Pimephales promelas (fathead minnow): 120488508 Help Entry 120488508         CDS       T08155                                  Symbol pkd1a Name (RefSeq) polycystin-1   KO K04985   polycystin 1 Organism pprm  Pimephales promelas (fathead minnow) Brite KEGG Orthology (KO) [BR:pprm00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:pprm03037]     120488508 (pkd1a)    04812 Cytoskeleton proteins [BR:pprm04812]     120488508 (pkd1a)    04040 Ion channels [BR:pprm04040]     120488508 (pkd1a)    04091 Lectins [BR:pprm04091]     120488508 (pkd1a) Cilium and associated proteins [BR:pprm03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    120488508 (pkd1a) Cytoskeleton proteins [BR:pprm04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     120488508 (pkd1a) Ion channels [BR:pprm04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    120488508 (pkd1a) Lectins [BR:pprm04091]  C-Type lectins   Others    120488508 (pkd1a) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PKD REJ PKD_4 Polycystin_dom PKD_channel PLAT LRR_8 Lectin_C LRR_4 WSC Ion_trans Y_Y_Y LRR_LRWD1 LRR_5 K319L-like_PKD Motif Other DBs NCBI-GeneID:  120488508 NCBI-ProteinID:  XP_039541161 LinkDB All DBs Position Unknown AA seq 4623 aa AA seqDB search MPCRNGQIVFKRKHGVCLPKFGLFSSLLFALFCLEARSGVTADGGACSPCPGNCSCTAVG PQNLCVVNCSNIGLDQAPAASGLPTETHTLDLSRNHIPSVDWSLFDHLTALKELYLQSNR LVTLPHGIFGCGPLTVLDLSNNQITTIEERTCDNLFNLTTIDLSSNPFVCDCKLVRLVGW LQEKGVRVKRPNSMLCDRPPEVKNQPLLNVSVHTCGLTYAGCLEDEEHVAGVELVIFSSS TPGPFSREECNSKCFHENQLYGGLGQQRECLCSTNSEPNHISESQCSAACANPQVMKKCR WTVAHDVFQVNFSASLPSRRVSVHSEAVLSVTSSVFPASLSWDFGDLSPRVNSSTPNTTA RHKYGVPGRYQAQVSLSAGHQEIVAQGGVSVDLPPRLELHCPALVVANQSLEAELSLVNW GGVGVTVDWRIQKDGREIAKAEPLCLPDALHHTDSSRCFLLVLEEVSWSDARRDCSARGG ELAVVHSQTVRDLLAPRITHERGVWLGLSDQYSPRVLRWVDGSEVRSGDEGSRDRATLQP GNVCVSLDASGQPSSHSCTAKRAFVCQFTRQVRVPDAGVYTVGTAVFNTHSPLRSPTATH TSVPNTPAKSVELLLFPGLSFLNAGRLSSVDLNTHSLSADTQLRLQVYRPKCQRFTRTLL PGCGDLCAPITVCQAPDEWINDTSVRAEPTPCPAGRQYCPYAEQCLPLSSPCHPGACVNC SGVSPLPAGTQYPDYSLVGEVLVTLPAGPPSNVLVQEEIEDLLVSPGDFIALQHDAGPSG LLQCSSEPSSPWKQSVLIQNRSDWWDANETLLADAEGSWEEGVVCQMRVLYVGQNDTRLQ GPFLRSGLPQSGEYSLEVTSNDKDFPVTASCPIRAVPPLAPTVIHPINHSGTVYFLPNQT WILVAVRSQHDASIEREGGNATVAFRSSCPQHLVAKVAECRRPGPFNDTMFAWVDLQLGS TPGQTAVVLRVKSEVTEASLQIEARVQERLRGLVVHPHPAHRVLMESIVSYVASVEEGSD PSFKWTVDDNPNFTYYSSNLNIIYQIAGVYKLVVTAMNQVSMLSELFNVTVDPMNPMTVP AVHGVPRIVQQGLSLNLSASVKIDMAVNVTFWWWFGDGGNRTHQFKPPYNNSYNNQVVIR DHVEYIYAQPGEYTLMLSASNRYENKTCKVDVYVFSILTSVRIEIYPPLLRAEKPADFEA HPLPSPYGIIYTWNFGDNSSIQQGRERRVPHAYAHSGVYNICVIVNNTISWTGTCAEVTV YEDVKGLEVASSAPTERNTRTVVTASLEAGNNVTWSFDMGDGTVFTGVEPQVEYSYRKDG NYTVNVTAKNAVSSQWVTLPVEVFVLQVLSLEPPGCIQENKEVSFHAFVSGNSSAHQYVW SFGDGSPNETQYGTALVTHSYVKIGEYHLSLLMSSEANKANFYKRICVQPVVTNVSWLPL RTHVKLGEESRFAVAAFPEFNYTYLWDFGALDSIAPVRGGKEMAFTFKSPGEYLVTVTVL NNISSINTSVSIEVQLSIGSLLISHNGEKGNNLSLHRNYDFKASSDSTNAIYIWEFGDGT RLNGTNVSHAYNSSGRFNISVTGKNQVSETKNEIFVVVLAPITGLSVNASCVNVPLNASV HFEAHFDQGDDVRYSWILCDRCTSLQGTHTMFYTFRSVGTFNVIVTAENDIGTAQSSIYI FVQRELEGLQIVADELVEGCCFATNRVLHLQASLKEGTNMTFSWNLLREHENHDRNFTGK TIDLNYSTPGPCEVLLKATNLLGQLAVNKTIEFLDPVRELVLETSPNPSAVNAMTTMTVS ASFGTDLHYRWWAGGELLTSDMSSIMYSFRNAGLKLVKVEVSNKISSEMVSKWISVQEPI SGLSFSATNVIENFVASGDNVSLCGETRMGSNISWMWLLPDSTTSSQRATSFVFLKTGIF NVALNASNDISRESYLRDFTVQDRIQGLELRASKNVAAVGENVEFTISVSSGTSVNFILS ISGDATVVLNNQTYVHQFTSVATYYVNLTAHNQVSSERKTLHIEVMEPVTKLTILDCCDA AIPVGVTRSYVASTPTRDPLTVLWTFDLHHGHKVPMVGKSVTYKPDEPGNLTIFLRAFNI LSGLNVTKFIQVQNSIRSAFLEAQPSDTFVNKTVRFHVGITPVSTPATYQWNFGDGSSTA VTTTPALSHIYFIPGHYVVRVNISNLVSWVTAQTQINISVLKCDEPEVQIIQAPRLAIWR YQPTLVEASVNLKGCALYGVEYLWEILTSPRCQDEDKKGPPPSKVRLPAEVNVRRLQLSV PKMSIYAGNYTLVFSLSYEGVPLRKAACLQLSVMSKKLVPIIEGGTYRVWSKTQDLHLSA EQSYDPNLDPENQSLLSYHWECVSTSKGPDHCSTLHFGLGPSDPVLGISGSELEVDVEYT FRLTVSKEGMTPESTTQTVWVQSGRIPMVSLECVSCKAQSRYEISQSSYVYLAGTCNNCH GSHRGHWTAKTRGNESLVLNLNTTTTGSDSMHLVVRQGVLRDGDSYKFSLHVTDDSMDRE GVAYIELHPNLPPAGGACSLWADGGALQVRTLVERVHFNCSGYADSDETESPLVYSLLVV RCYGSELPCEEFCVYKGTSPEHSAFLPPGFSSKQYRVSVSVMVEDHQGASVMALNKTVEV VLPSVPASFSSLPHWLSDMTHSSLRELLRQGDSQRVRELSLALITVLNEYEQGVSRRREH VTKAERQYRVSVRGNITRALTSLDLITVSDIQQTSAALAQCTVSREFVCEECQNSTLNKL ESMLEILQTDTKQGTVTPTEIADNILHIMGDLIHQVSQTSPAPEAEDRDSTSQQPLLLLE EHQHHPLRVAAKAYTLSSVLMRILMLGRVLNEEPLILRGAEIAAVGKRADPQSLHCYGKS NAPECRRFSIPRAFNASLGRAAGGALTPGANGEDGIVQLLFQVEPNPFPFNYVPNHTVST EVASMEFRTVNGTQIPISDLDESQAITVTVNNGSAAGLDANGLEAILAPAGAENVSHCSS VIVRVSTGNANRQAGIYVQLNFTVLDDSPETWELDPSITAYLHTSEWPNEYNSTDRKRIT LNMTRGPDLDHRHYTFFLSPEWHDTTREHFINVSTGCGAGDPALIRLEVAVFTSLCQYFS ESAGQWRTDGMVPLPDTSVGRAVCRTRHLTAFAASLFVPPDAVSFIIPERSVTRSLVVVL VCVIGLLCYAVAGAILRKLDQMDLRRASVVPLCGKDGLYKYEIQVKTGWAYGAGTTAHVG ISLHGSESRSGHRHLDSVGAFARNSLDIFHIATDASLASVLKIRVWHDNKGLSPAWLLQY VLVKDLQTGSSYFFLVEEWLSVDNEKTDGRVEIEVEASEEAELRQWPRLLSWELQRAVCE SHLWLSLWERPPRSPFTRLQRLTCGSLLMHLCMLANAVWYGTVAYGHSSTPVSHLVSVNV ETVWAGLVSCLLVYPVYLLVFCLFRLSRSKVSVEQLPPQVDQESLEIDDFLDNSLTGSSF LMLNGIPGETYSEETNIDLPTPSTKSLQRWSIPDCDWPDVLTDPSVEMGPVFPPRLKRGQ GSRHLGVDIAFSPDEDDTVCDNSHRNKYFSSSDEDLIKRILADGQLLSQTDSDVGDLSSI FGDKTEVILLQKMNEPVPCAAFRRDPPKTAFTSRTVVMDVCKPRPLPPLCGLAALWASWA WLILSASLSMWLGRSFSEGVALMWLISSIVSFLSSFLILEPLKVLLEAVYFSLVAGRLRA