Pimephales promelas (fathead minnow): 120472327
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Entry
120472327 CDS
T08155
Symbol
arhgef12b
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
pprm
Pimephales promelas (fathead minnow)
Pathway
pprm04270
Vascular smooth muscle contraction
pprm04625
C-type lectin receptor signaling pathway
pprm04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
pprm00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
120472327 (arhgef12b)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
120472327 (arhgef12b)
09153 Circulatory system
04270 Vascular smooth muscle contraction
120472327 (arhgef12b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pprm04131
]
120472327 (arhgef12b)
Membrane trafficking [BR:
pprm04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
120472327 (arhgef12b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
APAF1_C
Motif
Other DBs
NCBI-GeneID:
120472327
NCBI-ProteinID:
XP_039518404
LinkDB
All DBs
Position
Unknown
AA seq
1499 aa
AA seq
DB search
MSGTQSTLAERFPKKASRTGSILIKDHPPDKKPKSDKASVPPSHEFDPTELPIQSVVADG
RPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIKVNGTL
VTHSNHVEVVKLIKSGSYVALTVLGRPPGLPQIPLSDGEVEEGSLFSLTSPHSPGPIGPD
RSSSSPSPSERKPTPLPVWAMTEEYSRNPTPKLLKENQDAKKHIPQHQEQLSKPTGTGQD
GSISPRPGEGEQEDGGGDLDRPPSWQGDAGTEPLWTNNITTPVTPSPFLESPCQRETPCH
SPKTTPRDSLNSCPSPDAEDTPDLDSQSSMGSPSSRPVAHIIGAEDEDFDTEQEQMNGQC
SCFQSIDLLKSRPAHLAAFIHHVVSQFDPAPLLCYLYAELYKQTSSKETRRILMDTFFID
KTASLKVTVPESIITDLERTAHSINAERKRPEPISEDVHRQYVQQLQDTLLPDIQKNLED
FRQKRSMGLTLAEAELARLDTERMRDRVAPEKERACAEHIISKIEDVLLTSQATEEDKCT
TMQFVILSYMKQLGVKVKESRGLEHKPKLMNLFPKIKKSIKPEKDGSEEKSKKTRFPNVF
PQRRPSRVDPSLRQREALEPRQRMTKPQLPLGTGEQTDGSSLPIRVSQSSEGSDGSTALV
TSPPYSAPAAPDGISRESETGGLPLSAQARMGEGSIPGDSQDSSSSNTHFDFSPCTLEHL
QEEEAETDKTLDTGTPRPDRSRTDPLGSGEVQSEDDQCVEVELEPSNWQTLVSRDVLSTL
TPQEIKRQEVINELFYTERAHVRMMKVLENLFYQPLIRDSILPSADIKSIFSNLEEIVHL
HMSLTEQMAAVRKKNETALIDLLGDDLLSWFSGEEEAKIKRAAGTYCSNQPFALELIKSK
QKKDQRFNSFIQEAESNRNCRRLQLKDIIPVETQRLTKYPLLLENIAKYTEDPEERSKVK
RAGECCRKILTHVNQEVKEAENKQRLEDYQRRLDLSSLKQSENPMIAEFKILDLTKRKMV
HEGPLSWKVNKDKTIELYTLLLEDILVLLQRQDEKLILKCHSKNLAGTAETKHIFSPIIK
LSTVMVRSVATDNRSFFVLSMSDNGAQIYELMAQTVSEQKTWQCLITQSADSMKTKLPNI
IPLPQTDGEREEVELINSGVPKLNKDAEPISLGSIQSPEKDDTEVMSTEVMSTEVISTPP
SSTNPFETKSDEEDEEEENLVPDQAEDDEAFVVADMTDRLTLLKQRSRLGIAIDEDEAEA
FELQPLRADEALRTLATLRQLLINHMSSQEDTDRDPERGEQREHVARTGSQQGPENSAVI
GSTVENGSERGENRGENAQELPSGDTGFFETSEDCVSAGSYMVLEVYGGSGESSTDDDVQ
