Pimephales promelas (fathead minnow): 120493581 Help Entry 120493581         CDS       T08155                                  Symbol hmcn1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism pprm  Pimephales promelas (fathead minnow) Brite KEGG Orthology (KO) [BR:pprm00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:pprm04990]     120493581 (hmcn1) Domain-containing proteins not elsewhere classified [BR:pprm04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    120493581 (hmcn1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 EGF_CA VWA_4 G2F cEGF C2-set_3 V-set_CD47 TSP1_spondin Ig_6 C1-set Ig_C17orf99 GBD_Hemicentin Izumo-Ig FXa_inhibition TSP1_CFP_C Herpes_gE EGF_3 EGF TSP1_ADAMTS Coilin_N TSP1_CCN VWA7_4 VWA_2 hEGF Fibulin_C Motif Other DBs NCBI-GeneID:  120493581 NCBI-ProteinID:  XP_039548203 LinkDB All DBs Position Unknown AA seq 5622 aa AA seqDB search MDLRLSPFFLGLIIVLNVLSAAQDTNEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKI LETSLSRPQRPLYNFALVPFHDPEIGPITITTDPKKFQDELRELYVQGGGDCPEMSIGAI KIALEISLPGSYIYVFTDARSKDYKLTHDVLQLIQQKQSQVVFVLTGDCDDRSHIGYKVY EEIASTSSGQVFHLDKKQVNEVLKWVEEAVQSSKVHLLSTDHQNGLANTWRIPFDPSLKE VTVALSGPAPNIEIRNSQGKLIGMKEGLSELLHIPNSAKVLNLKDPAPGMWTIKTSSEGR HSVRISGLSTIDFRAGFSRKQTLDFKITSSRPVQGIPTFILLNTTGLSPPARADRMELLS ITGDVMKTLPIRYFPERRPYSIWNITEFVPPKEAFFLRVTGYDSDGFLFQRVSSVSYSSI VPDAPKVSMPTHTPGYYLQKGAITCSVDSLIPYTLRFTREGLRVGVDQLFRESANASWGI AQVSLKDEGFYECIAISSAGTGRAQTFLDVSEPPPAITVPSNVTAYPGANVVLTCLVTST VHFNLTWQRGDVDAKLDHRIRVTANQSLEIQRVSPNDVGWYTCIAANEGGVSASRVYLNV QEPPVVTVDPRNQTFRTGQEVWIRCSAKGYPSPMVVWIHNDMFIMGSSRHRMTTDGTLVI RNMGPKDAGTYGCLASNVAGTDTQTAFVSYVESPQVTVPHSDLLIGLGQTTIMECRVTGV PHPDVLWYKDDIQLKPSPVLSIDPQRSTLSIQQTLDTHAGEYTCVAVNSAGSAQGYITLD VGSTPQFTQKPSDLSADIGTNVTLPCHARGHPEPQLSWRRDDNVSLFSQRRGPSTVTKKI DGGLFITNLWVEDEATYVCEAQNHFGKIQAKAKVTVTGLVSPLIALSPTVVSVIEDQQVT LPCVVLAGNPLPERHWLHDNGLVTSNPYVTVRRDGSLHIERVSQQDGGQYTCLAENVVGS SNRTTILNVYVMPTIQHGPQVFSTIEGAPISLPCRAHGVPKPDITWSKRGELLDLTGSVF SLFEDGSLHIISPSGEESGEFVCTATNAAGYSSRKVQLTVYVKPRPSGVEMLNNSDKLLE ISVTVGEDVILPCDVQSIPPPIITWAKDKQLISPFSPRHIQQPSGSLRITETRVTDSGMY RCVATNIAGNFTQTVKLRVLVPPSIRAGPRAMKVLVGHAIDLPCVAQGVPEPSVSWLKDG ATLLDGSHYRISDGALTLNQVGLIDEGVYTCVASSIAGQDEAIIQLHVQVPPVVEVSEPP FNSPLQERVANQQIAFPCPAKGTPEPVIKWSRNGQELTGNEPGVSILEDGTLLILASVSP LDNGEYTCVAVNDAGTTEKKYQLKVNVPPDIRDNGLLTNVSVVMDQPTNLVCDVTGTPVP VITWYKDGVVVVSSSDVQILQKGKTLKLLKATVADAGRYSCKAINIAGSTDRDFYLDVLV PPTIIGTVGSRDLSALLNQEIILECRVKGDPFPTIQWYKDRKQVFLGDPNIEVLNRGQQL KIKSARLGDQARYQCSATNAAGKQSKDFNLSIFVPPSIKGGNTSSEVTVLLDNVVTLECE VRGVPLPAITWYKNREVILSSRQTQYVDRGQFLKIARAQISDAGQYTCKVTSVAGTAEKS YDLDVYVPPSITASSDGPTDMKVVLSKSLILKCEAEGHPPPSLTWLKDGSPVAAKENLRV LEQGRKIEILSALPSDAGRYVCVATSVAGAREIKYDVSVLVPPVVDGASDTTDATVILNN ILELDCYATGTPTPTITWLKDGVPVRQGEGVRITSNGRRLVISRAQVSDTALFHCVATNE AGEQEREFKVSVHVSPAIRSTGPAERSVVLHTSISLQCVVSGIPPPSITWLKDGRPVDTT QEFLKLESTGRVLHIKKARLEDAGKYTCVATNAAGEAQQHIRLSVHEPPSIQYAGETLNE TILAGFQIQLKCKATGSPLPAVTWYKDSRPLTNAAGVNILSRGQVLEIDRAQVSDAGLYK CVAINVAGSTELTYSLQVYVPPSISSKGGMKTVVVNEPVRLECEASGVPMPSLTWLKEGR