Pimephales promelas (fathead minnow): 120467729 Help Entry 120467729         CDS       T08155                                  Symbol scospondin Name (RefSeq) SCO-spondin   KO K24434   SCO-spondin Organism pprm  Pimephales promelas (fathead minnow) Brite KEGG Orthology (KO) [BR:pprm00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:pprm04990]     120467729 (scospondin) Domain-containing proteins not elsewhere classified [BR:pprm04990]  Thrombospondin domain-containing proteins   Other thrombospondin domain-containing proteins    120467729 (scospondin) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TSP_1 TSP1_spondin VWD Ldl_recept_a TIL F5_F8_type_C VWF TSP1_CFP_C Pacifastin_I VWC TSP1_ADAMTS F5_F8_type_C_2 Motif Other DBs NCBI-GeneID:  120467729 NCBI-ProteinID:  XP_039512123 LinkDB All DBs Position Unknown AA seq 5375 aa AA seqDB search MRVVLVCVLALHLAGVMGHWCEHTVQETVERMLSPREQREVDCSSVYQFNTQGWRLDVDR MRHEHGGDDGIALYYKGQGSKASCYIFKPPEIETETLNRTLRQCCEGWAGPHCSHGVGAR GQCFSTWTCEEFPGVGNSSLMTLEQCCGHLWGLSWRNASDQTCLSCTYTLLPDVRSSPVI RGVRDPQASGTCMSWGGTHYRTFDRKHFHFQGSCTYLLASSTDGTWAVYSSSVCDTAGHC RKGLRMMLGLGLVSVHKGNMTVNGVSLPQGEPLFQNGVSVHWLGDFVFVESGLGVRLKFD MENTVYLTVTAEHLTATRGLCGVYNNNPDDDFTTSGGSVSQYAASFGNSWRVQDQQGQVC SDAAELGHSCDLSSDVSLRRDAETACHRLKENPFSHCHHQVDPGPYIDTCLYLFCSLEAS ERETAVCDTLAGYVRECATQHVIIRWRNAGFCERVCPRGQVFSDCVSSCPASCSSPGPAA SGQCRDECVGGCECPPGLVLHAGQCVRRADCPCFHRRRTYSAGDAITQRCNTCVCGAGQW ECSGERCEAQCTVIGAMHVTTFDQKRFSLQSADCQFTAVEDFVDRKLSVGISAGQCSGGS AGCLRELRVTALKTTLTVTDSGSVLVNGQRELLPVVTGDLMVRKSSSSVLLIQAFGARLM WHLDGPLLLITLQPGFAHKVRGLCGTLTWSQHDDFTTPEGDVENSVSSFAAKFRTGSCPL PLAMTSDPCGMYTQRRQYAESVCSVIHSSVFQACHDVVDREPYMRVCLSEVCGCDPLKSC QCTVLAAYARQCAQEGAPLSWRNRTFCSVRCSGGQVYQECGRPCGSSCADLWSGWSCEGD EGRGNCVPGCQCPAGLAQDTQGQCVPVHMCPCTHGGQIYPAGSTRQNNCNTCVCARGVWN CTDLSCPEVHQCPGSLVFSPRSCLRTCSSPISPLDACAEPIHGCVCPDGTVLLGDQCVKP DECPCHHNGRLYFTNDTISKDCNTCVCGEQRWHCGQAFCSGTCVATGDPHYITFDGRHFS FLGDCEYVLAQESSGLFSVSAENVPCGSTGVTCTKSVTLTVGNTAIHLLRGKSVTVNGIP VTLPKVYSGSGLILERVGLFVSLSSRLGVSLLWDGGMRVYVRITPHLRGRVGGLCGNFDG DAENDFTTRQGIMESTPELFGNSWKISPSCPDVPDQDLRDPCAINPHRVTWAKKKCAVIS QEMFGSCHSEVPYQQYYDWCVFDACGCDSGGDCECLCTAVAAYAEECNRRGVYVRWRSQE LCPLQCENGLVYEACGPACSPACPSTPSLSDSLCRSLSCVEGCFCPHGTVRHGEVCIPPS QCPCEWDGSLFPAGAAVTQHCQNCSCSDGAWRCVGSPCPPPSPCEDSEFRCSAGSQRCIP SVWLCDNEDDCGDGSDEVCPFTCPPGRFRCSTGACLPLELRCNGHPDCADQSDEDFCEPH TAEPGCPDGEFRCANGRCLPVRKVCDGRLDCGFADDSDEYDCGAVCRPDEFLCSSGRCVL YLHRCDGHDDCGDYSDERECVCALGELQCPGDQCVSAERVCDGHRDCPSGVDELICPVKG CSQFEFGCTSGQCVPIAWRCDGETDCLDGSDEKPCSRTCQPDQFLCHSGDQCVQHQHLCD GTPHCRDASDESLDNCGSLRIPPCLDSFSCDNRTCVNVSRVCNGVPDCPKGEDEILCDKV RPSTAPPSERNTSHVCPEFTCADGSCVPFNTLCNGAADCVSDGSDETGCGVWGPWSPWSP CSRSCGSGTVSRQRRCHPEDPDGHCRGEQTQRQQCYSTACPVDGYWLPWVTWSNCSQGCG GVEVRQRECFPPQNGGRTCTELPGETPLTVDIKPCPQDGCANVSCPAGLVTHTCAPCPLT CAHVSGATTCDPNADCFTGCWCPDGKVMNHEHQCVLPEECVCEVSGVRYWPGQQVKVGCE MCVCERGRAQRCQPNLECSVHCGWSSWSPWGECLGPCGVQSVQWSFRSPNNPSQHGSGRQ CRGIYRKARRCQTELCSECEYGGHTHTVGERWKGGQCQLCQCLPNFTVQCGPYCPYAATG CPQGQTLIPGEEDKCCYCEEKGDITTVVTPTPMVLPITVGPSTPPEGPPTVPTYPLPPGD ECWSSLGVPSLPDSSFSASSHQPDHPPSAGRLHARDPRGDLQGWSPEPKEYRELSTGTPE ETGPSTGPFLQIDLLRRHNITGLQTQGGGVFGTFVSSFYLQFSSDGRQWFTYKEMISDAR PKAKVFQGNSDDRGVALARLDRMVSARFVRILPHDFQNGIYLRVELMGCDDGAGCVSGQF SCPPPGGCVEAERRCDGVPHCPDGADERDCTHTNTTHTPPTAPPLRTPTARVTTTTEAGP GPRGDCSSALGLEDGRVHYGQLTSSSYRENNPADAGRLNIVPNVLVMEPGWSPLPGDPHP YFQVDFLEPTWISGVVTQGSERMWGYLTKYRLAFALTHTHFLNVTETGDRDSPPKIFEVR MVGRTPVTRWLDRLIRARFLRIIPVEFRPTFYLRVEVLGCRGDELVTASSEVSTAPPGGP GLQNHTGPTGRPGHYNYTSGPPGLHTRSPQDGSPGVAPHTHLTTAPPGVSTPRTGFWETS TAYDDGLPRVLCVEGQFSCRTFGCVEAVLVCDGHEDCPDGSDEHRCGPVTQRPLEPDRCS SKQFRCWSGECVSSDQRCDLHRDCADGSDENDCFDCVLSPWTSWSRCSVSCGLGSLFRQR NIVRDARPGGSCGGAQFDSRPCFIRACPVDGQWSDWTPWSDCGVSCGGGLMVRNRSCSNP PPKNGGRDCDGMSRQTHACNTHSCGTTTDAQSGCTGGMVLVKESDCLSGIMDACHVTCSD LHSDRNCTLNCTTGCYCPAGLFLQDGRCVDVSECECLWEGSLIQPGQEVRTSVCSSCVCK DGRVTCDESSCVARCDWSAWSSWTSCDSSCGTGIQHRYRSPLSPMGASRVDPCDGDSTEA RRCFTPCSDGPERVWSEWTLWSECSKTCFHHVDAVGLRRRFRSCNHTDTSATCGGEAEEH EPCNTLHCPVAGGWSSWWSWSSCSSECDSGVQTRERVCSSPAPLHQGLRCPGPHIQTRDC NVQPCSGVCPEGMTFLSKDQCVSQGGACPRVCMDATAEVECATECHDGCYCSPGFYLFNN TCVSLQRCPCYHKGALYSPGERVPHDDCNNCTCVDGVMHCGTAPCPVHCGWSEWTAWSAC SRSCDVGIRRRYRSGTNPAPAFGGRACEGERIGLDTCSVKPCFGVKGPWSPWSECSVPCG GGYRNRTRGPVRTHGTPQQFSACNLKPCGSGRACTNGQEWAVCVREELLCSDLGSDVQRD SSCHPGCQCPDGSALQDGECVPLPLCLCHVDGEQHKPGATVTKDCNNCTCESGKLVNCTS VECDVDGGWSSWTPWGVCSVSCGAGLQSRYRFCSDPERAGSGLPCVGSDREDRVCVSAPC SRDGGWSVWSSWTDCSKSCGGGVRSRRRDCDRPIRGGDGDYCEGLRTEVVTCNTDHCPVS SCSHVPGSVFSACGPSCPRSCDDLTLCEWRCEPGCYCTDGKVLSSDGSECVERDACPCLD LHTGRRVRPGESVQSPDGCNSCTCNGGKLSCGEHPCPVDGGWCEWADWTPCSKTCGQEWV SRYRSCACPEPRSGGAPCSDQQEEHNGLGVQIQRQPCPSVSFCPVHGSWGSWSSWSDCDV CVGVSVRLRVCNSPPARFGGLSCLGESRQTRGCHDNATVCSDCGAGQEEWACGKPCPRSC SDLHTHTECVDEPGCSRTCGCPGDTLMQDGVCVDRELCRCTFRNLSAAGINSGNVSWEWP GSSDWQQADPGETVTTDCQNCTCEAGVLQCDSAPGCSVDGSWSQWGRWTDCSAHCGGGVK SRSRQCDNPAPQSGGRECTGSGRQQKECNTHNCTDSGPWLDWSAWSSCSVSCGGGSQSRT RSCRTPPCSGMRRQSKTCNTHVCLEVGCPPGRLYRECEDGEGCPFSCSQVRGHEGCYSEG CEEGCHCPPNTFQHSGSCLHECPCLVDSDFLTALQSVSLTPELTPDLLNISVGSELASGE ELVHECSSCWCEHGVWNCSLAACPRDGGPSPWGPWGSCSLSCGGLGQKRRGRTCTRPSPA HGGRDCDGPLTDTAYCQTPDCPLVTVPTEEPSLPDEDAGMSPWSAWSPCSRSCSDPASPA VKSRRRECVQERCSGETRQERVCNLPQCPDGGVCQEAECVLRNCSWMQWGEWSSCSRSCG VGQQQRVRTFLAPGLNGTWCPDILGGNLEHRFCNIRACRVDGGWSRWSSWSRCDKACGGG RSIRTRSCSSPPPKNGGQKCSGEKNQVKPCNTKPCDDAGCPPGQEFVSCANECPQRCSDR QQGIECRTDAECEPGCRCPRGQLEQDGVCVQRWQCDCVDAWGQSWAAGSTHPLDCNNCTC ADGELHCTDHACADASSCSWSSWSTWASCSATCGPGRRTRFRSLVPEADGVSCQFEEVQH KVCDPGPCPPLCVRDQRQLAVGDSWLLGECEQCTCIPEGEYCQDIDCRVDGGWTPWSVWS DCPVTCGKSTQIRTRACINPPPRHNGTHCTGPERDTQDCHAALCLDDLCPWSPWSACSRS CGSGVMSRRRECVCEDDGDHACPPELERGGEETQLCYNRPCPACPMSEWSVWSECSCVSQ YQQRFRAPLVSASRGQNCRDLERQSRPCTPDHCHDCEKPFLFSECGSPCERQCDLLGQTH TCVSRQNCTAGCFCPEGLLHQNGSCVPQDQCGCVQLLHQDSDKPVAITVQQGALVTIGCT