EEQDVLVDCPRVERVVQRIPRVRPPQGFALSQAREEARKVRLLHTMLKGFLLYMLFLLVV LLLNYSDSTKDAHRLRLHTQLQDHFLTERFNNISSREDVWAWLSDSLLPRLLDGRVLMEK TGSLLIGRPRLRQLRAQPECPVSGYFPASSWFGCAPAGWAESASGLVQNWSISTAQSSGV WHWGQVSVYSSAGFVQDLSRKMQDSRALVKQLNTHRWLDPLTRALFVEFPVYNINTDLLA VFSFLLEFPVSERAQLSLDLKTCSLHMLSHGMDLPLFLTLLLLVFVIYFAVREGVIVRKQ GLGYFLRLWNIASVCSLLLAICVVSLHLSRSVLSARQWGSFLQQQDTFTDFFPLAQQNQV LTQLSAALLFLLVLKASHQLRFMREWGVFGRTLRRSFWEMLTVAITLLVFLLAYSHTGHL IFHSVMEGYGTVSSTFLKLLGSSGRGLLSWRPDSGSSPCSASCFIFHISFTLLRLVLLWL LVSALLRNYRRARAELYRPAVDLQDYEMVELFLRRLKMWMGLSRAKEFRHKVRFEGMELP PSRSSSTSDCKSLCLPPLDTPEAPPSPDSVDGGSEASWRPTSSSPCSLAEAPGLGLGLTL GLGVIVGGQGWKERAEMEATLRRILPAFDALLLQLDRVTHATEELYRTECRLERLLRKSR GRGRGIRRHRSLESAGQKRHGYKEADRNTQVAEISKSPSITGMSASVSERNLHKRDGRSR KSGNFSQITSGLPTSLNKVDSSPHRTDSLQKTQEILSTVVVEVSKTEKDPDKASPPEEDS SPPRVQKADTASHKVKGTSKVDPNFQRDSEVVGCANKPAPTPVPTPTSTPSTAPVSAITT PVPIPRSHEWVPPSNSENLPSSVFRHPAHTTTNPTRKRKHKPPPLKNKVHPNTDRPISGH PKP NT seq 13872 nt NT seq  +upstreamnt  +downstreamnt atgccttgtagaaatggacagattgtgtttaagcgaaaacatggcgtctgtctcccaaag tttggattattttccagtctgctctttgcactcttttgcctcgaggcgcgctcgggtgtc acggcggacgggggagcgtgcagcccgtgcccggggaactgctcgtgcacggcggtggga ccccaaaacttgtgcgtggttaattgttccaacatcggactggatcaggcccccgcggcg tccggcctgcccaccgaaacacacactctagatctgtccagaaaccacattccctctgtg gattggagcctctttgatcacctcaccgccctcaaggagctgtatcttcagagcaatcgt ctggtcactcttcctcacgggatcttcggctgtgggccgttaactgtgctagatttgagc aacaaccagatcaccaccatcgaggaacgaacatgtgataatttatttaatttaacgaca atagatctgagctcgaacccgttcgtctgcgactgtaagctggtgcggttggtcggctgg ttgcaggaaaagggcgttcgagtgaagcgacccaactctatgctctgtgaccgtccaccg gaagtgaaaaaccagcccctgctcaacgtcagtgtgcacacctgcggcctgacgtacgcg ggctgcctggaggacgaggagcacgtggcgggtgtggagctggtcatcttctcgtcctcc actcccgggccgttctcgcgggaggagtgcaactcgaagtgtttccatgagaaccagctg tacggcgggctgggtcagcagagggagtgtctgtgcagcaccaactccgagcccaaccac atcagcgagtcgcagtgttcggccgcctgcgccaacccgcaggtcatgaagaagtgtcgc tggacggtggcgcacgacgtgtttcaggtgaatttctccgcctctcttccttcccgtcgc gtgtccgttcactccgaggccgtcctgtctgtcacctcctccgtcttccccgcctctctc tcatgggacttcggtgacctttcaccccgggtcaacagctccacgcccaacaccacggcg aggcacaagtacggggtcccgggacgctaccaggctcaagtgagtctctcggcgggtcac caggagatcgtggctcaggggggcgtgagcgtggatctgccgccccgactcgagctccac tgccctgcactcgtagtggccaatcagagcctggaggcggagctctctctggtcaactgg ggcggagtgggcgtgaccgtggactggaggatccagaaggatgggagagagatagcaaaa gcggagccgctgtgtttgccagatgcgctccatcacacggactcgtcccgctgtttcctc ttggtgttggaggaagtcagctggtcggacgcacgtcgggattgctcggcccgtggaggg gagctcgcagtggtgcattcccaaaccgtccgggacctcctggcccctcggatcacacat gagcgtggcgtgtggttgggcttgagcgatcagtattctccacgagtcctgcgctgggtg