PVSSFSDGVQVLSSGRVLSFVSAQVSDTGHYTCVAVNAGGEQHREYDLRVYVPPNIMGEE VNKTVLIGLSVQLHCQSDAIPPPALSWRKDGRPLYRKPGLSLSEDGSFLKITSAQVQDTG RYTCEAINVAGKTEKHYNLNVWVPPSIRGSDEVSSLTVIEGSLMTLVCESSGIPPPHLTW KKNGSELKGDSRVRVLSGGRQLQISSAEKADAFSYTCLATSAAGSAMKEYNLRVYVRPSI SSSNQDEETVTRGGDITLKCEADGVPRPAISWMKDGRPLSTGSRAQILNEGQLLRIQDAQ VADTGRYTCIAVNVAGQADRKYDVNIHVPPTIIGQTQMPENVSVVVKNPVVLTCEASGMP PPAITWLKDGQLISMSSSVRVIAGGRGLRLMHAASEDAGRYTCIVSNSAGEERKNFDLNV LVPPSIVNEGTVEDLKVKEKQNIILACEVTGYPVPEITWLKDGQPLTSDARMQVMSNGRF LQISGSQVSDTGRYSCLASNSAGDRSRHFNLNVLVSPTIAGSGPEGSAEEVTVTLNSPTS LVCEAQSYPPAIITWLKDGTPFESSRNVRVLPGGRTLQILNAKEEDAGRYTCVATNEAGE TLKNYEVKVFVPPVINKNDIPGESLAPKEVKIKVNNTLTLECEAQAIPTPTLVWYKDGQI LKADGHLSITANGRIVQIKHTQVSDTGRYTCVATNIAGEDEKDFDVNIQVPPSFRGFGDS DSGLGNNGDVKDVILNNPFSLYCETNAVPPPVLTWYKDGHLLTSNDKILILPGGRVLQIP RAQAKDSGRYTCVAVNEAGEDSIQYDVRVLLPPSIRGADGDLPDEVTVLVNKTTLLECQV DGSPTPKISWIKDSQPLTPDNTHRLLSNGRTLQILNAQVTDTGRYVCVAQNLAGTAEKSF NLHVHVSPSIVGIREENVTVVVNNFISLNCEATGLPPPTLSWFKDRRPLQASTNALIMPG GRTLQILKAKMSDGGKYSCVAMNPAGEAQKIIYLTVYVPPSIRHSSGDLPVVLNVLVGKS VTLECESNAVPPPIITWYKNGRPITETAHLRILADGQMLELRETELSDTGQYICKATNVA GQVDKNFHLNIHVPPRLDGPAVERVVETIGNPVTFACDASGIPPPSLTWLKNGKVIENSE SVDMHILSGGSKLQIARSQLSDSGTYTCLASNVEGKARKNYQLIMQVPPIIVGSELPSEM SVLLNDSIQLVCRAEGTPTPEIQWLKDGKTLSRTAQKNIKISTDGSTLTVTAIHTSDSGK YTCVATNQAGEEDRIFSLNVYVPPLIQGNGPAAKELTAVLDSSINIECVASGSPPPQLNW LKNSLPLPISSQIRLLSAGQVLRIARAQVSDGGSYTCVASNRAGVDNRHYNLQVYVPPSL DGAGSTDEVTVVRGNTASFICISDGMPSPIITWLRNGAAVPKDPHLSLLNQNSTLQISHV SINHTGRYTCTAHNQAGDASRHFSLKVLDPPRINGSGVPAEVSVVVNHVLELVCEADGIP LPTLTWLKDGRPLPQTDSIRLLRDGEVLRVASAQVENTGRYTCLATSPAGDDDKEFLVRV HVPPNIAGDTGVQDVLVLQNRQVTLECKSDAVPPPTLTWLKDGAPLKMSPRVRVLSSGRY LQINNAELRDGAQYTCVASNVAGETRRHFNLSVNVPPTIKDGPQSVLVNIHQPVVLECVV NGVPTPRITWRKHGSILAGNNPRYRFGEDGSLHIFSAQVTDTGRYLCMATNQAGTERKRV DLQVYVPPSIAEGPTNITVTVNVQTTLSCEATGIPKPSVSWTKNTQALNTDQNQNMYRLL SSGSLVVIAPTVEDTALYKCVVSNEAGQESREIQLTVHVPPSIADEATELVVSRLSPVVI GCTASGVPHPVLYWSKDGLRLAKKGEGYTILPSGPLEITAADLSHSGRYSCVAKNAAGTA HRHVQLTVHEHPVIQSHPSTLDVILNNHVTLPCRAMGSPHPTITWQKEGINIFTTGGGFT VLPNGGLQISKARVEDSGTYMCVAQNPAGTALGKTKLRVQVPPVITSDIKVYTVALDASV TLQCHSEGFPTPSITWYKDGQPLSESMHQRVLSTGALQIAFSQPGDTGRYTCTAANVAGT TSLEMSLTVHIPPSIRVGESEVSVVENTQALLTCVADGVPQPTITWEKDDIALTDTTGEY TILPTGELLIDTAQPEDSGSYTCVGTNSVGQDSHTIDLSIHTHPVFTELLGDVALNKGER LLLACGVTGIPSPKITWAFNNNIIPAQYGHINGHSELVIERVSKDDSGTYSCMAENSVGS IKSLGFVFVKEPPIIDGDVHSNRIEPLGGNAILDCEVRGDPLPTIQWSKKGINVQISNRI RQLDNGSLAIYGTVSEDAGYYMCVATNDAGVVERTVTLTLQSSPTITVEPIETVVDAGST VMLNCQAEGEPVPVIEWSRQGRPLLGNEHITTLNNGSLRLSSAQKEDTAEYECVARNLLG SVLVRVTLTVRVHGGFSEWMEWGACSVSCGAGVQRRLRQCNNPIPANGGRHCIGSARETR SCQGKPCPVDGNWSEWSSWEECSRSCGQGNRTRVRTCSNPPAQHGGRACEGKAVEAIMCS IRPCPVAGNWGAWLPWSPCSETCGKGMQTRLRLCNNPPPSFEGPSCEGPDSQTQVCNERN CPVDGKWSSWVSWGACSVSCGGGTRQRTRLCASPTPQHGGRQCEGNDIHIDFCHNEPCPI HGNWGPWNSWGSCSRTCNGGQMRRYRTCDNPRPANGGRACTGSDSQIQKCNAANCPVDGK WGSWESWGECSASCGGGERTRVRLCNNPSPSNSGRPCPGDSTQLSRCNIQPCPGGPQKAR GSIIGNINDVEFGIAILNATISSSPTGGRVIQATITNIPRSLGSAMRKLISILNPIYWTT AQELGEAVNGYTLTDGIFRRETQVEFATGEILRMTHVARGLDSDGALLLDIVVNGHILQL