Pimephales promelas (fathead minnow): 120478925
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Entry
120478925 CDS
T08155
Symbol
brca2
Name
(RefSeq) breast cancer type 2 susceptibility protein
KO
K08775
breast cancer 2 susceptibility protein
Organism
pprm
Pimephales promelas (fathead minnow)
Pathway
pprm03440
Homologous recombination
pprm03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
pprm00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
120478925 (brca2)
03460 Fanconi anemia pathway
120478925 (brca2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
pprm04121
]
120478925 (brca2)
03036 Chromosome and associated proteins [BR:
pprm03036
]
120478925 (brca2)
03400 DNA repair and recombination proteins [BR:
pprm03400
]
120478925 (brca2)
Ubiquitin system [BR:
pprm04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
120478925 (brca2)
Chromosome and associated proteins [BR:
pprm03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
120478925 (brca2)
DNA repair and recombination proteins [BR:
pprm03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
120478925 (brca2)
FA (Fanconi anemia) pathway
Downstream FA components
120478925 (brca2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
Tower
BRCA2_TR2
Motif
Other DBs
NCBI-GeneID:
120478925
NCBI-ProteinID:
XP_039527056
LinkDB
All DBs
Position
Unknown
AA seq
2838 aa
AA seq
DB search
MFENFYHQIDKELGPLNPDWFEELTAKASRDEGRPDSFKAEWEEETVKEPETSALASQLN
STPKIFKQQQFQSPDSIPNEESPYEDISAFPWSESSPCLFGSAKARSDRSCEKPRDCFGL
LETPKRSLARSAKLISESLGAQINPDLSWTSSFNTPSSLTPTVILPKTEDRAPSSSGLKD
KEAIFVRKLFPSLSKSSASTASLNDTTLKRDAKSETIQVDDLGENPVCSPNASLDTSGLW
KQTVPSAIEDGDVRTTVQNVLDGAEDALSIFFSNSTSTLRRIKTKERIRRRISDSSKDVK
SVVLTTGPEDILKADVETKSPNKNKDIIQWTPLSLSECILLNGDGDCSGASLMNNHNTVA
SCETDGFTVFNCTGESSQTFSQSVRLKSYPAETERHKTSSAFMKSPAFMLTRKSRKFVYQ
VPNSDLSKTVIEHKAALPVCSDHTDKENSSFEKESCDLNKYRFASEYAINNQTTLQAVEP
LSTEPHDLDPGLDMTQLSKAFAEDFTQEIRPGLLLDVPVKSDQNYQEQPKAEFEENKVGN
HNDISNLAEMSVNSPNKSTVMLTTFDISHDSGCPTTFSDLDGTTASCADLKEFCPTFQTA
NNKAIFVPSEAVMKAKASLDEAAGDGLSITLNQTTPKHYQTIETLCKSVSGSTNATRSSV
GQFIFPNHASITCVSDVPKSDSPNRFKMNISSYSSPQSNESDYKTGSKRNSTALDVSLQT
ETLLKAKLWRDSSKCINQKLDFKRSAERQAVSNITSTHKPTAVDSSCDDEKNGTLTASQK
ADVTELCNLLEEANSQHEFTQLKPTNLGSENNTTTEREWDPDIVNGIDFDDSFNCDFVKG
KHPVKKDASLVNSSDHSQIVDAAKLCTMSKETRNGTVPLSVTEDSSLVDGLKNVLSNFTD
NTQFHCLGFKTAEGKLISISEKSLNNAKNFFEEDGQEVDFGVKKLEYSDTSDSISTENKT
HVKKLGTCKQDSLELQTCVLALHASGKHDASMSKKGLQKTKAVSWSEPSIKMNQRDSVVG
NQISDVPDIPSFSSENVFQEQKSSNDAKEVCANIFPSDTFVPQSGQGYGFQTASGKAVSV
SASTLKKAKGIFKDCDSNINSLESAIMEGKNDKPVEILEQTNAFISNCKNVSFSNVEKAK
TVLGDTDLINDFSLQSSLDQQTPQEKVCEKKDIQNEFPKHLSELLPLNGTCGFSTASGKK