TCLCHAGSLQCDLQECEVMVSEWSEWTSCSPCIPASSAVPDLVSLQRRYRACLDVDSGRP ARGRESECGEALEEERICPQPDICTDLCHWSVWSAWSVCKDPCSGGYRQRERRPLTSDPG PHCRNLQTQSQSCNTGLCPGEHCEDRGRVFDSSCANQCPRSCADLWGHVQCLQGSCHPGC RCAEGRLLQDGVCVRVDECRCGAPVENGTLEIRPGDNITVSCNTCVCVNGSLACSDRVCP LYGPWGSWSVCSVSCGTGQRTRRRTCTHTPGGPACTETLQREICSRAPCPAGCVLSEWSS WSDCSASCGGGVSLRRKTVLQEPEPGGPTCSRPLEQHTACNTNNCLPDCPAGQVFSTCAG SCPYSCEDLWPENECVSVSCSPGCRCPPGAVMLNGSCVPQSQCPCSVLSLLSASPNVTLD PQEPEVPAGAVVPNLCNSCVCDGGLFICTNESCDVDCEWSVWSSWSSCSSSCGSGHQFSS RTVRRQHQYRGQECEGPSHTQRVCRGPECECPEGERWLWSVSGPERVCERGCVDLYRPEP LNCTGAGASEGCVCEEGRYRSLDGRCVIPALCPCEEDDGTIREPGLEWVDGCQSCRCING QKHCQSNCPPLQCSETDPLSRQPLRSEIESQIVLE NT seq 16128 nt NT seq  +upstreamnt  +downstreamnt atgagggttgtgctggtgtgtgttctggcgcttcatctggccggggtcatggggcactgg tgtgaacacacggtgcaggagacggtggagaggatgctgtccccccgtgagcagcgagag gtggactgttcctcggtttatcagtttaacacacagggctggaggctggacgtggaccgg atgcggcacgaacacggcggagacgacggcatcgccctttattacaagggacaggggtcc aaagcgtcctgttacatattcaaacctccagagattgagacggagacgctgaaccgcacg ctcagacagtgttgtgaaggctgggccggcccgcactgctctcatggagtgggtgcgcgg ggtcagtgcttctccacctggacgtgtgaggagttccccggggttggtaactcgtccctc atgacgctggagcagtgctgcggtcacctgtggggattgagctggaggaacgcatccgac cagacgtgtctgtcgtgcacatacacactcctgcccgacgtcaggtcttctccggtcatc cgtggcgtccgtgacccgcaggcgtccggcacctgtatgagctggggcgggacacactac cgtacctttgaccggaaacacttccacttccagggcagttgcacgtacctgttggcctcg tccaccgacgggacctgggccgtttactccagctcagtgtgtgacaccgcgggacactgt cgcaagggcctgcggatgatgttgggtctcggcttggtctctgttcacaaaggaaacatg acagtgaacggcgtgtctctaccgcagggtgaaccgctcttccaaaacggagtcagcgtt cactggctgggggactttgtgtttgtggagagcggtttgggcgtcagactgaagttcgac atggagaacaccgtctacctgaccgttaccgcagaacacctcacggccactagggggctt tgcggagtttacaacaacaacccagatgatgacttcactaccagcggtggaagtgtgtct cagtacgccgccagttttggaaactcctggcgtgtacaagatcagcaaggccaggtgtgt agtgatgctgctgagttgggccacagctgtgatctctcgagtgacgttagtcttcgccgt gacgcagaaacagcatgtcatcgtctgaaggaaaaccccttctcacactgccatcaccag gtggaccccgggccgtacatcgacacgtgtctgtatctgttctgcagtctggaggcgagc gagagagagacggcggtgtgcgatacgctagccggctacgtgcgcgagtgtgcgacgcaa cacgtcatcatccgctggagaaacgccggcttctgtgagcgtgtgtgtccgcgcggtcag gtgttctcggactgcgtgtcgtcctgtcctgcgagctgctcgtctcccggtcccgcggcg tcgggtcagtgtcgggacgagtgtgtgggggggtgtgagtgtcccccggggctggtcctg cacgcgggtcagtgtgtgcggcgggccgactgtccctgtttccaccggcgccgcacatac agcgcaggagacgccatcacacagaggtgcaacacatgtgtgtgtggagccggtcagtgg gagtgttctggagagagatgtgaagctcagtgcactgtgatcggagcgatgcacgtcaca acattcgaccagaagagattcagccttcagagcgcagactgccagttcacagccgtcgag gatttcgtggaccggaagttgagcgtgggcatcagcgcaggacagtgttcaggaggatct gctgggtgtctgagagagctgagagtcactgcgctgaagactacactcactgtcactgac tcaggctcagtgctggtgaacggtcagcgagagcttctgccggtggtcacaggagatctg atggtccgaaagtcttcctccagtgttctgctgatccaggcgttcggggctcgactgatg tggcatctggacgggcctctcctcctcatcaccctacagcccggcttcgctcataaggtt cgaggattgtgtggcactctgacctggagtcagcatgatgatttcaccacacccgagggg gacgtcgagaacagcgtgtcctcgtttgccgccaaattcagaacgggctcctgccctttg