PSNADISLKDYTEDYIQTGPGQLYALSTRMFSIDRVSVPYSWNHTITYGPSRGKMPYLVQ TLHASAISALYRPLEEMLEFSIHATIAKGERSNQCPSGFQLNPAGPYCADENECVDGNPC SHACHNSIGTYYCSCPRGLAISADGRTCQDIDECSQGGHMCHDGQDCENTIGSYRCVMRC GRGFRRTADGLSCLDVNECQESNPCHQHCLNTIGSFRCACEPGYQLRNRRCIDINECKQR VCRSDQQCKNTRGGYTCIDLCPTGMTKGDNSTCIDIDECHDGTHQCRYNQICENTRGSYH CTCPRGYRSQGVGRPCLDINECELVPVPCAYQCVNSQGSYKCLCPPGLHLLGDGKSCAGL ERLPNYESFSYGYRTSQSSSDRSSYQQRYHSLTSQSYHSYVPIGGRHVANRPNNAPSRSR RDTNTCPPGFKAKNGQCLDINECEQRDTCQHECMNTPGSHRCLCPNGYRLMSNGKTCQDI DECLEQNIQCGANRMCFNMRGSYQCIDTPCPPNYQRDPTTGFCLKNCPPNDLECALSPYA LEYKLLSLPFGIAANQDLIRLVAYTQDGVIHPRTSFLVVDEDTTLPFALRDENLKGVLFT TRPLREPHTYRMKVRALSYSADGGIEYQTTFIVYIAVSAYPY NT seq 16869 nt NT seq  +upstreamnt  +downstreamnt atggacttgagactttcaccgttttttcttggtctgataatagttcttaacgttttatca gcagcacaggacacaaatgaagaaattcccgaaggagcgtctacattggcgtttgtgttt gatgtcacaggctccatgtacgatgatttagtgcaagttattgaaggagcatcgaagatt ttggaaacatccctcagtagaccccagagacctctgtacaacttcgctttggtgcctttt catgacccagagattggacccattacaataacaacagatccaaagaagttccaggatgag ctgcgggagctttacgtccagggaggtggagattgtccagagatgagtattggagccatt aagattgcccttgaaatctccctaccagggtcctatatttatgtgtttacggacgcccga tcaaaagactacaagttgacccatgacgttcttcagctcattcagcagaaacagtcacag gtagtgtttgtattgaccggtgactgtgatgaccgatcgcatatcggctataaggtgtat gaggagatcgcctctaccagctcaggacaggtattccatctcgacaagaaacaagtcaat gaggtgttgaaatgggtagaggaggccgtgcagtcctctaaggttcacttgctctcgact gatcaccaaaatgggcttgctaacacctggcggatcccctttgaccctagcctaaaggaa gtgaccgttgccttaagcggccctgctccgaacatcgaaatccgaaattctcagggaaaa cttatcgggatgaaggaaggtctgtctgagctccttcacatcccaaactctgccaaagtc ctcaacctcaaagacccagcgccaggaatgtggaccataaagacgtccagtgagggcaga cactcagtccgtatatcaggcctcagcaccatcgatttccgagcaggcttttcccgaaaa caaacgttggacttcaaaattacatccagcaggccagtccaaggaatccctaccttcatc ctgctaaacaccaccggtctttcccctcctgctcgtgctgaccgcatggaactcttgagc atcactggtgatgtaatgaagacactgcccattcgctacttccctgagcgacgcccttat agcatttggaatatcacagagtttgttcctcccaaagaggccttttttttgcgtgtcact ggctatgacagtgatggcttcctctttcagagagtgtccagtgtctcttactccagcatt gtgccagatgcgcccaaagttagcatgcccactcacactccgggttactacctgcagaag ggggctattacatgttctgtggatagcctgatcccctataccttgcgtttcactagggag ggactacgtgtaggtgtggaccaacttttcagggagtctgctaatgcatcatggggaatc gctcaggtgtccttgaaggacgagggcttttatgagtgcatcgccatcagcagtgccgga acaggacgggctcaaaccttccttgatgtttctgagcctcctcctgctatcacagtgccc tccaatgtgacagcgtatcctggtgcaaatgtcgttctgacatgtctggtcaccagcacg gtgcactttaacctgacttggcagagaggggacgtggatgcaaaattggaccatcgcata cgtgtcaccgccaaccagtccttggaaatccagcgagtcagtcctaatgatgtcggctgg tatacctgcatcgcagccaacgagggtggagtctccgcttctcgtgtgtacctcaatgtg caagagccaccagtggtgacggttgaccctcggaaccagacgttccgcaccgggcaggaa gtttggatcaggtgttcggccaaaggctacccctcgcccatggtagtgtggatacacaat gatatgttcattatgggctccagcaggcacagaatgaccactgatggcacactggtcatc aggaacatggggccaaaggatgctgggacatacggatgcttggcgagtaatgtggcagga actgacactcaaactgcttttgtcagctacgtcgagtctccacaggtgacagtccctcac tctgacctgctgattggtttaggacaaacaaccattatggagtgcagggtcacgggagtt ccacatcctgacgtcctgtggtacaaagatgacattcagctgaagccatctccagtttta