KEGG   Pimephales promelas (fathead minnow): 120475849
Entry
120475849         CDS       T08155                                 
Symbol
kmt2ca
Name
(RefSeq) histone-lysine N-methyltransferase 2C isoform X1
  KO
K09188  [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
Organism
pprm  Pimephales promelas (fathead minnow)
Pathway
pprm00310  Lysine degradation
pprm01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:pprm00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    120475849 (kmt2ca)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pprm03036]
    120475849 (kmt2ca)
Enzymes [BR:pprm01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     120475849 (kmt2ca)
Chromosome and associated proteins [BR:pprm03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     120475849 (kmt2ca)
   HMT complexes
    MLL3/MLL4 complex
     120475849 (kmt2ca)
SSDB
Motif
Pfam: PHD FYRC SET FYRN zf-HC5HC2H zf-HC5HC2H_2 HMG_box PHD_NSD PHDvar_NSD
Other DBs
NCBI-GeneID: 120475849
NCBI-ProteinID: XP_039522553
LinkDB
Position
Unknown
AA seq 4942 aa
MSSEDKSLDLSEQGPSPPLSSAGATPSGSPAPSDRRPRGRPRKDANSVALTTQSKRKFRS
RGCAQADDEDSMDASDVTPTPDIDITPEMDVLEPDTDDDYFPEPLDLSPRDERPLSPLFQ
RSVSEDSAGSSASTTRKAKTREKLCAFCYCGEKSLLGQGELKLFGPTPGYVPLHIRNRRG
SSEKDDDYHDDDNDFDDNRSPGHRGRGLKKVSSPDSGLHSTSAPGSTDPAAEEPSRKFWD
ELGQIGLPDDINVSSLFDPTGQCCAHLRCAAWSEGVCRGEGQSLLYVDKAIDSGSTECCA
YCKRLGASIKCCEESCGRSFHYPCAAAAGTFQNIKTYTLLCPDHIQQALIRSKDEVNCLV
CDSSGDLLDQLFCCTCGQHYHGACLDITVTPLKRAGWQCPECKVCLACKNPGEDSKMLVC
DMCDKGYHTFCLQPIVDTIPTNGWRCKNCRACAQCGTRPNGQWSSNGVMCEGCQQQHDST
QLCFICGQNQDSGSPADKHSCCACKRWVHVDCGRQEGADPNNEVQDGYTCRVCKQVQEES
GHNQPISSQEPSLSDPEPIEDVFMAVEVNEAKGEVALETELRTSPLPTQPEEFLSSAEPP
QEIQVTVTLTEGPEPPPCSSTLVGVPSLSFQASTNSEDQNQEQTLIGALEMGKETEDKLS
EATEDEPEADVSKALPALPTKETSPKLSRAQEEDPMIVCPSDTSNMKDKMMTNVPEAQSV
VEEIEQGQKQDRPELEEKEVLDPEVSCILPEPGSVPLVAECSPTVEMDTTPVSEHSFSSF
SSPIEDKSLVLKHSPAMSSEGSTKLTQSPFSTEASPREISQSQTPTHSLNPAPYSPSVFN
TTFFPLTPKIGMGKPAISKRKFSPGRPRVKQGAWSNRSAMSSPSWSPERLEAWDSPKTRP
MHGLPTWTMRLGRGSGFPGRRRPRGTNLSGRGGRGRSRLKMESSPVVTPGVSFMDSPYVV
KEEEENSMHNTVVMFSTSDSFTLKQDMCVVCGSFGQGAEGRLLACSQCGQCYHPFCVNIK
ITKVVLSKGWRCLECTVCEACGQASDPGRLLLCDDCDISYHTYCLDPPLQNVPKGSWKCK
WCVLCTQCGATSPGLRCDWQNNYTQCGPCASLTVCPVCARNYREEELILQCRQCDRWVHA
SCQGLNSDEEVENAADEGFDCSLCRMHTMPTSGGTVAKLMDISEPPLVTQILAKVKENEF
QRTYTKDGVCLTESGLCQLQSLCVPAARRRRPKPKLKLKIINQNSVAVLQTPPDPQSELF
RDGDMDDSREGDPMDCDGKSDSSPEREPCDDHLKGVDGNKKRKRKPYRPGIGGFMVRQRS
KAGQGKGKRSLSQKDSASSLTENLTEKEQGWNEPDTPIVSEPLEKVKKRYRKKKTKLEEV
FPSYLQEAFFGKELLVKSKKTKSTLETGLVEEEANHTDSKSQTRSFLDPLSDPLLSTTST
PVSSKAGQLPNVEDPLAELVLHSDDDLLGMLSDDLVKPGPESGLDLCPFQVDRSPSPFAG
LNIGALPDDQSTSPHPGSSRGSRTIQEEPLDVILSPELDKMVSDGAILSKFYKIPELEGK
