Pan paniscus (bonobo): 100973447
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Entry
100973447 CDS
T02283
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pps
Pan paniscus (bonobo)
Pathway
pps05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pps00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100973447 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pps03021
]
100973447 (SETX)
Enzymes [BR:
pps01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
100973447 (SETX)
5.6.2.5 RNA 5'-3' helicase
100973447 (SETX)
Transcription machinery [BR:
pps03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
100973447 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
nSTAND3
Motif
Other DBs
NCBI-GeneID:
100973447
NCBI-ProteinID:
XP_034785246
Ensembl:
ENSPPAG00000004108
LinkDB
All DBs
Position
11:6999456..7095610
Genome browser
AA seq
2722 aa
AA seq
DB search
MSTCCWCTPGGASTIDFLKRYASNTLSGEFQTANEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVQVTHSQLEYHVRR
WAILTARNLGKVDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMY
DTTNYKSYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPA
LHCFMVILDRLGSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDM
VTCSQIVYNYNPEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFL
WFIPFVQSLMDLKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELH
RNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSN
SVQLAYVQLIRSLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLK
QIIRNIKFKAPPCNTFVDLTSACKISPASYNKEESEQMGKTSRKDTHCLEASSPTFSKEP
MKVQDSVLIKADNTIEGDNNEQNYMKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKIST
RKQKSVKEISSYTPKDCTSRNGPERGCDRGIIVSTCLLTDSSTDALEKVSTSNEDFSLKD
DALAKTSKRKTKVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDT
GVQKGDGFIHNLSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELDIFSSHENNCKIQEF
HVEDKELIPFTEMTNTSEKKSSPFKDLMTVPESRDEMSNSTSVIYSNLTREQAPDISPKS
DTLTDSQIDRDLHKLSLLAQASVIMFPSDSPQNSSQLQRKVKEDKRCFTANQSNVGDTSR
GQVIIISDSDDDDDDERILSLEKLTKQDKICLERERPEQHVSTVNSKEEKNLVKEEKTET
LFQFEESDSQCFEFESLSEVFSVWRDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSE
VVKKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTN
KRGLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDA
KKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQ
LRDHGKTVGVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRQRLSDCG
STDVKRAGSHTAQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHG
SPATDDACPLNQCDSVVLNGTIPTNEVIVSTSEDPLGGGDPTARHVEMAALKEGEPDSSS
DAEEDNLFLTQNDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKC
KYKDCLETTKNQGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAG
LSKSLETSSALSPSLKNKSKGIQSILKVPQPVGEMKNSCNVLHPQSPNNSNRQGCKVPFG
ESKYSPSSSPVNILFSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRF
HSYGDYFNIFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEEC
ELAKQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKAEC
YLSIQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPVDFCTK
DLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLL
YRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGN
CGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDCQLDELSRQ
RALCRGGREIQKQELDENISKVSKERQQLASKIKEVQGRPQKTQSIIILESHIICCTLST
SGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVIS
MKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNL
KTNRQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKKKDV
SFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSMQG
SIGNSSVPGTLYWDGEFLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSP
FFSPEPKYLHWALKENQHWNQLIQDAQKRGAIIKTCEKNYRHDAVKILKLKPVLQRSLTH
PPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASPYHTPSDSKEITLTVTSKDPERPPVHDQ
LQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHVQQPAAVVA
ALSSHKPPLRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRR
NSRWDKRTLEQEDSSSKKRKLL
NT seq
8169 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtgcttccaccattgacttcctaaagcgc
tatgcttccaacactctgtccggtgaatttcaaacagccaacgaagacctctgctactgc
ttggagtgtgtggctgagtaccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgagttatatatagtagacaacaatggagagatgccactgtttgac
atcactgggcaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttacttgcttctacatgaacgtgttaacgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatttgttttta
gtccatcccaatgaaatggttcaggttacacattcccagctggagtaccatgttcggcgt
tgggctatcttgactgcaagaaacttggggaaagtggacagagatgattattatgactta
caggaagttttactttgcctttttaaagtcattgagttggggcttttagagagtccagac
atttatacttcttctgtcctagagaagggtaaactgattcttctgccctcacacatgtat
gatactaccaactacaaaagctattggttaggtatttgcatgttgctgaccattcttgag
gaacaagccatggattccctgttgttgggctcagacaaacaaaatgattttatgcaatcg
atacttcacactatggagagggaagcagatgatgatagcgtggatcctttctggccagcg
ttacactgttttatggtgattctggatcgccttggatctaaggtctggggtcaacttatg
gatcctattgtggcatttcaaaccattatcaacaacgcaagctacaatagagagatccga
catatacggaacagctctgtaaggaccaagttagaaccggagtcctatttggatgatatg
gtgacttgcagccagatcgtatacaattataatcctgaaaagaccaaaaaggattctgga
tggagaacagccatttgcccagattattgtcctaacatgtatgaagaaatggaaacatta
gccagtgtacttcagtcagatattggtcaagacatgcgtgttcataacagcacatttcta
tggttcatcccttttgtccagtccctcatggatcttaaggatttgggtgtggcttacata
gcacaggttgttaatcatctgtactctgaagtcaaagaagtcctcaaccaaacagatgct
gtgtgtgacaaagtcactgaattttttcttctaattttggtatcagtgattgaactgcat
agaaataaaaaatgtttgcatttgctgtgggtaagttcccagcaatgggtggaagccgtc
gtcaaatgtgccaagcttcctaccactgcgtttacacggagttctgagaaatcatctgga
aattgctccaaaggaacagcaatgatatcttcactgtcgttgcattccatgccatctaac
tctgtacaacttgcttatgtgcagctgattagaagtctccttaaagaaggttatcagctt
gggcagcagtctctttgcaagcgattctgggataagctcaacttattccttagaggaaat
ttatctctaggttggcagttgactagtcaggaaacccatgagctacaaagttgcttaaag
caaattattagaaacataaaattcaaagcacctccatgtaacacttttgtggatctgact
tctgcatgtaaaatctctcctgcatcttataataaagaagaaagtgaacaaatggggaag
acgtctagaaaagatacgcattgtttggaagcttccagcccaacattttctaaagaacca
atgaaagtgcaagacagtgtattgatcaaagcagataacactatagaaggtgacaataat
gagcaaaattatatgaaggatgtgaaactagaagaccatctcttagctgggtcatgctta
aagcagagtagtaaaaacatttttactgaaagagctgaagatcaaattaaaataagtaca
aggaagcagaagtctgtaaaagagatctcttcatatacaccaaaggattgtacttcaaga
aatggtccagaaaggggatgtgacagaggaataatagtatcaacatgtttgttgactgat