agtatagaccctcagcgcagcactctgagcattcagcagactctggacacacatgcagga gagtacacatgtgtggcggtgaactccgccggatctgcacaggggtacatcacgctggat gtgggatctactcctcagttcacacaaaaaccatctgatctgtctgctgatatcggcaca aacgtcaccttgccgtgtcatgcaagaggccaccctgaacctcagctctcctggagacga gatgacaatgtctcactcttctctcagcgccgcggtcccagtactgtcactaaaaaaatt gatgggggccttttcatcaccaacctctgggtagaggatgaggccacctatgtgtgtgaa gctcaaaaccactttggcaaaatccaggccaaggccaaagtcactgtcactggactcgtg tctcctttgatagctctgagtcccacagtggtcagtgtgatagaggaccagcaggtcact ctcccctgtgtcgtactagctggaaacccacttcctgagagacattggctacacgacaat ggcctggttacatcaaatccatatgtgaccgtgagacgtgatggtagtctacatatagaa cgggtcagtcagcaggatggggggcaatacacctgtttggccgaaaacgtggtgggatct agcaaccgcaccaccatactcaacgtttacgtgatgcccactattcaacacggccctcaa gtattcagtaccattgaaggggcgcccatttctctgccatgtcgtgcacatggagtcccc aaaccagatatcacttggtctaagcgaggggagttgctggatctgactggcagtgtgttt tctctgtttgaggatggcagtcttcatattatctcccccagtggtgaagagtctggcgag tttgtgtgcacagccacgaatgctgctggatacagctccagaaaggtccagctcaccgtc tacgtgaagcccaggccaagtggtgtagagatgctgaataactcagacaagctgttggag atttcggtaacagtgggtgaagatgtcatcctgccatgtgacgtacagagcatacctcct ccaatcatcacctgggccaaagacaagcaactcatctcccctttctctcccagacatatt cagcagccatcaggctccttgaggatcacagaaacacgtgtgactgacagtggcatgtac cggtgtgtggctacaaacatagctggaaacttcactcagacagtcaaactccgcgttctg gttcctcccagcatccgagcaggtcctagagccatgaaagtgctggtgggacatgccata gacctgccctgtgtcgcacagggagtcccagaaccctctgtgtcctggctgaaggatggt gctactctgttggacgggtctcattacaggatctcagatggggctctgactctgaaccaa gtggggcttattgatgagggcgtctatacctgtgtggcttccagcatcgctgggcaagat gaagccatcattcagctccatgtacaagtccctcctgtggtggaggtatctgagccccct ttcaacagccctttacaggagagagtggctaaccagcagattgccttcccctgtcctgcc aaaggcactcctgagccagtaataaagtggtctaggaatggtcaggagttgacagggaat gagccaggtgtgtctattttagaggatggcacacttctaatcctagcctctgtgtcccct ctggataatggggagtacacttgcgtggctgtcaatgatgctggaacaacagagaaaaaa taccagcttaaggtcaatgtcccacctgatattagagacaatggcctgctgaccaatgtc tctgtagtgatggatcaaccgaccaatctggtgtgtgatgtcacaggcacacctgtacct gtcatcacctggtacaaagatggagtcgtggtggtttctagcagcgatgtgcagattctg cagaagggcaaaactcttaagcttttgaaagcgactgttgcagatgccggacgctacagc tgcaaggccatcaacattgctggaagcacagatagagacttttacttagatgtgttggtt cctcctacgatcattgggacagttgggtcacgtgacctctctgccttgcttaatcaagag atcattctggaatgcagggtcaaaggcgatccctttcccacaattcagtggtacaaagac aggaagcaagtgtttttgggtgaccccaatattgaagttttaaacagaggacagcagttg aagataaagagtgctcgcttaggtgaccaggctcgataccagtgtagcgccaccaacgct gcaggaaagcagtccaaagattttaacctcagtatctttgtcccacccagcattaaggga ggaaacacgtcttctgaagtgacagtactgctggataatgtggtgactctggagtgtgag gtacggggtgtgccactccctgccatcacatggtacaagaacagagaggtcattctgtcc agcagacagacccagtatgtggaccgagggcagttccttaagatcgcaagagctcaaata tcagatgctggacagtacacctgtaaagtcaccagtgtggctgggaccgctgagaaaagt tatgaccttgatgtctatgttcccccctccatcactgccagttctgatggtcccacagac atgaaggtcgtgctcagtaaatctctgattttgaaatgtgaagctgaaggtcaccctcct ccctcactgacctggctaaaggatggttcaccggtggctgctaaagagaacctgcgtgtt ctagagcagggtcgcaaaatcgaaatcctcagtgcacttccatctgatgctggtcgatat gtttgtgtagctaccagtgttgctggagcgagggagatcaaatatgacgtcagtgtctta