DVEDLFTAVLSPSANQPPQLTHSSNTAPNASATAMSVQNPGNAGGMFPRLPMMNGMMGPN
THIIPNPMIAEAGVSGTFSSIHRMPFSENMTEKKFSQIGGDVIGPWASPAPVLGSVPPPE
VETDTMSNAQRSTLKWEKEETLGEMATVAPVLYTNMNFPNLPDEFPDWATRVKQIAKLWR
KASSQERAPYVQKARDNRAALRINKVQMSNDTMKRQQQQQQQQPVDPFDPSIPIDTELLF
KDPLKHKESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQLQKQQQQQQFSGDT
SESGSQSPVTTQTSSGNTSPLQELTSKDGFQMLETVTSGTSTDDVFLRPQPPPPSSTAKT
PTQDTQYMQGPSSQPQSPQMFSPESSGSRPSSPWDPYGKMVGTPRPPPSGLSAPRRGSLS
DVQDRNRPSPAHESTDPYAKPPDTPRPSDPFVKPMCPPRPGPLTEQQGRNCISNVMPGDN
FSRPGQRSEVYQRMAHSRMVLSDPYSRPLLTPIPGSNESGSVPVFKTPMPPSQFQQDSFS
AGQQGMRRGSSDAFSQIQHSDPYSHKPLTPHPSMGDGFSNEGRMMHPGPGGPFAQPLPMG
RHPQRDPYSQAPSTPRPDYPQQMPDPYAQPPGTPRPHDPYAQMPGTPRPHSDPYPLLPST
PRTVTIDPFSQSQPNSRRQSPSHAIDPYAQMPGTPRPFPGERYPKSPGSQRSSDPFLQPP
GTPRPVKNETCDQSPGTPRPVLPDPYCQPPGTPRPGAGPEAFSRPNPRLNFVAHQTDPLG
HQAQSRIQDPFARPCALDSQTPKHPAISDESLSLQQTNPNKTPIHDPFEQASLTPCSQAG
ERLSHDVSVNTGNPSDSQNTMQPPLGETEEKIKQRQRLRQLILRQQQQKSAIRLEKGLQE
ATATAAPGTPRHWSQDDSGPQKDIFGRPPPPYPGTMRSSAINAGQRFPGTFLADQHGSMS
DEPQCSRPPLPRDVNNMRPQGQRFGFPPGAPNQEQFIRPPHQIQGGPMLDNIPPHMRRPL
SVDIARQIGSNHQMGLPQHFPPRGLSMQQHNIMGQPFIELCHRAPENRVRLPFGPPNALD
HPNHPQRPPHGFMGGQNMAFTGNQGPRIMDQMLGLSHQGSVSHMQTSTNMDNLHHHTNTV
PQQTTVAVPLRHLVSRDSVTPSESALLPVTTSGPTEEIPLPCSDGVVDKLETDDSAVKDL
DDVEVKDLVDEDLDNLNLDADDGKDLDDLLESGKFDLIAYADPENLGDKKDMFNEELDLS
DHIEDDHGDTSDLQKALSEKRNSRCEGVSSAQPKPEAIQGPSNVKLEKSLSKEFLDSQSE
RTMKTESQGFGNSVDDHQPMSSKSGQDDVSVLFEESSAHGHPGSAPVLSSLLIKEKLGET
RSESIISPISADPDAQTNLGSNMSMVMLRGQPEDHGINPGVAMGHRVDPPLTQGPILGNP
NLMQSENQQVPNLGFGASQGQQVDLNLPIVSAQQPVPHSLNLQTQQGMFNPGATGQQGSQ
VQQNQHNRPLLLDEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSNDPFFPNIDFDAITDP
IMKAKMVALKGINKVMVQNSMGMTPIVMNRVQQIPGSHAPDTAGFSQHFLDGKLPPQIAR
PNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKFLEDQIGAHRKSKKALSAKQRTAKK
AGREFPEEDAEQLKHVTEQQSVVQKQLEQIRKQQKEHAELIEEYRVKQQQQQQRLQPAVM
GPIKAMPGMQGQPPPVMPGGPPMGQPMLGPMLPMQQPHFGKPTRMSNVPRWHPGTTGPMP
GPRMPPHLPPQMPLPNPSQPLQTQPPSPMVPGGKPGQPGTVAGGNGGGASNSSSAPHVKF
DDNNPFSEGFQERERRERLREQQEKQRVQLMQEVERQRALQRLELEQQGLGLGPNNSGDG
LTQMPFYNSDLSQEFMQTPRNKQQPQQIGPVFPQQGNTPLDFVNPGFLQGGERRPMPGNG
SFGPDISSNFQPKNPMMHGFTPGQPRLPGFGGLGMPPHGGGETSSFGVESTTSLPPNFPG
AGQSLIQLYSNIIPEEKGKKKRSRKKKRDDDADSVKTPSTPHSDITAPLTPCVSDTSSTP
TRSVAIMGDQDALDQDPLSGGTPLGRQSSVGSEAERGLLCDIKLEKLEASVCQRGEGEAM
FGHSAGGTGIVKTEEGNEIISPSPASKSPVQSTKGDTGNELLKHLLKNKSTPPPSSTPLI
HQMSNDSIQSEEEGLNDSKGSLRLDSTDSLSGINSQTGNPDLEPLVPDQSKRKQRNKRTP
KNGAEKPPSRWKKRKKDDEERQAVYTNTDTLMTQLKQQLSMLPLMEPLIRVNFAHFPLYG
SGQLNGENRLSGSFGNASLDGVSDYYSQLIYKQNNLSNPPTPPASLPPTPPPVARQKLLN
GFATAEELAKKAEIMVSKSLGQKQLKAPFKAEDDLLGHTITQGPKTVDVPASLPTPPHNN
QEELRGQEHCVDRDTPDSFVPSSSPESVVGMEISRYPDLSRVKEEPPSPAVSPVIPILDG
NGSEARQWEVKAEPPSNFFASQFGQHLRTDLVSVSVTLNPVATHNIPGVVSALANMLCVS