gacggttctgaggtccggtcgggggatgagggttcgagggaccgggccactctgcagcct ggaaatgtgtgtgtgtcactggacgccagcggccagcccagctcacactcctgcaccgcc aaacgagcttttgtctgccagttcacacggcaagtgcgtgttcctgatgctggcgtctat acggtgggaaccgccgtgtttaacacacacagtcctctgaggagtccgactgcgacacac acatctgtgcccaacacacccgccaagagtgtggagctgctgctgttccctggattgagt ttcctgaacgctggacgcctgtcgtctgtggatctgaacacacactctctgagcgcagac actcagctgaggcttcaggtgtaccgaccgaagtgccagagattcacacgcacgctgctg ccaggttgtggtgacctctgcgcccccatcactgtctgccaggccccggacgagtggatc aacgacacatccgtccgagccgagcccacgccgtgcccagcgggacgccagtactgtccg tacgccgagcagtgtctgccgctgtccagcccgtgccatcctggcgcttgtgtcaactgt tctggtgtcagtcccctgccggcgggcactcagtaccccgattacagcctggtcggggag gtgctggtcaccctgccggccggacctccctccaacgtcctggtccaggaggagatcgag gacctgctggtttcccccggggacttcatcgcccttcagcacgacgccggaccctcaggc ctcctccagtgctcctccgaaccctcctccccgtggaagcagagcgtgctcatccagaac cgctcggattggtgggatgcgaacgagacgctgctagcggacgctgagggaagttgggag gagggtgtggtttgtcagatgagggtgttgtacgtgggacagaacgacacccggctgcag ggtcccttcctccgttctggactccctcagtctggcgagtacagtttggaagtgacgtcc aacgataaggactttcccgtcaccgcatcttgtccgattcgagccgtcccaccattggcg cccaccgtgatccatcctatcaatcacagcgggaccgtgtacttcctccccaatcagacg tggattctcgtggcggtccgctcgcagcacgacgcctcgatcgagcgggagggcggcaac gcgaccgtagctttccgcagctcgtgtccgcagcacctggtggcgaaagtggccgaatgc agaaggcccggcccgttcaacgacaccatgttcgcgtgggtcgacctccagctcgggtcc acaccgggacagaccgccgtagtgcttcgtgtcaagagcgaagttaccgaagcatcgctg cagattgaagcgagggtgcaagagcgactccggggcctggttgtgcatccgcatcctgcg cacagagtcctcatggagtccatagtgagttacgtggcgtccgtggaggaagggtcggac ccgtcgttcaaatggacagtggatgataacccgaacttcacgtactacagcagcaattta aacatcatctaccagattgcaggagtttacaaactcgtggtaacggcgatgaaccaggtt agcatgctgagtgagctcttcaacgtgacggtggaccccatgaacccgatgactgtcccc gccgtccatggagtccccagaatcgtgcagcagggtctgtccctgaacctctctgcgtct gtgaagatagacatggcggtgaacgtcaccttctggtggtggtttggagatggagggaac cgtacacatcagtttaagcccccttataataactcctacaataaccaggtggtgattcgt gaccatgtggaatatatttatgcacagccaggggagtataccctaatgctctctgcttcc aaccgctacgagaacaagacatgcaaggtcgacgtatacgtcttcagcatcctgacaagt gtgcgaatcgaaatatacccaccactcctacgtgccgaaaaaccagctgactttgaggcc caccccttaccgtctccctacggcatcatctacacctggaacttcggtgacaattcgagt atccagcagggacgtgaacgcagggttcctcacgcgtacgctcacagcggcgtctacaac atctgcgtgatcgtgaacaacaccattagctggacgggcacatgtgcggaagttaccgtc tacgaggacgttaagggcttggaggtggcgtcatcggctcccaccgagcgcaacacgcgc accgtcgtcacagcaagtctagaagcaggtaacaacgtaacatggagctttgacatgggt gatggaacggtgttcacgggtgtggagccacaagttgaatatagctacaggaaagatgga aactacacggttaacgtcaccgcgaagaacgccgtgagctctcagtgggtaaccttacct