gttcctcctgttgttgatggggcaagcgacaccacagatgccacggtcatcctcaacaat atcctagagctggactgctacgctacaggcacacctactccaactatcacgtggctgaag gatggcgtaccggtgaggcagggcgaaggggtgcggataacttcaaacggccgtcgattg gtcatctcgcgcgctcaggtgtctgatacagctctttttcactgtgtagcgaccaacgag gctggagaacaagagagagagtttaaagtgtctgtacatgtctccccagctattcgttct actggtccagctgagaggtcagtggtcctccacacatcaatcagccttcagtgtgtggtc agtggaattccccctcccagcattacatggctcaaagatggccgtcctgtggacacgaca caagaatttctgaagctggaatccactggcagggtattgcacataaagaaggccaggctg gaggatgctgggaaatatacgtgtgtggcaactaatgcggcaggcgaggcacaacagcac attcgcctcagtgtgcatgaacctcccagcatccagtatgctggagagacactcaatgaa accatccttgctggcttccaaattcagctgaagtgtaaggcaacaggaagtcctttgcca gctgtgacatggtataaagacagtcgtccattgacaaacgctgcaggtgttaacattctg agtagaggtcaggtgctggagattgaccgtgcgcaggtgtcagatgctggactctacaaa tgtgtggccatcaatgtggccggcagcactgagctcacatacagtctgcaggtctatgtt cccccctccatttcaagcaaaggaggaatgaaaacagtggtggtgaatgagccagtcagg ttagagtgtgaagcctcaggagttcccatgcccagcctcacctggcttaaagaaggcaga cctgtctccagcttctcagatggcgtccaggtattgtcaagtggcagggtgttgtcgttc gttagtgcgcaggtcagtgacacaggtcattacacctgtgtggctgtaaatgcaggtgga gaacagcacagagaatatgacctacgtgtgtacgtgccgcccaacatcatgggtgaggag gtaaacaaaactgttctgataggtctgtcagtgcagctgcattgtcagagcgatgccatc cctccacctgcactgagctggaggaaagatggacgaccgctatatagaaaaccaggactc agcctgtcagaagatggcagctttcttaagattaccagtgctcaggtccaggacacaggc aggtatacatgtgaggcaatcaatgtggcaggaaaaacggagaagcactataacctgaac gtgtgggttcctcccagtatccgtggatctgatgaggtgtcttctctgactgtgattgag ggcagcctcatgacacttgtttgtgagtccagtgggatccctcctccccatctcacctgg aagaaaaacggctcagagctaaagggagattcacgtgtacgtgttctttctggtggacgg cagctgcagatttccagtgctgagaaggcagatgctttctcttacacctgtctggcaaca agtgcagctggcagtgcgatgaaagagtacaatctgcgagtctacgttcgtccctccatc agctcctcaaatcaggatgaggagacagtgacgcgaggtggagatatcactctgaagtgt gaagcagatggggtccccagacctgccatatcatggatgaaagacggtagacccctgagc accggcagcagggctcaaatactcaacgagggccaacttttacgcatccaggatgctcaa gtggctgacactggacgatacacctgtatcgctgtcaatgtggcaggacaggctgacagg aaatatgacgtcaatattcatgttcctcccaccatcatcggtcagacgcagatgcccgag aatgtgagtgttgttgtgaagaacccggtcgttctcacctgtgaagcttctggaatgcca ccaccagccatcacgtggcttaaagacggccaactgatcagcatgtctagctctgttcgg gtcatcgcaggaggacgaggcctgcgtttgatgcatgctgcaagtgaggatgctgggaga tacacctgcatcgtgtccaactctgctggagaggagcggaagaacttcgacttaaatgtc ctggtgccgcccagcattgtgaacgagggcacagtggaggatttgaaagtgaaggaaaaa cagaacataattttggcctgtgaggtcaccggttatccagttccagagatcacatggctg aaggatgggcaaccattgactagtgacgcaaggatgcaggtgatgtcaaatgggcgtttc cttcagatcagtggatcgcaagtgtccgacacaggcaggtatagctgtctggcctctaac agcgctggagacaggagcagacacttcaacctcaatgtgttggtttctcccaccatcgct ggttctggtccagaaggttcagctgaagaggttactgtgacacttaatagtcctacatct cttgtttgcgaagcccagtcatacccccctgccatcatcacttggctcaaagatggcaca ccctttgaatccagccgcaacgtcagggtacttccaggtggtcgcactttacagatattg aatgctaaagaagaggatgctgggagatatacatgtgtggcgactaacgaggctggagag acactgaagaactatgaggtgaaagttttcgtccctccagttatcaataaaaatgacatc ccaggggagagtctggcccccaaagaggtgaaaattaaagttaacaacacccttacactg gagtgtgaagctcaggctatcccaacacctacgctagtgtggtacaaggatggccagatt