IPRNYEVIRSPGQEHRSSMDMFSELRVPPQTALYHQQPGMRLLRPPGAPLPHQTFIEGSV
VVRPDYPMGGSSPGPKPQWCSHCRVVILGNGVRKSTKDLPINKQGHGGSEGSLVFCSHNC
FVLYSASMQNKLLDGKPNVLPPSDSEDKHNPTKVFHQYSHNMSDLDVHCLAQLQPKQSPP
PTQIISFPSITSETLRGDSKSDTLKVTVKLKPRPRAVHNGVDDPRCSFGKRWKALRWRKW
SVQIVVPKGNYHLPGEEEVDELLKKLGTSLRPEPMPKDLRRCCFCHEEGDGLTDGPARLL
NLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLSVRCTYCQQIGATSGCHRLRCT
NAYHFTCALKAQCTFFKDKTMLCHLHRPRGTGSMGGGLAGTEHELRCFAVFRRVYVQRDE
ARQIASIIQRGEREHTFRVGSLVFHSVGQLLPHQMQNFHSMSAIFPVGYKASRIYWSMRH
GNRRCHYVCSIDEKDCDPEFIIRVVEQGYDDLVLTGSSPKGVWDKVLEPVAERRNEAGSL
KLFPVYLKGEDLFGLTVSAVTRVVESLPGVEACEQYTFRYGRNPLMQLPLAINPSGCARS
EPKACTHVKRFVLRPHTLTSSSFSKALASSGNPAEMGVAPYSKHFVHSKSFQYRRMKAEW
KSNVYLARSRIQGLGLYAARDIEKYTMVMEYIGTIIRNEVANRKEKMYEAQNRGVYMFRI
DSEHVIDATITGGPARYINHSCAPNCIAEAVTFERDHKIIITSNRRIQRGEELCYDYKFD
LEDDQHKIPCHCGAVNCRKWMN
NT seq 14829 nt   +upstreamnt  +downstreamnt
atgtcatcagaggataaaagtctggatctctctgagcaaggaccatctcctcccctgagc
agtgctggggccacgccctcagggagcccggccccctcagatagacgcccacggggccgg
ccacgcaaggatgctaactctgtcgcactcacaacacagtccaaaagaaagtttcgtagt
cgaggttgtgcacaggccgatgatgaggacagcatggacgcctctgatgtcacaccaact
ccagacattgacatcacaccagagatggacgtgcttgagccagatacggatgatgattat
ttccctgagccactggatctcagccccagagatgagagacctctgtccccgctcttccag
cgctccgtgtcagaagactctgctggctcatctgcctccaccactagaaaagccaaaact
agagaaaagctctgtgccttctgctactgtggagaaaagagtctcttgggtcagggtgag
ctgaaactgtttggacccacgcctggttatgtccccttgcacatccggaaccgacgcggc
agctctgagaaggatgacgattaccatgatgacgacaatgatttcgatgacaaccgcagc
ccagggcatcgtgggagaggcctaaaaaaggtcagctctccagacagtggcctacactca
acctctgctcctgggagtacagaccctgctgctgaggagcccagccgcaaattctgggat
gaactgggccaaataggccttcccgatgacattaacgtttcttctttgttcgaccccact
ggccagtgttgcgctcacctgcgctgtgctgcctggtcagaaggtgtatgccgtggggag
ggacagtcgctgctgtatgtggacaaagcaattgactcagggagcacagagtgctgtgca
tactgtaagcgccttggagcatccataaagtgctgtgaggagagctgtgggcgctccttt
cattatccctgtgcagctgctgccggaaccttccagaacataaagacgtacaccctcctc
tgcccggatcacatccagcaagccctgatccgatcaaaagatgaggtgaactgtctggtg
tgtgacagttctggagacttactcgatcagcttttttgctgcacatgtggccagcattac
catggggcctgtctggacatcactgtgaccccgctgaagagggccggctggcaatgtcct
gagtgcaaagtctgcctggcgtgcaagaacccaggggaagacagcaaaatgctggtgtgt
gacatgtgtgataaagggtatcacacattctgtctgcagcccatcgtggacacaataccc
accaatggctggaggtgcaagaactgccgagcgtgtgctcagtgtggcacgaggcctaac
ggtcagtggtcgtctaatggtgtaatgtgtgaaggatgtcaacagcagcatgattcaaca
cagctctgcttcatctgtgggcagaatcaggactctggcagtcctgcagacaaacactca
tgctgtgcatgcaagagatgggttcacgtggactgtgggaggcaggagggtgctgaccct
aacaatgaggtgcaggatgggtacacctgcagagtgtgtaagcaggttcaagaggagagc
gggcacaatcagcccatcagcagccaggagccttcactctctgacccagagccaatcgag
gatgtcttcatggctgttgaagttaatgaggctaagggggaagtggcgttggagacggag