cccttagcgatgacctctgacccctgcgggatgtacacccagcggagacagtacgcagag agtgtgtgctctgtgattcacagctcagtgtttcaggcgtgtcatgacgtggtggaccga gagccgtacatgcgtgtgtgtctcagtgaagtgtgcggctgcgacccgctgaagtcgtgc caatgcaccgtcctcgccgcttacgcccgccagtgtgcccaggagggggcgccgctcagc tggaggaatcgcacattctgctcggtgcggtgctctggaggacaggtgtatcaggagtgc gggcgtccgtgcgggtcgtcctgtgccgatctgtggagcggctggagctgcgagggcgac gagggccgagggaactgtgtgccggggtgtcagtgtcccgccggactggcacaggacact cagggtcagtgtgtgcccgtccacatgtgtccctgcacacacggaggccagatctatccc gcggggagcaccagacagaacaactgcaacacctgtgtgtgtgcgcgtggcgtgtggaac tgcacagatctctcgtgtccggaggtccatcagtgtccaggatctctggtcttctctcct cggtcgtgtctgaggacgtgctccagtcccatctctcctctggacgcctgtgctgagccc atccacggctgtgtgtgtccggacgggacggtgctgctgggtgatcagtgtgtgaagcca gacgagtgtccatgtcatcacaacggcagactttatttcaccaatgacaccatttctaaa gactgcaacacatgtgtgtgtggcgagcagcgctggcactgcggtcaggcgttttgctcg ggaacctgcgtggccacgggcgaccctcactacatcacgtttgacgggcggcacttctcg ttcctgggcgactgcgagtacgtgctggcgcaggagtccagcgggctgttcagtgtgagc gcagagaatgtgccgtgcgggagcacaggggtcacctgcaccaaatctgtcacgctcacc gtcgggaacaccgccatacatctgctgagagggaaatccgtgacggtgaacgggattccc gtgactctcccgaaggtgtattcgggcagcgggctgatcctggagcgggtcgggctgttc gtgtccctctcgtctcggctcggagtctctctgctctgggacggaggcatgcgtgtttac gtgcggataactcctcatttgcgcggccgggttggaggattgtgtgggaatttcgacgga gacgcagagaacgacttcactacaagacaaggcatcatggagtcgaccccggaactgttc ggaaactcctggaagatcagcccttcgtgtcctgatgtcccagaccaggatctccgcgac ccctgcgctatcaaccctcaccgcgtgacgtgggccaagaagaagtgtgcggtgatcagc caggagatgttcggctcgtgtcactcagaggtgccgtaccagcagtactacgactggtgt gtctttgacgcctgcgggtgtgactctggcggcgactgcgagtgtttgtgtacggctgtg gctgcgtatgcggaggagtgtaaccgcagaggagtgtacgtgcgctggaggtcacaggaa ctctgcccgctgcagtgtgagaatgggctggtttacgaggcctgtggtcccgcctgttct ccagcgtgtcccagcactccttccctctctgattctctgtgccgaagcctctcctgtgtg gagggatgtttctgtcctcacggcactgttcggcacggtgaggtgtgtattcctccgtct cagtgtccgtgtgagtgggacgggtctttattcccggcaggagccgctgtcactcaacac tgtcagaactgctcttgctctgacggcgcgtggcgttgcgttgggtctccgtgtcctcct ccgtctccctgcgaggactcggagtttcgctgctcggctggatctcagcgctgtattccc tccgtctggctctgtgataacgaagacgactgtggagacggttctgatgaggtctgtccg ttcacgtgtccaccgggtcggttccgctgctccaccggagcctgtttaccgctggagctc aggtgtaacgggcatcccgactgcgctgaccaatcagacgaggacttctgtgagccgcac acggcagaacccggctgtcccgatggagagttcaggtgtgctaacgggcgctgtctgccg gtgaggaaagtctgtgatgggaggctggattgtggatttgctgatgattctgatgagtac gactgtggggccgtgtgccggccggacgagttcctctgttcctcgggccgatgtgttctg tatctgcaccgctgcgacggtcacgacgactgcggagactacagcgacgagagagagtgt gtgtgtgcgctcggagagctccagtgtcccggagatcagtgtgtgtccgcagagagagtg tgtgacggtcacagagactgtccgtccggcgtcgacgagctcatctgtccagtcaaaggt tgcagtcagtttgagttcgggtgtacgagtggccagtgtgtgccgatcgcgtggcgctgt gacggagagaccgactgcctggacgggagcgatgagaaaccgtgttcccgtacctgtcaa ccggaccagttcctctgccacagcggagaccagtgtgtccaacaccagcatctgtgtgac gggacgccccactgcagggacgcctcagacgagagcctggacaactgcggttccttacgg attcctccctgtctggacagtttctcgtgtgataatcgcacatgtgtgaacgtttcacgt