gttgaggtgtttgtgctacaagtgttgtcgctagaacctcccgggtgcattcaggaaaac aaagaggtcagtttccatgcattcgtgtcggggaactcgtcagcgcatcaatacgtgtgg agttttggggacggaagccccaacgagactcagtatggaacggcgctggtaacgcactcg tatgttaagattggagagtaccatctctccctgcttatgtcaagcgaagccaacaaggcc aatttttacaaaaggatctgcgtccaacctgtagttacaaatgtgtcttggcttcctctg agaacacacgtgaagctcggcgaggagagtagatttgcagtagctgccttccctgaattt aactacacgtacctgtgggattttggggcacttgactcgatagctcctgttcggggaggg aaggagatggcttttactttcaagagtcctggggaatatctggtaacagtgaccgtgctc aacaatatctcctccatcaatacctcagtttcaattgaggtacagctatccattgggtct ttgctgatcagtcataatggagagaaaggaaacaatctgtctttacaccgaaactatgat tttaaagcatcctcagactcgacgaatgccatctacatctgggaatttggagacgggact cgactaaatggaacaaacgtatcacatgcttacaattcttcaggcaggttcaacatcagt gtcacaggcaagaatcaagtgagtgagaccaaaaatgagattttcgttgtggtcttggca ccaatcacagggctgtcagtaaatgccagctgtgtcaatgtccctttgaatgcttctgtc cactttgaggcacacttcgaccaaggtgatgacgtccggtactcttggattctttgtgac cggtgcacatctctccaaggcactcacacaatgttctacacgtttcgctccgttgggact ttcaatgttattgttaccgcagagaatgacatcggcactgctcagtccagcatttatatc tttgtgcagcgtgagttggagggcttgcagatagtggctgatgaacttgttgaaggatgc tgttttgcaaccaatcgcgtcctccacttacaagcctcgttaaaagagggcaccaacatg accttcagctggaaccttctgagggaacatgaaaaccatgatcgtaacttcacgggcaag accatagacctcaattactccaccccgggtccttgtgaggtgcttctcaaggcaaccaac ttgcttggccagctggctgtgaacaaaactattgagtttctggatcctgtgagggagctt gtcctcgagacttcaccaaacccttctgcagtaaacgccatgacgactatgacggtatct gcaagttttgggacggatctccattacagatggtgggcaggtggtgagctgttaacatct gacatgtcctccataatgtacagtttcagaaacgcaggtttgaaactggttaaagtggag gtttccaacaaaatcagctctgaaatggtctcaaagtggatcagcgttcaagaaccgatc tctggattgagtttcagtgccacaaatgttatagagaactttgtagcctcgggggacaat gtttctctgtgtggagaaacacggatgggatccaacatttcatggatgtggctattgcca gacagcacaacatcaagccagcgtgccacctccttcgtcttcctcaaaacgggaatcttc aatgtcgctttgaatgcctccaatgacatcagtagagaatcgtacttgcgcgactttaca gtccaagaccgtatccagggtctggagctcagggccagcaaaaatgtcgccgcggttggt gaaaatgttgagtttacaatctctgtctcgtctggaacctctgttaacttcatcctgagc attagtggtgacgcaactgttgtcctaaacaatcaaacgtacgtccaccagttcaccagt gtggccacgtactacgtcaaccttactgcccacaatcaagtgagttcagaacgaaagact ctgcacattgaagtgatggagcctgtgaccaagttgaccatactggactgctgtgatgcc gctatacctgtcggagtaactaggtcttatgtggcaagcactccaacacgggacccactg actgtcctgtggaccttcgaccttcatcatggtcacaaggttcccatggttggcaagtcg gtgacatataaaccagatgagccaggcaatctgaccatattcctaagagcattcaatatc ctgagcggtcttaatgtgaccaagtttatacaagttcagaacagtatcaggtcagccttc ttggaagctcaaccaagtgacacctttgtaaacaagacggtccgtttccatgtgggaatc actcctgtttccactccagcaacatatcagtggaactttggggatggttcttcaaccgct