VSISAGALQRAKDVFFESVDDIECANSSPKTKQVVDIKTDYVSSREHKGFCTAGGMKVTV
SATGLQRAKDIFRDCEEESLSSQDRLHQNCKGFSNVSEKTLIKVKPKFAGSSDVPFSHEP
ETGNSPGKTVGFSTAGGKKVDISATALQRAKSLFNDCEEEVASVSLQHQACKDFSTASGK
DVTVSEKALMDVRAAFAGCEDASFSRDLKISSGNNVGFSTAGGKKVAISATALQKAKSLF
NDCEEENLASGSLQHQDCKGFSTASGKDVAVSEKALREVRAAFAGCEDASFSHDPKNSSG
NNVGFSTAGGKKVAISATALQKAKSLFNDCEEENLASGSLQHQDCKGFSTASGKDVTVSE
KALRDVRAAFSGCEDASFSHEPKHSSGNNIGFSTAGGKKVAISATALHRAKSLFKVCEEE
NLTSMELSLEKVLPQTKSSHRKSEDTVDENLKFEQLKKKNCRFSTASGKGVSVSKVALEE
ASKLFRDCDAQVTSTDNQLLQSDFSKHCTPHKERQSETTLLPLPSKVTQNIPAQLDLNSL
DFKSCTETQQEYFEQEAMACTEALLADDDLNESAKLVMSEGTDYQERLSINDRQTQGSFD
QNRRRKRQFDSCSIADTGQPPLKRQLLSEFDRTLDAKSSGLKPLKSCPTGTLKDRRVFKY
NVLLKPNVTAPNWHHVGEKSNYLENHCSTVSVQNRRNSDTKGWVFVSPFQEVMMTGTSNC
QHVSKVSSGFMPPFKKENKEKTDHSNQMDQKVKASTSHSDSNLHEGFKPKSTTSLESGVK
IMKSKEKDTEVGQETLDLARDMQDMRLRKKKRQTIRPLPGSLYLAKTSGVPRIGLRFAVG
CKCPGQYTKEELYQHGVHQKVSKITSENAESFRFDCNDFFKREQLIESGAVQLADGGWLV
PDSKGTVGKEEFYSALCDTPGVDPKLISDAWVFNHYRWIVWKRASMERSFPVLMGSRCLT
PEQVLLQLKFRYDVEVDHSHRSALRRIMERDDTPAKTLVLCVCGVAKTCQNPEKPVKDEK
TPNAKMESCVIWLTDGWYAIKGILDPPLSAMLNKNRLRIGDKIVTSGAELVGSQEACTPL
EAPESLMLKISANSTRRARWDTKLGYYRDPRPIRLQLSSLYPAGGVVSCVNIVVLRSYPT
QWMEKKPNGVFIFRNDRAEEREARKHSNSKHKSMDLVISKIQTQFEKEMEGNKKCRKQRR
TFSRHEIEALQDGEELHEAMEQDPAVETHVSERQMEAVSKYRRCLEERSQAELQERVQKA
ILEAQEAEGGCPNRDVTPVWKLSITDANDLQNDRVYTLNIWRPSRDLHGLLREGHRYRAY
HLATSEGKKRSGIAHIQLTATKKTLFQDIEVSPEWLHQHFLARECVRFRELQNSQFSSPC
GEVDIVGYIVSIVGKQGNCPVLHLVDENFDLVSVRTYSSLEQLAVEELVKPRALIALSNL
QVRPLSGPVPSLCAGEQALFSVNPKESHLQEAMAHLKTFAQTCEEFFSIAEEKVSDVVPS
GALDCFQSPRTPSVQFYPKMNGRVTPQQKSSGFSPFTPLNRRTPVSASNSEGKDPIYLKR
RQGLDYLSRIPSPPPITPLKTRASPCVSNTFNPPRRSVTPKPPQNESPRASRPPPGEEWV
HDDELAMIDTQACRYWMG
NT seq
8517 nt
NT seq
+upstream
nt +downstream
nt
atgtttgaaaatttctatcatcaaattgacaaagagcttggaccccttaatccagactgg
tttgaggagttgactgcaaaagcttcccgagatgaaggtcgtcctgacagttttaaagca
gagtgggaagaggaaactgtcaaagaaccagagacatcagccctggccagtcagttgaat
tcaacacccaaaatatttaagcaacaacagtttcagtcccctgattccattcctaatgaa
gagtcaccttatgaagacatatcagcttttccctggtcagaatcgagcccttgtttgttt
ggctcagccaaagccagatctgatagatcatgtgaaaaacctagagattgctttggcctt
ctggagacaccaaaaaggtctttggcacgttcagcaaaactgatatctgagagccttggg
gcacaaatcaaccctgatttatcttggaccagctcatttaacacaccatcctctttgact
cctactgtgatattgccaaaaacagaggatcgtgctccctcatcaagtggcctcaaagac
aaggaagcaatttttgtgcggaaactgttcccatctctttcaaaaagctctgcaagcact
gcgtcattaaatgatacaacattgaaacgagatgccaaaagtgagactattcaggttgat
gacttgggagaaaatcctgtttgctctccaaatgcctctctggatacaagcggtctgtgg
aagcagacggttcccagcgctatagaggatggggatgtccggaccacagtgcagaatgtt
cttgatggtgctgaggacgcattatcaatattcttcagcaacagtacttcaactctgcgg
agaatcaaaaccaaagagaggatcagaaggagaatatccgattcttcaaaggatgtcaaa