ctgaaagcagatggtcacctcagtatcacagcaaacggtcgtatagttcagattaaacac actcaagtgtccgatacaggtcgttacacctgtgtagccaccaacatcgctggagaggat gagaaggactttgatgtaaatatacaagttcccccaagtttccgaggctttggagactct gactctggccttggtaataatggagacgtgaaggatgtgatccttaataatcccttctcc ctgtactgtgagaccaatgccgtcccccctcctgtactcacttggtacaaagatgggcac ctgctgacctctaatgataaaatactcattcttcctggcggaagagtcctccagatccct cgagctcaagcaaaggattctgggagatacacttgtgtggctgtgaatgaggctggagaa gactccatccaatatgatgtcagagtgttgttgccgccctcgattcgtggagctgatggt gacctgcctgatgaggtcacagtgctggttaataagaccacattactggagtgtcaggtg gatggaagtcccactcctaaaattagctggatcaaagacagtcaacccctcaccccagac aacacacacagacttctgtccaatggcaggacactgcagattttgaatgcacaggtgaca gatacaggacgctatgtgtgtgtggctcaaaaccttgctggaacagccgaaaaatcattc aacctccatgtgcatgtgtctccctctattgtcggcatcagagaggagaatgtgactgtg gtggtgaataattttatatctctaaactgtgaggccactggactcccacctcccaccctt agctggttcaaagacaggagacctttacaggccagcaccaacgcactcataatgcctggt ggtcgtactctccagatcctgaaagcaaagatgtctgatggtgggaaatacagctgtgtg gccatgaacccagcaggagaagcccaaaaaataatttatcttacagtatatgtgcccccc agtatcagacacagcagtggggatcttccagtagtgttaaatgtactggtggggaaatct gttactttggagtgtgaatctaatgcagtccctcctcccatcattacctggtataagaat ggacggcccatcactgagactgcacatctgcgcatactggctgatggacaaatgttggaa ctgagagaaacagagttgtcagatactgggcagtatatctgtaaggccacaaatgtagca ggtcaagtggacaagaacttccatctcaacatccatgttcccccacggctggacggccca gcagtggagcgtgtggtggaaaccatcggtaatcctgtcaccttcgcctgtgatgcttca gggatccctcctccctcgcttacctggttgaagaacggcaaagtgattgagaattcagag tctgtggatatgcatatcctgtccgggggcagtaagctgcagattgcccgttcacagtta tctgacagcggcacttacacctgtttggcgtccaatgtggagggcaaggcccgcaaaaac taccaacttataatgcaagtcccaccaatcattgtaggatcagagttacctagtgagatg agtgttctgctgaatgacagcatccagctcgtgtgccgtgctgaaggaactccaacccct gagatccagtggctgaaggatggaaagacacttagcagaactgcccagaagaacatcaaa attagcacggatggtagcactttgactgtgacagccatccacacatctgacagtggaaaa tacacatgtgtggccaccaatcaggctggagaggaagaccgaatattcagcttgaatgta tatgttcctcctcttatccaggggaacggacctgctgccaaggaactgaccgcggtgctg gacagctcaataaatatagagtgtgtagcgagcggttctccacctccacagctcaactgg ctaaagaacagtctgccgcttccaatatcatctcagatccgcctgctgtctgctggccag gtcctccgcattgctcgtgcacaggtttcagatggtgggagctatacttgtgtggcctcc aacagagctggagtggacaacagacactacaaccttcaggtgtatgttcctcccagtttg gacggggcgggcagcacagatgaagtaacagttgtgagaggaaatacggcctctttcatc tgcatttcagatgggatgcccagtccaatcattacttggctaagaaatggtgcagcagta cctaaagatcctcacctgtcactcctcaaccaaaacagcaccctgcagatttctcatgtg agcatcaaccacaccggacgctacacctgtactgcacataatcaggctggggacgcaagc cgccacttcagcctcaaagtactggacccaccacggatcaatgggtctggtgtgcctgct gaggtctctgtggttgtgaatcatgtcttggagctggtttgtgaggccgacggcatacct ttaccaacacttacctggctgaaggatgggcgacctctgcctcagacagacagcatacgg cttctcagagatggagaggtgctcagagttgcctctgctcaggtggagaacactggaaga tacacctgtttggcaaccagccctgctggagatgatgataaagagtttctagtcagagta catgtgccacccaacatcgctggagacacaggtgtgcaagatgtgcttgtactgcaaaac agacaggtgacccttgaatgtaaatcagatgcagttccacctccaactctcacttggctt aaagatggggcaccgctgaagatgtctccacgagtgcgtgttttgtccagcggtcgttat ctgcagatcaacaatgcagagctgagagatggtgcccagtacacttgtgtggccagcaat