ctcaggactagtcctcttcctactcagccagaagagtttctgtcatctgctgaacctccc
caggagatccaggttacagtcactttgacagagggtcccgaacctcctccatgctcctct
actttagtgggtgtaccctccctctcctttcaggcctctaccaattctgaagaccaaaac
caggaacagactctcattggtgctttggaaatggggaaggaaacggaggataaactatct
gaagctacagaggatgaacctgaagcagatgtttcaaaagctcttcctgctttgccaacc
aaagaaacatcacccaaactctcccgagcccaagaggaagatcctatgatagtctgtccc
tcagacacctccaatatgaaggataaaatgatgacaaatgtcccagaagcccagagtgtt
gtggaggaaatcgagcagggacagaaacaggaccgaccagaacttgaagagaaggaggtg
ttagatcccgaggtcagttgtattttacctgagcctggtagtgtcccactggttgcagag
tgcagtcctacagtggaaatggacactacacctgtcagcgagcacagtttctccagtttt
agctctcccattgaggataagagcctcgttttaaagcattccccggcaatgtcgtccgag
ggctcgaccaagttgacccagtccccgttttccactgaagcctcgcccagggaaatatct
caaagccagacgccaacccacagcctgaatccagctccttacagccccagtgttttcaac
accaccttcttccctcttacacccaagattggtatgggaaagccagccatctccaagagg
aagttctctcctggaaggccaagggtaaagcagggtgcatggagtaaccgtagcgcaatg
agctcgccttcctggtctccagagcgcttggaagcctgggacagcccaaagaccaggccg
atgcacgggctgcccacctggaccatgagattgggtcgtggatctggctttcctggaagg
cggcgacccaggggaactaacctgtctggcagaggtggcaggggacgctccaggctaaag
atggagagcagccctgtggtgacccctggggtgagctttatggattctccatatgttgta
aaagaagaggaggagaactccatgcacaacactgtggtcatgttctccacctctgactcc
ttcacacttaaacaagacatgtgtgtggtgtgtgggagcttcggtcagggtgccgagggc
agactgttggcctgctcccaatgcggccagtgctaccaccccttctgcgtcaatattaag
atcacaaaagtggtgttgagtaaaggctggcgttgtctggagtgcacagtgtgtgaggca
tgtgggcaggccagtgaccccgggcgcttactgctctgtgatgactgtgacattagctac
cacacatactgtctggacccaccactgcagaatgtacccaaaggcagctggaagtgcaag
tggtgcgtgttgtgtactcagtgtggagccacgtcccccggcctgcggtgtgactggcag
aacaactacacgcaatgcggcccatgtgcgagtctcactgtgtgtcccgtgtgcgcgcgc
aactacagagaggaagagctcatcctacagtgccggcagtgtgacaggtgggttcatgcc
tcatgtcaagggctgaactctgatgaagaggtggagaatgcagcggatgagggctttgac
tgctctctatgtagaatgcacaccatgccaacttctggtggcacagtggcaaagctcatg
gacatcagcgagcctcctttagtgactcagattcttgcaaaagtcaaggaaaatgaattc
caacggacgtatactaaagatggcgtgtgtctgactgagtcgggcttgtgccagctccag
agtttatgtgtcccagctgcccgccgcagacgacccaaacctaaactaaagctgaagatc
atcaatcagaacagtgttgccgtgctgcagacgccccctgaccctcagtctgaactcttc
agggacggagatatggatgacagtagagagggcgatccgatggactgtgatgggaaatct
gactccagccccgagcgtgagccctgtgatgaccacctgaaaggggtcgacggcaacaag
aagaggaaaaggaagccgtaccgaccgggtatcggtggctttatggtgcgtcagaggagc
aaagcaggccagggaaaaggcaagcggtctctcagtcagaaagactctgcaagctcgctt
acagagaacctcacagaaaaggaacaaggttggaatgaaccagatactcccattgttagc
gagcctctggagaaagtcaagaagagatacaggaagaagaaaactaaactggaagaggtc
ttcccctcatacctacaggaagcattttttgggaaagaacttctggttaaaagcaagaag
accaagtcgactctggaaacggggcttgtggaggaagaagccaatcatacagacagcaaa
tcacaaaccagaagcttcctggaccctctatctgacccacttctcagtaccacttccact
ccagtctcatctaaagcagggcaactgcccaatgtggaggatcccttagctgagctggtt
