagcttcatgaaaaactactgtccgca gagagagctgtcacaggcttcaaagatccttacactggaaaaactatttctctgtttgag gctatgaagaaggatctgatcatgaaggaccagggattccggctgcttgacgcacaactg gctactggaggcatcgttgatcctgttcaaagtcaccgtattccgcatgacattgcctgc atgaagggcagttttgatgatgcaacccacaagattttgaccagcccaactgatgacgtt aaaggatattttgacccaaacactcaggaatatgtcacttatctgcagctttataaaaga tgtgtcactgacaaaaagactggccttcagcttcttcctttgtctgagcaagccatcaat gccaaggaggagtttaagtatactgatgaccagaccaaagactcaatgactcaggcaact gttgaaattcagagtggacatttgaaagggagaaaagttaccatatgggagctcattaac tcggattatctcactgaggagcaaagacttgacttaataaggcaatacagatctgggaaa atgacaattgagaaaattacaaagattataattgaaattgtcactgagaaagatgccaag aaacaagaagagggctgctttaagggacttagggcgccagttcctgccaagtcattattt gactccaaaatcattgacaagtcaacctacgatttgctggaacaaggtaaaaagactcct aaagaggtaagcaaaaacacttcagtcaacaagtatctccaaggctctgagagcattgct ggagtttaccttgagcctacaaaagagaaagtcagcatctaccaagcaatgagaaagaaa ttcctcagacaaaacacaggtatcgctttgcttgaagctcaagctgctacaggattcatt gtggatccatcaagaaatgaatgtcttactgtggatgatgcggttaaagcaggccttgtt ggtccggagcttcatgagaaacttctctctgctgaaaaagctgtcactggatataaagac ccattcactggcaataaaatctccctgtatcaagccatggagaaagatcttatcctcaaa gaacatgccatgccactcttggaggcacagttggctgcaggtggagtaatcgatccagtg aacagtcatcgtattcccgtcgaaattgctattcaccgtggctatgttaccaaacagctg gccagcagcattgctgaaagcaagtacttctctgaccctgcatctgatgagaacatatca tacaaacagttaaaagacaagtgtatgacagatcctgacacgggtttaaatctactaaag ctctccaaaccacaggccccaacagttgtggagaagacatacctttacagtgaagaacaa actcagagtgatctaaccactacccacgtcgatctacccattgaaggtcagggctctatg tctctctgggatgtcatgaattcaaatctactacctgaggagcaaagatctcagcttctg gatgaatatcgttctggcagcataacaaaggaacggatgataatcattataattgagatt ctggagcagagagaaattattaaaggggggaacatccagacaggcggcacaagaagacgt caaattactattgaagatctctacaatgcccgcatcattgaccttgagaccttcaacctg ttgaagaaagagaaaaagactatgcgtgatgtcatggagatgcaaagtgttaagcagtac ttgtatggaactggcagtgtttctggtgtggtgactgattccaattccaaaatcagcatt tatcaagcaatgaagagagagatgatgaagccagacattgcaattggtctcttggaggct caagcagccactggattcatcattgatcctgtcaggaatgaaatgctcactgtagatgaa gcagtgcgcaaaggtgtagtgggcccagaaattcatgataagctcttgtctgcagagaga gcagtgactggttacaaggacccatatagtggaaagatcgtctccctcttccaagcaatg aaaaaggaccttgtgtccgaggactatgccctaaggctactcgaagctcaaacagcaaca ggcggtattattgatccagagtataacttccacctgccaacagagattgccacacagcgt ggatatattaacaaagagacttatgaaaagctgtccgatgaggtcaaaggatgcgttgat ccattaactgatgaaaagctgtcatatgctcagcttttgaaaagatgcaaggttgacaaa gatgggctatatctgttgtctctagcagacagaaggctgctcttcaaaggtctcagaaaa gaaataacaatagaggagttatatcgctcaaaaatcattgatgaacaaacagtcagcgaa cttaatgaagggctactaacggtggatgaggtgagcaatagattgcggaaatatcttcag ggctcaagctgtattgctggcgtgcatgtggagtctactaaagaccgtctatctatctac caagccatgaaaaagaacatgatcaggccaggtactgcttttgaactgctggaagcacaa gcagccacaggttatataattgaccctatcaagaacctcaagttaacagtaaatgaatca attaagatgggaattgtcggccctgagttcaaagacaagctcctgtctgctgagagggct gtgactggctatagagatccttacacaggcaaaatgatctcactgttccaggcaatgaaa aagggcctgattttgagagaccacggaattcgtcttcttgaagcccagattgctactgga ggaatcattgacccagagcagagtcaccgcttgccagtcgaagttgcctacaaccgaggg tttttcgatgaggaaatgaacgagatcctcagtgacccgtcggatgacaccaagggcttc tttgacccgaacacagaagagaatctgacctacctgcagctgatggaaagatgtattgta gacccagacacaggtcttgtgctcttgcttcttaaagaaaagaaacgcgagaaacagtct tctaccaaatcctccgttcgcaagcgcagagttgtcattgtggatcccgattcaggcaaa gagatgtctgtgtatgaagcctaccgcaaaaagctaattgaccacgacacttaccttgaa ctttcagagcaagagtgtgaatgggaagaaatcacaatgacatcatcagaaggggttgaa aagtctatactcattgaccgaagatcaggtcgacagtatgacattgaggactctatcgca agaggcctcattgaccagagtaccatcgaccagtaccgctccggcaccctctctatcaca gaatttgctgatatgttatctggaaacatgagtggttttcgttcccgatcctcttccttt gggtccacctcctcttatccgatgagccccgtacctaccatcaaaactcctgcaaccgta tggaacgatccgtctgaggagacaggtcctgtggctggaatacttgatacagatagccta gaaaaagtttcagtcactgaagccatgcacaggaacttagtggattctataactggccag agactgttggaggcacaagcttgtactggtggcataatagacccatccacaggagataaa ttcccagttgctgaagccacagagaagggtcttatagataagataatggtcgacagactc aacttagcccagaaagctttccatggattcgacgatcctcgcaccaaagtcaaaatgtct gctgctcaggctctcaagaaaggctggctttattatgaggcaggacagcgtttcctggag gtgcagtatcttaccggcggccttattgagccagaggctgaggcacggatctccttagag gaggcgatcaggaaaggtgccattgatggtcgtacagcccaaaagctccgagatgtgagt ggttactcaaaatatcttacatgtcccaaaaccaaactgaagatctcctacaaagatgcc atggacagaagcatggttgaagagggatctggccttaggcttctggaagcttcatcaaca tccagtaaaggcctctacagtccctacaatgtcagtggtgctgcatctgcctctggatct cggactgggtccagaacaggctctaggacaggttcaagaagaggcagcattgatgctact ggctctggattcagcttgaacttctcatcgtcatcatttacttcctccagttacaaccgc agattttaa

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