tctagcactgatgctttggagaaagtgtccacatcaaatgaagatttctctttaaaggat
gatgctcttgctaaaacctcaaaacgaaaaactaaggtacagaaagatgaaatctgtgca
aagttatcacatgtaataaagaagcaacacaggaagagtactttggtcgataatactatc
aatttagatgaaaatttgactgtatctaacattgagagtttctattcaaggaaagataca
ggagttcagaaaggagatggtttcatacacaatctttctttagaccctagtggtgttctg
gatgataagaatggagaacaaaaatctcaaaacaatgtattgccaaaagagaaacagtta
aagaatgaagaattagatattttctcttcccatgaaaacaattgtaaaatacaggaattt
catgttgaagataaagaattgatcccttttacagaaatgaccaatacttctgagaagaaa
tcatctccctttaaagatcttatgactgtacctgaatcaagagatgagatgagtaatagt
accagtgtgatttattccaacttgacaagagaacaggcccctgacatcagtcctaaatct
gacaccttaacggattctcagatagacagagaccttcacaaattatctttactagctcaa
gccagtgttattatgttcccatccgattcacctcagaactcatcgcagctgcaaaggaaa
gtaaaagaagataaaagatgtttcacagctaaccaaagtaatgttggagatacctcccgt
ggacaggttattattatttcagattctgatgatgatgatgatgatgaaagaatcctgagt
cttgagaaactcactaaacaggacaaaatatgccttgagagggaacgtccagagcagcac
gtttcaacagttaatagtaaggaggaaaagaatctagtaaaggaagaaaagacagagact
ctttttcagtttgaggaatctgattctcagtgttttgagtttgaaagtttatctgaagtg
ttttcagtttggcgagatcatccagacgataataattcagttcaagatggtgagaaaaaa
tgtttggctcctatagccaataccacaaatggtcagggttgtacagattatgtatctgaa
gttgttaaaaaaggagcagagggcattgaagaacacacaagaccacggagtatttctgtt
gaagaattttgtgaaattgaagttaaaaagcctaagagaaaacgatctgaaaaaccaatg
gctgaagatcctgtgaggccttcatcttctgtcagaaatgagggccagtctgatactaat
aagagaggtcttgtgggaaatgattttaaaagtatagatagaaggacttcaactcccaat
tcacgtattcagagagccactacggtttcacaaaagaagtcttcaaagctttgtacttgt
acagaacccatcaggaaagttccagtttctaagacccctaagaaaactcattcagatgcc
aaaaaaggacagaatagaagttcaaattacctaagttgtagaacaactcctgctatagtg
ccgccaaagaaatttcgtcagtgtcctgagccaacttcaacagctgagaaacttggcctg
aaaaagggtcctcgtaaggcatatgagttgtcccagcggtctttggattatgtagctcaa
ttacgtgatcatggcaaaactgttggagtagttgatacccgaaaaaagactaaattaatt
tctcctcagaacctgtctgtcagaaataataagaaacttctgactagtcaagaacttcag
atgcaaaggcagatcagacccaaatcacaaaaaaatagacaaagactttctgattgtgga
agtacagatgttaaaagagcagggtcacatacagcacagaattctgacatatttgtacca
gaatctgataggtcagattataattgtacaggaggaactgaggtactcgccaacagtaac
agaaaacagttaataaaatgcatgccttctgaaccagaaaccataaaagcaaaacatggg
tctccagcaactgatgatgcttgccctttgaaccagtgtgattctgtagtgttaaatgga
acaataccaacaaatgaagtaattgtctctacttcagaggaccctctgggtggaggtgat
ccaacagcacgtcatgtagagatggcagctttgaaagagggagagcctgactccagcagt
gatgcagaggaagataacttatttttaacccaaaatgatcctgaagatatggatttatgt
tcacaaatggagaatgacaattataaactcattgaactaattcatggaaaagatacagtt
gaggttgaagaagattctgtaagtcggcctcagttggaatctttgagtggcacaaagtgt
aagtacaaagattgtcttgaaaccacaaaaaaccagggtgaatactgcccaaaacactct
gaagtgaaagcagcagatgaagatgtatttcgtaaacctggcttgcctcctcctgcatct
aaacctttgagacctaccactaagatttttagctcaaagagtacttcacgaattgctggt
ctttctaaatctttggaaacttcttcagcactttcaccgtctctaaaaaataagtcaaag
gggatacagtcgattttgaaagtaccacagccagttggtgaaatgaagaattcgtgcaat
gttcttcatcctcagtctccgaataattccaacaggcaaggttgcaaagttccatttggt
gaaagcaaatattctccatcttcctctccagtaaacattcttttttcatcacagtctgtc
tctgacaccttcgttaaagaggtcttaaaatggaaatatgaaatgtttttgaactttggt
cagtgtgggccccctgcaagtctttgtcagtccatctcaagacctgtgcctgtcagattt