ctacattcagatgatgatctcctgggaatgctgtccgatgacctggtcaagccaggccct
gaatcaggtcttgatttatgccctttccaggtggaccgttccccctctccattcgctggt
ttgaacattggcgccctaccggatgatcagtcaacttcccctcatcctggctcttctcga
gggtctaggacaatacaggaggaacctctggatgtaatactaagtcctgagctggacaag
atggtttctgatggggccattctgagtaagttctacaaaattccagaactggagggtaag
gacgtggaagacttattcacagcagtgctcagtccaagcgccaaccagccacctcaactt
actcattcatccaacactgcacccaatgcctcagccacagcaatgtctgtccagaaccca
ggaaatgctggtggaatgtttccacgcttgcctatgatgaacggcatgatggggccaaac
acacacattattccgaaccccatgattgctgaagctggagtgtctggcacattctcttcc
atccaccgcatgcctttttcagaaaatatgacggagaagaaattcagccagatagggggt
gatgtgatcggtccctgggcttctcctgctcccgtgcttggatctgtccctccaccagag
gtggagactgacaccatgtccaatgctcagaggagcacgttaaagtgggagaaagaggaa
acgcttggtgaaatggccacagtggctcctgttctatacaccaatatgaacttccctaac
cttccagatgaatttccagattgggcgactagagtaaagcaaattgcaaagttgtggagg
aaagctagttctcaggaaagggcaccttatgtgcaaaaggcgagagacaaccgagcagcc
cttcgtataaacaaagttcagatgtctaatgacacaatgaaaagacagcaacagcagcag
cagcagcagccagttgatccctttgatcccagcattcccatagacacagagctgctcttc
aaggatccgctcaagcacaaagaatctgagcatgaacaagagtggaagttcagacagcaa
atgagacaaaagagcaaacaacaggcaaaaattgaagccacacaaaagttagaacaggtt
aaaaatgagcagcagcaacttcagaaacaacagcaacaacagcaattcagtggagacacc
tcagagtctggtagtcagagtccagtgacaactcaaaccagcagtggtaacacttctcct
ttgcaagaattgacctccaaagatggcttccagatgcttgaaactgtaacatcaggtaca
tcaacggatgatgtatttttgcgtccccaacctccacccccttcatccacagcaaagacc
cctacccaggacactcagtacatgcagggaccctcatctcagcctcagtctcctcaaatg
ttttcaccagaatcatctggatcccgtccttcttctccgtgggatccatatggtaaaatg
gtgggaacccccaggccaccaccatctggcttaagcgcgccgcgaagaggttctttgtct
gacgttcaagataggaataggccctcaccagctcatgaatccacagacccttatgcgaag
cctccagacacacctcgaccatcagacccatttgtgaaacctatgtgtccacccagacca
ggaccattaactgagcagcaaggacgaaactgcattagtaatgtcatgcctggagacaat
ttttccaggccaggccaaagatcagaagtgtaccaacgcatggcccatagccgcatggtt
ctctctgacccctactctaggccactgttaacacctattccagggagtaatgagtctgga
tctgtgcctgtgttcaaaacacctatgcctccttcacagtttcagcaagactcattcagt
gcagggcagcaaggcatgagaagggggtcatctgatgcattctctcaaattcaacactct
gacccttattcacataagcctctaacaccccatccatcaatgggagatggtttcagtaat
gagggcagaatgatgcatccaggaccaggaggtccttttgcccaaccattgccaatgggc
agacaccctcaacgagatccatattcacaggcaccatctacacctaggccagactaccct
caacaaatgcctgatccatacgctcagcctcctggtaccccaagacctcatgatccatat
gcccagatgcctggtaccccaagaccgcactctgatccatacccattgctgccatccaca
cctagaactgtaacaattgatccgttttctcagtcacaacctaatagtcgcagacaatct
ccgtctcatgctattgatccatatgctcagatgccaggtactccaaggccttttccagga
gagagataccctaaatcaccaggtagtcagagatcctcggatcccttcttacagcctcct
ggaactcctaggccagtcaaaaatgaaacttgtgatcaatcaccaggaacaccaaggcca
gttcttcctgacccttattgtcaaccccctggtaccccacgtccaggagctgggccagaa
gccttctccagaccaaatcctagattaaactttgtggcccatcaaacagatccacttggc
