Pan paniscus (bonobo): 100972953
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Entry
100972953 CDS
T02283
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pps
Pan paniscus (bonobo)
Pathway
pps01521
EGFR tyrosine kinase inhibitor resistance
pps01522
Endocrine resistance
pps04010
MAPK signaling pathway
pps04012
ErbB signaling pathway
pps04014
Ras signaling pathway
pps04062
Chemokine signaling pathway
pps04068
FoxO signaling pathway
pps04072
Phospholipase D signaling pathway
pps04150
mTOR signaling pathway
pps04151
PI3K-Akt signaling pathway
pps04510
Focal adhesion
pps04540
Gap junction
pps04630
JAK-STAT signaling pathway
pps04650
Natural killer cell mediated cytotoxicity
pps04660
T cell receptor signaling pathway
pps04662
B cell receptor signaling pathway
pps04664
Fc epsilon RI signaling pathway
pps04714
Thermogenesis
pps04722
Neurotrophin signaling pathway
pps04810
Regulation of actin cytoskeleton
pps04910
Insulin signaling pathway
pps04912
GnRH signaling pathway
pps04915
Estrogen signaling pathway
pps04917
Prolactin signaling pathway
pps04926
Relaxin signaling pathway
pps04935
Growth hormone synthesis, secretion and action
pps05034
Alcoholism
pps05160
Hepatitis C
pps05161
Hepatitis B
pps05163
Human cytomegalovirus infection
pps05165
Human papillomavirus infection
pps05200
Pathways in cancer
pps05205
Proteoglycans in cancer
pps05206
MicroRNAs in cancer
pps05207
Chemical carcinogenesis - receptor activation
pps05208
Chemical carcinogenesis - reactive oxygen species
pps05210
Colorectal cancer
pps05211
Renal cell carcinoma
pps05213
Endometrial cancer
pps05214
Glioma
pps05215
Prostate cancer
pps05220
Chronic myeloid leukemia
pps05221
Acute myeloid leukemia
pps05223
Non-small cell lung cancer
pps05224
Breast cancer
pps05225
Hepatocellular carcinoma
pps05226
Gastric cancer
pps05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100972953 (SOS1)
04630 JAK-STAT signaling pathway
100972953 (SOS1)
04068 FoxO signaling pathway
100972953 (SOS1)
04072 Phospholipase D signaling pathway
100972953 (SOS1)
04151 PI3K-Akt signaling pathway
100972953 (SOS1)
04150 mTOR signaling pathway
100972953 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100972953 (SOS1)
04660 T cell receptor signaling pathway
100972953 (SOS1)
04662 B cell receptor signaling pathway
100972953 (SOS1)
04664 Fc epsilon RI signaling pathway
100972953 (SOS1)
04062 Chemokine signaling pathway
100972953 (SOS1)
09152 Endocrine system
04915 Estrogen signaling pathway
100972953 (SOS1)
04917 Prolactin signaling pathway
100972953 (SOS1)
04926 Relaxin signaling pathway
100972953 (SOS1)
04935 Growth hormone synthesis, secretion and action
100972953 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100972953 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
100972953 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100972953 (SOS1)
05206 MicroRNAs in cancer
100972953 (SOS1)
05205 Proteoglycans in cancer
100972953 (SOS1)
05207 Chemical carcinogenesis - receptor activation
100972953 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
100972953 (SOS1)
05231 Choline metabolism in cancer
100972953 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
100972953 (SOS1)
05225 Hepatocellular carcinoma
100972953 (SOS1)
05226 Gastric cancer
100972953 (SOS1)
05214 Glioma
100972953 (SOS1)
05221 Acute myeloid leukemia
100972953 (SOS1)
05220 Chronic myeloid leukemia
100972953 (SOS1)
05211 Renal cell carcinoma
100972953 (SOS1)
05215 Prostate cancer
100972953 (SOS1)
05213 Endometrial cancer
100972953 (SOS1)
05224 Breast cancer
100972953 (SOS1)
05223 Non-small cell lung cancer
100972953 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
100972953 (SOS1)
05160 Hepatitis C
100972953 (SOS1)
05163 Human cytomegalovirus infection
100972953 (SOS1)
05165 Human papillomavirus infection
100972953 (SOS1)
09165 Substance dependence
05034 Alcoholism
100972953 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100972953 (SOS1)
01522 Endocrine resistance
100972953 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
100972953
NCBI-ProteinID:
XP_003817680
Ensembl:
ENSPPAG00000027483
LinkDB
All DBs
Position
12:87342622..87487223
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
TKGTEEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSLSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccctacgagtttttcagcgaagagaacgcgcccaagtggcgg
ggactgctggtgcctgcgctgaaaaaggtccaggggcaagttcatcctactctcgagtct
aatgatgatgctcttcagtatgttgaagaattaattttgcaattattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataaatgggcaatagctgatgcccaatcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtcttagaatacatttctgcagac
attttaaagctggttgggaattatgtaagaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcatcaagatgta
gaagatattaatatattatctttaactgatgaagagccttccacctcaggagaacaaact
tactatgatttggtaaaagcatttatggcagaaattcgacaatatataagggaactaaat
ctaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgcatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatacagtagaaatgacagatgaaggcagtccccatccactagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcgtatgctcga
gatattttgcgacctggttttcatgatcgtttccttagtcagttatcaaagcctggggca
gcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatatgttttaccc
aggctgcttctggcccctgtttaccactgtctccattactttgaacttttgaagcagtta
gaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgtaatgaatttataatggaaggaactcttacacgtgtaggagccaaacacgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcacgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaaggtacaa
attaatgataaagatgacaccaatgaatacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtaacaatgctacag
gaagagaaagaggagcagatgaggctgcctagtgctgatgtttatagatttgcagagcct
gactctgaagagaatattatatttgaagagaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgcaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactgaaaagatttagaaaagaa
tatatacagcctgtgcaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcatatcttttgcaacgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaactctcctaat
cttctgaaaatgattcgacataccaccaacctcactctgtggtttgagaaatgtattgta
gaaactgaaaatttagaagaaagagtagctgtggtgagtcgaattattgagattctacaa
gtctttcaagagttgaacaactttaatggtgtccttgaggttgtcagtgctatgaattca
tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccagaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaagacatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttactgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccgatgggaaatagc
atggagaaggaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctccgcctgcttctggtgcttccagtaccacagat
gtttgcagtgtatttgattccgatcattcgagcccttttcactcaagcaatgataccgtc
tttatccaagttactctgccccatggcccaagatctgcttctgtatcatctataagttta
accaaaggcactgaggaagtgcctgtccctcctcctgttcctccacgaagacgaccagaa
tctgccccagcagaatcttcaccatctaagattatgtctaagcatttggacagtccccca
gccattcctcctaggcaacccacatcaaaagcctattcaccacgatattcactatcagac
cggacctctatctcagaccctcctgaaagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagagagcacacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system