gtgtgtaacggggttcccgactgccctaaaggagaggacgagatactctgcgataaagtc aggccctccacagcgccccctagtgagcgaaacaccagtcacgtctgtcctgagttcacc tgtgctgatgggtcctgcgttcccttcaacacgttgtgtaacggtgcagcagactgtgtg tcggacgggtccgatgagacgggctgtggtgtttggggcccctggagcccctggagcccg tgcagccgcagctgtggatccgggaccgtgagccggcagagacgctgccacccagaggat ccagacggacactgcagaggagagcaaacacaacgacagcagtgttactccaccgcctgc ccggtggatggctactggctgccgtgggtcacatggtcgaactgcagtcaaggttgtggt ggtgttgaggtccgccagagagagtgtttcccgccacagaacggaggccgaacctgcact gaactacctggagaaactcccctcaccgtcgacatcaaaccctgtcctcaagacggttgc gctaacgtctcgtgtccggcgggtctcgtcacacacacatgtgcgccgtgccctctgacc tgcgctcacgtatccggggcaacgacatgtgatcccaacgcagactgtttcacaggctgc tggtgtcctgatgggaaggtcatgaaccacgagcatcagtgtgttctgccggaggagtgt gtgtgtgaggtgtctggggttcggtactggccgggtcagcaggtcaaagtgggctgtgag atgtgtgtgtgtgagagaggtcgagcgcagcgctgtcagcccaacctagagtgctcagtt cactgcggctggtcgtcctggtccccgtggggcgagtgtttgggtccgtgtggagttcag agtgtgcagtggtccttccggagccccaataacccgtcacaacacggcagcggccggcag tgccgagggatctaccgcaaggcccggcgctgtcagacagagctgtgcagcgagtgtgaa tatggtggacacacacacacggttggcgagcgctggaaaggcgggcagtgccagctgtgt cagtgtttgcccaacttcaccgtgcagtgcggcccgtactgtccttatgctgccactgga tgcccacagggtcaaactctgatcccaggggaagaagacaagtgttgctattgtgaagag aaaggtgatatcaccaccgtcgtgacgccgacaccgatggtcctgcccataacggtggga ccctccacaccaccagagggccctccgactgtcccaacttaccccctgccccctggagac gagtgctggtcctctctgggcgtcccctcgctccccgactccagcttcagcgcctcgtcc catcagcccgaccaccctccgtccgcgggacgtctgcacgcccgagacccgcgcggggac ctgcagggctggagcccggagccgaaggagtaccgagagctgtcgaccgggacccctgag gagaccggaccctccaccggcccgttcctccagatcgacctgctccggcgccacaacatc acaggcttgcagactcagggcggcggcgtgttcggcacgtttgtgtccagcttttatctg cagttcagcagcgacggccggcagtggttcacgtataaagagatgatctcggacgccaga cccaaagcaaaggtgtttcagggcaacagcgatgaccgcggcgtagctctggcccgtctg gaccggatggtgtcggctcggttcgtgaggattcttcctcatgactttcagaacgggatc tatctgcgagtcgagctcatgggatgcgatgacggagcgggctgtgtgtcgggtcagttc tcctgtcctcctccaggggggtgtgtggaagcagagcgccgctgtgatggagtccctcac tgtcctgacggggcggatgagagagactgtacacacactaacaccacacacacacccccc acggcccccccgctcaggacgcccaccgccagagtgacgaccaccactgaagcaggacct gggccgagaggtgactgctcttctgctctgggattggaggatgggcgtgtccattatggt cagctgacctcgtcctcgtacagagagaataaccctgctgacgcgggccgtctcaacatc gtgcccaatgtgctggtgatggagccggggtggagtcctcttcctggagatcctcatccg tatttccaggtggatttcctggagcccacgtggatctccggtgtggtgacgcagggcagc gagcgcatgtggggttacctcaccaaatacaggctcgctttcgctctcacacacacccac ttcctcaacgtcactgagaccggagacagagactctcctcccaagatattcgaggtgagg atggtcggccggacgccggtcactcgctggttggacaggctgatcagagctcgcttcctc cggatcattcctgtagagtttcgtcccacgttctacctgcgtgtggaggtgctgggctgc agaggagatgagttggtcacagccagtagtgaagtgagcacagcgccacctggtggaccg ggattacaaaaccacacgggaccgacaggacgtcctggtcactataactacacatctgga cctccaggacttcacaccaggagtccacaggacgggagcccgggagtggctcctcacaca cacctgacaacagcgccacctggtgtcagcacaccgaggacagggttctgggaaacgtcc