tcggttgttttaactacagggccagaagacatattaaaggctgatgtagaaacaaaaagc
ccaaacaaaaataaagacatcattcagtggaccccactaagtttatccgaatgtatttta
ttgaatggagacggagactgttcaggggcgtctttgatgaacaatcacaacactgtagca
tcctgtgaaacggatggttttactgttttcaactgcactggagaaagtagccaaactttt
tcacagagtgtaagactcaaatcttatccagcagaaacggagcgtcataagacttcatct
gctttcatgaaatcacctgctttcatgctcactagaaagtccaggaagtttgtatatcaa
gtgccaaattccgatttgtcaaagactgtaattgagcacaaagcagctcttccagtatgt
tcggaccatactgacaaagaaaattcctcatttgaaaaggagtcttgtgaccttaacaaa
tacagattcgccagtgaatatgcaatcaataatcagacaacgctgcaagccgtcgaaccg
ttatctacagaaccccatgatttggaccccggattggatatgacacagctttccaaagca
tttgcagaggatttcacacaagaaataaggcctggattgctgcttgacgtgcctgtgaag
agtgaccaaaattaccaagagcaacctaaagctgagtttgaagagaacaaagttgggaat
cacaatgacatctctaatttagcagaaatgtctgtcaactccccaaacaagtcaacggtc
atgctcacaacttttgatatcagtcatgatagtggttgccccactaccttttcagatttg
gatggtacgacagcctcatgcgcagacctcaaggagttttgtcctacatttcaaactgca
aacaacaaggctattttcgtaccaagtgaggctgtaatgaaggccaaagcatcattggat
gaagctgcaggggacggtttgagcatcactttaaatcaaacaactccaaaacattatcaa
acaattgaaacattgtgcaaatcagtttcaggaagcactaatgcaaccagatcttctgta
ggacagttcatcttccccaaccatgcatcaataacgtgtgttagtgatgtgccaaaaagt
gacagtccaaataggtttaaaatgaatatttcaagttactcttcgccacagtcaaatgaa
tctgattataaaacgggttcaaagaggaatagtacagctttagatgttagccttcaaaca
gagactcttttgaaagcgaaattgtggagagattcatcaaagtgcattaatcagaaactg
gattttaaaagaagtgctgaaagacaggctgtgtccaacattaccagcacacacaaaccc
actgcagtggactccagctgtgatgatgagaagaatggtactttgacagcttctcaaaag
gctgatgttacagaattgtgcaatcttttggaggaagcaaatagtcaacatgaatttacc
cagctcaaaccgacaaatcttggctctgagaacaacaccactacagagagagagtgggat
cctgacatagtcaacggcatcgactttgatgatagttttaactgtgattttgtgaaagga
aagcatccagtcaagaaagacgcttctttggtaaacagttctgatcatagtcaaattgta
gatgctgccaaattatgcaccatgtcaaaggaaacacggaatggtactgtgcctttgtca
gtgacggaagacagttctttagttgatggactgaagaatgtgctgtctaattttactgat
aatactcagttccactgccttggatttaaaactgctgaagggaaacttataagcatctct
gaaaagagtttaaacaacgcaaagaacttttttgaagaggatggtcaagaagtggatttt
ggcgtaaaaaaattggagtattctgatacttctgacagtataagcacagaaaataaaacc
catgtaaaaaaacttggaacttgcaagcaagacagcttggagttgcaaacttgcgtactc
gctctccacgcttctggaaaacacgatgcctctatgtctaagaaaggccttcagaaaaca
aaagctgtttcttggagtgaaccctctataaaaatgaatcagcgagactcagtggtggga
aatcaaatatctgatgttccggatattccttcctttagcagtgagaatgtcttccaagaa
caaaaatctagcaatgatgctaaagaagtttgtgcaaatatatttccctcagatacgttt
gtgcctcagtcagggcaaggctatggttttcagaccgccagtgggaaagcagtttctgtt
tcagccagcacccttaagaaggcaaagggcatattcaaagactgtgattcaaatattaac
agcttggaatctgcaattatggagggaaagaatgacaaaccagttgaaatacttgaacaa
acaaatgcgttcatttcaaattgtaaaaatgtttcattttcaaatgtggaaaaggccaaa