gttgctggagaaaccagacgccacttcaaccttagtgtcaatgtccctcccacaataaag gatggtcctcaatctgtgttggttaatattcatcaaccagtggttctggagtgtgttgtg aatggagtacccaccccacgcattacctggaggaagcatggatccatcctggcaggaaac aaccccagatacaggtttggtgaggatggttcactccacatcttctcagcccaggtgacc gatacgggccgctacctttgcatggccaccaaccaggcgggaacagagcgcaagagagta gatcttcaggtttatgtgccaccctccattgccgagggtcccactaacatcactgtgact gtgaacgtccagaccacgctatcctgtgaggccactggcatccctaaaccctcagtcagc tggaccaaaaacacccaagcccttaacactgaccagaaccagaatatgtacaggctgttg tcttcaggctctctggttgtcatcgcacctacagtagaggacacagcgctgtacaagtgt gttgtatccaatgaagcaggccaggagagccgagaaattcagctgactgtacatgttcct ccttctattgctgatgaggccacagagcttgtggtgagcagactgtccccggtggtcatt ggctgcactgcatccggagtgcctcatcctgtcctatactggagcaaagatggattgaga ctagctaaaaagggagagggctatacgatactaccgtcaggtcctcttgagatcacagcg gcagatctgagtcactcaggccgttactcttgtgtggccaagaatgctgcaggcacagca caccgacacgttcagctcacagtacacgaacatcctgtgatacagtcacacccatcaaca ctggatgtgattttgaacaatcatgtgaccctgccctgcagagcaatgggctcccctcac ccaactattacctggcagaaagagggtatcaacatttttaccacaggaggtggttttaca gtgctccccaatggtggtctgcagatatctaaagccagagttgaggattctggcacctac atgtgtgtggcacagaatccagcaggcactgcactagggaaaaccaaactcagagttcaa gtacctcctgtcataacttcagacataaaggtgtacactgtggcactagatgcatctgta actctgcaatgccactcagagggcttccccactccttcgatcacctggtacaaggacggg cagccactgagcgagtccatgcaccagcgggtcctcagcacaggggcgctgcagatcgcc ttttcccaacctggagacacaggcagatacacctgcactgctgctaatgtagctggaacc accagtcttgaaatgagccttactgtacacatacctccttccatccgtgtaggagagtca gaggtgtccgtggtggagaacacccaagctttgttgacctgtgtggcagatggggtccca cagcccaccatcacttgggagaaagatgatattgcacttacggacaccactggagaatac acaatcctccccactggagagctgctcatagacactgcacagcctgaggattctgggagt tacacgtgtgttggaaccaactcagttgggcaggacagtcacaccattgatttgtccatc cacacacatccagtcttcactgagctgcttggggatgtggcgctcaacaagggagagcgc ctcctgctggcctgcggcgtcactggcatcccttcacccaagatcacgtgggcattcaac aacaatatcatccctgcccagtatggtcatattaatggccacagtgagcttgtaattgag cgtgtgagtaaagacgactctggcacttattcctgcatggctgagaacagcgtgggatcc atcaaatctctgggatttgtctttgttaaagaaccaccaataatagacggagatgttcat tcaaatcgcattgagcccctgggaggaaatgccatacttgactgtgaggtgcgaggagat cctctgcccaccatccagtggagcaaaaagggcatcaatgtccagataagcaatcgaatc cgtcagcttgacaacggatctctagccatctacggcaccgtgagcgaagatgctggatat tacatgtgtgtggccacaaatgatgcaggagtggtggagagaacagttacactgacctta cagagttctcctaccatcacagtggagcccatagagacagtggtagacgctggttccaca gtgatgttaaactgccaagcagagggagagcctgtgcctgtcattgagtggtcccgtcag gggcgccccctgttgggtaatgagcacatcaccacactgaataacggttctcttcggctc agtagtgcacagaaagaggacacggctgagtatgagtgtgtggcgagaaatttgttaggc tccgtgctggtgcgcgtgaccctaacagtacgagttcatggaggtttctctgaatggatg gagtggggagcctgtagtgtttcctgtggtgcaggagtgcagaggagactgagacagtgc aataacccaattcctgcaaacggaggacgtcactgcattggttcagcaagagaaacacgg agctgtcaaggcaaaccttgcccagtggatggtaattggtccgagtggtcttcctgggag gagtgctctcgttcctgtggtcagggtaacaggactagggtgcggacttgtagtaatcct cctgcccagcatgggggcagagcctgtgagggaaaagcagtggaggccattatgtgtagt ataaggccatgcccagtggcagggaactggggtgcctggttgccttggagcccttgtagt gaaacgtgtggcaaagggatgcagacaagactcagactctgcaacaaccctccgccctca