acagcgtatgatgatggtttacccagagtcctgtgcgtggaaggacagttctcctgcagg acgtttggttgtgttgaggctgtgctggtgtgtgacggacacgaggactgtcccgacggc tcagacgaacatcgctgtggcccggtcacacagcgccccctggagcccgaccgctgctcc tccaagcagttccgctgctggagcggcgagtgtgtgagttcagatcagagatgcgacctc caccgcgactgtgccgacggctcggatgagaacgactgcttcgactgtgttctgtctccc tggacgtcctggagtcggtgtagtgtatcatgtggactgggttcactcttccggcagagg aacatcgtgagagacgctcgacccggtggatcctgtggtggagctcagttcgacagccgg ccctgtttcatacgggcctgtccagtggacggtcagtggtcggactggacgccctggtcc gactgtggcgtgtcgtgtggcggaggactgatggtgaggaacaggtcctgctcgaaccct ccgcccaagaacggcggcagagactgtgacgggatgagcagacaaacacacgcgtgtaac acacactcctgcgggacaactacggacgcacagagcggttgcacaggaggaatggttctg gttaaagagtcggactgtttgtctgggatcatggatgcgtgtcatgtgacctgctctgac ctgcactccgacaggaactgcacattaaactgcactacaggatgttattgtcctgctgga ctcttcctacaagatggacgctgtgtcgacgtcagtgagtgtgagtgtttgtgggaaggt tcgctcatccagccgggacaggaagtcagaaccagcgtctgcagctcatgcgtgtgtaaa gatgggcgtgtcacatgtgatgagtccagctgtgtcgctcgctgtgattggtcggcctgg tcttcgtggacgtcatgtgacagcagctgtgggacgggaatccagcaccgttacagatct cctctgagtccgatgggagcgtcgagggtcgatccgtgtgacggcgactccaccgaagcc cgtcgatgtttcactccctgctcagacggccctgagcgagtgtggagcgagtggacgctg tggtccgagtgcagcaagacgtgtttccatcacgtggacgcggtgggactgagacgtcgc ttcaggagctgtaatcacaccgacactagcgccacctgtgggggagaagcggaagaacac gagccgtgcaacacactgcactgccccgttgccggtggctggtcgtcgtggtggagttgg tcgagctgttcttctgagtgtgattcaggagttcagactcgagagcgtgtgtgcagttct ccggctccgctgcaccaaggccttcgctgtcccggaccgcacatacagacccgagactgc aacgtccagccctgctctggtgtgtgtccggagggcatgacgttcctgtcgaaggatcag tgtgtgtctcagggcggcgcgtgtccgcgtgtgtgtatggacgccacggccgaagtggag tgtgccactgagtgtcatgatggatgttactgttctcccggcttctatctgttcaacaac acgtgtgtgtctctgcagcgctgcccgtgctaccacaagggggcgctgtacagtccgggg gagcgagtgcctcatgacgactgcaacaactgcacatgtgttgatggagtgatgcattgt gggacggcgccctgccctgtgcattgtgggtggagtgagtggacggcctggagcgcgtgc agtcggtcatgtgacgtgggcatcaggcggcgctatcgttcgggaaccaatccagcgcca gcttttggaggacgagcctgtgagggcgaacgcatcggactggacacatgcagcgtcaaa ccctgcttcggagtgaagggcccgtggagcccgtggtccgagtgttcggttccctgtggc ggcggatacaggaacagaaccagaggcccggtcaggactcacgggacgcctcagcagttc agcgcctgcaacctcaagccctgcgggagtggacgcgcttgtacgaatggccaggagtgg gccgtgtgtgtgagagaggagctgttgtgttcggatctgggctcggacgtccagagagat agcagctgccatcccggctgccagtgtcctgacggctctgccctacaggatggcgagtgt gtgcctctcccgctctgtctctgtcatgtagacggagagcagcacaaacccggagccacg gtcaccaaagactgcaacaactgcacatgtgaatcagggaagctggtgaactgtacgagt gtggagtgtgacgtggacggcggctggtcatcgtggactccgtggggtgtgtgttcggtg tcgtgtggcgctggtcttcagtcgcgctatcgcttctgttcggacccggagcgagctggg agcggccttccctgcgtcggctcggaccgagaggacagagtgtgtgtgtcggcgccctgc agcagagacggaggctggagtgtgtggtcgtcctggaccgactgcagtaagtcgtgtggg gggggcgtgaggagccgcaggcgggactgtgatcggccaatcagaggaggagatggagac tattgcgaaggactgagaactgaagtcgtcacgtgtaacacagaccattgtccagtgtct tcatgttcacacgtgccaggaagtgtgttcagcgcctgtggaccctcgtgcccgagatca tgtgacgacctcactttgtgtgagtggcgctgtgagccggggtgttactgcacggatggt