actgttctcggggacactgatctaattaatgacttctcattgcagtcctctttggaccag
caaacccctcaggaaaaagtatgtgagaaaaaagacattcaaaatgaattccccaagcat
ctctctgagttgcttcctcttaacggcacctgtggtttcagcacagccagtggtaagaag
gtatccatctcagctggagcactacagagagctaaagatgtattttttgagtcagttgat
gatatcgaatgtgctaatagttctccaaagacaaagcaggttgtcgatatcaaaacggac
tatgtttcctcaagagaacacaaaggattctgtacagcaggtgggatgaaagtgactgtc
tctgctactgggctacaaagggcaaaggatatcttcagagattgtgaagaggagagttta
tcatcccaagatcgtctgcaccaaaactgtaaaggtttcagcaatgtctcagaaaagact
ctgattaaggtaaaaccaaaatttgcaggttccagtgacgtccctttcagccatgagcct
gaaactgggaattctccaggaaaaacggtaggattctctacagcaggtggaaagaaggtg
gacatttctgccactgctcttcagagggccaaaagtctgtttaatgattgtgaagaggag
gtagcttctgtgagtcttcagcaccaagcctgtaaagatttcagcactgccagtggcaaa
gatgttactgtctctgaaaaagcactgatggacgtcagagcggcatttgcaggttgtgag
gatgcctcgttcagtcgtgaccttaagatttcttcaggaaacaatgttggattctctaca
gcaggtgggaagaaggttgccatctctgctactgcacttcagaaggccaagagtcttttt
aatgattgtgaagaggagaatttagcctctgggagtctacagcaccaagactgtaaaggt
ttcagcactgccagtggcaaagatgttgctgtctccgaaaaagcactgagggaggttaga
gcagcatttgcaggttgtgaggatgcctcgttcagtcatgaccctaaaaattcttcagga
aacaatgttggattctctacagcaggtgggaagaaggttgccatctctgctactgcactt
cagaaggccaagagtctttttaatgattgtgaagaggagaatttagcctctgggagtctt
cagcaccaagactgtaaaggtttcagcactgccagcggcaaagatgttactgtctctgaa
aaagcactaagggatgttagagcggcattttcaggttgtgaggatgcctcgtttagtcat
gagcctaaacattcttcaggaaacaatataggattctccacagcaggtgggaagaaggtg
gccatctctgctactgcactccacagggccaaaagtctctttaaagtttgtgaagaggaa
aatctcacatctatggaactttcattagaaaaagtactgcctcagactaagagttctcac
agaaaaagtgaggacactgtggatgaaaacctaaagtttgaacaactaaaaaagaaaaac
tgtcgtttcagcactgctagtggtaaaggtgtgtctgtatcaaaagttgcccttgaggaa
gcttctaaattattcagagactgtgatgcccaagtaacatctactgataaccaactgcta
cagagtgatttctcaaaacattgtactccacataaagagagacaatccgaaaccactcta
cttcctttgccatctaaagttacgcagaatatacctgcacaactagacttgaactctttg
gattttaaaagttgcacagaaacccagcaggagtactttgagcaggaagcgatggcttgc
actgaagctttactggcagatgatgacctgaatgaatcggccaagttggtgatgtcagag
ggcactgattaccaagaacgtctatctattaatgatcgacagacacaggggtcatttgat
cagaacaggaggagaaaacgtcagtttgattcatgcagtatagcagacacagggcagcct
cctttgaaaagacaacttctctctgaatttgaccggactttagatgcaaaatcctctggc
ctcaaaccactaaaaagttgtccgactggaactctaaaagacagacgcgtcttcaaatat
aatgtccttcttaagccgaatgtcactgctcccaattggcatcatgttggcgaaaagtca
aattacctcgaaaaccattgttctactgtgtctgttcaaaacagacgcaactcagacacc
aaaggatgggtgtttgtgtccccttttcaggaggttatgatgactggtacatcaaactgt
caacatgtttctaaagtctccagtggttttatgccacctttcaagaaggaaaacaaagaa
aaaactgatcatagcaatcagatggaccaaaaggtgaaggcttctacttcacatagtgac
agtaacctacatgagggttttaagcctaaatcaaccacatcattggaaagcggagtgaaa
atcatgaaatctaaagagaaagacactgaggtagggcaggagaccttggacctcgccagg