ANSGEPVAGGDSGIDLKKLLSSSSQSSGGPNVNRQIMTHIRLLQANLQHLKDTEIKYNQL
RQRLSEETATDTEENKGGDTETLGFSSPAPLETMFMHETESQQDDPNPSLQISAHAMVL
NT seq
4500 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcacacagtccacgcttgctgagaggtttcccaaaaaagcgagcaggacagga
agtattctcatcaaggaccatcccccagacaaaaagcccaaaagcgacaaggcgtcagtc
cccccctcgcatgagtttgaccccacagaactgcctattcagagtgtagtagccgacgga
aggccagagtcttgcgggcttgtgcagcgttgtgtcatcatccagaaagatgagaatggc
tttgggctgacagtgagcggcgataaccctgtgtttgtacagcttgtaaaagaggatgga
gctgccatgcgagctggtgttcagacaggcgaccggatcataaaggtcaatgggacatta
gttacacattcaaatcatgtagaagttgtaaagctaataaaatcgggctcctatgtggcc
ctgaccgtgctggggagaccgccaggcctgcctcagatccctctctcagacggcgaggtg
gaggaggggtctctcttctcgctcacttcccctcactccccggggcccatcggtccagac
cgctcctcttcttcccccagcccctcggagcgcaaacccacccctctgcctgtatgggcc
atgacagaggagtacagcaggaaccctacacctaaactactgaaggaaaaccaggacgcc
aagaagcacattccacagcaccaggagcagctcagcaagcccactgggactggacaggat
ggctccatatctccaaggccaggtgaaggcgagcaggaggatggagggggagatttggat
cgacccccttcctggcagggtgatgctggaacggagccattgtggaccaacaatatcacg
acccctgtcacgcctagtcctttcctggagagcccatgccaaagagagaccccctgccac
agtccaaagaccacaccccgagacagcctcaactcctgtccttcaccggatgccgaagac
acacctgatcttgattctcagtcgagtatggggagcccctcctctcgtccggttgcgcac
attattggtgctgaggatgaagactttgacacagagcaggaacagatgaatggccagtgt
agctgttttcagagcatagacctcctgaaatcccggcctgctcacctagcagcttttatc
catcatgtggtctctcagtttgaccctgcgcctctgctgtgctacctctatgctgaactt
tacaaacagaccagctccaaagagacacgacgaatcctcatggataccttcttcatagac
aaaacagctagcttgaaagtaacagtacctgaatccatcatcactgacctggagcggact
gcacactcaattaatgcagaacggaagaggccggagcccatctcagaggatgtccaccga
cagtacgtgcagcagctgcaggacacacttctacctgacattcagaagaacctagaagac
ttcaggcaaaagcgcagtatgggtctgacgctggctgaagcggaactagcccgtctggat
acggagagaatgagagaccgggtggctcccgaaaaagaacgagcctgtgcagagcacatc
atctctaagatagaggatgtactactgacgtcgcaggccacagaggaagataagtgtacc
accatgcagtttgtcatattgtcatatatgaagcagctcggcgtaaaagtgaaggagtct
cgagggctggagcacaagcccaagctaatgaatcttttccctaagataaagaaaagtata
aagcctgagaaagatggaagtgaggagaaatcaaagaaaacacggtttcctaacgttttt
cctcagagacggccgagcagggttgatccttcactcagacagagagaggctctggagccg
aggcagcgtatgacaaagcctcagctgccgttgggcactggagagcagacagacgggtcg
tctcttcccatacgggtcagtcagtctagtgagggctcagatggcagcactgccttggtc
acatcacctccttacagcgctccagcagctccagacggcatcagccgagagtctgaaact
ggtggacttcctttatctgcacaggccagaatgggagagggttccatcccaggagattcg
caggactcctcctcttcaaacactcactttgacttcagcccctgcacactggagcatcta