catcaagcacaaagtaggatacaggacccatttgctcgtccctgtgcccttgattctcaa
acccccaaacatcctgcgatttcagatgaaagtctctccctacaacagacaaatcctaac
aagacacctattcatgatccttttgaacaagcttcactaaccccatgttcacaagcaggg
gagagattgtcacatgatgtttcagtaaacacgggcaacccatcggattcacagaacaca
atgcaaccaccacttggagagactgaagagaaaattaaacagcgccaaagactacggcag
ttaattctcagacagcagcagcagaaaagtgcgatcagactagaaaaaggactccaggag
gcaactgctactgcagcacctgggactccaaggcattggtcacaggatgattctggacct
cagaaggatatttttggtagacccccacctccatatccaggtactatgagatcatcagca
attaatgcagggcaaaggtttcctggaaccttccttgccgatcaacatgggtccatgtct
gatgaaccccagtgctcccggccgccattacccagagacgtcaacaacatgagaccgcaa
ggacaaagatttggatttcctcctggagcaccaaaccaagaacaattcatcaggccccct
caccaaatacaaggtggaccaatgcttgacaatatcccaccacatatgagacgacctctt
tctgttgacattgctaggcaaataggcagtaatcatcagatgggccttccccagcatttt
ccaccacgtggcctttcaatgcaacaacataatataatgggtcaaccatttattgaactt
tgtcacagggctccagagaacagagtcaggctaccgtttgggccacctaatgctttggat
catcctaatcatcctcagagacctcctcatggcttcatgggaggccaaaatatggccttt
acaggaaatcaaggtcccagaataatggatcagatgttgggcctttcacatcaaggatca
gtcagtcacatgcagacttcaactaatatggataacctgcatcaccatacaaatacagtt
ccacaacagactacagtggcagtaccacttcgccatttggtcagtagggattcagttact
cccagcgaatctgcactactccctgtcacaacatctggaccaacagaggaaatcccattg
ccatgtagtgatggtgttgttgacaagctagaaacggatgactctgctgtgaaggatctt
gatgatgtggaggtcaaagacttggttgatgaggacctggacaacctgaaccttgatgca
gatgatggcaaagatttggatgatcttctggaatctggaaagtttgatctgattgcttat
gcagatcctgagaaccttggggacaaaaaagacatgtttaatgaagaacttgatttaagt
gatcacatagaagatgaccatggggatacctctgatcttcagaaggccttgtctgaaaaa
agaaattccagatgtgaaggtgtatcatcagctcaacctaaaccagaggccatacaaggt
cctagtaatgtcaaactagaaaaaagtctgtcaaaagagtttctggattctcagtctgaa
agaactatgaaaactgagagccagggttttggaaactcagtggatgaccatcagcccatg
agtagtaaaagtggtcaagacgatgtctctgttctttttgaggagtctagtgcacatggc
catcctggatctgctccagtgttgtcaagcctgttgatcaaggaaaagctaggtgaaact
aggagtgaatccataatttctcccatctcggctgaccctgatgcccagacgaatcttggc
tccaacatgagtatggtgatgctgcgaggacaacccgaagatcacgggataaaccctgga
gtagctatggggcacagagtagatccacctctaacccaagggccaatattaggtaaccca
aatttgatgcagtctgagaaccagcaggtaccaaatctagggtttggagcatcacaagga
cagcaagtggatctgaacctgcctatagttagtgctcagcagcctgttccccattcctta
aacctacaaactcagcagggcatgttcaatccaggggccacagggcaacaggggtctcaa
gtgcaacaaaatcaacacaacagacctcttctgttagatgagcagccccttcttctacaa
gatctgctggatcaagagaggcaagaacaacaacagcaaaggcagatgcaggccatgatt
cggcaacggtcaaatgacccttttttccctaacatcgactttgatgcaattactgatcca
atcatgaaggcaaagatggtagctctaaaggggatcaacaaagtgatggtacagaacagt
atggggatgacacccatagttatgaacagagtgcaacagattccaggatcacatgcccca
gatacagctggtttttcacaacattttttggatggaaagttgccaccacagattgcgaga
cccaatccccctaactttggaccagggtttgtcaatgattctcagagaaaacaatatgag
gagtggcttcaggaaactcaacagcttcttcaaatgcagcagaagtttttagaggaccag