gatatgcaagacatgaggctaagaaagaagaaaaggcagactattcgtcctctacctggc
agcctttaccttgctaagacttctggtgtccccagaattggtctgagatttgcagttgga
tgcaaatgtcctggtcaatacacaaaggaagagctttatcagcatggtgttcatcagaaa
gtctcaaaaataaccagtgaaaatgctgaatcattccgatttgactgtaatgacttcttc
aaacgtgagcagctcattgagtctggtgctgtccagctggcagatggaggctggttggtt
ccagacagtaagggtactgtgggcaaagaagaattttatagtgcattgtgtgacacccct
ggtgttgaccccaaactgatcagtgatgcctgggtgtttaaccactaccgatggattgta
tggaaaagggcctccatggaaagatcctttccagttttgatgggtagccggtgtttgact
ccagagcaagtacttctgcagctgaaattcagatatgatgtggaggtggatcacagtcat
agatctgctcttaggaggatcatggagagggacgacactccagcaaagacattagtgctt
tgtgtatgtggtgttgctaaaacttgtcaaaatccagagaagccagtgaaagatgaaaaa
actcccaatgcaaagatggagtcctgtgtgatctggctcacagacggctggtacgccatc
aaaggcatcttggaccctccgctctctgccatgctgaacaagaaccgtctccgaatcggt
gataagattgttactagtggagcagagttggttggctcccaagaagcctgtactccacta
gaagctcctgaatctctgatgctaaagatttcagccaacagcacaagacgagctcgatgg
gacactaagttggggtattatcgtgaccctcggcctatcaggctccagctatcctcattg
taccctgctggcggtgttgtgagctgtgtgaacattgtggtgttgagaagttaccccact
cagtggatggagaagaagcccaacggtgtctttatatttcgcaacgatcgtgctgaagag
cgagaagccagaaaacacagcaactcaaagcacaaatccatggatctcgttatttctaaa
atacagacccagtttgaaaaagaaatggaaggtaataagaaatgtcgaaagcaaaggaga
acatttagtcgacatgagattgaagctctgcaggatggggaagagttgcatgaggcaatg
gaacaggatcctgctgttgagacccatgtaagtgagaggcagatggaggctgtgagtaag
tacagacgctgtctagaggaaagaagtcaagcggagctgcaggagcgtgtgcagaaggct
atattggaagcccaagaggctgagggtgggtgtcccaatcgagatgtcactcctgtttgg
aagctcagcattaccgacgccaatgacctgcagaacgaccgtgtttacactctgaatatc
tggcggccgtcgcgggacttgcatggcttgctaagagagggccacagatacagggcgtat
cacctcgccacatctgaggggaagaaacgctcaggcattgctcacatacaactcactgcc
accaagaaaactctctttcaagatattgaggtgtctccggaatggttgcatcagcatttc
cttgctcgagagtgcgtacgtttcagagaacttcaaaactctcaattcagctctccttgt
ggggaggtggacattgtgggatatattgtctccattgtgggcaaacaaggaaattgcccg
gtactgcatcttgtggatgagaactttgatctggtctctgtgagaacctacagtagtctg
gagcaattggctgttgaagagctggtaaagccacgagcactgattgcgcttagtaatctt
caggtgagacctctttctgggcctgtgccaagcctttgtgctggagaacaagcactattc
tccgtaaaccccaaggaatcccatctgcaagaagctatggcccatctgaagacttttgca
cagacttgtgaggagtttttcagcattgcggaggagaaagtctcagatgtggttccttca
ggtgccttggattgttttcagtctccaagaacccctagtgtgcagttttatccaaaaatg
aacggcagggtaaccccacagcagaaaagcagcggtttctcgcctttcaccccgttgaat
agaagaacacctgtgtctgcaagtaacagtgagggaaaagaccccatatacttgaaaaga
agacaaggtttggactacttatcacgtatcccgtcccctccaccaatcacccccctgaaa
actagagcttctccctgcgttagcaacacctttaatcctccaaggagatctgtgactcct
aaacctccacagaatgagtcacctcgagcctcgcgtcccccaccgggagaggagtgggtg
catgatgatgagctggcgatgattgacacccaggcttgtcgttactggatgggctaa
DBGET
integrated database retrieval system