gtcacaaccacacctgcccttagccatatctacttcattcctggtcactatgtggtgcga gttaacatctctaaccttgtgagctgggttacagcacagactcagatcaacatctctgtc ctgaagtgtgacgaaccagaagttcagatcattcaagctccacgacttgcaatctggcgg taccagccaaccttggtagaggccagtgtgaacttaaaaggctgtgccctctatggagta gagtacctttgggagatcctcacctcccctcgctgtcaggatgaggacaagaaaggtccg ccgccatccaaggtccgtctccccgcagaagtcaacgtccggagactccagctttcagtg cccaagatgtcgatttacgctgggaactacactctagttttttctctgtcttatgaggga gtgccactacgcaaagcagcatgtctccaactttcggtgatgtccaaaaaattggtgccc atcattgaaggtggcacctaccgagtgtggtctaaaactcaggatttgcatttgagcgca gagcaatcctacgaccccaatctggatccggagaaccagtccctgctcagctaccactgg gaatgtgtgagcacctcaaagggtccagatcactgttccactttgcatttcgggttgggt ccgagcgacccggttctgggaatctctggctccgaactggaggtggacgttgagtatacc ttccgcctgaccgtcagtaaagaaggcatgaccccggagtccacgacccaaacggtgtgg gtgcagagcggccggatccccatggtgtcgctggagtgtgtgtcctgcaaagctcagtcc cgctacgagatcagtcagagctcctacgtgtacttggccggcacctgcaataactgccac ggctcacacagagggcattggacggcgaagacccgtggaaacgagtcgctggttctgaac ctgaacaccaccaccaccggcagcgacagcatgcacctggtcgtgagacagggcgtcctc cgggacggagactcctacaagtttagcctccatgtgacggacgacagcatggaccgcgag ggcgtggcctacatcgagctccacccgaacctgccgccagccgggggggcgtgctcactg tgggccgacgggggcgcgcttcaggtgcgcacgctagtggagagagtgcacttcaactgc tcaggttacgcggactcggacgagacggagtcgccgctggtctacagtctgctggtggtg cgctgctatgggtctgagctgccctgcgaggagttctgtgtgtataaaggcacgagtcca gaacattcggccttcctgccgcccggcttcagctcgaagcagtacagagtgtctgtgtcc gtgatggtggaggaccaccagggggcgtcagtcatggccctcaacaagacggtggaggtg gtgctgccgtcggtcccggcgagcttcagttctctcccgcattggctgagcgacatgacc cactccagcctcagagaactgctccgacagggagactcacagagagtccgagagctctcg ctcgccctcatcactgtcctcaatgagtatgagcagggtgtgtcccgcaggcgtgagcat gtgactaaggcggagcgtcagtatcgagtgagcgtcagaggaaacatcaccagagcgctg acatcactggacctcatcaccgtcagtgacatccagcagacgtcagcggcgctcgcccag tgcacggtgagtcgagagtttgtgtgtgaagagtgtcagaacagcactctgaacaaactg gagtcgatgttagagatcctgcagacagacactaaacagggcacagtcactcccactgag atcgcagacaacatcctccatatcatgggtgacctgatccaccaggtgagccagacctct ccggcgccggaggccgaggaccgcgacagcacttcccagcagcctctgctcctcctagag gagcaccagcatcacccgctgcgagtggcggctaaagcctacaccctgtcctccgtcctc atgaggatcctgatgctgggccgcgtcctgaacgaggagcccctgatcctccgcggggcc gagatcgcagccgtcgggaagcgcgccgatcctcaaagcctgcactgctacggcaagagt aacgcgcccgagtgccggcgcttctccatcccgcgagcgttcaacgctagtctgggacgg gcagcagggggcgccctcacgccaggagccaacggcgaggacggcatcgtgcaactgctc ttccaagtggagccaaatccattcccgtttaattatgtccccaatcacaccgtgtccaca gaggtggcgtccatggagtttcgcacggtgaacggcacgcagattcccatctcggatctg gacgagagccaggccataacggtcaccgttaataacggaagcgcggccgggctggacgct