attggggcccatagaaaatctaaaaaggctctctctgcaaagcagcgcactgcaaaaaag
gctggacgggagttcccagaggaggatgcagaacagctgaaacatgtgactgaacagcaa
agtgtggttcaaaagcaactagaacagatacggaagcaacagaaagaacatgctgagctc
atcgaggaataccgtgtcaagcagcaacaacagcaacagcgcctccaacctgctgtgatg
ggtccaataaaggccatgccaggaatgcaaggacaaccccctccagtgatgcctggtgga
ccccctatgggccagcctatgttgggtcctatgctgcccatgcaacaaccccactttggg
aagcctactcgcatgtccaacgtgccacgttggcatcctggtactactggaccaatgcct
ggacccaggatgccgcctcacctgccccctcagatgccactacctaacccctcccagcct
ctccagacacagccaccttcccccatggttccaggaggtaaacctgggcagcctggcact
gtagctggaggtaatggtggaggagccagtaatagtagtagtgcccctcacgtgaagttt
gatgataataatccattcagcgaaggcttccaggagcgggagcgtcgagagcgccttcga
gagcagcaggagaaacagcgggtgcagttaatgcaggaagtggagagacaaagggcattg
cagagactagagctggagcagcagggcttggggcttggccccaacaacagcggggatggt
cttacccagatgcccttctataattcagacctgtcacaggaattcatgcagacacccagg
aataaacaacaaccacagcaaattggcccagtgttccctcagcaaggaaacacgccgtta
gactttgtaaatccaggctttttgcaaggtggcgagcgcaggccaatgcccgggaatggt
tcctttggcccagatataagttctaattttcagcctaagaaccccatgatgcatggtttc
accccaggtcagccacgtctacctgggtttggagggcttggaatgcctccccacggtgga
ggtgaaacttcctcatttggcgtggaatccacaacttctttacctcctaatttccctggg
gcaggacagtcccttatccagctctattccaacattatccctgaggagaagggcaaaaag
aaaaggagtcgaaaaaagaaacgggatgatgatgcagattcagtcaaaactccttccaca
cctcactctgacatcactgccccacttacaccatgtgtatcagacacctcatccacacca
acacgcagtgttgccatcatgggagaccaagacgctttagaccaagacccactttctgga
ggtactccactagggcgacagtccagcgtgggttcggaggcagagcgaggccttctctgt
gatatcaagctggaaaagttagaagctagtgtgtgtcagaggggtgaaggagaagcaatg
tttggccatagtgcaggaggaaccggaatagtaaagacagaagagggcaatgagatcatc
tcccccagcccagcatccaagagtccagttcagagcactaaaggggacactgggaatgag
ttgctcaaacaccttctgaagaacaagagcacccctcctccttcctcaactcctctcata
catcagatgtccaatgacagtattcaatcagaggaagagggcctgaatgacagcaaaggc
tctttaagactggacagcacagattctttgagtggcatcaacagccagacggggaatcca
gatctagagcctttagtgccagaccaaagcaagagaaaacaacgcaacaagcggacacca
aagaatggggctgagaaaccaccatcacgctggaaaaagaggaagaaggatgacgaagag
agacaagcagtgtacacaaacacagacacgctaatgactcagctcaagcagcagctttct
atgttgcccctgatggagcctttgatcagggtaaactttgcacatttccccctgtatggc
agtgggcagttgaacggtgagaacaggctctctggatcatttggaaatgcatcattggat
ggagtatctgattactactcgcaacttatctataagcagaacaatcttagcaatcctcca
acacctcctgcctcactgccccccacaccgccacctgttgccaggcagaagctgttgaac
ggctttgccactgcagaggaactggccaagaaggcagaaattatggtttctaaaagtttg
ggtcagaagcagctcaaagctccattcaaagctgaagatgacctgctaggacacaccatc
actcagggcccaaagactgttgatgttcctgcttcgcttcccactccaccccacaacaac
caggaagaactgcggggtcaggagcattgtgtggacagggacactccagacagttttgtc
ccatcatcttctcctgagagtgtggttggcatggagatcagccgttatccagatctgtct
agagttaaagaggagccaccatcccctgctgtctctccagtcattcctatactggatggt