tttgaaggaccctcgtgtgaaggacctgactcacagacacaagtgtgcaatgagaggaat tgccctgtggatggcaagtggtcttcctgggtaagctggggtgcgtgtagtgtttcttgc ggaggcggtacgaggcaaaggacacgtctctgcgcaagccccactccccagcatggggga cggcagtgtgagggaaatgacatccacattgatttctgccacaatgagccctgtcccatt catggtaactggggtccatggaacagctggggcagttgtagcaggacctgcaacggtgga caaatgcgtcgctacagaacctgcgacaatcctcgaccagcaaatggaggcagagcgtgt actggatcagactctcaaatccagaagtgcaacgcagccaactgccctgttgatggtaag tggggttcatgggagtcctggggtgaatgttcagcatcctgtggaggtggagaacggaca cgtgttagactttgtaacaatccatcgcctagcaacagcggccgaccctgcccaggagac tccacccagttatcaagatgtaacatacagccatgtccaggtggccctcagaaagcgaga ggaagtatcattgggaacattaatgatgtggagtttggcattgctatcctcaacgccacc atctctagcagtcccactggagggagagttatacaggccaccatcactaatatacccagg agtctggggtctgctatgaggaagttgatctccatcctgaaccccatttactggaccaca gcacaggagctgggggaagctgtcaatggctacaccctcacagatggcatcttcagacgt gaaactcaggtggagtttgccacaggagagattctccgaatgacgcatgtggcacgaggg ctcgactcagatggagcgcttctgttggacatcgtagtaaacggacacattttgcaactg ccctccaatgcagacatcagtctcaaggactacactgaagactacatccagacgggtcct ggtcagttgtatgctctgtctacacgtatgtttagtatagacagggtcagcgtcccttac tcgtggaatcataccatcacatacggaccttccagaggaaagatgccctatctggtgcag acactccacgcctcggcgatcagcgctctgtaccgaccactagaagagatgctggagttt tccatccatgccactattgctaaaggagagcgcagtaatcagtgtcccagcggttttcag ctgaaccccgctgggccatactgtgcagatgagaatgagtgtgtggacggaaacccctgc tcacatgcctgccacaattctataggcacgtactactgttcctgtcccagaggtctcgcc atctcagctgatggtagaacatgccaggatattgatgagtgttcacagggtgggcacatg tgccatgatggacaagactgtgagaacaccattggctcatatcgctgtgtgatgcgctgt gggcgggggtttaggaggacagctgatgggctgagctgcttagatgtgaatgagtgtcag gaatccaacccttgtcatcagcactgtctaaacaccattggcagcttccgctgtgcttgt gagccgggctaccaactcaggaatcggcgctgtattgacatcaatgaatgcaaacagaga gtgtgtcgctcagatcaacagtgtaaaaacacacgtggtggatacacttgcattgacctc tgccctactggcatgaccaaaggagacaatagcacgtgcatagatattgatgagtgccat gacggcacacatcagtgcaggtataatcagatctgcgaaaacaccagaggtagctaccac tgcacttgcccgagggggtaccgctctcagggtgttggccgcccctgccttgacataaac gagtgcgagctggtaccagtgccctgtgcctatcagtgcgtgaacagccaaggcagctac aagtgcctgtgcccaccggggctccacctgctgggtgatggcaaatcctgtgccggactc gagcgcttgcccaactatgagagtttctcatatgggtacagaacatcacagtcctcctct gatcgaagctcctaccagcagcgctaccatagcctgacttcccagagttaccactcatat gtccccatcggggggcgtcacgtggccaacagaccgaacaatgccccatcacgcagtcgt agggatactaatacctgccctcctggttttaaggcaaaaaatggccagtgtctagatatt aatgaatgtgaacagagggatacatgtcaacatgagtgtatgaacacaccaggcagccat aggtgtttgtgtcccaatggctatcgccttatgagcaatggcaaaacctgccaagacata gatgaatgtctggagcagaacattcagtgtggtgcaaacaggatgtgtttcaacatgaga gggagttaccaatgcatcgacacaccttgccctcccaactatcagagggatccaaccaca gggttctgcctgaagaattgtccacccaatgatctggagtgtgccctgagcccgtatgca ctggagtacaaactgctgtccctgcccttcggcatcgccgccaatcaggacctgatccgg ctggttgcctacacccaggatggagtcatccacccccgcacttccttcttagtggtcgac gaggacacaactctgcccttcgccctccgggacgaaaacctcaaaggtgttctcttcacc actcggcctctgcgcgaacctcacacctaccgcatgaaggtacgagccctgtcttacagt gccgacggaggaatagagtaccagaccaccttcattgtctacatcgctgtctcagcctat ccgtactga

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