aaagtcctgagttctgacgggtcggagtgtgtggagagagacgcgtgtccctgtctggac cttcacaccggacgacgagtccgacccggagagagtgtgcagtctccagacggatgcaac agctgcacctgtaacggagggaaactctcctgcggtgaacatccgtgtccagtggacggc ggctggtgcgagtgggccgactggacgccgtgttcgaagacctgcgggcaggagtgggtg tcccgttacaggagctgcgcctgtcctgaacccagatcaggaggagcgccgtgttcagac cagcaggaggagcacaacggactgggagtccagatccagagacagccgtgcccgtccgtg tccttctgccccgtccacgggtcctggggctcctggagctcgtggtcggactgtgacgtg tgtgtcggtgtgtcggtccggctcagggtgtgtaacagtcctccggctcggttcggcggt ctgtcgtgtctcggagagagtcgtcagacccgcggttgccatgacaacgccaccgtctgt tctgactgcggcgctggacaggaggagtgggcctgtgggaagccctgtcctcgctcctgc tcagatctgcacacacacacggagtgtgtggacgagccgggctgcagtcggacctgtggc tgtcccggagacacgctgatgcaggacggggtgtgtgtggaccgagagctgtgccgctgc acgtttcgcaacctcagcgcagcgggaataaactctgggaatgtttcctgggaatggccg ggatcgtcggactggcagcaagcagacccaggagagaccgtcaccaccgactgtcagaac tgtacatgtgaagccggtgtgctgcagtgtgactccgctcctggatgctccgtcgacggc agctggagccaatggggtcgctggacagattgctccgcccactgtggaggcggggtcaag tcgcgctcccgtcagtgtgataaccccgcccctcagagcggcggcagagagtgtacgggc tccggccgacagcagaaagagtgcaacactcacaactgcacagattcgggcccgtggttg gactggtcggcgtggtcctcgtgctcggtcagctgtggcggaggctctcagagtcgaacc cgctcctgccggacgcccccctgctccgggatgaggcgccagagcaagacctgcaacaca cacgtgtgtctggaggtgggctgtccccctggccgtctctacagggagtgtgaggacggg gaaggctgtccgttcagctgttctcaggtcagaggtcacgagggctgttactcggagggc tgtgaggagggctgccactgtccacccaacaccttccagcacagcggctcctgtctgcac gaatgtccatgtctggtggactcagacttcctgaccgctttacagagtgtatcgttgacc cctgagttgacccctgacctcctgaacatcagcgtggggtcagagctggcgtcgggagag gaactggtgcatgagtgcagctcctgctggtgtgaacacggcgtgtggaactgctctctg gcggcctgtccccgtgatggcggcccgtccccgtggggcccctgggggtcctgctcgctc agctgcgggggtctcggccagaagcggcgcggcaggacctgcacccggcccagtcctgct cacgggggccgagactgtgacggacccctgacggacaccgcgtactgccagacgcccgac tgcccgctggtcacagttccgacagaggagccatctttaccagatgaggacgctgggatg tcgccgtggagcgcgtggagtccgtgttcccgatcctgcagcgatccggcttctccggct gtgaagtcccgcaggagagagtgtgttcaggagcgctgctctggagagactcggcaggag agagtgtgtaatctgcctcagtgtcccgatggaggtgtgtgtcaggaggccgagtgtgtg ctcaggaactgctcctggatgcagtggggcgagtggagctcctgctctcggtcctgtggc gtgggtcagcagcagcgggtcagaaccttcctcgccccgggcctcaacgggacctggtgt ccggacatcctcggcgggaacctggagcaccgcttctgtaatatccgggcctgccgcgtg gacgggggctggtcccgctggagctcgtggtctcgctgtgataaggcgtgtggcggagga cgctccatcaggacccgctcgtgctccagtcctccgccgaagaacgggggccagaagtgc agcggagagaagaaccaggtcaagccctgcaacaccaaaccctgcgatgatgccggctgt cctccagggcaggagtttgtgtcgtgtgcgaacgagtgtcctcagcgctgctccgaccga cagcagggcatcgagtgccggaccgacgccgagtgtgagccgggctgccgctgcccacga ggccagctggagcaggacggtgtgtgtgttcagcggtggcagtgtgactgcgtggacgcg tggggtcagagctgggcggcgggcagcacacacccgctggactgtaataactgcacctgc gcagacggagagctgcactgcactgatcacgcctgcgcagacgccagcagctgcagctgg agctcctggtccacctgggcgtcctgcagcgccacctgcggcccggggcggaggacacgc ttcagatctctggtcccggaggctgacggcgtgagctgccagttcgaggaggtccagcac aaggtgtgtgacccgggcccgtgtcctccgctgtgtgtgcgggaccagcgccagctggcg