cacagttatggagattattttaatatttttttccctttgatggtattgaatacttttgaa
acagtggcacaggaatggctcaactctccaaatagagagaatttctatcagttgcaagta
cgaaaatttcctgccgattatataaaatactgggagtttgcagtttatctggaagaatgt
gaactggctaaacagctttatccaaaggaaaacgatttggtgtttttagctcctgagaga
ataaatgaagagaagaaagatacagagagaaatgacatacaagatctccatgaatatcat
tctggttatgttcataaatttcgccgcacttcagtcatgcgtaatgggaaagctgagtgt
tacctttccatccagactcaagagaactttccggccaatttaaacgaacttgtgaattgt
attgtaatcagttctctggtaactacacaaaggaagttgaaagccatgtctctgttgggt
agtcggaaccaactggctagagctgttctgaatccaaaccctgtggacttctgtacaaaa
gatttactgactacaacatctgagagaattattgcgtacttaagagatttcaatgaagac
caaaagaaagcaatagaaactgcatatgctatggtgaaacactcaccatcagttgccaaa
atctgcttgattcatggaccacctggaacaggaaaatcaaaaactattgttggcctcctc
tatcgtctactgacagagaaccagaggaaggggcattcagacgaaaactccaatgccaaa
atcaaacaaaaccgtgtcctcgtgtgtgcaccttccaatgcagctgttgatgaactcatg
aaaaaaattatccttgaattcaaagaaaaatgtaaagacaagaagaatcctttaggaaac
tgtggagatataaatttagtacgactgggtccagaaaagtctattaatagtgaggttcta
aagttcagtttggacagccaagtaaaccacagaatgaaaaaagagttaccttctcatgtt
caggcgatgcataaaagaaaggaatttctagattgtcagctggatgagctttcccggcag
cgagctctatgccgaggtggacgggaaatacagaagcaagaattagatgaaaacatttcc
aaagtttctaaggaaaggcagcaacttgcttctaaaattaaagaggttcaaggacgccca
cagaaaacacagagtatcatcatcttagagtcccatatcatctgctgcacgttgagcaca
agtggtggtttactacttgagtctgctttccgtgggcaagggggtgtccccttcagctgt
gtcattgttgatgaggctggacagtcttgtgaaattgagactcttactccactcatccat
cgctgcaataagctcatcctagtaggagatcctaagcagctccctcccacagtcatctct
atgaaagcacaggagtatggctacgaccagtcaatgatggctcgcttctgcagactgctg
gaagagaatgtagaacacaacatgatcagcaggctgcccattctacagctcactgttcag
tacaggatgcatccagacatatgcctcttcccttctaattatgtttataacagaaactta
aaaacaaatagacagacagaagccattcgatgttcatcagactggccatttcagccatac
cttgtgtttgatgttggagatggttcagaaagacgggataatgactcatatataaatgtt
caagaaataaaactggtgatggaaataattaagcttattaaagacaaaaaaaaggatgtt
agttttcgaaacattggcataataactcattacaaggcccagaagacgatgattcagaag
gatttggacaaagagttcgatagaaaaggaccagcagaagtagacactgtggatgcattc
cagggtcggcagaaggattgtgttattgttacgtgtgtcagagcaaatagcatgcaaggt
tcaattgggaattcttctgtgcccggtaccctgtattgggacggagaattcctggcaagt
ttgcagagattgaatgtcaccatcacacgagccaagtacagcctcttcatcctcggacat
ttgaggaccctgatgcaacttcttcctaggagcttttgtgtacacgtgaaccattcgcct
tttttcagcccagaacccaagtatctacactgggctctcaaggaaaaccagcattggaat
cagctgattcaggatgctcagaagcgtggtgccattattaagacctgtgagaaaaactat
agacatgatgcagtgaagattctgaaactcaagcctgtgctgcagagaagtctcactcac
cctcctaccatagccccagaggggtccagaccccagggtggtttgcccagcagcaagcta
gacagtggatttgccaagacatctgttgctgcttctccataccacacaccctctgactcc
aaggaaattactcttactgttacttcaaaggaccctgaaagacctcctgttcatgaccaa
cttcaggacccacgactgctgaagaggatgggcattgaggtcaaaggaggaatattcctt
tgggatccacaaccctcgagcccccagcatcctggagcaacacctcctacgggcgagccg
ggcttccctgtcgttcaccaggacctgagccatgtacagcagcccgctgctgtagtggct
gctctgagcagccacaaacctcccttgcggggcgaacctccagctgccagtcccgaggct
tccacgtgtcagagcaaatgtgatgacccggaagaggagctctgtcacaggagagaggcc
agggctttcagtgagggggagcaggagaagtgtggctccgagacccatcacaccaggagg
aactctaggtgggacaagaggacactggagcaggaggacagcagttccaagaaaagaaag
cttttatag
DBGET
integrated database retrieval system