aacggattggaggccatcttggcgccggcgggagccgagaacgtcagtcactgcagttcg gtcatcgtgagggtgagcacggggaacgccaacagacaggcgggaatctacgtccaactc aacttcaccgtactggacgattctccagaaacgtgggaattggatccatcgatcacggcc tatctacacacttctgagtggcccaatgaatacaacagcactgacaggaaacgcatcacg ctcaatatgacgcgggggccagacctggaccaccgacactacactttcttcctgtctcca gaatggcacgacaccacgcgcgagcacttcataaacgtgtccacgggctgcggcgcgggt gacccggctctgatccggctggaggtggctgtgttcacgtctctgtgccagtatttcagc gagagtgcgggacagtggcgcacggacgggatggttcctctgcccgacaccagcgtgggc cgagccgtgtgtcgcacgcgtcacctcaccgcgttcgccgccagcctgttcgtcccgccc gacgccgtctccttcatcattcccgagcgctcagtgactcgcagtctggtggtggtgctg gtgtgtgtgatcggactgctgtgttacgctgtggccggagctatactgcggaagctggat cagatggacctgagacgggcctctgtggtgccgctgtgtgggaaggacggtctctacaag tacgagatccaggtcaagaccggctgggcctacggagcaggcaccacggctcacgttggc atcagtcttcacggcagcgagagtcgcagtgggcacagacacctggacagcgtcggtgcg ttcgctcggaacagtctggacatcttccacatcgccacagacgccagcctggccagcgtg ctcaagatccgagtctggcacgacaacaaaggtctgtctcccgcttggctgctccagtat gtcctggtgaaggacttgcagacgggcagcagttacttcttcctggtcgaagaatggctc tcggtcgacaacgagaaaacggacggccgggtggagatagaggtggaagcctccgaggag gcggagctccgccaatggccgcggctgctgtcctgggagctgcagagagcggtgtgtgag agtcacctgtggctgtctctctgggaacggcccccgaggagccccttcacccgtctccag cggctcacctgtggctcgctgctcatgcacctctgcatgctggccaacgccgtgtggtac ggcaccgtcgcttacgggcacagctctacgccggtgtctcatctggtctcggtgaatgtg gagactgtgtgggcggggcttgtgagctgtctcctggtgtaccctgtgtacctgctcgtc ttctgcctcttcagactcagccgcagtaaggtgtctgtggagcagcttcctcctcaggtg gaccaggagtctctggagatcgacgacttcctggataactccctgacaggaagctctttc ctgatgctgaatgggattcctggagagacgtactcagaagagaccaacattgacttgccg actccttccactaagagtctccagaggtggagtattccggactgtgattggccagacgtg ttgacggacccgtcagtggagatggggccggtgtttcccccccgcctcaagagaggtcag ggcagcagacacctgggggtggacatcgccttcagcccggacgaggacgacaccgtgtgt gacaacagccacaggaacaaatacttctcctcctcagatgaggatctaatcaagcgcatc ctggccgatggacagttgctgtctcagacggacagtgacgtgggcgatctctccagtata tttggggataagacggaagtgattctgctgcagaagatgaatgaacctgtcccgtgtgcg gcctttagacgagacccacccaaaactgccttcacttcacgcacagtggtgatggatgtg tgtaagccaagaccacttcctcctctatgcggattggctgctctgtgggccagctgggcg tggcttatcctgtccgccagcctatcgatgtggctggggcggagcttcagcgagggcgtg gctctgatgtggctgatctccagcattgtcagcttcctgtcgtctttcctcattctggag ccgctgaaggtgctgttagaggctgtgtacttctctctggtggcggggcgtctgagagcc gaggagcaggacgtgctggtggactgtcctcgtgtggagcgggtcgttcagcggatccct cgggtccggccgccgcagggcttcgctctctcacaggccagagaagaagcgcgtaaagtc cgcctgctacacaccatgctgaagggtttcctgctctacatgctgttcctgctggtggtt ttactgctcaactactcagactcgaccaaagacgcccaccgcctgcgacttcacactcaa ctgcaggatcacttcctcacagagcgcttcaacaacatcagcagtcgtgaggatgtgtgg