caggaagaggaagctgagacagacaagacgctggacaccggcactcctaggcctgaccgg
agcaggacggatccgctgggctctggagaagtgcagagtgaggatgatcagtgtgttgag
gtggagctggagccttctaactggcagacactggtgagcagagacgtcctgtccacactt
acccctcaggaaatcaagagacaagaagtcatcaacgagctgttctacactgagagagca
cacgttcggatgatgaaggtcctggagaatttgttttaccagccgctgatcagagactcc
atcctgccttctgcagacatcaaaagcatcttcagcaaccttgaggagatcgttcatctg
cacatgtctctaacggaacagatggccgctgttcggaagaagaatgagacggcgctcatt
gacttgttaggagacgatttgctttcctggttcagtggggaagaagaggcgaagatcaag
agagctgcgggcacgtactgcagtaatcagcctttcgccctggaactcatcaagagcaaa
cagaagaaagaccagcgcttcaactccttcattcaggaggcggagagtaaccgtaattgt
cgcaggctgcagttaaaggacatcattcctgtggagactcagagactcacaaagtatccc
cttctgctagagaacatcgccaaatacacagaggaccctgaggagagaagtaaagtgaaa
cgggctggcgaatgctgtcgaaagattctcacccacgtcaatcaggaggtgaaagaagcc
gagaacaaacagaggttggaggactaccagagacgactggacctgtcctcactgaaacag
agcgagaaccccatgatagcagagtttaagatcttggacttgacgaagaggaagatggtg
catgagggaccactatcctggaaggtcaacaaagataaaactattgagctgtacacattg
ctgctggaagatatattggtgctacttcagaggcaagatgagaagctgatcttaaaatgc
cacagtaagaatctggcgggcaccgctgagaccaaacacatcttcagccctatcatcaaa
ctcagcactgtcatggtgcgctcggtcgccaccgacaacaggtcattctttgtactgtcg
atgtctgataatggagcccagatctatgagcttatggcccagactgtatctgagcagaag
acgtggcagtgtttgatcacacaaagtgcagacagcatgaagaccaaactaccaaacatc
attccattacctcagactgatggggagcgtgaagaggtcgagttgatcaactctggtgtt
ccgaaactaaacaaagacgctgagcccatttctttagggagcattcagtctccagaaaaa
gatgacactgaggtcatgtctactgaggtcatgtccactgaggtcatttcaaccccgcca
tctagtaccaacccgtttgagaccaaatctgatgaggaggatgaagaggaagaaaacttg
gtaccggatcaggctgaagatgatgaagcgttcgtggtggctgatatgaccgatcgactg
acattactgaagcagcgctcgagactgggcatcgccatagatgaggacgaggccgaggcc
tttgagctccagccactcagagctgatgaagctctcaggacactggcgacactgaggcag
ctcctgatcaaccacatgtccagtcaggaggacacagacagagaccccgagagaggagag
caacgggagcacgtggcgaggacgggttctcagcaggggccggagaacagcgctgtgatc
gggtccactgttgagaatggctcagagaggggcgagaacagaggggagaacgcacaggaa
ctgccctccggagacacgggcttctttgagacgtctgaggattgtgtctctgcaggcagt
tacatggtgctggaggtgtatggaggctcaggtgagagcagcacagatgatgacgtgcag
gccaacagcggggagccagtggctgggggagactcaggcatcgacttgaagaagctcctc
tcatcctcctctcagagcagcggaggacctaacgtcaacagacagatcatgacccacata
cgtctactacaggccaacctgcagcacctgaaggatacagaaatcaagtataaccagcta
cgccaaaggctatcagaggaaacagctactgacacagaggaaaacaaaggaggagacaca
gagacactgggcttctccagccctgctcctcttgaaacaatgttcatgcacgagacagaa
tcgcaacaggacgaccccaatccctcgctccaaatctccgcgcacgccatggtactttga
DBGET
integrated database retrieval system