gtcggagactcctggttactgggcgagtgtgagcaatgcacctgcatccctgaaggagaa tactgccaagatatcgactgtcgagtggacggtggatggacgccgtggtccgtgtggtcg gactgtcccgtgacgtgtgggaagagtacacagatccgcacccgcgcctgtatcaaccct ccgccgcgacacaacggcacacactgcactggacctgagagagacacccaggactgtcac gctgcactgtgtcttgacgacctttgcccctggtccccgtggtcggcctgttcgcgcagc tgcgggtcaggcgtgatgtccaggcgccgggagtgtgtgtgtgaggacgacggggatcac gcgtgtcctccggagctggagaggggcggcgaggagactcagctgtgttataacagaccc tgtccagcctgtccgatgtcagaatggagtgtgtggagcgagtgttcgtgtgtgtctcag tatcagcagaggtttcgtgcgccgctcgtgtcggccagtagagggcagaactgcagagat ctggagcgccagagccgaccctgcacaccggaccactgccacgattgtgagaagccgttc ctgttctctgaatgtggatctccctgtgagagacagtgtgatctgttgggtcaaacacac acgtgtgtgtcccgtcagaactgcacagccggctgcttctgtcccgagggtctcctgcat cagaacgggtcgtgtgttcctcaggatcagtgtggatgtgttcagcttcttcatcaggac tcagacaaacctgtggccatcactgtccagcagggggcgctggtgaccatcggctgcact acatgtctttgccacgccggctctcttcagtgtgatttacaggaatgtgaagtgatggtc agcgagtggtcagaatggacctcttgctctccgtgtatcccagcatcctctgctgtcccc gatctggtgtcgctccagagacggtaccgggcctgtctggatgtggactctgggcgtccg gcccgcgggagagagagcgagtgtggcgaggcgctcgaggaagagaggatctgtccacag cctgacatttgcaccgatctgtgtcactggagtgtgtggagcgcgtggagtgtgtgtaaa gacccctgcagtggcggataccggcagcgggagcgccgacctctgacctctgaccccgga ccgcactgcaggaacctgcagacacagtctcagagctgcaacacaggcctctgtcctggt gagcattgtgaggacagagggcgtgtctttgactcctcctgtgccaatcagtgtccccgc agctgcgctgacctttggggtcacgtccagtgtctgcagggctcctgtcatccagggtgt cggtgtgcagagggccggctgttgcaggacggagtgtgtgtgcgcgtggacgagtgtcgc tgtggggctccagtggagaacgggacgctagagatccggcccggagacaacatcaccgtc agctgcaacacctgtgtgtgtgtcaacggctctctggcgtgttctgaccgggtgtgtccg ctctacggcccgtggggatcgtggagtgtgtgttcggtctcgtgtgggacggggcagagg acacgccgacggacctgcacacacacacctggaggaccggcgtgcactgagacccttcag agggaaatctgctctcgggcgccctgtccagccggttgtgtgttgagcgagtggtcgtcc tggagcgactgcagcgcctcctgtggcggaggagtgtcactgcgcaggaagaccgtcctt caggaaccagaaccagggggtccgacctgctcccgacccctcgaacaacacaccgcgtgc aacactaacaactgcctgcctgattgtcccgctggtcaggtgttcagcacatgtgccggg tcgtgtccgtacagctgtgaggatctgtggccggagaacgagtgtgtgtcggtgtcctgc agtcctgggtgccgttgcccgcctggagccgtgatgctcaacggaagctgcgttcctcaa tcccagtgtccttgctccgtcctctcgctcctgtcggcgtctcccaacgtcacccttgac ccccaggagccggaggtccccgccggagccgtcgtcccaaacctgtgcaactcatgtgtt tgtgacggcggactctttatctgcactaacgagtcatgtgacgtggactgtgagtggagc gtgtggtcctcgtggagctcttgttcctcgtcctgcggttctggacatcagttctccagc cggaccgtacgccgacaacaccagtacagaggacaggagtgtgagggcccgtcacacaca cagcgagtctgcaggggccccgaatgtgagtgtcctgagggcgagcgctggctctggagt gtgtccgggcccgagcgagtgtgtgagagggggtgtgtggacctctacaggccggagccg ctcaactgcaccggcgccggggcctcggaggggtgtgtgtgtgaggagggccgctaccgg agcctggacggccgctgtgtgattccagcgctctgtccgtgtgaagaagacgacgggacg attcgagagccggggttggagtgggttgacggctgtcagtcgtgtcgctgtatcaatggc cagaaacactgtcaatcaaactgtcctccactgcagtgctctgagactgacccgttgtcc aggcaaccgctccggtccgagatcgagtcccagattgttctggagtga

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