gcgtggctctcggactccctgttaccacggttactggatgggcgggtcctgatggagaag acgggaagcctgctgattggtcgacctcgtctccgacagctgagagcgcagccagaatgc cccgtcagtggctatttcccagcatcctcgtggtttgggtgcgccccagccgggtgggcg gagtcagcctcgggattggtgcagaactggagtatcagcacagctcagagcagcggtgtg tggcactgggggcaggtgtctgtctacagcagtgctggattcgtacaggatctcagcaga aagatgcaggactccagagctcttgtcaaacaactcaacacacaccggtggctcgacccg ctgacgagggctctgttcgtggagtttcccgtctataacatcaacactgatctgttggcc gtcttctcgttcctgctggagttccctgtatcggagcgcgctcagttgagtctggacctc aaaacctgcagcctccacatgctcagtcacggcatggacctgcccctgttcctcacgctc ctcctgctggtcttcgtgatctatttcgctgtccgtgagggcgtgattgtccggaaacag gggcttggctacttcctgcgcttgtggaatatagcaagtgtttgcagtctgctattggcg atttgtgtcgtctctttacacctgagtcgctccgttctgtccgcccgccagtggggctca ttcctacaacaacaggacacattcacagacttctttcctctggcccaacagaaccaggtt ttgacccaactgagcgcggctttgctcttcctgctggtgctcaaggcttcgcaccaactg cgcttcatgagagaatggggggttttcgggaggacgctgaggagatctttctgggagatg ctgacggttgccatcactcttctcgtgttcctgttggcatactcacacactggacacttg attttccactctgtcatggagggctacggaactgttagctctactttcttgaagttgctt ggctctagtgggcgtggactgttgtcatggcgaccagacagtggctcctccccatgttct gcttcctgcttcatcttccacattagctttactctactcagactcgttttgctgtggctt ttggtctcggctttgctaaggaactatcgtcgggcaagggcggaactgtaccgtccagcc gttgacctacaggactatgagatggtggagttgttcctgcgacgcctcaaaatgtggatg gggctcagccgtgctaaagagttccggcacaaggtgcgatttgaaggtatggagctcccg ccttcacgttcctcttcaacaagtgactgcaagtccttgtgtcttcctcctctggacact ccagaggctcccccatctcccgacagtgttgatggaggatctgaggcctcttggcggccc acttccagcagcccttgcagtctggctgaagccccgggtctgggacttggccttacctta ggccttggggtgatagttggaggccaaggctggaaagagagagccgagatggaggcaacg ctccgcagaatcctcccagctttcgatgctttgcttcttcagctggaccgggtcacccat gccacagaggaattgtatcgaacagagtgccgtctagagaggctgctgaggaagagcaga ggacggggcagagggatacgccgccacagaagtctggagtctgcgggacagaagagacat ggatacaaggaggcagacaggaacacacaagtggcagagattagcaaaagtccctcgata actggaatgagtgcatccgtgtccgagagaaatcttcacaagagagacggaaggtcaagg aaatcaggcaacttctcacaaatcaccagtggccttcccacaagtctcaataaggtagac tccagtccccacaggaccgatagtctccaaaagactcaagaaattctcagcaccgtggtg gtagaagtcagcaagacagagaaagaccctgacaaagcaagtccccctgaggaggacagt agtccacccagagtccaaaaagctgacacggcttctcataaagtaaaaggaacctccaag gttgacccaaacttccaaagagactctgaggttgttggctgtgccaacaaacctgcccct acccccgttcccactccaacgtctactccctcaactgctccggtttctgcaataactacc ccagtaccgatccctcgctcccatgagtgggttcctccaagcaacagcgagaaccttccc tccagtgtattccggcaccctgcacacactactacgaatcccacccgcaaacgcaagcac aaacctccccctcttaaaaacaaggtgcaccccaacacagacagaccaatctcagggcat cccaaaccttga

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