aacggttctgaagccaggcagtgggaagtcaaggcagagccaccaagcaatttctttgct
tcgcaatttggacagcacttaagaactgacctggtgtctgtatctgttactctgaaccca
gtggcaacacataatataccaggagtggtgtcagcactggcgaacatgctttgtgtgtcc
ataccgaggaactatgaggtgattcgctctccaggccaagaacaccgcagctcaatggac
atgtttagtgaacttagggtcccccctcaaactgctctgtaccaccaacagcctggtatg
aggctcctcagaccaccgggtgccccactaccacaccaaacattcatcgagggttcagtt
gtggtcagaccagactatcccatgggtggaagcagtccagggcctaaaccacagtggtgc
tcccattgcagggttgtgattcttggcaatggggttcggaagtccactaaagaccttccg
ataaataaacagggccatggaggatctgaggggagccttgtcttctgcagccataactgc
tttgttctctattcagcctccatgcagaataaattgttagatggcaaaccaaacgtgctt
ccaccatctgactctgaggataagcataatcccactaaggtatttcatcaatacagtcac
aatatgtccgatcttgacgtgcactgtttggctcagctgcaacccaagcagtctccaccc
ccaactcagataatatccttcccctccatcacgtctgagactctccgaggagatagcaag
tctgatactctaaaggtcacagtgaagcttaagcctcggccacgagcggtacacaacggt
gtggatgaccctcgatgttcatttgggaagcgctggaaagctttacgttggagaaagtgg
agtgttcaaattgtggtgcctaagggtaactaccacttgccaggggaggaagaggttgat
gaactactgaagaaactggggacgtctcttaggcccgagcccatgcccaaagacttgcgc
cgctgctgcttctgccacgaagaaggtgacgggctcaccgacgggccggcccgtctacta
aaccttgatctggatttatgggtgcacctcaactgtgccctgtggtctactgaagtctat
gagacccaggctggagctctcattaacgtagaactggccctgaggagaggcctatcggtg
cgctgtacatactgtcagcaaatcggtgcaacgagtggctgccaccgcttgcgctgcact
aatgcataccactttacttgtgcccttaaagcacagtgcacattcttcaaagataagact
atgctgtgccacctgcacagacccagaggaaccggctcaatgggaggtgggctggcggga
accgagcatgaacttcgctgctttgccgtgttccgtagggtctacgtgcagagggacgag
gcacggcagatcgccagcatcatccagaggggtgagcgagaacacaccttccgtgtgggc
agcttggtctttcactcagttggtcagctgcttcctcaccagatgcagaatttccactcg
atgtctgccattttccctgtgggctacaaggccagccggatctactggagcatgcgccat
gggaaccgccgttgccactacgtttgttccatcgatgagaaagactgtgaccctgagttt
atcatccgtgtggtggagcagggttatgacgacttggttcttactggatcctcaccgaaa
ggcgtgtgggataaggttctggagcctgtggcggagagaaggaacgaggcaggatctctg
aagctcttccctgtttacctgaagggagaggacctatttggactgactgtgtctgctgtt
accagggttgtggaatctcttcctggagtggaggcatgtgagcagtacacgttccgttat
ggccgtaaccctctgatgcagttgcctttggccatcaacccctctggatgtgcccgctct
gaacctaaagcttgcacacatgtcaagaggtttgtgttaaggcctcacaccctgaccagc
agcagtttctctaaggccctggcgagctctgggaacccggctgagatgggtgtcgcacca
tacagcaagcattttgtccattccaagtcctttcagtaccgtcggatgaaggctgagtgg
aagtccaacgtctacttagctcgttcacgtatacagggtttagggctgtatgctgctagg
gacattgaaaaatacaccatggttatggaatacattggtaccatcattcgcaacgaggtg
gcaaacaggaaagagaagatgtacgaggcacagaatcgtggagtctacatgtttcgcatt
gatagtgagcatgtcattgatgcgactattacaggaggacctgcaagatatatcaaccac
tcctgtgcgcccaactgcattgctgaggctgtaacctttgagagagatcacaaaatcatc
atcacttccaaccgcagaatccagagaggcgaagagttgtgttacgactacaagtttgat
ctggaagacgatcagcataaaatcccttgtcactgtggcgcagttaactgcaggaaatgg
atgaattga

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